Clinical Trials on Esophagitis in United Kingdom

Total 318 results

Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of 5, 10 or 25 mg of YF476 Daily for 14 Days on Stomach Acidity in Healthy Volunteers

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of Single Rising Doses of YF476, a Gastrin Antagonist, in Healthy Men

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Reflux Oesophagitis

United Kingdom
Portsmouth Hospitals NHS Trust
University of Portsmouth

Unknown

Aceto-whitening in the Assessment of Gastrointestinal Neoplasia

Barrett Esophagus | Barrett Adenocarcinoma | Barrett Metaplasia | Barrett Oesophagitis With Dysplasia

United Kingdom
GlaxoSmithKline

Completed

Intravenous Mepolizumab In Children With Eosinophilic Esophagitis

Oesophagitis, Eosinophilic

United States, Canada, United Kingdom, Australia
AQILION AB

Completed

SAD, MAD and Food Effect Evaluation of Safety, Tolerability, and PK of AQ280 in Healthy Subjects

Eosinophilic Esophagitis (EoE)

United Kingdom
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial)

Eosinophilic Oesophagitis

United States, Canada, Israel
Takeda

Completed

TAK-438 - Safety, Blood Levels & Effects of Repeated Doses (TAK-438_107)

Gastroesophageal Reflux Disease (GERD) | Erosive Esophagitis(EE)

United Kingdom
University of Cambridge

Completed

Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's Oesophagus (MuSE)

Esophageal Neoplasms | Barrett Esophagus | Reflux Esophagitis

United Kingdom
St George's, University of London
University Hospital Southampton NHS Foundation Trust; St George's University...

Recruiting

Eosinophilic Oesophagitis Assessment With String Testing (EoEAST)

Eosinophilic Esophagitis

United Kingdom
University of Kansas Medical Center
University of Texas, Southwestern Medical Center at Dallas

Recruiting

Itraconazole to Prevent Recurrent Barrett's Esophagus

Barrett Oesophagitis With Dysplasia

United States
Manchester University NHS Foundation Trust

Completed

A Validation Study of the Dx-pH Probe in Children for the Detection of Extra-oesophageal Reflux

Gastro-oesophageal Reflux

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Assessment of Gastro-esophageal Reflux Using Endo-Flip vs Bravo

Heartburn | Gastro-esophageal Reflux

United Kingdom
Yvonne Romero
Bausch Health Americas, Inc.

Completed

Impact of Timing on the Efficacy of Zegerid 40 mg in Healing Reflux Esophagitis: A Pilot Study

Erosive Esophagitis

United States
Mayo Clinic

Completed

Proton Pump Inhibitor (PPI) Therapy for Newly Diagnosed Esophagitis (EE)

GERD | Erosive Esophagitis | Reflux Esophagitis

United States
Jiangsu Carephar Pharmaceutical Co., Ltd.

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of Oral Doses of H008

Erosive Esophagitis

United States
Vanderbilt University Medical Center

Completed

Biology in Patients With Reflux Esophagitis (BENCH)

GERD

United States
Royal Brompton & Harefield NHS Foundation Trust

Unknown

The Role of Gastroesophageal Reflux in Scleroderma Pulmonary Fibrosis

Gastroesophageal Reflux | Systemic Sclerosis | Interstitial Lung Disease

United Kingdom
Phathom Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Erosive Esophagitis

Erosive Esophagitis

United States, Poland, Bulgaria, United Kingdom, Czechia, Hungary
Memorial Sloan Kettering Cancer Center

Recruiting

Reducing Acute Upper Gastrointestinal Side-Effects of Thoracic Irradiation

Radiation Esophagitis

United States
Children's Hospital of Philadelphia

Recruiting

Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy

Eosinophilic Esophagitis (EoE)

United States
Cinclus Pharma AG
Parexel

Completed

A Study in Patients With Erosive Esophagitis to Investigate Safety, Tolerability, and Healing Rates After 4 Weeks Treatment of X842 or Lansoprazole and Symptom Pattern During Subsequent 4 Weeks Treatment With Lansoprazole

Erosive Esophagitis

Poland, Bulgaria, Serbia, Georgia, United States, Czechia, Hungary, Ukraine
University of Iowa

Terminated

Bethanechol for Eosinophilic Esophagitis

Eosinophilic Esophagitis (EoE)

United States
Takeda

Recruiting

A Study of Dexlansoprazole in Healing and Maintenance of Healed Erosive Esophagitis (EE) in Children

Erosive Esophagitis

United States, Lithuania, Mexico, Canada, Colombia, Poland
AstraZeneca
Laboratory Corporation of America; Medidata Solutions; IQVIA RDS Inc.; Calyx; Thermo... and other collaborators

Recruiting

Endoscopic Evidence of Maintenance of Healing With Oral NEXIUM in Patients 1 to 11 Years Old With Erosive Esophagitis. (EE)

Erosive Esophagitis

United States, Italy, Belgium, Vietnam, Spain, Portugal, Russian Federation, Argentina, Greece, Australia, Lithuania
Queen Mary University of London

Unknown

Identification of Autoantigens in EGPA and Severe Eosinophilic Asthma (IDEA)

Eosinophilic Esophagitis | Churg-Strauss Syndrome | Eosinophilic Asthma | Eosinophilic Pneumonia

United Kingdom
AstraZeneca

Completed

A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients With Erosive Esophagitis.

GERD With Erosive Esophagitis

Sweden, United States, France, Italy, United Kingdom, Germany, Denmark, Finland, Norway, Canada
Columbia University

Completed

Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome (Mouthwash)

Barrett's Esophagus | Esophageal Adenocarcinoma | Reflux Esophagitis

United States
AstraZeneca

Completed

A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients Without Erosive Esophagitis.

GERD Without Erosive Esophagitis

Sweden, United States, France, Italy, United Kingdom, Germany, Denmark, Finland, Norway, Canada
Braintree Laboratories

Recruiting

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis

Erosive Esophagitis

United States
Mayo Clinic

Completed

Eating With Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis (EoE)

United States
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR on Maintaining Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States
Takeda

Completed

Comparison of Dexlansoprazole MR to Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States
Rush University Medical Center

Recruiting

Esomeprazole and Radiation Induced Esophagitis (EERENs)

Locally Advanced Lung Carcinoma | Radiation Esophagitis

United States
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Poland, Bulgaria, India, Canada, Peru, Russian Federation, Australia, New Zealand, Czech Republic, Slovakia, South Africa, Latvia, Lithuania, Colombia, Germany
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR Compared to Placebo on Maintaining Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Canada, Czech Republic, Lithuania, Slovakia, Latvia, Estonia, Australia
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Poland, Bulgaria, India, South Africa, Canada, Peru, New Zealand, Australia, Lithuania, Slovakia, Hungary, Latvia, Germany, Czech Republic
Vanderbilt University
Takeda

Completed

Study of the Efficiency of Esophageal Dilation on Patient With Eosinophilic Esophagitis (EOE)

Suspected Eosinophilic Esophagitis

United States
Dallas VA Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

The Role of HIF-2a in the Pathogenesis of Reflux Esophagitis

Esophagitis | Gastroesophageal Reflux Disease | Reflux Esophagitis

United States
AstraZeneca

Completed

NEXIUM® in the Treatment of Moderate and Severe Erosive Esophagitis

Gastroesophageal Reflux Disease | Erosive Esophagitis | Reflux Esophagitis

United States
Shire

Completed

Dose-Ranging Study of Oral Viscous Budesonide in Pediatrics With Eosinophilic Esophagitis

Eosinophilic Esophagitis (EoE)

United States
Shire

Completed

OBS in Adolescent and Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an Open Label Extension

Eosinophilic Esophagitis (EoE)

United States
Regeneron Pharmaceuticals
Sanofi

Active, not recruiting

Study to Investigate the Efficacy and Safety of Dupilumab in Pediatric Patients With Active Eosinophilic Esophagitis (EoE) (EoE KIDS)

Eosinophilic Esophagitis (EoE)

United States, Canada
Pfizer

Recruiting

Protonix Treatment of Maintenance of Healing in Pediatric Participants Aged 1-11 Years and 12-17 Years

Esophagitis

Belgium, United States, United Kingdom, Serbia, Georgia, Hungary, Puerto Rico, Turkey, Slovakia, India, Bosnia and Herzegovina
Mayo Clinic

Completed

Proton Pump Inhibitor (PPI) Responsive Eosinophilic Esophagitis EoE: Gastroesophageal Reflux Disease (GERD) or Eosinophilic Esophagitis (EoE)?

Erosive Esophagitis

United States
AstraZeneca

Completed

Esomeprazole for Treatment of GERD in Pediatric Patients

Gastroesophageal Reflux Disease (GERD) | Erosive Esophagitis | Non-erosive Esophagitis

United States, France, Italy, Belgium
Celldex Therapeutics

Recruiting

A Study of CDX-0159 in Patients With Eosinophilic Esophagitis (EvolvE)

Eosinophilic Esophagitis

United States, Spain, Australia, United Kingdom, Canada, Italy, Poland, Germany
Shire
Takeda Development Center Americas, Inc.

Terminated

Continuation Study With Budesonide Oral Suspension (BOS) for Adolescent and Adult Participants With Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis (EoE)

United States
Shire

Completed

An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE) (ORBIT2)

Eosinophilic Esophagitis (EoE)

United States

Clinical Trials on Esophagitis in United Kingdom

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