Clinical Trials on Familial Hypercholesterolemia - Homozygous

Total 2160 results

Aegerion Pharmaceuticals, Inc.

Completed

Evaluate Safety and Efficacy of AEGR-733 and Atorvastatin vs Atorvastatin Monotherapy in Hypercholesterolemia

Hypercholesterolemia

United States
University Hospital of Ferrara

Completed

Nutraceutical in Cardiovascular Primary Prevention (NIRVANA)

Hypercholesterolemia

Italy
Foundation for Atlanta Veterans Education and Research...
AstraZeneca

Completed

Effect of Crestor on Lipoprotein Metabolism in Humans

Hypercholesterolemia

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Effect of Alirocumab on Lipid Metabolism in Adults With Elevated LDL-Cholesterol

Hypercholesterolemia

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy (MK-0859-021)

Hypercholesterolemia
University of Bologna

Completed

Effect of Red Yeast Rice, Phytosterols and L-tyrosol on Lipid Profile and Endothelial Function

Hypercholesterolemia

Italy
Danone Spain

Completed

Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (Spain)

Hypercholesterolemia

Spain
Danone Research

Completed

Effects of Lactobacillus Delbruckii Lactis DN111244 Fermented Milk Consumption on Plasma Lipids Levels in Hypercholesterolaemic Adults

Hypercholesterolemia

Czech Republic
Daewon Pharmaceutical Co., Ltd.

Completed

Phase 3 Study to Evaluate the Efficacy and Safety of the DW0929 in Patients With Primary Hypercholesterolemia

Hypercholesterolemia

Korea, Republic of
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) in Patients With Primary Hypercholesterolemia on Stable Atorvastatin Therapy in Japan

Hypercholesterolemia

Japan
Sanofi
Regeneron Pharmaceuticals

Completed

Effect of Alirocumab (SAR236553/REGN727) Administered on Top of Ezetimibe or Fenofibrate on Lipid Profiles in Healthy Subjects

Hypercholesterolemia

France
Yonsei University

Completed

Nattokinase Supplementation and Hemostatic Factors

Hypercholesterolemia

Korea, Republic of
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Tolerability of Varying Load and Dose of ISIS 301012 in People With Elevated LDL-cholesterol Levels

Hypercholesterolemia

Germany
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Dose-escalating Safety Study in Subjects on Stable Statin Therapy

Hypercholesterolemia

Netherlands, United States
Sanofi

Terminated

Evaluation of Efficacy and Safety of AVE5530 Co-administered With Atorvastatin in Primary Hypercholesterolemia

Hypercholesterolemia

United States, Puerto Rico
Sanofi

Terminated

Evaluation of Safety and Efficacy of AVE5530 as add-on to Ongoing Statins in Patients With Primary Hypercholesterolemia

Hypercholesterolemia

United States, France, Canada, Poland, Russian Federation, Germany, Netherlands, Spain, Sweden, Belgium, Czech Republic, Denmark, Hungary, Israel, Norway, Australia
Cardinal Tien Hospital

Completed

Evaluation of the Effects of Simvastatin 40mg

Hypercholesterolemia
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) When Co-administered With High Dose of Atorvastatin in Patients With Primary Hypercholesterolemia

Hypercholesterolemia

United States
NYU Langone Health

Completed

Using Nudges to Implement Comparative Effectiveness

Hypercholesterolemia

United States
Sun Yat-sen University

Completed

Retinoic Acid Supplementation and Subjects With Hypercholesterolemia

Hypercholesterolemia

China
US Department of Veterans Affairs
University of Pittsburgh

Completed

Systematic Management of High Cholesterol Utilizing Computer Monitoring

Hypercholesterolemia

United States
Daiichi Sankyo, Inc.

Completed

A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Pravastatin for at Least 4 Weeks.

Hypercholesterolemia

United States
Daiichi Sankyo, Inc.

Completed

A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Simvastatin for at Least 4 Weeks.

Hypercholesterolemia

United States
Regeneron Pharmaceuticals
Sanofi

Completed

Ascending Multi-dose Study of REGN727(SAR236553) With and Without Concomitant Atorvastatin

Hypercholesterolemia

United States
Tufts University

Completed

Soybean Based Diets and CVD Risk Factors

Hypercholesterolemia

United States
Gachon University Gil Medical Center

Completed

Vascular and Metabolic Effects of Vytorin

Hypercholesterolemia

Korea, Republic of
Micropharma Limited

Completed

Efficacy of a One-a-Day L. Reuteri NCIMB 30242 Probiotic Supplement Capsule

Hypercholesterolemia

Canada
Comitato Etico di Area Vasta Sud Est
Carla Caffarelli

Completed

Long Term Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols and Berberine) in Low-moderate Risk Hypercholesterolemic Patients: a Double-blind, Placebo Controlled Study

Hypercholesterolemia
Aalborg University Hospital

Completed

Cholesterol Lowering Treatment With Psyllium Husks and Isolated Soy Protein in Hypercholesterolemia (ProFi)

Hypercholesterolemia

Denmark
AstraZeneca

Completed

Observational Study to Understand Patients' and Physicians' Attitudes to Statins in TurkeY (STAY)

Hypercholesterolemia

Turkey
Seoul National University Hospital
Yuhan corp., Seoul, Korea

Completed

The Efficacy and Safety of Atorva® 20mg Versus Lipitor® 20mg

Hypercholesterolemia

Korea, Republic of
Uppsala University
Lund University; Arla Foods; Vinnova; The Swedish Research Council for Environment... and other collaborators

Completed

Role of Milk Fat Globule Membranes in Dairy Foods: Health Effects in Humans (MFGM)

Hypercholesterolemia

Sweden
Sanofi
Regeneron Pharmaceuticals

Completed

Injection Site Tolerability, Safety, Pharmacokinetics and Pharmacodynamics Study After a Single Dose Subcutaneous Treatment of Alirocumab SAR236553 (REGN727)

Hypercholesterolemia

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Pharmacokinetic and Tolerability of Alirocumab SAR236553 (REGN727) in Patients With Hepatic Impairment and in Healthy Subjects

Hypercholesterolemia

Moldova, Republic of, France
Sanofi
Regeneron Pharmaceuticals

Completed

Injection Site Tolerability, Safety, Pharmacokinetics, Pharmacodynamics in Different Single-Dose Treatments of Alirocumab SAR236553 (REGN727) in Healthy Subjects

Hypercholesterolemia

United States
University of Jena
German Federal Ministry of Education and Research

Completed

Cholesterol-lowering Effects of Lupin Protein

Hypercholesterolemia

Germany
Mayo Clinic

Completed

Statin Interchange by Pharmacist Collaborative Practice Agreement (CPA)

Hypercholesterolemia

United States
AstraZeneca

Completed

Centralized Pan-Middle East Survey on the Undertreatment of Hypercholesterolemia (CEPHEUS)

Hypercholesterolemia
Takeda

Completed

Efficacy of Lapaquistat Acetate Alone or Combined With Rosuvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States, Canada
Marjukka Kolehmainen
Raisio Plc

Completed

Effect of High Stanol Ester Dose on Serum Lipids, Carotenoids and Fat-soluble Vitamins (maxsta)

Hypercholesterolemia

Finland
AstraZeneca

Completed

Polish Survey on the Efficacy of the Hypercholesterolemia Treatment (CEPHEUS)

Hypercholesterolemia
Azienda Ospedaliera Brotzu

Completed

Cheese Intake and Hypercholesterolemia

Hypercholesterolemia
AstraZeneca

Completed

Compare the Efficacy of Rosuvastatin to Atorvastatin in High Risk Patients With Hypercholesterolemia

Hypercholesterolemia

China
Santaris Pharma A/S

Terminated

Multiple Ascending Dose Study of SPC5001 in Treatment of Healthy Subjects and Subjects With FH

Hypercholesterolemia

Netherlands
Sunnybrook Health Sciences Centre
Merck Frosst Canada Ltd.; Schering-Plough

Terminated

INdians Followed for INtensive Lipid Lowering Treatment and Its safetY (INFINITY)

Hypercholesterolemia

Canada
Hadassah Medical Organization

Unknown

The Effect Of Simvastatin On Bone Remodeling In Socket Of Mandibular Teeth

Hypercholesterolemia

Israel
Yonsei University

Completed

A Clinical Trial Study to Evaluate Efficacy and Safety of Atorvastatin in Korean Patients With Hypercholesterolemia

Hypercholesterolemia

Korea, Republic of
AstraZeneca

Withdrawn

Effect of an Internet Based Compliance Enhancement Tool in Subjects With Hypercholesterolemia

Hypercholesterolemia

Denmark
AstraZeneca

Completed

Comparing the Efficacy and Safety of Rosuvastatin With Atorvastatin and Simvastatin (SOLAR) (SOLAR)

Hypercholesterolemia
AstraZeneca

Completed

STELLAR-Rosuvastatin vs. Atorvastatin, Pravastatin, Simvastatin Across Dose Ranges (STELLAR)

Hypercholesterolemia

3

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