Clinical Trials on Fat Hepatic Overload in New Zealand

Total 3642 results

AbbVie

Completed

Pharmacokinetics and Safety of ABT-493 and/or ABT-530 in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment

United States, New Zealand
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
Prehospital Center, Region Zealand

Not yet recruiting

Patients Treated by the Danish Emergency Medical Services Following Non-drowning Water Rescues From 2016 to 2023 (RESCUE)

Drowning | Drowning, Near | Submersion | Submersion - Accidental | Submersion or Drowning Due to Being Washed Overboard | Submersion or Drowning Due to Being Thrown Overboard | Submersion or Drowning Due to Ship Sinking, Water Skier Injured | Submersion or Drowning Due to Boat Submerging, Swimmer... and other conditions

Denmark
ApoPharma

Completed

Safety and Acceptability of Deferiprone Delayed Release Tablets in Patients With Systemic Iron Overload (TWICE)

Iron Overload Due to Repeated Red Blood Cell Transfusions

United States, Canada, Greece, Italy
Liggins Institute

Recruiting

Newborn Genomics Programme

Genetic Disease | Newborn Morbidity

New Zealand
Northwell Health
Novartis

Completed

Iron Overload in Pediatric Oncology Patients

Iron Overload

United States
Novartis Pharmaceuticals

Completed

A Protocol to Allow Treatment With ICL670 for Patients With or at Risk of Life-threatening Complications of Transfusional Iron Overload Who Are Unable to Tolerate Other Iron Chelators Because of Documented Severe Toxicity

Transfusional Iron Overload

United States, Greece, Italy
Conatus Pharmaceuticals Inc.

Completed

PK and PD Study of IDN-6556 in Subjects With Hepatic Impairment and Matched Healthy Volunteers

Liver Diseases | Digestive System Diseases | Hepatic Impairment

United States
Shire

Terminated

Pharmacokinetics of SSP-004184 in the Treatment of Chronic Iron Overload Requiring Chelation Therapy

Iron Overload Due to Repeated Red Blood Cell Transfusions

United States, Canada, Lebanon, Italy, Egypt
Tavotek Biotherapeutics

Recruiting

A Study of TAVO101 in Atopic Dermatitis Patients

Atopic Dermatitis

New Zealand
Eli Lilly and Company

Recruiting

A Study of LY3437943 in Participants With Impaired and Normal Liver Function

Hepatic Insufficiency | Healthy

United States
Arrowhead Pharmaceuticals

Recruiting

Study of ARO-DUX4 in Adult Patients With Facioscapulohumeral Muscular Dystrophy Type 1

Facio-Scapulo-Humeral Dystrophy

New Zealand
ReCode Therapeutics

Recruiting

A Phase 1 Study Evaluating Safety and Tolerability of RCT2100 in Healthy Participants

Cystic Fibrosis

New Zealand
Arcturus Therapeutics, Inc.
Novotech CRO

Recruiting

Safety, Tolerability, and Pharmacokinetics of ARCT-032 in Healthy Adult Subjects and Adults With Cystic Fibrosis.

Cystic Fibrosis

New Zealand
Sequana Medical N.V.

Recruiting

Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0 (MOJAVE)

Heart Failure | Volume Overload

United States
Arthrosi Therapeutics

Completed

Phase 2a Study of AR882 Alone and in Combination With Febuxostat or Allopurinol in Gout Patients

Gout Patients

New Zealand
Institute of Liver and Biliary Sciences, India

Withdrawn

High Volume Plasmapheresis for Refractory Hepatic Encephalopathy in Liver Intensive Care Unit.

Refractory Hepatic Encephalopathy

India
PAVmed Inc.

Completed

PAVmed CarpX Device Clinical Study

Carpal Tunnel Syndrome

New Zealand
Arcturus Therapeutics, Inc.

Completed

Safety, Tolerability and Pharmacokinetics of ARCT-810 in Healthy Adult Subjects

Ornithine Transcarbamylase Deficiency

New Zealand
Protalix

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid Levels

Gout

New Zealand
Vital Therapies, Inc.

Withdrawn

Safety and Efficacy of the Extracorporeal Liver Assist Device (ELAD®) In Patients With Fulminant Hepatic Failure (FHF) (ELAD)

Fulminant Hepatic Failure

United States
DePuy International

Completed

A Randomised Single Centre Study to Compare the Long-term Wear Characteristics of Marathon™ and Enduron™ Polyethylene Cup Liners in Primary Total Hip Replacement

Osteoarthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

New Zealand
Yale University

Completed

Zero Sodium Peritoneal Dialysate Protocol Pilot Study

Potential Applications for Heart Failure | Volume Overload

United States
Dicerna Pharmaceuticals, Inc.

Withdrawn

An Extension Study of Belcesiran in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATLD)

Alpha 1-Antitrypsin Deficiency

New Zealand
Arrowhead Pharmaceuticals

Completed

Study of ARO-AAT in Normal Adult Volunteers

Alpha 1-Antitrypsin Deficiency

New Zealand
Australian and New Zealand Intensive Care Research...
Melbourne Health; The Alfred; Barwon Health; Wellington Hospital; Monash Health; Austin... and other collaborators

Completed

The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial (VITAMINS)

Sepsis | Shock, Septic | Critically Ill | Vasoplegic Syndrome

Australia, New Zealand, Brazil
SurModics, Inc.

Active, not recruiting

Safety and Efficacy of the SurVeil™ Drug-Coated Balloon (AVess FIH)

Hemodialysis Access Failure

Australia, New Zealand
Taiho Oncology, Inc.

Completed

Evaluating Patients With Impaired Hepatic Function

Impaired Hepatic Function

United States
Gilead Sciences

Completed

Open-Labeled Study of PSI-7977 and RBV With and Without PEG-IFN in Treatment-Naïve Patients With HCV GT2 or GT3

Chronic Hepatitis C Infection

New Zealand
Novartis Pharmaceuticals

Completed

Phase II Study to Investigate the Benefits of an Improved Deferasirox Formulation (Film-coated Tablet)

Chronic Iron Overload Due to Transfusion-dependant Anemias

Italy, Austria, Thailand, Spain, Germany, Mexico, Malaysia, Greece, United Kingdom, France, Saudi Arabia, United Arab Emirates, Lebanon, Russian Federation, United States, Argentina
Conatus Pharmaceuticals Inc.

Completed

A Trial of IDN-6556 in Post Orthotopic Liver Transplant for Chronic HCV (POLT-HCV-SVR)

Liver Cirrhosis | Hepatic Fibrosis | Liver Fibrosis | Hepatic Cirrhosis

United States
Columbia University

Completed

High-Tc Susceptometer to Monitor Transfusional Iron Overload

Myelodysplastic Syndromes | Sickle Cell Disease | Aplastic Anemia | Transfusional Iron Overload | Thalassemia Major

United States
Novartis Pharmaceuticals

Completed

ENTRUST, a 5 Year Surveillance of Children Aged 2 to <6 Years With Transfusional Iron Overload Treated With Deferasirox

Anemia

United States
Abbott

Completed

A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]

Hepatic Encephalopathy

India
Govind Ballabh Pant Hospital

Unknown

Trial Comparing Sedation for Endoscopy With Propofol Versus Midazolam in Cirrhotics

Hepatic Encephalopathy

India
Institute of Liver and Biliary Sciences, India

Completed

Rifaximin Plus Lactulose Versus Lactulose Alone for the Treatment of Hepatic Encephalopathy: a Double Blind Randomized Trial

Hepatic Encephalopathy

India
Arrowhead Pharmaceuticals

Recruiting

Study of ARO-DM1 in Subjects With Type 1 Myotonic Dystrophy

Myotonic Dystrophy 1

New Zealand, Australia
Novartis

Completed

Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function

Hepatic Insufficiency

United States
NYU Langone Health
Bausch Health Americas, Inc.

Terminated

The Role of Bacterial Overgrowth and Delayed Intestinal Transit in Hepatic Encephalopathy.

Hepatic Encephalopathy

United States
Ocera Therapeutics, Inc.

Completed

Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE) (STOP-HE)

Hepatic Encephalopathy | Acute Episode of Overt Hepatic Encephalopathy

Belgium, Germany, Italy, Spain, United States, France, Austria, Russian Federation, Czechia, Australia, Hungary, Israel, Netherlands, Bulgaria, Estonia, Denmark, New Zealand
Novartis Pharmaceuticals

Completed

Palatability and Tolerability of Deferasirox Taken With Meals, With Different Liquids or Crushed and Added to Food

Transfusional Hemosiderosis

United States
Cystetic Medicines, Inc.
DevPro Biopharma

Recruiting

Study to Assess Amphotericin B Cystetic for Inhalation (ABCI) Doses in Healthy Volunteers & People With Cystic Fibrosis (ABCI)

Cystic Fibrosis

Australia, New Zealand
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Completed

Study of DCR-A1AT in Healthy Adult Volunteers

Alpha 1-Antitrypsin Deficiency

New Zealand, Sweden
Ocera Therapeutics

Completed

AST-120 Used to Treat Mild Hepatic Encephalopathy (ASTUTE)

Mild Hepatic Encephalopathy

United States
Monash Medical Centre
Monash University; University of Auckland, New Zealand; Hudson Institute of Medical... and other collaborators

Recruiting

Anakinra for Preterm Infants Pilot

Inflammation | Prematurity; Extreme

Australia, New Zealand
Bausch Health Americas, Inc.

Completed

Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the Treatment of Overt Hepatic Encephalopathy (OHE) (OHE)

Overt Hepatic Encephalopathy

United States
Govind Ballabh Pant Hospital

Completed

S. Endotoxin, Inflammatory Mediators and MRS Before and After Treatment in MHE (endtxninHE)

Hepatic Encephalopathy

India
Govind Ballabh Pant Hospital

Unknown

Primary Prophylaxis of Hepatic Encephalopathy in Patients With Cirrhosis

Hepatic Encephalopathy

India
Institute of Liver and Biliary Sciences, India

Unknown

To Compare Efficacy and Safety of Lactulose Versus Polyethylene Glycol for Treatment of Overt Hepatic Encephalopathy in Cirrhotics.

Cirrhosis

India
Eli Lilly and Company

Completed

A Study of Tirzepatide in Participants With Impaired Liver Function

Hepatic Insufficiency

United States

Clinical Trials on Fat Hepatic Overload in New Zealand

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CROs in Hungary

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