Clinical Trials on Fatal Familial Insomnia

Total 3410 results

Oregon Health and Science University

Completed

Improving Sleep Quality in People With Insomnia

Primary Insomnia | Psychophysiological Insomnia

United States
University of Rochester
Sanofi-Synthelabo

Completed

Long Term Treatment With Zolpidem: Nightly and Intermittent Dosing

Insomnia | Primary Insomnia | Psychophysiologic Insomnia

United States
National Medical Research Center for Therapy and...
Moscow State University of Medicine and Dentistry

Recruiting

Genetic Testing and Motivational Counseling for FH (GENMOTIV-FH)

Medication Adherence | Adherence, Medication | Treatment Adherence | Familial Hypercholesterolemia | Motivational Interviewing | Adherence, Patient | Treatment Adherence and Compliance | Patient Compliance | Adherence | Hypercholesterolemia, Familial | Patient Adherence | Hypercholesterolemia, Autosomal Dominant and other conditions

Russian Federation
US Department of Veterans Affairs

Completed

Behavioral Insomnia Therapy in Primary Care

Insomnia | Primary Insomnia | Secondary Insomnia

United States
University of Utah
Evans Army Community Hospital

Completed

Two Contrasting Interventions for Sleep Management

Primary Insomnia | Secondary Insomnia

United States
University College Dublin
Irish Cancer Society; Big Health Inc.; myPatientSpace

Completed

The Menopause After Cancer Study (MACS)

Cancer | Insomnia | Menopause

Ireland
University of Washington

Unknown

Effects of Leader Sleep Improvement on Leadership

Chronic Insomnia | Insomnia, Primary
Jack Edinger, PhD
Merck Sharp & Dohme LLC

Completed

Impact of Hyperarousal on Simple and Complex Cognitive Task Performance Among Insomnia Sufferers

Insomnia | Primary Insomnia | Chronic Insomnia

United States
University of Pittsburgh

Completed

Exercise and Insomnia Study: The Effects of 1 Week of Exercise Training on Insomnia Severity (Insomni-Ex)

Insomnia Chronic | Insomnia, Primary

United States
University Hospital, Bordeaux

Completed

Self Help Program for Hypnotics Withdrawal in Insomniac Patients (PROPERSOM)

Insomnia

France
Roxane Laboratories

Completed

Bioequivalency Study of Zaleplon 10 mg Capsules Under Fasting Conditions

Short Term Treatment of Insomnia

United States
University of Surrey
H. Lundbeck A/S

Completed

Study to Investigate the Effects of Melatonin, Temazepam & Zolpidem on Sleep EEG in Men and Women

Insomnia

United Kingdom
University Hospital, Brest

Unknown

Stopping Cardiovascular Treatments and Mortality in a MICU (TRAM)

Cardiovascular Diseases | Critical Care | Outcome, Fatal | Medication

France
Aga Khan University

Completed

Outcome of Proximal Femur Replacement at a Tertiary Care Hospital

Outcome, Fatal
Eli Lilly and Company

Completed

An Efficacy Study of Compound LY2624803 in the Treatment of Patients With Chronic Insomnia (SLUMBER)

Primary Insomnia | Secondary Insomnia

United States
Alnylam Pharmaceuticals

Completed

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

ATTR Amyloidosis | Transthyretin (TTR)-Mediated Amyloidosis | Familial Amyloidotic Polyneuropathy (FAP) | Familial Amyloid Neuropathies

France, Germany, Portugal, United Kingdom, Sweden, Spain
University of Aarhus
TrygFonden, Denmark; Enversion A/S

Active, not recruiting

Determination of Optimal Sleep Treatment Elements - MOST (DOSE)

Insomnia Chronic

Denmark
Duke University

Completed

Sleep Device Testing

Insomnia Chronic

United States
Posit Science Corporation

Completed

STATE Trial: SusTained Attention Training to Enhance Sleep - Remote (STATE)

Insomnia Chronic

United States
University of Aarhus
TrygFonden, Denmark; Enversion A/S

Completed

Determination of Optimal Sleep Treatment Elements - Pilot (DOSE)

Insomnia Chronic

Denmark
Jun Song

Unknown

Experimental Research Center of China Academy of Chinese Medical Sciences

Insomnia Chronic

China
University of Manitoba

Completed

Efficacy of Sleeping Without Pills (SWOP), an Online Drug Tapering Program

Insomnia Chronic

Canada
University of Missouri-Columbia
University of Florida

Completed

Intraindividual Variability in Sleep and Cognitive Performance in Older Adults (REST)

Insomnia Chronic
Leiden University Medical Center
Jacobijn Gussekloo, Prof. dr.; Simon P. Mooijaart, Prof. dr.

Recruiting

Longevity Families of the Netherlands (LOF-NL)

Aging | Extreme Longevity | Longevity | Familial Longevity

Netherlands
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Enhancing Performance of Cognitive Behavioral Therapy for Insomnia With an Integrative Mobile Platform

Primary Insomnia | Depressive Disorders With Insomnia

Taiwan
Diakonhjemmet Hospital

Active, not recruiting

Cognitive Behavioral Therapy for Insomnia (CBTi) in Patients With Somatic Disease

Sleep Disorder | Insomnia | Sleep Initiation and Maintenance Disorders | Chronic Disease | Sleep Disturbance | Insomnia Chronic | Insomnia Due to Medical Condition | Insomnia, Psychophysiological

Norway
Hamisu Salihu

Completed

Preventing Fetal Body and Brain Size Reduction in Low-income Smoking Mothers: A Randomized Clinical Trial

Fetal Body Size | Fetal Brain Size

United States
Diakonhjemmet Hospital

Completed

Cognitive Behavioral Therapy for Insomnia (CBTi) in Patients With Mental Illness

Sleep Disorder | Insomnia | Sleep Initiation and Maintenance Disorders | Sleep Disturbance | Mental Illness | Depression, Anxiety | Insomnia Chronic | Psychological Disorder | Insomnia Due to Mental Disorder | Insomnia, Psychophysiological

Norway
National Yang Ming University
Bened Biomedical Co., Ltd.

Completed

The Effects of Lactobacillus Plantarum PS128 in Self-Reported Insomniacs

Insomnia

Taiwan
Shaare Zedek Medical Center

Unknown

Clown Doctors and a Sedative Premedicant for Children Undergoing Surgery

Insomnia

Israel
Boston University
National Institute of Neurological Disorders and Stroke (NINDS); Food and Drug...

Completed

The Effect of Diflunisal on Familial Amyloidosis

Familial Amyloid Polyneuropathy | Familial Amyloidosis

United States, Italy, Japan, Sweden, United Kingdom
Pfizer

Completed

The Effect Of Tafamidis For The Transthyretin Amyloid Polyneuropathy Patients With V30M Or Non-V30M Transthyretin

Transthyretin Familial Amyloid Polyneuropathy

Japan
University of Pennsylvania
Doris Duke Charitable Foundation

Completed

Effects of Insomnia Treatment on Metabolism in Patients With Depression

Depression | Insomnia | Depressive Symptoms | Insomnia Chronic | Insomnia, Primary

United States
CENTOGENE GmbH Rostock
Alnylam Pharmaceuticals

Recruiting

TRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive Subjects (TRAMmoniTTR)

Cardiomyopathies | Polyneuropathies | Transthyretin Amyloidosis | Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy

Germany, Austria, Switzerland
Regeneron Pharmaceuticals
Sanofi

Terminated

Long Term Safety Study of PRALUENT

Heterozygous Familial Hypercholesterolemia | Non-familial Hypercholesterolemia

United States, Bulgaria, Estonia, Russian Federation, South Africa, Ukraine
Merck Sharp & Dohme LLC

Terminated

A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158)

Hypercholesterolemia, Familial | Heterozygous Familial Hypercholesterolemia
Institut Investigacio Sanitaria Pere Virgili

Recruiting

Early Detection of Familial Hypercholesterolemia in Children (DECOPIN)

Familial Hypercholesterolemia | Familial Hypercholesterolemia - Homozygous | Familial Hypercholesterolemia - Heterozygous

Spain
Novartis Pharmaceuticals

Active, not recruiting

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia (ORION-13)

Familial Hypercholesterolemia - Homozygous

Greece, Lebanon, Turkey, France, Canada, Malaysia, Netherlands, United States
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of Acoramidis (AG10) in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
Overseas Pharmaceuticals, Ltd.
Guangzhou Kangqi Medical Technology Co., LTD

Not yet recruiting

Comparative Pharmacokinetic (PK) Study of Ibuprofen and Diphenhydramine Hydrochloride MR Tablets in Healthy Adults Under Fasting Condition

Pain | Insomnia

China
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy

United States
SOM Innovation Biotech SA
Hospital Vall d'Hebron

Completed

Study of SOM0226 in Familial Amyloid Polyneuropathy

Familial Amyloid Polyneuropathy (FAP)

Spain
Zhongnan Hospital

Unknown

A Pharmacokinetics Study of Daptomycin in Critically Ill Patients and Effects of Daptomycin on Kidney

Infection | Outcome, Fatal

China
University of Vermont

Withdrawn

Impact of Patient Education on Benzodiazepine Use in the Elderly

Insomnia | Anxiety
University of Tromso
University Hospital of North Norway; Diakonhjemmet Hospital

Not yet recruiting

Sleep Well Despite Persistent Pain Symptoms (Sleep-Well)

Pain, Chronic | Insomnia Chronic | Insomnia Due to Medical Condition

Norway
Marcello Arca
Pfizer; Göteborg University; University of Helsinki

Not yet recruiting

In Vivo Metabolism of apoB-containing Lipoproteins in ANGPTL3 Deficient Subjects

Familial Hypobetalipoproteinemia | Familial Hypobetalipoproteinemia - Heterozygous Form
Novartis Pharmaceuticals

Recruiting

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Adolescent ORION-16 or ORION-13 Studies (V-PEDS-OLE)

Heterozygous or Homozygous Familial Hypercholesterolemia

Netherlands, Israel, Hungary, Italy, Germany, Spain, France, Norway, South Africa, Turkey, United Kingdom, Canada, Switzerland, Brazil, Lebanon, Slovenia, United States, Russian Federation, Taiwan
Alnylam Pharmaceuticals

Completed

APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis

Amyloid Neuropathies | Amyloid Neuropathies, Familial | TTR-mediated Amyloidosis | Amyloidosis, Hereditary | Amyloidosis, Hereditary, Transthyretin-Related | Familial Amyloid Polyneuropathies

United States, Canada, Argentina, Australia, Bulgaria, Cyprus, Italy, Japan, Malaysia, Mexico, Netherlands, Portugal, Spain, Sweden, Germany, France, Brazil, Turkey, Korea, Republic of, Taiwan, United Kingdom
Intellia Therapeutics

Recruiting

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy | Wild-Type Transthyretin Cardiac Amyloidosis

United Kingdom, New Zealand, Sweden
Intellia Therapeutics

Active, not recruiting

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)

Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy | Wild-Type Transthyretin Cardiac Amyloidosis

France, United Kingdom, New Zealand, Sweden

Clinical Trials on Fatal Familial Insomnia

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