Clinical Trials on Fibrosis, Bone Marrow in France

Total 3137 results

Hoffmann-La Roche

Completed

A Phase 2 Study of RO7490677 In Participants With Myelofibrosis

Primary Myelofibrosis | Polycythemia Vera | Post-Essential Thrombocythemia Myelofibrosis

United States, Netherlands, Italy, United Kingdom, Canada, France, Germany, Israel
Groupe Francophone des Myelodysplasies
Merck Sharp & Dohme LLC

Terminated

Addition of Vorinostat to Azacitidine in Higher Risk MDS a Phase II add-on Study in Patients With Azacitidine Failure (GFM-AZA-VOR)

Myelodysplastic Syndrome

France
Central Hospital, Nancy, France
Inserm U954 - N-GERE (Nutrition, Genetics and Exposition to Environmental...

Unknown

High Risk Myelodysplasia Treated by Azacytidine : Genetic and Epigenetic (MYRAGE) (MYRAGE)

High-risk Myelodysplastic Syndromes With Excess Blasts

France
Rennes University Hospital
Novartis; Ministry of Health, France

Terminated

Effect of a Perioperative Oral Nutritional Supplementation on Patients Undergoing Hepatic Surgery for Liver Cancer (IMPACT)

Hepatocellular Carcinoma | Cirrhosis | Liver Cancer | Liver Fibrosis

France
Groupe Francophone des Myelodysplasies

Unknown

Darbepoetin Alpha in Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes

France
University Hospital, Grenoble

Completed

Flow Cytometric Analysis of Peripheral Blood Neutrophil Myeloperoxidase Expression and Myelodysplastic Syndromes (MPO-MDS-PILOT)

Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

France
Assistance Publique - Hôpitaux de Paris

Completed

Lumbar Spinal Fibrosis and TNF Alpha Inhibition

Post Operative Sciatica by Lumbar Spinal Fibrosis

France
AbbVie

Active, not recruiting

Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis (TRANSFORM-1)

Myelofibrosis (MF)

United States, Australia, Austria, Belgium, Bulgaria, Canada, Croatia, France, Germany, Greece, Israel, Italy, Japan, Korea, Republic of, Netherlands, New Zealand, Russian Federation, Serbia, South Africa, Spain, Sweden, Taiwan, Turkey and more
Biomatlante
Atlanstat

Unknown

Performance and Safety of the Resorbable Collagen Membrane "Ez Cure"

Periodontal Bone Loss | Alveolar Bone Loss | Oral Bone Defect | Maxillofacial Bone Defect

France
Hospices Civils de Lyon

Recruiting

Myocardial Fibrosis, Function and Aging (MARVEL)

Healthy

France
Versailles Hospital

Completed

A Prospective Randomized Phase II Study Evaluating the Monitoring of Imatinib Mesylate Plasmatic Through Level in Patients Newly Diagnosed With CP-CML (OPTIMIMATINIB)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

France
Physio-Assist
Icadom

Completed

Ancillary Home Airway Clearance in CF Patients ( HomeCareSIMEOX )

Pulmonary Cystic Fibrosis

France
Hospices Civils de Lyon

Unknown

Renal Allograft : Evaluation of Parenchymal Fibrosis by Elastography (GREFE)

Renal Transplant

France
European Society for Blood and Marrow Transplantation
Bristol-Myers Squibb

Terminated

Efficacy and Safety Study of Dasatinib in Patients With Chronic Myeloid Leukemia (Dasatinib)

Chronic Myeloid Leukemia

Switzerland, United Kingdom, France, Germany
Groupe Francophone des Myelodysplasies

Recruiting

A Trial Testing Early vs Late Onset of EPO Alfa Treatment in Lower Risk MDS (EPO-PRETAR)

Myelodysplastic Syndromes

France
Medtronic - MITG
Registrat-Mapi

Completed

Efficacity Assessment of PREVADH® in Adhesion Prevention in Gynaecologic Surgery

Fertility Disorders | Uterine Fibroids

France
Groupe Francophone des Myelodysplasies
Roche Pharma AG; Celgene Corporation

Completed

Azacitidine Combined to Epoetin Beta in International Prognostic Scoring System (IPSS) Low-risk and Intermediate-1 Myelodysplastic Syndrome (MDS) Patients, Resistant to Erythropoetin-stimulating Agents (ESA)

Myelodysplastic Syndromes

France
Assistance Publique - Hôpitaux de Paris

Completed

Prospective Study of Belated Pulmonary Complications Occurring in Children Treated With Allogeneic Hematopoietic Stem Cells. (RESPPEDHEM)

Bronchiolitis Obliterans | Chronic Respiratory Insufficiency | Bone Marrow Transplant Infection | Organizing Pneumonia | Pulmonary Cytolytic Thrombi

France
European Organisation for Research and Treatment...

Completed

Infliximab in Treating Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes

France, Belgium, Netherlands, Czech Republic, Italy, Germany
Johann Wolfgang Goethe University Hospital

Completed

Acoustic Radiation Force Impulse-Imaging in Comparison to Transient Elastography for Liver Fibrosis Staging in HCV

Chronic Hepatitis C

Netherlands, Germany, France
Hospices Civils de Lyon

Unknown

Genetics of the Combined Pulmonary Fibrosis and Emphysema Syndrome (GENES-SEF)

Emphysema | Pulmonary Fibrosis | Healthy Subjects | Combined Pulmonary Fibrosis and Emphysema Syndrome

France
Assistance Publique - Hôpitaux de Paris
Novartis; Association Rhumatisme et Travail

Completed

Genetic Study of Families Affected by Paget's Disease of Bone (PAGET)

Paget's Disease of Bone

France
Centre Hospitalier Universitaire, Amiens
Centre Henri Becquerel; Hôpital Jeanne de Flandre LIlle

Recruiting

Evaluation of Optical Genome Mapping in Phi Negative Myeloproliferative Neoplasia in the Detection of Acquired Cytogenetic Abnormalities (MYELOCARTOCH)

Myeloproliferative Neoplasm | Optical Genome Mapping | Cytogenetics | Clonality | Prognostic Stratification

France
Assistance Publique - Hôpitaux de Paris
Roche Pharma AG

Completed

Pilot Study of Pirfenidone in Pulmonary Fibrosis With Anti-myeloperoxydase Antibodies (PIRFENIVAS)

Pulmonary Fibrosis

France
University Hospital, Brest

Recruiting

AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms (AVAJAK)

Polycythemia Vera | Essential Thrombocythemia | High-risk Patients | Prefibrotic/Early Primary Myelofibrosis | JAK2 V617F

France
University Hospital, Bordeaux

Completed

Factors Influencing Volumetric MR-HIFU Ablation of Uterine Fibroids (PERAGUS)

Uterine Fibroid

France
University Hospital, Bordeaux

Completed

Evaluation of New Biomarkers of Thrombosis in Myeloproliferative Neoplasms (MPN-BIOCLOT)

Myeloproliferative Neoplasm

France
medac GmbH

Completed

Clinical Phase III Trial Treosulfan-based Conditioning Versus Reduced-intensity Conditioning (RIC)

Acute Myeloid Leukemia | Myelodysplastic Syndrome

Germany, Italy, Poland, France, Finland, Hungary
Gustave Roussy, Cancer Campus, Grand Paris
Ministry of Health, France

Completed

Curative Efficacy of Pravastatine in Patients Presented Delayed Cutaneous and Subcutaneous Radio-induced Fibrosis (PRAVACUR)

Fibrosis

France
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Active, not recruiting

An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib (FREEDOM2)

Primary Myelofibrosis | Myelofibrosis | Post-Polycythemia Vera

Australia, Austria, Belgium, China, Czechia, France, Germany, Hungary, Italy, Korea, Republic of, Netherlands, Poland, Russian Federation, Spain, Ireland, United Kingdom
Kartos Therapeutics, Inc.
Telios Pharma, Inc.

Recruiting

KRT-232 in Combination With TL-895 for the Treatment of R/R MF and KRT-232 for the Treatment of JAKi Intolerant MF

Primary Myelofibrosis | Myelofibrosis | Post-PV MF | Post-ET Myelofibrosis

United States, Italy, Serbia, Poland, France, Austria, Bulgaria, Germany, Hungary, Spain
Centre Hospitalier de Saint-Brieuc
Rennes University Hospital

Unknown

Use of a Connected Companion in Children With Cystic Fibrosis (COMPANION-CF)

Chronic Disease | Cystic Fibrosis in Children

France
CTI BioPharma

Completed

Phase 2 Study: An Open-Label, Randomized, Phase 2 Dose-Finding Study of Pacritinib in Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post- Essential Thrombocythemia Myelofibrosis Previously Treated With Ruxolitinib

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post- Essential Thrombocythemia Myelofibrosis

United States, Spain, United Kingdom, Hungary, Korea, Republic of, France, Italy, Sweden
Hospices Civils de Lyon

Unknown

Iron Metabolism in Cystic Fibrosis

Iron Metabolism, Cystic Fibrosis

France
Groupe Francophone des Myelodysplasies
Novartis; Neovii Biotech

Active, not recruiting

Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Myelodysplastic Syndrome Low Risk

MDS

France
Assistance Publique - Hôpitaux de Paris

Completed

Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in Children (MORPHAPAIN)

Pain | Long-bone Fractures

France
Groupe Francophone des Myelodysplasies

Completed

Treatment of Anemia With Epoetin Beta in Low Risk Myelodysplastic Syndrome (MDS) (EPO-QoL)

Myelodysplastic Syndromes

France
AbbVie

Active, not recruiting

Safety and Tolerability Study of Oral ABBV-744 Tablet Alone or in Combination With Oral Ruxolitinib Tablet or Oral Navitoclax Tablet in Adult Participants With Myelofibrosis

Myelofibrosis (MF)

United States, Argentina, Australia, Brazil, Bulgaria, Chile, Hungary, Israel, Italy, Japan, Spain, Sweden, Turkey, Korea, Republic of
Incyte Corporation

Completed

Ruxolitinib (INCB018424) in Participants With Primary Myelofibrosis (PMF), Post Essential Thrombocythemia-myelofibrosis and Post Polycythemia Vera-myelofibrosis (PPV-MF)

MPN (Myeloproliferative Neoplasms)

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Volatilomic Approaches for the Study of CFTR Modulators (VOLATIL-CF) (VOLATIL-CF)

Cystic Fibrosis

France
Sierra Oncology LLC - a GSK company

Completed

Momelotinib in Transfusion-Dependent Adults With Primary Myelofibrosis (PMF) or Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF)

Primary Myelofibrosis (PMF) | Post-polycythemia Vera (Post-PV) Myelofibrosis | Postessential Thrombocythemia (Post-ET) Myelofibrosis

United States, Canada
Incyte Corporation

Completed

Alternative Dosing Strategy of Ruxolitinib in Patients With Myelofibrosis

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post-Essential Thrombocythemia Myelofibrosis

United States
Incyte Corporation

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement - (FIGHT-203)

MPN (Myeloproliferative Neoplasms)

United States, France, United Kingdom, Spain, Canada, Japan, Germany, Switzerland, Belgium, Austria, Italy
Assistance Publique - Hôpitaux de Paris
Geistlich Pharma AG

Unknown

Interest of Bone Substitute Material in Immediate Complete Denture (PANORAMIX)

Bone | Alveolar Bone Loss | Bone Substitute | Denture Complete Immediate | Replacement Material

France
Onconova Therapeutics, Inc.

Completed

Oral Rigosertib in Low Risk MDS Patients Refractory to ESAs

Myelodysplastic Syndromes

United States, France, Germany
University Hospital, Montpellier

Terminated

Analysis T Cells Response for Identification of Aspergillus Bronchitis With Cystic Fibrosis Patients

Cystic Fibrosis Patient | Patient Without Treatment Against A.Fumigatus

France
Hospital de Clinicas de Porto Alegre

Enrolling by invitation

Safety and Feasibility of the Use of Natural Killer Cells in Patients With Chronic Myeloid Leukemia

Chronic Myeloid Leukemia

Brazil
Groupe Hospitalier Paris Saint Joseph

Terminated

Evaluation of a Fracture Liaison Service in the Osteoporosis Care

Osteoporotic Fractures

France
AbbVie

Active, not recruiting

Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis (TRANSFORM-2)

Myelofibrosis (MF)

United States, Australia, Austria, Belgium, Bulgaria, Canada, Croatia, Czechia, Denmark, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, New Zealand, Poland, Puerto Rico, Russian Federation, Serbia, South... and more
University Hospital, Lille

Terminated

Functional Outcomes of Knee Protheses for Malignant Tumours of Bone (ISOMUTAR)

Bone Cancer | Knee Disease

France

Clinical Trials on Fibrosis, Bone Marrow in France

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