Clinical Trials on Flaviviridae Infections

Total 56526 results

Abbott

Completed

Study in Healthy Adults to Evaluate Effect of Food on Pharmacokinetics, Safety and Tolerability of ABT-450 With Ritonavir

HCV Infection

United States
Gilead Sciences

Completed

Sofosbuvir (GS-7977) in Combination With PEG and Ribavirin for 12 Weeks in Treatment Experienced Subjects With Chronic HCV Infection Genotype 2 or 3

Hepatitis C

United States
National Institutes of Health Clinical Center (CC)

Completed

Natural History of West Nile Virus Infection

Encephalitis | Myelitis | West Nile Virus

United States
Imperial College London

Completed

Anticoagulation in Liver Fibrosis in Patients With Hepatitis C Virus Infection

Liver Fibrosis

United Kingdom
Emergent BioSolutions

Completed

Study in Healthy Volunteers Evaluating Safety and Pharmacokinetics of Zika Virus Immune Globulin (ZIKV-IG)

Zika Virus Infection | Zika Virus Disease

Canada
Institute of Tropical Medicine, Belgium

Completed

Persistence of Zika Virus in Semen After Acute Infection

Transmission | Zika Virus | Zika Virus Disease | Virus Shedding

Belgium
University of Pennsylvania
Merck Sharp & Dohme LLC

Completed

Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C (HD)

Hepatitis C | Hemodialysis | Nosocomial Infection

United States
RTI International
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Zika in Infants and Pregnancy (ZIP)

Zika Virus Disease (Disorder)

Colombia, Brazil, Guatemala, Nicaragua, Peru, Puerto Rico
Janssen Infectious Diseases BVBA

Completed

Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Participants With Genotype 1 Chronic Hepatitis C Virus Infection and Cirrhosis

Hepatitis C Virus Infection

United States, Canada
Gilead Sciences

Terminated

Study to Investigate Pharmacokinetics, Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX) Fixed Dose Combination (FDC) in Adolescents and Children With Chronic Hepatitis C Virus (HCV) Infection

Hepatitis C Virus Infection

Poland, Italy, United Kingdom
ZymoGenetics

Completed

Study of PEG-rIL-29 (or PEG-IFN Lambda) in Subjects With Chronic Hepatitis C Virus Infection

Hepatitis C, Chronic

United States, Canada
Janssen R&D Ireland

Completed

3-year Follow-up Study in Patients Previously Treated With TMC435-Containing Regimen for the Treatment of Hepatitis C Virus Infection

Hepatitis C

United States, Canada, France, Belgium, Germany, Russian Federation, Poland
Gilead Sciences

Completed

Sofosbuvir/Velpatasvir Fixed-Dose Combination in Adults With Chronic HCV Infection and Child-Pugh Class B Cirrhosis (ASTRAL-4)

Hepatitis C Virus Infection

United States, Puerto Rico
Universitair Ziekenhuis Brussel

Recruiting

Relinking Diagnosed But Untreated HCV Patients Back Into Care. (Relink)

Hepatitis C Virus Infection

Belgium
Rockefeller University
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Effects of Chronic Viral Infection on Immune Response to Zoster Vaccination

Hepatitis C

United States
Gilead Sciences

Completed

Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin in Participants With Chronic Genotype 1 HCV Who Participated in a Prior Gilead-Sponsored HCV Treatment Study

HCV Infection

United States, France, Australia, Puerto Rico, Spain
Gilead Sciences

Terminated

Efficacy and Safety of Ledipasvir/Sofosbuvir, With or Without Ribavirin, in HCV Infected Participants Who Have Failed Prior Treatment With Sofosbuvir-based Therapies

Hepatitis C Virus Infection

United States, Canada, Puerto Rico
Ain Shams University

Completed

Early Treatment of Recurrent HCV- Infection Post Liver Transplantation in the Era of DAAs

Liver Transplantation
Assiut University

Not yet recruiting

Alpha -1- Microglobulin (α1M) as an Early Biomarker in Renal Extrahepatic Manifestations of HCV-infection

HCV | Renal Injury
Bristol-Myers Squibb

Completed

Safety and Efficacy of Daclatasvir (BMS-790052) Plus Standard of Care (Pegylated-interferon Alpha and Ribavirin)

Hepatitis C Infection

United States, France
National Institutes of Health Clinical Center (CC)

Completed

Nucleic Acid Amplification Testing (NAT) of Blood Donors for HCV and HIV

HIV Infection | Hepatitis C

United States
Ain Shams University

Recruiting

Pharmacokinetics of Sofosbuvir/Daclatasvir in HCV-infected Lactating Women

Hepatitis C Virus Infection

Egypt
Foundation for Innovative New Diagnostics, Switzerland
Institute of Tropical Medicine, Belgium

Completed

Evaluation Study of HCV RDTs in Fresh Samples

Hepatitis C Virus Infection

Georgia, Cambodia
Beni-Suef University

Completed

Sofosbuvir/Pegylated-interferon Plus Ribavirin With HCV Genotype 4 (HCV)

Hepatitis C Virus Infection
Gilead Sciences

Completed

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Activity of GS-9450 in Subjects With Chronic HCV

HCV Infection

United States, Netherlands, Germany
Janssen R&D Ireland

Completed

A Study in Healthy Participants Investigating the Safety, Tolerability and Plasma Pharmacokinetics (PK) of Single Oral Doses of JNJ-47910382

Hepatitis C Virus Infection

Germany
Gilead Sciences

Completed

GS-5885, GS-9451, Tegobuvir and Ribavirin (RBV) in Interferon Ineligible or Intolerant Subjects With Chronic Genotype 1a or 1b Hepatitis C Virus (HCV) Infection

Chronic Genotype 1a or 1b HCV Infection

United States, Canada, Puerto Rico
Takeda

Completed

Safety, Immunogenicity, and Dose Ranging Study of Inactivated Zika Virus Vaccine in Healthy Participants

Flavivirus Infections | Healthy Participants | Virus, Zika | Zika Virus Disease

United States, Puerto Rico
Atea Pharmaceuticals, Inc.

Terminated

Study of AT-752 in Patients With Dengue Infection

Dengue Fever

Brazil, Colombia, Ecuador, India, Malaysia, Peru, Philippines, Taiwan, Thailand, Vietnam
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Determining Responses to Two Different Vaccines in HIV and HCV Infected Individuals

HIV Infections | Hepatitis C

United States, Puerto Rico
Gilead Sciences

Completed

Study to Investigate the Efficacy and Safety of Sofosbuvir/Velpatasvir (SOF/VEL) Fixed-Dose Combination (FDC) and Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX ) FDC for 12 Weeks in Adults With Chronic Hepatitis C Virus (HCV) Infection

Hepatitis C Virus Infection

Korea, Republic of
National Institutes of Health Clinical Center (CC)

Completed

Zika Virus and Related Arbovirus Infections in Deferred Blood Donors (ZVADD)

Dengue Virus | Zika Virus | Chikungunya Virus Infections

United States
Prof. Dr. med. Jens Reimer
Janssen-Cilag G.m.b.H

Unknown

Epidemiology of Hepatitis C Virus Infection Among Opioid Substituted Patients (ECHO)

Hepatitis C

Germany
Hospital Clinic of Barcelona
Schering-Plough

Completed

Pegylated Interferon and Ribavirin in Hepatitis C Virus Infection After Liver Transplantation.

Hepatitis C

Spain
Johns Hopkins University
AbbVie

Recruiting

Rapid HCV Treatment Access for Persons Who Use Drugs (RAPID-HCV)

Hepatitis C Virus Infection, Response to Therapy of

United States, Canada
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Monitoring SOF/VEL in Treatment Naïve, HCV Participants With Active Infection (MINMON)

Liver Diseases | Hepatitis C | HIV-1-infection

United States, Uganda, Brazil, Puerto Rico, South Africa, Thailand
Bristol-Myers Squibb

Completed

An Anti-viral Combination Study With Japanese Hepatitis C Infection (HCV) Subject

Hepatitis C Infection

Japan
ZymoGenetics
Bristol-Myers Squibb

Unknown

Efficacy and Safety Study of PEG-rIL-29 Plus Ribavirin to Treat Chronic Hepatitis C Virus Infection (EMERGE)

Hepatitis C, Chronic

Australia, France, Poland, United States, Spain, Germany, Romania, Canada, Austria, Italy, Puerto Rico
Merck Sharp & Dohme LLC

Withdrawn

Study to Evaluate Different Regimens of Vaniprevir (MK7009) for the Treatment of Chronic Genotype 1 Hepatitis C Virus Infection in Treatment-naive Patients (MK-7009-019)(WITHDRAWN)

Chronic Genotype 1 Hepatitis C Virus Infection
University Health Network, Toronto
Gilead Sciences

Active, not recruiting

Lung Transplant HCV, Pilot Study

Hepatitis C | Lung Transplant Infection

Canada
Hepa C

Completed

Effectiveness, Safety and Clinical Outcomes of Paritaprevir/Ombitasvir/r+Dasabuvir 8 Weeks (3D8)

Hepatitis C Infection

Spain
Gilead Sciences

Terminated

Efficacy and Safety Study of GS-9450 Treatment for 6 Months in Patients With Chronic Hepatitis C Virus Infection

HCV Infection

United States, United Kingdom, Germany, Canada, Puerto Rico, Poland
Kaohsiung Medical University Chung-Ho Memorial...

Active, not recruiting

Micro-elimination of Hepatitis C Virus Infection in Uremics

Hepatitis C

Taiwan
Assiut University

Completed

Prevalence of Hepatitis c Virus Infection Among Rheumatological Patients

Hepatitis C

Egypt
Hadassah Medical Organization

Unknown

Prediction of Response to Treatment of Patients With Chronic HCV Infection by Genetic Profile

Hepatitis C Virus Chronic Infection

Israel
Merck Sharp & Dohme LLC

Completed

A Phase 2b, Safety and Efficacy Study of Boceprevir in Patients Coinfected With HIV and Hepatitis C (P05411 AM4)

HIV Infections | Hepatitis C | HCV Infection
Rush University Medical Center
Merck Sharp & Dohme LLC; University of North Carolina, Chapel Hill; Ruth M. Rothstein...

Completed

Study on Immunopathogenesis in HIV and Hepatitis C Coinfection

Fibrosis | HIV Infection | Inflammation | Hepatitis C Infection

United States
Oregon Health and Science University

Recruiting

Immunogenicity of Yellow Fever Vaccine 17D in Adults With Prior 17D Vaccination

Yellow Fever | Immunization; Infection

United States
University of Heidelberg Medical Center
London School of Hygiene and Tropical Medicine; Institut National de la Santé... and other collaborators

Completed

ZIKAlliance Pregnant Women Cohort (ZIKAlliancePW)

Pregnancy Related | Zika Virus

Brazil, Bolivia, Colombia, Cuba, Guadeloupe, Mexico, Venezuela
Beni-Suef University

Completed

Ombitasvir /Paritaprevir/Ritonavir Plus Ribavirin on HCV GT4

Hepatitis C Virus Infection

Clinical Trials on Flaviviridae Infections

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