Clinical Trials on Flaviviridae Infections

Total 56694 results

University of Heidelberg Medical Center
University of Sao Paulo

Withdrawn

ZIKAlliance Natural History Study (ZIKAllianceNH)

Zika Virus Infection | Zika Virus

Brazil
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Unknown

Evaluation of Medical Conditions Associated With Zika Virus Infection in Managua, Nicaragua

Zika Virus

Nicaragua
Tychan Pte Ltd.
Duke-NUS Graduate Medical School; Singapore Clinical Research Institute

Withdrawn

Safety and Tolerability of an Antibody Against Zika Virus (Tyzivumab) in ZIKV Infected Patients

Treatment of Acute Zika Virus Infection

Singapore
Tychan Pte Ltd.
National University Hospital, Singapore; National University, Singapore; Duke-NUS... and other collaborators

Completed

Safety and Tolerability of an Antibody Against Zika Virus (Tyzivumab) in Humans

Treatment of Acute Zika Virus Infection

Singapore
Bharat Biotech International Limited

Completed

Safety and Immunogenicity of BBV121 (Zika)

Zika Virus Infection

India
InBios International, Inc.
Biomedical Advanced Research and Development Authority; Fast-Track Drugs &...

Completed

Evaluation of the Clinical Performance of the ZIKV Detect™ 2.0 IgM Capture ELISA

Zika Virus Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

ZIKA Vaccine in Naive Subjects

Zika Virus Infection

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Evaluation of Viral Replication by Tonate Virus (TONV) and Zika Virus (ZIKV), Within an ex Vivo Trophoblast and Placental Model (ZITOPEx)

Zika Virus Infection
ModernaTX, Inc.

Active, not recruiting

A Study of Zika Vaccine mRNA-1893 in Adult Participants Living in Endemic and Non-Endemic Flavivirus Areas

Zika Virus

Puerto Rico, United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Safety and Immunogenicity of the Live Attenuated Zika Vaccine rZIKV/D4Δ30-713 in Flavivirus-naïve Adults

Zika Virus

United States
Oswaldo Cruz Foundation
National Institute of Allergy and Infectious Diseases (NIAID); Wellcome Trust; Walter Reed Army Institute of Research (WRAIR) and other collaborators

Completed

Study on the Persistence of Zika Virus (ZIKV) in Body Fluids of Patients With ZIKV Infection in Brazil (ZikaBra)

Zika Virus

Brazil
Trinidad and Tobago IVF and Fertility Centre
Institute of Tropical Medicine, Belgium

Completed

Understanding Excretion and Infectivity of Zika Virus in Semen During and After Infection

Zika Virus

Trinidad and Tobago
Massachusetts General Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Adherence to Care for Children With Congenital Zika Virus Infection in Puerto Rico

Adherence, Patient | Zika Virus Infection

Puerto Rico
Mohamed Saad

Unknown

Role OF OCT-A TO Detect Possible Retinal Vascular Complications of Sofosbuvir in Patients With Hepatitis C

HCV Infection

Egypt
National Institute of Allergy and Infectious Diseases...

Completed

VRC 705: A Zika Virus DNA Vaccine in Healthy Adults and Adolescents (DNA)

RNA Virus Infections | Virus Diseases | Flavivirus Infections | Flaviviridae Infections | Zika Virus Infection | Zika Virus | Flaviviral Diseases

United States, Puerto Rico, Mexico, Brazil, Colombia, Costa Rica, Ecuador, Panama, Peru
National Institute of Allergy and Infectious Diseases...

Recruiting

Evaluation of Two Zika Viruses for Use in Controlled Human Infection Models (CHIM)

Zika Virus

United States
National Institute of Allergy and Infectious Diseases...

Completed

Phase I, Randomized, Double-blinded, Placebo-Controlled Dose De-escalation Study to Evaluate Safety and Immunogenicity of Alum Adjuvanted Zika Virus Purified Inactivated Vaccine (ZPIV) in Adults in a Flavivirus Endemic Area

Zika Virus Infection

Puerto Rico
Themis Bioscience GmbH

Completed

Zika-Vaccine Dose Finding Study Regarding Safety, Immunogenicity and Tolerability (V186-001)

Zika Virus

Austria
ModernaTX, Inc.
Biomedical Advanced Research and Development Authority

Completed

Safety, Tolerability, and Immunogenicity of Zika Vaccine mRNA-1893 in Healthy Flavivirus Seropositive and Seronegative Adults

Zika Virus

United States, Puerto Rico
ModernaTX, Inc.
Biomedical Advanced Research and Development Authority

Completed

Safety, Tolerability, and Immunogenicity of mRNA-1325 in Healthy Adult Subjects

Zika Virus

United States
Universidade Federal de Pernambuco

Unknown

Effect of a Posture Adapter for 12 to 24-month Children With Zyka Virus Syndrome

Zika Virus

Brazil
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Immunogenicity of a Zika Virus DNA Vaccine, VRC-ZKADNA085-00-VP, in Healthy Adults

Prevention of Zika Infection | Zika-Specific Immune Response

United States
Kathryn Stephenson
National Institute of Allergy and Infectious Diseases (NIAID); Walter Reed...

Completed

Zika Virus Purified Inactivated Vaccine (ZPIV) Accelerated Vaccination Schedule Study (Z001)

Zika

United States
Mennonite Christian Hospital

Unknown

Seroepidemiology of Japanese Encephalitis Virus Infection in Hualien, Taiwan

Japanese Encephalitis
Sunshine Lake Pharma Co., Ltd.

Completed

Phase 3 Study of Yimitasvir Phosphate Capsules

Chronic HCV Infection

China
University of British Columbia
Canadian Institutes of Health Research (CIHR)

Completed

Pender Assisted Therapy (PATh) - Prospective Study of the Treatment of HCV

Hepatitis C Virus Infection

Canada
National Institute of Allergy and Infectious Diseases...

Completed

VRC 320: A Phase I, Randomized Clinical Trial to Evaluate the Safety and Immunogenicity of a Zika Virus DNA Vaccine, VRC-ZKADNA090-00-VP, Administered Via Needle and Syringe or Needle-free Injector, PharmaJet, inHealthy Adults

Prevention of Zika Infection | Zika-Specific Immune Response

United States
University Hospital, Toulouse
Institut Pasteur; Centre Hospitalier Universitaire de Pointe-a-Pitre

Completed

Pilot Study to Detect Zika Virus in Sperm (ZIKSPERM)

Viruses

Guadeloupe
Valneva Austria GmbH
Emergent BioSolutions

Completed

Randomized, Placebo-controlled, Observer-blinded Phase 1 Safety and Immunogenicity Study of Inactivated Zika Virus Vaccine Candidate in Healthy Adults

Zika Virus Infection | Zika Virus

United States
Sunshine Lake Pharma Co., Ltd.

Recruiting

Antaitavir Hasophate Capsules Combined With Yiqibuvir Tablets in Treatment Adult Patients With Chronic Hepatitis C

Chronic HCV Infection

China
Themis Bioscience GmbH

Completed

Safety and Immunogenicity of a Novel Vaccine Formulation MV-ZIKA-RSP (V187-001) (MV-ZIKA-RSP)

Zika Virus Infection

Austria
Mayo Clinic
Hoffmann-La Roche

Completed

MMF Influence on HCV Viral Evolution After Liver Transplantation

Liver Transplantation | HCV Infection

United States
GeneOne Life Science, Inc.
Inovio Pharmaceuticals

Completed

Evaluation of Safety, Tolerability, and Immunogenicity Study of GLS-6150 in Healthy Volunteers and in Persons Previously Treated for Hepatitis C Virus Infection

HCV Infection

Korea, Republic of
Gilead Sciences

Completed

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination Administered in Patients Infected With Chronic Genotype 1 or 4 HCV for Use in the Peri-Operative Liver Transplantation Setting

Hepatitis C Virus Infection

United States
Sunshine Lake Pharma Co., Ltd.

Completed

Phase 2 Study of Yimitasvir Phosphate Capsules

Chronic HCV Infection

China
University Hospital, Strasbourg, France

Unknown

Study of the Role of Dendritic Cells in the Recurrence of Hepatitis C After Liver Transplantation. Analysis of Hepatitis C Virus (HCV) Quasispecies Evolution.

HCV Infection

France
Hoffmann-La Roche

Completed

Study of ANA773 in Healthy Volunteers and Patients With Hepatitis C Virus (HCV) to Assess Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD)

HCV Infection

Netherlands
ANRS, Emerging Infectious Diseases

Completed

A Community-based Intervention Among Active Drug Users in Montpellier (ICONE)

Drug Use | HCV Infection

France
Gilead Sciences

Completed

A Multiple Ascending Dose Study of GS 5885 in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C

HCV Infection

United States
Gilead Sciences

Completed

Efficacy and Safety Study of GS-9256 and GS-9190 Alone and in Combination With Ribavirin for 28 Days in Patients With Chronic Hepatitis C Virus Infection

HCV Infection

Germany, Belgium, United Kingdom, France
Bristol-Myers Squibb

Completed

Safety and Efficacy of Daclatasvir (BMS-790052) Plus Standard of Care (Pegylated-interferon Alpha-2b and Ribavirin) in Japanese Patients

Hepatitis C Infection

Japan
Children's National Research Institute
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Neurodevelopmental Outcomes in ZIKV-Exposed Children

Child Development | Congenital Zika Syndrome | Zika Virus | Congenital Infection

United States, Colombia
Scynexis, Inc.

Completed

Study of SCY-635, Pegasys and Copegus in Hepatitis C

Hepatitis C Infection

United States, Puerto Rico
Gilead Sciences
Merck Sharp & Dohme LLC

Completed

Use-Results Surveillance Study of Sovaldi® Plus Rebetol® in Japanese Patients With Chronic Genotype 2 Hepatitis C Virus Infection

Hepatitis C

Japan
Arrowhead Regional Medical Center

Terminated

Treating Hispanic Patients Diagnosed With Hepatitis C Using Boceprevir

Hepatitis C Infection

United States
Gilead Sciences

Completed

Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Adults With Chronic HCV Infection (ASTRAL-1)

Hepatitis C Virus Infection

United States, France, Canada, Germany, Puerto Rico, United Kingdom, Belgium, Italy, China
National Institute of Allergy and Infectious Diseases...

Completed

A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects.

Zika Virus Infection

United States
Sanofi Pasteur, a Sanofi Company

Completed

Zika Case Definition and Surveillance Study

Zika Virus Disease

Colombia, Honduras, Mexico, Puerto Rico
Hoffmann-La Roche

Completed

A Study of Balapiravir in Patients With Dengue Virus Infection

Dengue

Vietnam
Bristol-Myers Squibb

Completed

Safety and Efficacy of Daclatasvir (BMS-790052) Plus Standard of Care in Japanese Patients (Pegylated-interferon Alpha-2a and Ribavirin)

Hepatitis C Infection

Japan

Clinical Trials on Flaviviridae Infections

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