Clinical Trials on Frontotemporal Lobar Degeneration

Total 4310 results

Massachusetts General Hospital

Active, not recruiting

Exploring the Utility of [18F]3F4AP for Demyelination Imaging in Controls, Neurodegeneration and Traumatic Brian Injury

Brain Injuries, Traumatic | Alzheimer Disease | Demyelinating Disorder

United States
Regeneris Medical
Robert W. Alexander, MD, FICS; Global Alliance for Regenerative Medicine; Regeneris...

Unknown

Autologous Stem/Stromal Cells in Neurological Disorders and Disease (NDD)

Demyelinating Autoimmune Diseases, CNS | Dementia | Corticobasal Degeneration | Parkinson | Demyelinating Sensorimotor Neuropathy | Altered Behavior in Alzheimer Disease

United States
Afyon Kocatepe University Hospital

Completed

The Effect of Laser Treatment on Macular Pigment of Eye in Cases With Diabetes

Retinal Degeneration | Diabetic Retinopathy | Macula Abnormality | Laser Burn of Retina
Valérie Schuermans

Recruiting

Cervical Arthroplasty Cost Effectiveness Study (CACES) (CACES)

Cervical Disc Disease | Cervical Fusion | Fusion of Spine | Cervical Spondylosis | Cervical Disc Herniation | Myelopathy Cervical | Cervical Disc Degeneration | Radiculopathy, Cervical | Myelopathy, Compressive | Radiculopathy, Cervical Region | Radiculopathy; in Spondylosis | Radiculopathy; in Intervertebral... and other conditions

Netherlands
Second Affiliated Hospital, School of Medicine,...

Recruiting

Neuroimaging Changes in Hereditary Ataxia

Hereditary Ataxia

China
Masaryk University
Palacky University

Recruiting

Quantitative MR Parameters in Non-myelopathic Degenerative Cervical Spinal Cord Compression: a Longitudinal Study. (NOLOST)

Degenerative Cervical Spinal Myelopathy | Cervical Spinal Cord Compression

Czechia
Columbia University

Not yet recruiting

Impact of Exercise on Eyeblink Conditioning in Spinocerebellar Ataxias

Spinocerebellar Ataxias

United States
Institut National de la Santé Et de la Recherche...

Completed

RISCA : Prospective Study of Individuals at Risk for SCA1, SCA2, SCA3, SCA6, SCA7 (RISCA)

Spinocerebellar Ataxias

France
University of Florida
University of South Florida; National Institute of Neurological Disorders and...

Completed

Functional and Structural Imaging and Motor Control in Spinocerebellar Ataxia (SCA)

Spinocerebellar Ataxia

United States
Hospices Civils de Lyon

Not yet recruiting

Rehabilitation Program on Genetic and Degenerative Ataxia (RAPP)

Ataxia | Genetic Disease | Degenerative Disease

France
Karolinska Institutet
Karolinska University Hospital

Recruiting

Walking and Thinking - Brain Activity During Complex Walking in People With Multiple Sclerosis

Multiple Sclerosis | Aging | Gait Disorders, Neurologic | Neuro-Degenerative Disease

Sweden
Mayo Clinic

Withdrawn

Post-surgical Outcomes Measure Using the ERAS Protocol for Posterior Cervical Decompression and Fusion

Spinal Stenosis | Cervical Myelopathy | Degenerative Spinal Arthritis
University of Utah

Completed

High-Resolution Diffusion Tensor Imaging (DTI) of the Cervical Spinal Cord in the Setting of Spinal Cord Injury (SCI)

Spinal Cord Injury | Cervical Spondylosis With Myelopathy | Degenerative Disorder

United States
Changhua Christian Hospital

Recruiting

rTMS Improves Functions in Spinocerebellar Ataxia

Transcranial Magnetic Stimulation | Spinocerebellar Ataxias

Taiwan
Lawson Health Research Institute

Completed

Ocular Manifestations in Rheumatic Diseases

Uveitis | Macular Edema | Retinal Vein Occlusion | Retinitis | Orbital Diseases | Optic Neuritis | Keratoconjunctivitis Sicca | Conjunctivitis | Blindness | Xerophthalmia | Papilledema | Iridocyclitis | Retinal Artery Occlusion | Amaurosis Fugax | Scleritis | Eye Hemorrhage | Chorioretinitis | Choroid Hemorrhage
Yonsei University

Recruiting

Effect of High-intensity Statin With Ezetimibe COmbination theRapy Versus High-intensity sTatin Monotherapy After Percutaneous Coronary Intervention With Drug-eluting Stents; the ESCORT Trial

Coronary Artery Disease Requiring Coronary Revascularization With Newer Generation DES Implantation

Korea, Republic of
Zimmer Biomet

Recruiting

Comprehensive Segmental Revision System

Rheumatoid Arthritis | Trauma | Oncology | Degenerative Disease | Revision Surgery

Canada, Denmark, United Kingdom
Zimmer Biomet

Active, not recruiting

Anatomical Shoulder Domelock System Study

Arthritis, Rheumatoid | Avascular Necrosis | Arthritis, Degenerative | Revision Surgery | Conditions Consequent to Earlier Operations | Arthritis;Traumatic

Belgium, United Kingdom, Switzerland, Germany
Aesculap AG
Frictionless GmbH, Kiel

Completed

All Polyethylene Tibia-VEGA Kiel (APT-VEGA_KI)

Rheumatoid Arthritis | Post-traumatic; Arthrosis | Degenerative Osteoarthritis | Other Instability, Knee | Stiffness of Knee, Not Elsewhere Classified | Deformity of Knee Joint

Germany
Icahn School of Medicine at Mount Sinai

Withdrawn

Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery

Dysphagia | GERD | Degenerative Joint Disease

United States
Biohaven Pharmaceuticals, Inc.

Available

Expanded Access Protocol of Troriluzole in Patients With Spinocerebellar Ataxia (SCA)

Spinocerebellar Ataxias | SCA
Columbia University

Completed

Effect of Training on Brain Volume in Ataxia

Spinocerebellar Ataxias

United States
Barbara Borroni

Completed

Docosahexaenoic Acid (DHA) Replacement for Treatment in Spinocerebellar Ataxia 38 (SCA38DHA)

SCA38

Italy
Beth Israel Deaconess Medical Center
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Transcranial Magnetic Stimulation in Spino-Cerebellar Ataxia (TMS)

Spinocerebellar Ataxia

United States
Chang Gung University

Completed

Neuromuscular Electrical Stimulation on Median Nerve Facilitates Low Motor Cortex Excitability in Human With Spinocerebellar Ataxia

Spinocerebellar Ataxia

Taiwan
Mayo Clinic
National Institute on Aging (NIA)

Recruiting

A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's Disease

Healthy | Alzheimer Disease | Lewy Body Disease

United States
Editas Medicine, Inc.

Completed

Natural History Study of CEP290-Related Retinal Degeneration

Eye Diseases | Retinal Degeneration | Eye Diseases, Hereditary | Vision Disorders | Blindness | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

United States, Netherlands, France, Germany
Centre Hospitalier de PAU

Terminated

Neurodegeneration Markers and Neurological Course in Severe Covid-19 Infection (MARNEVO-Covid)

Encephalitis | COVID-19 Infection

France
Pixium Vision SA

Completed

Compensation for Blindness With the Intelligent Retinal Implant System (IRIS V2) in Patients With Retinal Dystrophy (IRIS 2)

Retinitis Pigmentosa | Choroideremia | Cone Rod Dystrophy

Austria, Spain, United Kingdom, France, Germany
Susan J. Hayflick
Oregon Health and Science University; Oregon Clinical and Translational Research...

Completed

Brain Perfusion in Pantothenate Kinase-associated Neurodegeneration (PKAN)

Pantothenate Kinase-associated Neurodegeneration (PKAN)

United States
Abbott Medical Devices

Active, not recruiting

The CONFIDENCE Registry

Severe Aortic Stenosis | Symptomatic Degenerative Aortic Stenosis

Spain, Italy, United Kingdom, Germany, Switzerland, Czechia, Australia, Belgium, Poland
Ege University

Completed

Regular Exercise Improves Physical Capacity and Promotes Neurotrophins in Patients With Multiple Sclerosis

Multiple Sclerosis | Neuro-Degenerative Disease | Exercise Intervention

Turkey
AlloSource

Completed

Study of Subtalar Arthrodesis Using AlloStem® Versus Autologous Bone Graft

Post-traumatic; Arthrosis | Degenerative Osteoarthritis | Rheumatoid Arthritis & Other Inflammatory Polyarthropathies | Rheumatoid Arthritis of Subtalar Joint

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia

Pathological Myopia

Germany, India, Japan, Turkey, Austria, Switzerland, Italy, Lithuania, Hungary, France, Slovakia, United Kingdom, Korea, Republic of, Portugal, Hong Kong, Canada, Singapore, Spain, Latvia, Poland
Chang Gung University

Recruiting

Electrical Stimulation Cycling Training Effects on SCA

Spinocerebellar Ataxia (SCA)

Taiwan
Mayo Clinic

Recruiting

Investigating the Genetic and Phenotypic Presentation of Ataxia and Nucleotide Repeat Diseases

Cerebellar Ataxia | Spinocerebellar Ataxias | Nucleotide Repeat Disease

United States
University of Cagliari
Angela Sanna; Micaela Porta; Paolo Tacconi; Chiara Pau

Completed

Cerebellar Transcranial Direct Current Stimulation in Spinocerebellar Ataxia 38

Spinocerebellar Ataxias

Italy
BioMimetic Therapeutics

Completed

Augment® Injectable Bone Graft Compared to Autologous Bone Graft as a Bone Regeneration Device in Hindfoot Fusions

Arthritis | Osteoarthritis | Rheumatoid Arthritis | Degenerative Joint Disease | Congenital Deformity

United States, Canada
Assistance Publique - Hôpitaux de Paris

Completed

Clinical Trial With Riluzole in Spinocerebellar Ataxia Type 2 (ATRIL) (ATRIL)

Spinocerebellar Ataxia Type 2

France
Brainsway

Completed

The Influence of Deep TMS on Cerebellar Signs in Patients With Machado Joseph Disease

Machado Joseph Disease (SCA3)

Israel
ProQR Therapeutics

Recruiting

An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene. (BRIGHTEN)

Eye Diseases | Neurologic Manifestations | Retinal Degeneration | Retinal Dystrophies | Sensation Disorders | Vision Disorders | Blindness | Leber Congenital Amaurosis | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

Belgium, Brazil, Canada, Germany, Italy, Netherlands, United Kingdom
Changhua Christian Hospital

Completed

Could Tai-chi Help Maintain Balance of Spinocerebellar Ataxia Patients

Spinocerebellar Ataxias | Tai Chi
Hasan Kalyoncu University

Completed

Functional Trunk Training in Ataxia Patients

Ataxia, Spinocerebellar | Ataxias, Hereditary

Turkey
Chang Gung University

Completed

The Investigation of the Pre-movement Facilitation of Agonist-antagonist Muscles and the Effect of the Feedforward Rehabilitation in Individuals With Hypermetria

Spinocerebellar Atrophy (SCA)

Taiwan
General Hospital of Chinese Armed Police Forces

Unknown

A New Method to Treat Hereditary Cerebellar Ataxia - Umbilical Cord Mesenchymal Stem Cells Transplantation (SCA)

Hereditary Cerebellar Ataxia.

China
Integrative Skin Science and Research

Recruiting

The Effects of Almond on Facial Skin Collagen and Wrinkles

Wrinkle | Pigmentation | Collagen Degeneration | Elastic Skin

United States
Istituto Auxologico Italiano

Recruiting

Multicenter Study on the Role of Neurodegeneration Biomarkers in Obstructive Sleep Apnea Syndrome With Residual Excessive Daytime Sleepiness. (EDS in OSA)

Sleep Apnea Syndromes

Italy
Neuromed IRCCS
University of Rome Tor Vergata

Not yet recruiting

Effects of Ozanimod on Immune-mediated Mechanisms of Neurodegeneration in Multiple Sclerosis - a Preclinical Study

Healthy | Neuromyelitis Optica | Relapsing-Remitting Multiple Sclerosis (RRMS)

Italy
Susan J. Hayflick
Oregon Health and Science University

Recruiting

NBIAready: Online Collection of Natural History Patient-reported Outcome Measures

Neurodegeneration With Brain Iron Accumulation (NBIA)

United States
University Hospital, Bordeaux
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Testing of NBIA Genes: Analysis of Genetic Heterogeneity and Validation of Mitochondrial Markers for Assessing Causality of Sequence Variants. (NBIA MITO)

Neurodegeneration With Brain Iron Accumulation (NBIA)

France

Clinical Trials on Frontotemporal Lobar Degeneration

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CROs in Israel

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