Clinical Trials on Functional Impairment in Germany

Total 301 results

University of Erlangen-Nürnberg Medical School

Completed

Neurocognitive Function After Therapy of OSAS (203_14_B)

Neurocognitive Function | OSAS

Germany
Novartis Pharmaceuticals

Completed

Pharmacokinetics of RLX030 in Subjects With Mild, Moderate and Severe Hepatic Impairment Compared to Healthy Subjects

Hepatic Impairment

Germany, Russian Federation
RWTH Aachen University

Unknown

Impact of Acute Cerebral Diseases on the Autonomous Nervous System: Progression and Correlation to Therapy and Outcome (Pupillometry)

Cerebral Aneurysm | Pupillary Function, Abnormal

Germany
Universitätsklinikum Hamburg-Eppendorf
Prostate Center North West Department of Urology and Pediatric Urology

Completed

Lung Function After Robot-assisted Radical Prostate Ectomy

Lung Function

Germany
Universitätsklinikum Hamburg-Eppendorf
European Union

Completed

Effects of Infra- and Ultrasound on the Brain

Depression | Sleep | Well-being | Cognitive Function | Ultrasound | Brain Function

Germany
Novartis Pharmaceuticals

Withdrawn

Systemic VEGF Protein Dynamics Following Intravitreal Injections of Ranibizumab Versus Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (TIDE DME)

Visual Impairment Due to Diabetic Macular Edema

Germany
Klinikum Ludwigshafen

Completed

Influence of of a Lipid Emulsion on Inflammatory Response and Hepatic Function

Inflammatory Response | Hepatic Function

Germany
Goethe University

Completed

Influence of Extracorporeal Circulation on Platelet Function of Patients Undergoing Cardiac Surgery

Acquired Platelet Function Disorder

Germany
University Hospital Schleswig-Holstein

Withdrawn

Confocal Laser Endomicroscopy, IBS and Stress

Irritable Bowel Syndrome

Germany
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Works in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function and How Cagrilintide is Absorbed and Used by the Body

Healthy Volunteers | Hepatic Impairment

Germany, Slovakia
Novartis Pharmaceuticals

Completed

Pharmacokinetic Study of BKM120 in Subjects With Hepatic Impairment

Hepatic Impairment

Germany, Russian Federation, Bulgaria
Janssen Infectious Diseases BVBA

Completed

A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment

Hepatic Impairment

Germany, Czech Republic
Heart Center Leipzig - University Hospital

Recruiting

Right VEntricular Contractile ReSERVE in Functional Tricuspid Regurgitation (RESERVE)

Functional Tricuspid Regurgitation

Germany
Charite University, Berlin, Germany
Berlin Institute of Health; Federal Agency for Disruptive Innovation - SPRIN-D

Completed

Evaluation of Safety of Contraloid Acetate in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Mild Cognitive Impairment Due to Alzheimer's Disease

Germany
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Pharmacokinetics of AFQ056 in Subjects With Hepatic Impairment Compared to Healthy Subjects

Hepatic Impairment

Germany, United States, Hungary
University Hospital, Saarland

Completed

Monocyte Subsets Altered by Anesthesia

General Anesthesia | Regional Anesthesia | Immune Function

Germany
Wuerzburg University Hospital

Withdrawn

Cognitive Ability Training for Seniors With Mild Cognitive Impairment (MICE)

Mild Cognitive Impairment

Germany
Merck KGaA, Darmstadt, Germany

Completed

Effect of Renal Impairment on Evobrutinib Pharmacokinetics (PK)

Renal Impairment

Germany
Charite University, Berlin, Germany
German Research Foundation

Completed

Impact of Transcranial Direct Current Stimulation on Language Functions in Mild Cognitive Impairment (STIMCI)

Mild Cognitive Impairment

Germany
Nycomed
NPS Pharma

Completed

Pharmacokinetics of 10 mg Teduglutide in Subjects With Renal Impairment Compared to Healthy Subjects With Normal Renal Function

Renal Impairment

Germany
AstraZeneca

Completed

Safety Study of AZD5672 in Renally Impaired Subjects

Renal Impairment

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ID-085 in People With Mild, Moderate, and Severe Kidney Disease

Renal Impairment

Germany
Charite University, Berlin, Germany
German Federal Ministry of Education and Research

Completed

Effects of Dietary Interventions on the Brain in Mild Cognitive Impairment (MCI)

Mild Cognitive Impairment

Germany
Polyphor Ltd.

Completed

Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment

Renal Impairment

Germany
Sanofi

Completed

Pharmacokinetic and Tolerability Study of 14 mg Single Dose of Teriflunomide in Subjects With Severe Renal Impairment

Renal Impairment

Germany
Wuerzburg University Hospital

Completed

Cognitive Ability Training in Seniors (CATS)

Mild Cognitive Impairment

Germany
H. Lundbeck A/S

Completed

Pharmacokinetic Properties of Nalmefene in Subjects With Renal Impairment and in Healthy Subjects

Renal Impairment

Germany
Galapagos NV

Completed

Study to Evaluate GLPG0634 in Subjects With Renal Impairment Compared to Healthy Subjects

Renal Impairment

Germany
University Hospital Schleswig-Holstein

Completed

Incidence and Prevention of Hypothermia in Newborns Bonding During Caesarean Section (THER5)

Hypothermia | Postoperative Shivering | Thermoregulation Impairment

Germany
Universität des Saarlandes
Geriatrische Rehaklinik

Completed

B-vitamins Treatment for Improvement of Cognitive Function

Cognitive Function | Metabolic Improvements

Germany
University of Rostock

Completed

Outcome of Patients After Total Knee Replacement: A Comparison of Femoral Nerve Block and Epidural Anesthesia

Mortality | Complications | Morbidity | Function

Germany
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
InQpharm Group

Completed

IQP-CL-101 in IBS Management

Irritable Bowel Syndrome

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Pharmacokinetics of ACT-1014-6470 in Subjects With Severe Renal Impairment Compared to Control Subjects

Healthy

Germany
Campus Bad Neustadt
Rhönklinikum AG

Completed

Geriatric Assessment and Outcome in Patients Undergoing Transcatheter Aortic Valve Replacement

Influence of Geriatric Functional State on the Outcome After TAVI | Possible Change in Geriatric Assessment After TAVI

Germany
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

Germany, Poland, Slovakia
University of Konstanz
University of Ulm

Completed

Sensory-cognitive and Physical Fitness Training in Mild Cognitive Impairment

Mild Cognitive Impairment (MCI) | Mild Alzheimer's Disease

Germany
Johann Wolfgang Goethe University Hospital

Completed

Effect of Exosomes Derived From Red Blood Cell Units on Platelet Function and Blood Coagulation

Platelet Function | Blood Coagulation

Germany
Idorsia Pharmaceuticals Ltd.

Completed

The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics

Healthy Subjects | Hepatic Impairment

Germany, Poland
Daacro
OOO MNPK BIOTIKI

Completed

Effects of Microencapsulated Sublingual Glycine (Bidicin) on Cognitive Performance in Healthy Men After an Acute Stressor

Healthy | Stress, Psychological | Cognitive Impairment

Germany
Janssen Pharmaceutica N.V., Belgium

Terminated

A Study to Evaluate the Effect of Renal Impairment on JNJ-64417184 and Its Two Minor Metabolites JNJ-68294291 and JNJ-65201526 in Adult Participants

Renal Impairment

Germany
A-Mansia Biotech S.A.

Completed

Study to Evaluate the Effect of Pasteurized Akkermansia Muciniphila (pAkk) on Complaints Related to IBS

Irritable Bowel Syndrome

Germany
Heinrich-Heine University, Duesseldorf

Completed

Influence of Tidal Volume on Postoperative Pulmonary Function (tidalvolume)

Pulmonary Function

Germany
Merck KGaA, Darmstadt, Germany

Completed

Pharmacokinetics in Subjects With Renal Impairment

Renal Impairment

Germany
H. Lundbeck A/S

Terminated

Pharmacokinetics of Lu AF35700 in Subjects With Renal Impairment

Renal Failure

Germany
University of Ulm
Ravensburger Spieleverlag GmbH (RSV), Germany

Completed

The Effect of Solving Jigsaw Puzzles on Visuospatial Cognition in Older Adults: Jigsaw Puzzles As Cognitive Enrichment (PACE)

Cognitive Impairment

Germany
Heinrich-Heine University, Duesseldorf

Completed

PASCAL vs. MitralClip for Mitral Valve Transchatheter Edge-to-Edge Repair

Mitral Regurgitation | Functional Mitral Regurgitation | Degenerative Mitral Valve Regurgitation

Germany
Universität Duisburg-Essen

Completed

The Effect of Hot Cataplasm With Caraway Oil in the Treatment of Irritable Bowel Syndrome (CarO)

Irritable Bowel Syndrome

Germany
Universität Duisburg-Essen

Completed

Yoga for Patients With Irritable Bowel Syndrome

Irritable Bowel Syndrome

Germany
UCB BIOSCIENCES GmbH

Completed

Study to Evaluate the Pharmacokinetics, Safety, Tolerability of Single Dose Lacosamide in Subjects With Renal Impairment Compared to Healthy Subjects

Healthy | Renal Impairment

Germany

Clinical Trials on Functional Impairment in Germany

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