Clinical Trials on Gastro Oesophageal Cancer

Total 55563 results

Dana-Farber Cancer Institute

Completed

FOLFOX +/- Ziv-Aflibercept for Esophageal and Gastric Cancer

Gastric Cancer | Esophageal Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Selinexor in Combination With Irinotecan in Adenocarcinoma of Stomach and Distal Esophagus

Gastric Cancer | Esophageal Cancer

United States
Hoffmann-La Roche
BioLineRx, Ltd.; Halozyme Therapeutics

Active, not recruiting

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma

United States, United Kingdom, Australia, Korea, Republic of, Taiwan, Israel, Spain
Dana-Farber Cancer Institute

Recruiting

Resilience and Equity in Aging, Cancer, and Health (REACH) (REACH)

Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Rectal Cancer | Colon Cancer | Gastrointestinal Cancer

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Evaluation of the Reliability of the Determination of MisMatch Repair Deficiency Status by Endoscopic Biopsies in Oesophagus and Gastric Adenocarcinoma. (BIOPSYGAST MMR)

Gastro-oesophageal Adenocarcinoma
University Hospital, Lille

Recruiting

Study of the Effect of the Time of Diagnosis (Antenatal vs. Postnatal) on the Post-traumatic Reactions of Parents of Children Undergoing Oesophageal Atresia Surgery " (DANAO)

Atresia, Esophageal

France
AstraZeneca

Completed

Prevalence of Gastroesophageal Reflux Disease (GERD) in Patients With Upper Gastrointestinal Tract Symptoms in Egypt (GERD Q NIS)

Patients With Upper Gastro-intestinal Symptoms

Egypt
howard safran
The Miriam Hospital; Rhode Island Hospital; Roger Williams Medical Center

Terminated

Chemotherapy for Patients With Gastroesophageal Cancers Who Have Progressed After One Prior Chemo Regimen

Gastric Cancer | Gastrooesophageal Cancer | Esophageal

United States
Fujian Cancer Hospital

Unknown

Clinical Trial to Compare Apatinib Plus Irinotecan Versus Single Irinotecan as Second-line Treatment in AGC or EGJA

Advanced Gastric Cancer Adenocarcinoma of Esophagogastric Junction

China
RenJi Hospital
Shanghai Tongji Hospital, Tongji University School of Medicine; Shanghai Pudong...

Completed

High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Gastroscopy Sedated by Propofol (HONCHO)

Hypoxia | Gastric Cancer | Adverse Event | Esophagus Cancer

China
Legend Biotech USA Inc

Recruiting

Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma

Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Gastroesophageal-junction Cancer

United States
Tularik

Suspended

Study of T900607-Sodium in Subjects With Previously Treated Gastric Cancer or Adenocarcinoma of the Esophagus

Gastric Cancer | Esophageal Neoplasms

United States
Karolinska University Hospital

Unknown

TaxXel: Taxotere and Xeloda in Esophageal Cancer (TaxXel)

Cancer of the Esophagus | Gastric Cardia Carcinoma

Norway, Sweden
Uriach Consumer Healthcare

Recruiting

Efficacy and Speed of Action of a Product to Control Gastric Hydration and Gastroesophageal Reflux (AQUAA)

Oesophageal Reflux | Gastric Reflux | Hyperactivity; Stomach

Spain
McGuire Research Institute
Hunter Holmes McGuire VA Medical Center

Unknown

Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux Disease (GERD)

Gastro Esophageal Reflux | Barrett Esophagus | Erosive Esophagitis

United States
Asian Institute of Gastroenterology, India

Recruiting

SAFETY AND EFFICACY OF ENDOSCOPIC CONVENTIONAL CYANOACRYLATE GLUE VS EUS-GUIDED COIL PLUS CYANOACRYLATE TECHNIQUE IN THE TREATMENT OF GASTRIC VARICES: A RANDOMIZED CONTROLLED TRIAL (GLUE)

Glue; Dependence

India
Nanchong Central Hospital

Recruiting

Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer

Gastric Cancer | Gastroesophageal Reflux Disease | Proximal Gastric Adenocarcinoma

China
NYU Langone Health

Terminated

Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers

Gastric Cancer | Esophageal Cancer | Gastric Adenocarcinoma

United States
Lipomedix Pharmaceuticals Inc.

Terminated

Assessment of Safety and Therapeutic Efficacy of Promitil in Combination With Folfox in Patients With GI Malignancies

Cancer | Gastro-Intestinal Intraepithelial Neoplasia

Israel
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Avelumab in Third-Line Gastric Cancer (JAVELIN Gastric 300)

Unresectable, Recurrent, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma | Gastric Cancer Third Line

Spain, Italy, Australia, Korea, Republic of, Belgium, France, Poland, United States, Czechia, Germany
Assiut University

Not yet recruiting

Endoscopic Ultrasound-guided Coil With Cyanoacrylate Injection Versus Balloon-Occluded Retrograde Transvenous Obliteration in Managing Patients With Gastric Varices

Gastric Varix
Aduro Biotech, Inc.
Merck Sharp & Dohme LLC

Terminated

Safety and Efficacy of CRS-207 With Pembrolizumab in Gastric, Gastroesophageal Junction or Esophageal Cancers

Gastric Adenocarcinoma | Esophageal Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

United States
Fudan University

Recruiting

Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer (Miracle-G)

Adenocarcinoma | Metastatic Cancer | Metastatic Gastric Cancer | Gastroesophageal Junction Adenocarcinoma | Oligometastatic Disease | Stomach Neoplasm | Adenocarcinoma of the Stomach | Gastroesophageal-junction Cancer | Metastatic Adenocarcinoma

China
Mahidol University

Recruiting

The Validation and Efficacy of Varix Trainer as a Training Device Esophagogastroduodenoscopy (a Multicenter Study)

Gastric Varix

Thailand
Mansoura University

Unknown

EUS-guided Obturation of High Risk Gastric Varices Versus Standard Endoscopic Treatment

Gastric Varix

Egypt
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC; Genentech, Inc.

Recruiting

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

Esophageal Cancer | Gastric Adenocarcinoma | HER2 Gene Mutation

United States
R. van Hillegersberg

Completed

Safety and Feasibility of TachoSil®: Application on Esophageal Anastomoses (SAFE-T)

Gastric Disease | Esophageal Disease

Netherlands
National Cancer Institute (NCI)

Recruiting

Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer

Gastric Adenocarcinoma | Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Gastroesophageal Junction Adenocarcinoma | Clinical Stage I Gastric Cancer AJCC v8 | Clinical Stage II Gastric Cancer AJCC v8 | Clinical Stage IVA Gastric... and other conditions

United States
University of Luebeck
Dr.Ahmad Keelani

Not yet recruiting

PrOgnosis Following Esophageal fisTula formaTion in Pts Undergoing cathetER Ablation for AF Study (POTTER)

Atrial Fibrillation | Catheter Ablation | PVI | Atrio-Oesophageal Fistula
Surgical Outcomes Research Centre (SOuRCe)

Recruiting

PRIORITY-CONNECT 2 Pilot Trial

Gastric Cancer | Colorectal Cancer | Pancreas Cancer | Liver Cancer | Oesophageal Cancer

Australia
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Recruiting

A Study of Trastuzumab DeRuxtecan for Patients With Advanced HER2-pOsitive GaStric or GastroesoPhageal Junction AdEnocarcinoma Who Have Received a PrIor Trastuzumab-based Regimen Accompanied by a Disease RegistrY of Patients Treated With Conventional Therapies (PROSPERITY)

HER2-positive Advanced Gastric Cancer | HER2-positive Gastroesophageal Junction Adenocarcinoma

Austria, Belgium, Germany, Italy
Baxter Healthcare Corporation

Completed

Efficacy and Safety of Endoscopic Injection of Fibrin Sealant Versus Endoscopic Ligature for Bleeding Esophageal Varices

Esophageal and/or Gastric Varices

Germany
Toray Industries, Inc

Recruiting

A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer

Gastric Cancer | Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

Korea, Republic of, United States, Japan
Phathom Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease

Heartburn | Non-Erosive Gastro-Esophageal Reflux Disease

United States
Assistance Publique Hopitaux De Marseille

Unknown

Correlation Between Clinical Signs and High-resolution Manometry Data in Children

Oesophageal Motility Disorder

France
Qilu Hospital of Shandong University

Enrolling by invitation

Effect of Re-education on Rebleeding Rate After Endoscopic Treatment in Liver Cirrhosis

Liver Cirrhosis | Bleeding | Gastric Variceal Bleeding | Esophageal Varices Bleeding

China
National Cancer Institute (NCI)

Active, not recruiting

Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction Cancer

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States
Cancer Research UK

Unknown

Study of Blood and Tissue Samples From Patients With Stomach Cancer, Esophageal Cancer, or Gastroesophageal Junction Cancer

Gastric Cancer | Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United Kingdom
Hospital Universitario La Fe

Enrolling by invitation

Predictive Model to Early Diagnosis of Anastomotic Leak After Esophagectomy and Gastrectomy. (PROFUGO)

Gastric Cancer | Complication | Esophagus Cancer | Leak, Anastomotic

Spain
University of Chicago

Suspended

Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy

Gastric Cancers

United States
Trans Tasman Radiation Oncology Group
National Health and Medical Research Council, Australia; Canadian Cancer Trials...

Completed

Advanced Oesophageal Cancer Study to Compare Quality of Life and Palliation of Dysphagia.

Esophagus Cancer

Australia, Canada, New Zealand, United Kingdom
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer

Gastric Cancer | Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United States
Phathom Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo for Relief of Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease (NERD)

Heartburn | Non-Erosive Gastro-Esophageal Reflux Disease

United States
Evangelic Hospital Kalk Cologne

Completed

Important Correlation Between Anxiety and Reflux Symptoms in Patients With Gastroesophageal Reflux Disease

Anxiety Disorders | GERD - Gastro-Esophageal Reflux Disease

Germany
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

SHR-A1811 for Subjects With Her2-positive Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on or After First-line Anti-HER2 Therapy-containing Regimen

HER2-positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

China
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

Study of SHR-8068 Combined With Adebrelimab and Platinum-containing Chemotherapy in the Treatment of Advanced Gastric and Esophageal Cancer

Advanced Gastric Adenocarcinoma and Esophageal Squamous Cell Carcinoma

China
National Cancer Institute (NCI)
NRG Oncology

Completed

Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer

Esophageal Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma | Stage IIA Esophageal Cancer AJCC v7 | Stage IIB Esophageal Cancer AJCC v7 | Stage IIIA Esophageal Cancer AJCC v7 | Stage IIIB Esophageal Cancer AJCC v7 | Stage IB Esophageal Cancer AJCC v7

United States
Peter MacCallum Cancer Centre, Australia

Terminated

A Study of APR-246 in Oesophageal Cancer (APROC)

Oesophageal Carcinoma

Australia
Singlera Genomics Inc.
Fudan University; Shanghai Zhongshan Hospital; Shanghai Public Health Clinical... and other collaborators

Completed

Establishment of Molecular Classification Models for Early Diagnosis of Digestive System Cancers

Hepatocellular Carcinoma | Colorectal Cancer | Esophageal Cancer | Gastric (Stomach) Cancer

China
Centre Hospitalier de la côte Basque

Recruiting

Quality of Life of Patients Over 75 Yars Undergoing Palliative Chemotherapy (EQLVCPAL)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Oesophageal Cancer | Hepatic Cancer | Biliary Cancer

France

Clinical Trials on Gastro Oesophageal Cancer

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