Clinical Trials on Gastrointestinal Failure in New Zealand

Total 3596 results

Alizyme

Terminated

Long-Term Safety of Renzapride in Women With Constipation-Predominant Irritable Bowel Syndrome (IBS-C)

Constipation-Predominant Irritable Bowel Syndrome

United States
Wake Forest University Health Sciences
University of Alabama at Birmingham

Recruiting

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer (M&M)

Colorectal Cancer | Sarcopenia

United States
Ardelyx

Completed

A Study to Evaluate the Safety and Efficacy of RDX5791 for the Treatment of Constipation Predominant Irritable Bowel Syndrome (IBS-C)

Constipation Predominant Irritable Bowel Syndrome

United States
University of Pennsylvania
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Gilead...

Recruiting

A Trial of Transplanting Hepatitis C Kidneys Into Hepatitis C-Negative Kidney Recipients (THINKER-NEXT)

End Stage Renal Disease

United States
Incara Pharmaceuticals

Completed

Safety and Efficacy of OP2000 (Deligoparin) in the Treatment of Active Ulcerative Colitis

Ulcerative Colitis

United States
Bausch Health Americas, Inc.

Completed

Efficacy and Safety of Budesonide Foam for Participants With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis

Proctitis | Proctosigmoiditis

United States
Bridge Biotherapeutics, Inc.
Covance

Completed

Efficacy and Safety of Orally Administered BBT-401-1S in Subjects With Ulcerative Colitis

Ulcerative Colitis

United States, Korea, Republic of, Poland, Ukraine
Bausch Health Americas, Inc.

Completed

The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy

Hepatic Encephalopathy | Cirrhosis

United States
AstraZeneca

Completed

Study of Esomeprazole 20 mg or 40 mg vs Placebo Effectiveness on the Occurrence of Peptic Ulcers in Subjects on Low Dose Acetylsalicylic Acid (LDA) (Oberon)

Gastric Ulcer | Duodenal Ulcer

United States, Bulgaria, Czech Republic, Korea, Republic of, Russian Federation, South Africa, Philippines, Poland, Romania, Finland, Norway, Canada, Mexico, Argentina, Australia, Germany, Portugal, Slovakia, Thailand, Indonesia
Pfizer

Terminated

Efficacy, Safety and Tolerability of PF-06687234 as Add-on Therapy to Infliximab in Active UC Subjects Not in Remission.

Ulcerative Colitis

United States, Australia, Italy, Korea, Republic of, Belgium, Israel, Turkey, Saudi Arabia, Germany, Serbia
Takeda

Completed

Efficacy and Safety of Dexlansoprazole Modified Release Formulation to Treat Heartburn

Gastroesophageal Reflux Disease

United States
Amgen
Zai Lab (China only)

Recruiting

Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression (FORTITUDE-101)

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Canada, Japan, United States, Korea, Republic of, China, Italy, Australia, Sweden, Spain, Taiwan, France, Belgium, Denmark, Thailand, Turkey, Czechia, Bulgaria, Brazil, Norway, Mexico, Poland, Estonia, Israel, Greece, Romania, Chile, Peru, Po... and more
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

Colorectal Cancer | Anal Cancer | Drug/Agent Toxicity by Tissue/Organ | Radiation Enteritis

United States
Takeda

Completed

A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn

Gastroesophageal Reflux

United States
AstraZeneca

Terminated

Evaluation of Efficacy and Safety of Brazikumab (MEDI2070) in Participants With Active, Moderate to Severe Crohn's Disease

Crohn's Disease

United States, France, Italy, Belgium, Australia, Canada, Hungary, Russian Federation, Spain, Germany, Netherlands, Israel
Saint Luke's Health System
AstraZeneca; George Clinical Pty Ltd; Saint Luke's Hospital of Kansas City

Completed

Dapagliflozin in Respiratory Failure in Patients With COVID-19 (DARE-19)

COVID-19

United States, Brazil, Argentina, India, Canada, Mexico, United Kingdom
Ole Frobert, MD, PhD
Uppsala University; Sanofi Pasteur, a Sanofi Company; Swedish Heart Lung Foundation and other collaborators

Completed

Study on the Effect of Influenza Vaccination After Heart Attack on Future Cardiovascular Prognosis (IAMI)

Myocardial Infarction | Heart Failure | Stroke | Influenza, Human | Influenza Vaccines

Denmark, United Kingdom, Sweden, Australia, Bangladesh, Czechia, Latvia, Norway
AstraZeneca
Parexel

Recruiting

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2 (Re-PHIRE)

Heart Failure | Pulmonary Hypertension (World Health Organization Group 2)

Netherlands, Spain, Japan, United States, Germany, Austria, China, Italy, Sweden, United Kingdom, Poland, Czechia, Denmark, Canada
OncoC4, Inc.
Avance Clinical; OncoC4 AU Pty Ltd

Recruiting

Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors (PRESERVE-009)

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Fallopian Tube Cancer | Non Small Cell Lung Cancer | Bile Duct Cancer | Bladder Cancer | Endometrial Cancer | Head and Neck Squamous Cell Carcinoma | Anal Cancer | Primary Peritoneal... and other conditions

Australia
Bristol-Myers Squibb

Recruiting

An Open-label Study of Ozanimod in Moderate to Severe Ulcerative Colitis in Clinical Practice

Colitis, Ulcerative

United States, United Kingdom
Roswell Park Cancer Institute

Active, not recruiting

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

Acute Myeloid Leukemia | Polycythemia Vera | Myelofibrosis | Chronic Myelomonocytic Leukemia | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Secondary Acute Myeloid Leukemia | Sickle Cell Disease | Myelodysplastic Syndrome | Plasma Cell Myeloma | Chronic Granulomatous... and other conditions

United States
Eisai Inc.

Completed

Comparing the Efficacy, Safety, and Tolerability of Rabeprazole ER 50 mg With Placebo in Subjects With Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroesophageal Reflux Disease (sGERD)

United States
Novartis Pharmaceuticals

Completed

Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM) (TRANSFORM)

Hemodialysis | Renal Replacement Therapy | End Stage Renal Disease (ESRD) | Renal Transplantation | Chronic Kidney Disease (CKD)

Germany, United States, Belgium, Italy, Spain, Croatia, Taiwan, Australia, Austria, Greece, Korea, Republic of, Lebanon, Czechia, Israel, Netherlands, Slovenia, Switzerland, Thailand, Norway, Turkey, Sweden, Argentina, Brazil, Japan, Se... and more
Wyeth is now a wholly owned subsidiary of Pfizer
Nycomed

Completed

Study Evaluating Pantoprazole in Children With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux

United States, Canada
Reistone Biopharma Company Limited

Recruiting

A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

China, United States, Georgia, Poland, Ukraine
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Completed

A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis (VOYAGE)

Eosinophilic Esophagitis

United States, Spain, Switzerland, Australia, Belgium, Netherlands, Canada, Germany
Respicardia, Inc.

Completed

Respicardia, Inc. Pivotal Trial of the remedē System

Heart Failure | Sleep Disordered Breathing | Sleep Apnea, Central

United States, Poland, Germany
Boston Pharmaceuticals

Completed

Study to Evaluate the Efficacy, Safety, and Tolerability of BOS-589 in the Treatment of Patients With Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)

Diarrhea-predominant Irritable Bowel Syndrome

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Recruiting

Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Sarcoma | Lymphoma | Leukemia | Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Clinical Stage III Cutaneous Melanoma AJCC v8 | Thyroid Gland Carcinoma | Clinical... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

HIV Infection | Anal Squamous Cell Carcinoma | Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | AIDS-Related Anal Carcinoma | Rectal Squamous Cell Carcinoma | Stage I Anal Cancer AJCC... and other conditions

United States
Shire

Completed

An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE) (ORBIT2)

Eosinophilic Esophagitis (EoE)

United States
Emory University
National Institute of Nursing Research (NINR)

Active, not recruiting

An Effectiveness-Implementation Trial of SPIRIT in ESRD

End Stage Renal Disease

United States
AbbVie

Recruiting

Study of ABBV-668 Oral Capsules to Assess Adverse Events and Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Belgium, France, Poland
Facet Biotech
PDL BioPharma, Inc.

Terminated

Study of Visilizumab Versus Placebo in Subjects With Intravenous Steroid-refractory Ulcerative Colitis Previously Responsive in a Visilizumab Study

Ulcerative Colitis

Belgium, France, United States, Italy, Canada, Czech Republic, Norway, Israel, Austria, Croatia, Australia, Hungary, Ukraine, Netherlands, Germany
Bausch Health Americas, Inc.

Completed

Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain

Constipation

United States
Regeneron Pharmaceuticals
Sanofi

Active, not recruiting

Study to Investigate the Efficacy and Safety of Dupilumab in Pediatric Patients With Active Eosinophilic Esophagitis (EoE) (EoE KIDS)

Eosinophilic Esophagitis (EoE)

United States, Canada
Shire

Completed

A Study in Adolescents and Adults With Eosinophilic Esophagitis (EoE) Measuring Histologic Response and Determine if Reduction in Dysphagia is Achieved

Eosinophilic Esophagitis (EoE)

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Docetaxel, Oxaliplatin, Capecitabine, Fluorouracil, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

Gastric Cancer | Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United States
Shire

Completed

Short Bowel Syndrome Research Study for Children Up To 17 Years of Age on Parenteral Nutrition

Short Bowel Syndrome

United States, Canada, Finland, Belgium, Italy, United Kingdom, Germany
Novartis

Completed

Efficacy, Safety and Tolerability of DNK333 (25 mg Bid) in Women With Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)

Irritable Bowel Syndrome With Diarrhea (IBS-D)

United States, Canada
Takeda

Completed

Determination of the Minimal Clinically Important Difference After Treatment With Pantoprazole in Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-340)

Gastroesophageal Reflux

United States
Eisai Inc.

Completed

Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)

Canada, Chile, Hungary, Bulgaria, Estonia, Latvia, United States, Croatia, Australia, India, Argentina, France, Germany
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

Colitis Ulcerative

Argentina, Korea, Republic of, Mexico, United States, Canada, Chile, Japan, Puerto Rico, South Africa, Taiwan, Turkey
Bausch Health Americas, Inc.

Completed

Randomized Placebo-Controlled Trial of Budesonide Multi-Matrix System (MMX®) 9 Milligrams (mg) in Participants With Ulcerative Colitis Currently on a 5-Aminosalicylic Acid (5-ASA)

Ulcerative Colitis

United States, Bulgaria, Canada, Czechia, Estonia, Hungary, Latvia, Lithuania, Poland, Russian Federation, Ukraine
Motus Therapeutics, Inc.

Completed

Phase 2 Study to Evaluate Safety & Efficacy of RM-131 Administered to Patients With Diabetic Gastroparesis

Diabetes Mellitus | Gastroparesis | Diabetes Mellitus Complications

United States
Children's Hospital of Philadelphia
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Active, not recruiting

VIRTUUS Children's Study (VIRTUUS)

End Stage Renal Disease | Nephropathy | Renal Transplant Rejection | Pediatric Kidney Disease | BK Virus (Nephropathy) | Antibody-mediated Rejection | Acute Cellular Graft Rejection

United States, Canada
Ironwood Pharmaceuticals, Inc.
Forest Laboratories

Completed

An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation

Irritable Bowel Syndrome With Constipation | Chronic Constipation

United States
AstraZeneca

Terminated

A Study of Benralizumab in Patients With Eosinophilic Esophagitis (MESSINA)

Eosinophilic Esophagitis

United States, Italy, Spain, Canada, Poland, Germany, Japan, Netherlands, France, Israel, Russian Federation, United Kingdom
Abbott

Completed

Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Acute Ulcerative Colitis

Ulcerative Colitis

United States, Austria, Belgium, Canada, Czech Republic, Germany, Hungary, Italy, Netherlands, Poland, Puerto Rico, Slovakia, Sweden
VA Office of Research and Development

Completed

Transfusion Trigger After Operations in High Cardiac Risk Patients (TOP)

Myocardial Infarction | Acute Renal Failure | Coronary Revascularization

United States

Clinical Trials on Gastrointestinal Failure in New Zealand

Sponsors and Collaborators

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CROs in Cote d'Ivoire

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