Clinical Trials on Gastrointestinal Discomfort

Total 23262 results

University Hospital, Bordeaux

Completed

A New Membrane Obturator Prothesis Concept for Soft Palate Defects (VELOMEMBRANE)

Deglutition Disorders | Speech Disorders | Mouth Neoplasms | Velopharyngeal Insufficiency

France
Eric Schwenk

Completed

Assessing Gastric Motility and Distention in Postoperative Gastrointestinal Surgery Using Bedside Gastric Ultrasound: Predicting Risk of Aspiration Pneumonia, Ileus, Return of Bowel Function

Postoperative Complications | Postoperative Nausea and Vomiting | Postoperative Nausea | Postoperative Vomiting | Postoperative Ileus | Aspiration Vomitus

United States
University of Oklahoma
OU Medical Center

Completed

Compassionate Use of Omegaven in Children

Infant, Premature, Diseases | Cholestasis | Gastroschisis | Intestinal Atresia | Short Bowel Syndrome | Cholestasis of Parenteral Nutrition | Total Parenteral Nutrition-induced Cholestasis

United States
Rennes University Hospital

Completed

Ultrasound TFP (Transversalis Fascia Plane) for Analgesia After Iliac Crest Bone Graft Harvest (TFP)

Patients Scheduled for Iliac Crest Bone Graft Harvest During Upper or Lower Limb Surgery

France
Diakonhjemmet Hospital
South-Eastern Norway Regional Health Authority

Completed

The NOR-SWITCH Study (NOR-SWITCH)

Rheumatoid Arthritis | Crohn's Disease | Ulcerative Colitis | Psoriatic Arthritis | Spondyloarthritis | Psoriasis Chronic

Norway
Swiss Tropical & Public Health Institute
Institute of Tropical Medicine, Belgium; B.P. Koirala Institute of Health Sciences and other collaborators

Completed

Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders (NIDIAGDigest)

Shigellosis | Schistosomiasis | Strongyloidiasis | Dientamoebiasis | Giardiasis | Amoebiasis | Soil-transmitted Helminthiasis | Intestinal Salmonellosis | Campylobacteriosis | Aeromonas Spp. Infections | Cryptosporidium Spp. Infections

Côte D'Ivoire, Indonesia, Mali, Nepal
Medical College of Wisconsin
Children's Hospital and Health System Foundation, Wisconsin

Completed

Plastic Bronchitis and Protein Losing Enteropathy in Children With Single Ventricle Physiology

Fontan Physiology Patients With PB or PLE | Fontan Physiology Patients Without PB or PLE

United States
University of California, Los Angeles

Unknown

Cysteine Supplementation in Critically Ill Neonates

Sepsis | Systemic Inflammatory Response Syndrome | Necrotizing Enterocolitis | Retinopathy of Prematurity | Bronchopulmonary Dysplasia

United States
Daiichi Sankyo
Merck Sharp & Dohme LLC

Recruiting

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Melanoma | Cervical Cancer | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Prostate Cancer | Bladder Cancer | Advanced Solid Tumor | Endometrial Cancer | Ovarian Carcinoma | Pancreatic Carcinoma

United States, Taiwan, Japan
Cancer Research UK
Heptares Therapeutics Limited

Recruiting

HTL0039732 in Participants With Advanced Solid Tumours

Sarcoma | Neoplasms | Kidney Neoplasms | Uterine Cervical Neoplasms | Stomach Neoplasms | Head and Neck Neoplasms | Lung Neoplasms | Urinary Bladder Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Mesothelioma, Malignant | Prostatic Neoplasms, Castration-Resistant | Pheochromocytomas

United Kingdom
Guardant Health, Inc.

Recruiting

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation (ORACLE)

Renal Cell Carcinoma | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Squamous Cell Carcinoma of the Head and Neck | Non-small Cell Lung Cancer | Fallopian Tube Carcinoma | Endometrial Carcinoma | Bladder Carcinoma | Esophageal Carcinoma | Invasive Breast Carcinoma | Cutaneous Melanoma | Epithelial Ovarian... and other conditions

United States
University Health Network, Toronto

Recruiting

Liquid Biopsy Evaluation and Repository Development at Princess Margaret (LIBERATE)

Melanoma | Lymphoma | Kidney Cancer | Leukemia | Cancer | Breast Cancer | Head and Neck Cancer | Ovarian Cancer | Lynch Syndrome | Lung Cancer | Colon Cancer | Meningioma | BRCA1 Mutation | BRCA2 Mutation | Myeloma | Mutation | Uterine Cancer | Cowden Syndrome

Canada
Seagen Inc.

Terminated

A Study of SGN-STNV in Advanced Solid Tumors

Uterine Cervical Neoplasms | Stomach Neoplasms | Colorectal Neoplasms | Esophageal Neoplasms | Ovarian Neoplasms | Endometrial Neoplasms | Pseudomyxoma Peritonei | Carcinoma, Non-Small Cell Lung | Gastroesophageal Junction Carcinoma | HER2 Negative Breast Neoplasms | Exocrine Pancreatic Adenocarcinoma | Appendiceal...

United States, United Kingdom, Canada, Spain, France, Italy
TCR2 Therapeutics

Active, not recruiting

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

Colorectal Neoplasms | Colorectal Cancer | Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Ovarian Neoplasms | Ovarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Mesothelioma, Malignant | Cholangiocarcinoma | Triple Negative Breast Cancer | Ovarian Adenocarcinoma | Mesotheliomas Pleural and other conditions

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb; National Cancer Institute (NCI); Iovance Biotherapeutics

Active, not recruiting

Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma

Malignant Solid Neoplasm | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Platinum-Resistant Ovarian Carcinoma | Metastatic Pancreatic Ductal Adenocarcinoma | Metastatic Ovarian Carcinoma and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

Sarcoma | Metastatic Melanoma | Thyroid Gland Carcinoma | Metastatic Malignant Neoplasm of Unknown Primary | Spinal Cord Compression | Stage IV Breast Cancer AJCC v6 and v7 | Malignant Digestive System Neoplasm | Metastatic Malignant Neoplasm in the Spine | Metastatic Kidney Carcinoma | Metastatic Head... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer

Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Postneoadjuvant... and other conditions

United States
Jerome Canady, M.D.

Active, not recruiting

Canady Helios Cold Plasma Scalpel Treatment at the Surgical Margin and Macroscopic Tumor Sites

Stage IV Lung Cancer | Stage IV Bladder Cancer | Stage IV Pancreatic Cancer | Recurrent Malignant Solid Neoplasm | Stage IV Breast Cancer | Stage IV Renal Cell Cancer | Stage IV Prostate Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer | Stage IV Gastric Cancer | Stage IV Non-small Cell Lung Cancer | Stage... and other conditions

United States
Stanford University

Terminated

Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors

Head and Neck Cancer | Colorectal Neoplasms | Lung Cancer | Colon Cancer | Colonic Neoplasms | Head and Neck Cancers | Anal, Colon, and Rectal Cancers | Colon/Rectal Cancer | Colon/Rectal Cancer Colon Cancer | Colon/Rectal Cancer Rectal Cancer | Colon/Rectal Cancer Anal Cancer | Head and Neck Cancers Lip | Head... and other conditions

United States
Cancer Research UK

Unknown

Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom

Lymphoma | Kidney Cancer | Pancreatic Cancer | Esophageal Cancer | Brain and Central Nervous System Tumors | Bladder Cancer | Intraocular Melanoma | Melanoma (Skin) | Transitional Cell Cancer of the Renal Pelvis and Ureter

United Kingdom
University of Aarhus

Not yet recruiting

Dysphagia and Quality of Life in Patients With Oral Squamous Cell Carcinoma Before and After Treatment

Quality of Life | Dysphagia | Oral Cavity Cancer

Denmark
UMC Utrecht
Karolinska University Hospital; Erasmus Medical Center; Great Ormond Street Hospital... and other collaborators

Not yet recruiting

Primary Posterior Tracheopexy Prevents Tracheal Collapse (PORTRAIT)

Oesophageal Atresia | Tracheomalacia | Oesophageal Atresia With Tracheo-Oesophageal Fistula
KK Women's and Children's Hospital
Singapore General Hospital; Duke-NUS Graduate Medical School; Genome Institute... and other collaborators

Recruiting

Saline Enema Administration in Meconium Obstruction of Prematurity and Impact on the Resolution, Feeds, Microbiome, and Gut-brain Axis.

Meconium Obstruction of Prematurity

Singapore
Cough Monitoring Medical Solutions
Universidade Nova de Lisboa

Recruiting

C-mo System 1.0's Validation - Cough Monitoring (C-mo_01)

Chronic Obstructive Pulmonary Disease | Cough | Asthma | Gastro Esophageal Reflux | Idiopathic Pulmonary Fibrosis

Portugal
University Hospital Southampton NHS Foundation...
University of Southampton; NeoKare Nutrition Ltd

Recruiting

Neokare Safety and Tolerability Assessment in Neonates With GI Problems

Anorectal Malformations | Gastroschisis | Hirschsprung Disease | Volvulus | Meconium Ileus | Intestinal Perforation | Preterm | NEC | Cows Milk Allergy | Atresia, Intestinal | Exomphalos

United Kingdom
University of Louisville
National Institutes of Health (NIH)

Recruiting

Recovery of Bladder and Sexual Function After Human Spinal Cord Injury

Blood Pressure | Urinary Bladder, Neurogenic | Autonomic Dysreflexia | Bowel Incontinence

United States
Regeneron Pharmaceuticals

Available

Compassionate Use of Pozelimab

Paroxysmal Nocturnal Hemoglobinuria (PNH) | CD55-deficient Protein-losing Enteropathy (PLE) | CD59 Deficiency
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood Gases (CO2)

Congenital Diaphragmatic Hernia | Esophageal Atresia With Tracheo-esophageal Fistula

United Kingdom
University Hospital Ostrava

Completed

Recurrent Respiratory Papillomatosis and Extraesophageal Reflux

Recurrent Respiratory Papillomatosis | Extra Oesophageal Reflux | Laryngeal Cyst

Czechia
University of North Carolina, Chapel Hill
VeinoPlus USA

Completed

Pilot Study for VeinoPlus to Improve Symptoms of Postthrombotic Syndrome (PTS) (VeinoPlus)

Deep Vein Thrombosis | Postphlebitic Syndrome | Post Thrombotic Syndrome | Venous Insufficiency | Venous Stasis Syndrome

United States
University Hospital, Lille
France Parkinson Association

Completed

Study of Dysarthria, Swallowing Disorders and Respiratory in Parkinson's Disease (ProdDiGYPark)

Parkinson's Disease

France
Hospital de Clinicas de Porto Alegre

Completed

Benefit From the Chin Down Maneuver in the Swallowing Performance and Self-perception of Parkinson's Disease Patients

Parkinson Disease | Speech Therapy | Orientation | Dysphagia, Oropharyngeal
Brigham and Women's Hospital
Shared Health, Chattanooga, TN

Unknown

Evaluation of a Regional Electronic Health Information Exchange's Clinical Health Record

Impact of Health Information Exchange on Patient Care | (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD, | Gastroenteritis, Seizures, and Bacterial Pneumonia)
Children's Cancer and Leukaemia Group

Unknown

Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01

Infertility | Ovarian Cancer | Sexual Dysfunction | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Gastrointestinal Complications | Urinary Complications | Pulmonary Complications | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Ireland, United Kingdom
Aroa Biosurgery Limited

Recruiting

Myriad™ Augmented Soft Tissue Reconstruction Registry (MASTRR)

Hidradenitis Suppurativa | Anal Fistula | Pressure Injury | Pilonidal Sinus | Necrotizing Soft Tissue Infection | Abdominal Wound Dehiscence | Lower Extremity Wound

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma

Malignant Solid Neoplasm | Melanoma | Colitis | Lung Non-Small Cell Carcinoma | Malignant Genitourinary System Neoplasm

United States
Lund University
Rigshospitalet, Denmark; University of Iceland; Skane University Hospital; Arba...

Enrolling by invitation

eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness (eChildHealth)

Preterm Birth | Congenital Heart Disease | Pediatric Cancer | Hirschsprung Disease | Nutrition Disorder, Child | Congenital Malformation

Denmark, Sweden
University Health Network, Toronto
University of Florida; National Institute on Deafness and Other Communication...

Completed

Physiological Flow of Liquids Used in Dysphagia Management (Neuro)

Parkinson Disease | Amyotrophic Lateral Sclerosis | Dysphagia

United States
Nanfang Hospital of Southern Medical University

Completed

Research on the Application and Mechanism of New Biological Probes in Biomedicine

Digestive System Diseases | Cardiovascular Diseases | Metabolic Diseases | Nervous System Diseases | Immune System Diseases | Endocrine System Diseases | Infectious Diseases | Tumors | Respiratory System Diseases | Urinary System Diseases | Blood Diseases

China
AbbVie

Completed

Post-marketing Observational Study to Evaluate the Incremental Impact of AbbVie's Patient Support Program on Patient Reported Outcomes and Health Resource Utilization in Inflammatory Arthritis, Psoriasis and Inflammatory Bowel Diseases in Hungary (VALUE) (VALUE)

Rheumatoid Arthritis | Psoriasis | Crohn's Disease | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylitis
University Health Network, Toronto

Terminated

Trial of Best Supportive Care and Either Cisplatin or Paclitaxel to Treat Patients With Primary Ovarian Cancer, Primary Peritoneal Cancer or Fallopian Tube Cancer and Inoperable Malignant Bowel Obstruction

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer | Bowel Obstruction

Canada
Danone Research

Terminated

Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation

Gastroenteritis | Sinusitis | Otitis | Bronchitis | Upper Respiratory Tract Infections | Sore Throat | Flu | Lower Respiratory Tract Infections | Rhinopharyngitis | Pneumopathy | Flu-like Syndromes

France
AstraZeneca

Completed

Nexium Capsules Helicobacter Pylori Specific Clinical Experience Investigation

Early Gastric Cancer | Gastric Ulcer | Duodenal Ulcer | Gastric Mucosa-associated Lymphoid Tissue (MALT) | Lymphoma Idiopathic Thrombocytopenic Purpura

Japan
West China Hospital

Not yet recruiting

A Lithium-containing Mouthwash Prevention and Treatment of Oral Mucositis and Dysgeusia in Patients Undergoing Radiotherapy

Head and Neck Squamous Cell Carcinoma | Malignant Head and Neck Tumors

China
University of British Columbia
Providence Health & Services; International Spinal Research Trust; International...

Recruiting

Below the Belt: Non-invasive Neuromodulation to Treat Bladder, Bowel, and Sexual Dysfunction Following Spinal Cord Injury

Sexual Dysfunction, Physiological | Spinal Cord Injuries | Neurogenic Bowel | Neurogenic Bladder | Spinal Cord Stimulation

Canada
Massachusetts General Hospital
Dana-Farber Cancer Institute

Recruiting

Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

Melanoma Stage IV | Melanoma Stage III | Drug Toxicity | Immune-related Adverse Event | Skin Cancer Stage III | Skin Cancer Stage IV | Drug-Induced Colitis

United States
TMRW Life Sciences
Dudley Associates Healthcare Marketing & Communications

Completed

The U.K. Embryologist Fatigue Study (FUSE-UK)

Gastrointestinal Diseases | Cardiovascular Diseases | Fatigue | Back Pain | Musculoskeletal Pain | Stress | Burnout, Professional | Chest Pain | Neck Pain | Sleep Disturbance | Syncope | Dizziness | Headache | Shortness of Breath

United States
McMaster University
Joseph Brant Hospital

Completed

The Effects of Whole-body Exercise to Improve Swallowing Function in Older Adults With Dementia

Parkinson Disease | Cough | Neuro-Degenerative Disease | Swallowing Disorder | Old Age; Dementia

Canada
TMRW Life Sciences
Dudley Associates Healthcare Marketing & Communications

Completed

The U.S. Embryologist Fatigue Study (FUSE)

Gastrointestinal Diseases | Cardiovascular Diseases | Fatigue | Back Pain | Musculoskeletal Pain | Stress | Burnout, Professional | Chest Pain | Neck Pain | Sleep Disturbance | Syncope | Dizziness | Headache | Shortness of Breath

United States
UCB BIOSCIENCES, Inc.
Syneos Health; Parexel

Terminated

UCB Cimzia Pregnancy Follow-up Study

Rheumatoid Arthritis (RA) | Crohn's Disease (CD) | Psoriatic Arthritis (PsA) | Axial Spondyloarthritis and Ankylosing Spondylitis

United States

Clinical Trials on Gastrointestinal Discomfort

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