Clinical Trials on Gastrointestinal Stromal Tumors (GISTs)

Total 1232 results

NRG Oncology
National Cancer Institute (NCI); Canadian Cancer Trials Group

Suspended

Tailoring Therapy in Post-surgical Patients With Low-risk Endometrial Cancer

Stage I Uterine Corpus Endometrial Stromal Sarcoma AJCC v8 | Stage II Uterine Corpus Endometrial Stromal Sarcoma AJCC v8 | Stage III Uterine Corpus Endometrial Stromal Sarcoma AJCC v8

United States
Infinity Pharmaceuticals, Inc.

Completed

Safety Study of IPI-504 in Patients With Gastrointestinal Stromal Tumors (GIST) or Soft Tissue Sarcomas (STS)

Gastrointestinal Stromal Tumors | Soft Tissue Sarcomas

United States, Canada
National Cancer Institute (NCI)

Completed

Belinostat in Treating Patients With Advanced Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer or Ovarian Low Malignant Potential Tumors

Recurrent Ovarian Carcinoma | Fallopian Tube Carcinoma | Primary Peritoneal Carcinoma | Stage IV Ovarian Cancer | Stage III Ovarian Cancer | Recurrent Borderline Ovarian Surface Epithelial-Stromal Tumor | Stage III Borderline Ovarian Surface Epithelial-Stromal Tumor | Stage IV Borderline Ovarian...

Canada
David Bushnell
National Cancer Institute (NCI); National Institutes of Health (NIH); Holden...

Active, not recruiting

Study to Evaluate the Safety of Combining Two Radionuclide Therapies to Treat Mid-gut Neuroendocrine Tumors

Neuroendocrine Tumor Gastrointestinal, Hormone-Secreting | Neuroendocrine Tumor, Malignant

United States
Prof. Dr. Cemil Tascıoglu Education and Research...

Completed

Mortality Predictions With Scorring Indices in Gastrointestinal Tumours

Gastrointestinal Tumours

Turkey
Stanford University
Caring for Carcinoid Foundation; GI Cancer Research Gift Fund

Withdrawn

Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers

Gastrointestinal Neoplasms | Pancreatic Cancer | Anal Cancer | Colon/Rectal Cancer | Hepatobiliary Cancers | Gastric (Stomach) Cancer | Gynecologic Cancers | Gastro-Esophageal(GE) Junction Cancer | Gynecologic Cancers Cervical Cancer | Gastrointenstinal Stromal Tumor (GIST) | Colon/Rectal Cancer Colon Cancer and other conditions

United States
Grupo Español de Tumores Huérfanos e Infrecuentes

Terminated

Ketoconazole as Inhibitor of the Enzyme CYP17 in Locally Advanced or Disseminated Granulosa Cell Tumour of Ovary (GreKo)

Granulosa Cell Tumour of the Ovary

Spain
China Medical University, China

Not yet recruiting

Anti-PD-1 Antibody Combined With Autologous DC and NK Cells in the Treatment of Digestive Carcinoma

PD-1 Antibody | Gastrointestinal Tumours | DC-Cell | NK-Cell
O'Dorisio, M S
National Cancer Institute (NCI)

Completed

Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors

Sarcoma | Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors | Neuroblastoma | Pheochromocytoma | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United States
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumor and Other Solid Tumor

Gastrointestinal Tumor

China
Changhai Hospital
Shanghai Ultra-T Immune Therapeutics Co. LTD

Not yet recruiting

A Clinical Study on the Safety and Efficacy of CAR-T Therapy for the TM4SF1-positive Tumors of Digestive System

Digestive Tumor
Stanford University

Terminated

Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal Cancers

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Pancreatic Adenocarcinoma | Neuroendocrine Tumors | Cholangiocarcinoma | Gastrointestinal Cancer | GIST, Malignant

United States
Gustave Roussy, Cancer Campus, Grand Paris

Terminated

Treatment of a Cancerous Disease of the Peritoneum With Complete Cytoreductive Surgery and Intraperitoneal Chemohyperthermia

Endocrine Tumors | Colon Tumors | Rectum Tumors | Appendix Tumors | Peritoneum Tumors

France
Lei Li

Recruiting

Prognosis of Low-grade Endometrial Stromal Sarcoma

Recurrence | Survival Outcomes | Adjuvant Therapy | Hormone Therapy | Low Grade Endometrial Stromal Sarcoma of Uterus (Diagnosis) | Fertility-sparing Surgery | Fertility Outcomes

China
University Health Network, Toronto
Princess Margaret Hospital, Canada

Recruiting

Non-Invasive Artificial Intelligence-Based Platform MonIToring Program (NIP IT!) (NIP IT!)

Melanoma | Breast Cancer | Gastrointestinal Neuroendocrine Tumor

Canada
Xencor, Inc.
ICON plc

Completed

A Study of XmAb®18087 in Subjects With NET and GIST

Neuroendocrine Tumor | Gastrointestinal Neoplasm

United States
Hellenic Cooperative Oncology Group
Novartis

Terminated

Study of Everolimus Treatment in Newly-diagnosed Patients With Advanced Gastrointestinal Neuroendocrine Tumors

Gastrointestinal Tumors | Pancreatic Neuroendocrine Tumors | Pancreatic Tumors | Gastrointestinal Neuroendocrine Tumors

Greece
Mid-Atlantic Oncology Program
Cancer Biotherapy Research Group

Completed

Fluorouracil Plus Interferon Alfa in Treating Patients With Advanced Metastatic Carcinoid Tumors

Lung Cancer | Gastrointestinal Carcinoid Tumor

United States
SpringWorks Therapeutics, Inc.

Active, not recruiting

Nirogacestat in Ovarian Granulosa Cell Tumors

Ovarian Cancer | Ovarian Granulosa Cell Tumor | Ovarian Granulosa-Stromal Tumor

United States, Canada, Poland
Centre Leon Berard

Recruiting

Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS) (BFR-ESS)

Low Grade Endometrial Stromal Sarcoma

France
Dana-Farber Cancer Institute
Bristol-Myers Squibb; Exelixis

Completed

Cabozantinib and Nivolumab for Carcinoid Tumors

Neuroendocrine Tumors | Carcinoid Tumor | Carcinoid Tumor of GI System

United States
Suzhou Immunofoco Biotechnology Co., Ltd

Recruiting

A Phase I Trial to Evaluate the Safety of IMC002 in Advanced Digestive System Tumors

Advanced Digestive System Tumor

China
Shanghai EpimAb Biotherapeutics Co., Ltd.
Labcorp Corporation of America Holdings, Inc

Recruiting

EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers

Neoplasms | Neoplasm Metastasis | Metastatic Gastrointestinal Carcinoid Tumor

United States, China
Western Sydney Local Health District

Recruiting

The Australia and New Zealand Multicentre Upper Gastrointestinal Endoscopic Tissue Resection Study (ANZ UGI)

Gastric Cancer | Esophageal Neoplasms | Neuroendocrine Tumors | Gastric Adenocarcinoma | Cancer of Stomach | Oesophageal Cancer | Gastric Neoplasm | GIST | GI Cancer

Australia
Chong Kun Dang Pharmaceutical

Completed

Study to Evaluate the Pharmacokinetic Characteristics of Luckyvec 400mg Tablet, in Healthy Subjects (Imatinib)

Gastrointestinal Stromal Tumors | Chronic Myeloid Leukemia

Korea, Republic of
Assistance Publique - Hôpitaux de Paris

Completed

Impact of the Inhibitors of Tyrosine Kinase on the Male Fertility (GLIFERTI)

Gastrointestinal Stromal Tumors | Chronic Myeloid Leukemia

France
University Health Network, Toronto

Active, not recruiting

A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients

Soft Tissue Sarcoma | Leiomyosarcoma | Endometrial Stromal Sarcoma | Malignant Peripheral Nerve Sheath Tumor (MPNST)

Canada
Pfizer

Completed

A Continuation Study Using Sunitinib Malate For Patients Leaving Treatment On A Previous Sunitinib Study.

Hepatocellular Carcinoma | Advanced Breast Cancer | Non-Small Cell Lung Cancer | Metastatic Breast Cancer | Metastatic Renal Cell Cancer | Thyroid Cancer | Pancreatic Neuroendocrine Tumor | Gastrointestinal Stromal Tumor | Advanced Gastric Cancer | Metastatic Castration Resistant Prostate Cancer | Advanced... and other conditions

United States, Spain, Korea, Republic of, France, Australia, United Kingdom, Canada, Brazil, Argentina, Taiwan, Belgium, Colombia, Germany, Hong Kong, Mexico, Philippines, Singapore
Aadi Bioscience, Inc.

Recruiting

Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors

Neuroendocrine Tumors | Pancreatic Neuroendocrine Tumor | Gastrointestinal Neuroendocrine Tumor | NET | Pulmonary Neuroendocrine Tumor

United States
University Health Network, Toronto

Completed

Luspatercept in Metastatic AGCT of the Ovary

Adult Granulosa Cell Tumor of the Ovary

Canada
National Cancer Institute (NCI)

Completed

Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma

Gastrointestinal Stromal Tumor | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Adult Rhabdomyosarcoma | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal... and other conditions
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

PS-341 in Treating Patients With Metastatic Neuroendocrine Tumors

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United States
Kyunghee University Medical Center

Completed

Usefulness of Near-focus With Narrow-band Imaging

Gastric Tumors

Korea, Republic of
Cambridge University Hospitals NHS Foundation Trust

Completed

Capecitabine and Streptozocin With or Without Cisplatin in Treating Patients With Unresectable or Metastatic Neuroendocrine Tumors

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United Kingdom
National Cancer Institute (NCI)

Terminated

Romidepsin in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Metastatic Gastrointestinal Carcinoid Tumor | Pancreatic Polypeptide Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Regional Gastrointestinal Carcinoid Tumor | Pulmonary Carcinoid Tumor

United States
Henan Cancer Hospital

Unknown

Etoposide/Cisplatin Compared With Irinotecan/Cisplatin for Advanced Gastrointestinal Neuroendocrine Tumor G3 Type

Gastrointestinal Neuroendocrine Tumor
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

AMG 706 and Octreotide in Treating Patients With Low-Grade Neuroendocrine Tumors

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

United States
Federation Francophone de Cancerologie Digestive

Completed

Combination Chemotherapy as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors of the Duodenum or Pancreas That Cannot Be Removed By Surgery

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome
University of California, San Francisco
Sanofi; Genentech, Inc.

Terminated

Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors

Lung Cancer | Neuroendocrine Tumor | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

United States
National Cancer Institute (NCI)

Completed

Temsirolimus in Treating Patients With Metastatic Neuroendocrine Carcinoma

Metastatic Gastrointestinal Carcinoid Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Pulmonary Carcinoid Tumor

Canada
Istituto Clinico Humanitas

Recruiting

EUS-Elastography and Contrast-Enhanced EUS Diagnostic Accuracy in the Differential Diagnosis of Subepithelial Gastrointestinal Tumors (SUNNYDAY)

Gastrointestinal Subepithelial Tumors

Italy
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Withdrawn

Vatalanib and Octreotide in Treating Patients With Progressive Neuroendocrine Tumors

Gastrointestinal Carcinoid Tumor | Islet Cell Carcinoma
Fondazione del Piemonte per l'Oncologia

Recruiting

SUNNYDAY: SUbepithelialgastroiNtestiNal Tumors Detection,accuracYDiAgnosis,ElastographY and Contrast-enhanced EUS (SunnyDay021)

Subepithelial Gastrointestinal Tumors

Italy
Peking University
Nanjing Legend Biotech Co.

Recruiting

A Study of LCAR-G08 in Subjects With Advanced Gastrointestinal Tumors Expressing Guanylyl Cyclase C (GCC)

Advanced Gastrointestinal Tumors

China
University of Southern California
National Cancer Institute (NCI)

Completed

Regorafenib in Treating Patients With Advanced or Metastatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Metastatic Gastrointestinal Carcinoid Tumor | Pancreatic Polypeptide Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Pulmonary Carcinoid Tumor

United States
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Recruiting

A Phase 1/2 Study of Donafenib in Combination With KN046 in Advanced Gastrointestinal Tumors

Advanced Gastrointestinal Tumors

China
Henan Cancer Hospital

Unknown

Treatment of Advanced Gastrointestinal Tumors With Albumin Taxol

Advanced Gastrointestinal Tumors

China
Taiho Oncology, Inc.

Completed

A Phase I Study of TAS-102 in Patients With Advanced Gastrointestinal Tumors.

Advanced Gastrointestinal Tumors

United States
Minneamrita Therapeutics LLC

Completed

Study of Minnelide™ in Patients With Advanced GI Tumors

Advanced Gastrointestinal Tumors

United States
Threshold Pharmaceuticals

Unknown

Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors (TH-CR-410)

Gastrointestinal Stromal Tumors | Advanced Renal Cell Carcinoma | Pancreatic Neuroendocrine Tumors

United States

Clinical Trials on Gastrointestinal Stromal Tumors (GISTs)

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