Clinical Trials on Gaucher Disease, Splenomegaly

Total 382269 results

Massachusetts General Hospital

Recruiting

Night Respite for Postpartum Mothers With SUD

Sleep Disorder | Opioid Use Disorder | Neonatal Opioid Withdrawal | Maternal Drugs Affecting Fetus | Postpartum Mood Disturbance

United States
Wayne State University

Recruiting

An Intervention to Enhance Well-Being in Trauma Exposed New Mothers

Post-traumatic Stress Disorder | Emotional Regulation | Maternal Behavior | Infant Behavior | Mood Disturbance | Maternal Distress | Maternal Care Patterns | Dissociation

United States
Imperial College London
Wellcome Trust; Imperial Clinical Trials Unit (ICTU)

Completed

PROState Pathway Embedded Comparative Trial (IP3-PROSPECT)

Prostate Cancer | Metastatic Prostate Cancer | Prostate Adenocarcinoma | Prostate Cancer Metastatic | Metastatic Prostate Carcinoma in the Soft Tissue | Non-metastatic Prostate Cancer

United Kingdom
TerSera Therapeutics LLC

Completed

Real-world Evidence Study EvaLuating PAtient-Reported Outcomes With XERMELO (RELAX)

Carcinoid Syndrome

United States
Cairo University

Completed

Comparison of the Efficacy of Calcium Hydroxide With Silver Nanoparticle and Conventional Calcium Hydroxide Intra Canal Medications on Post-Operative Pain in Symptomatic Root Canal Treatment Failure Cases: (CSNIMSRRT)

Pain | Postoperative | Discomfort | Root Canal Retreatment | Calcium Hydroxide | Intracanal Medicament | Ache | Retreatment | Nonsurgical Retreatment | Endodontic Failure | Symptomatic Endodontic Failure | Nanosilver | Intracanal Dressing | AgNPs | Ca (OH)2 | Flare up | Post-operative | Post Obturation

Egypt
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutation

Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Acute Myeloid Leukemia With FLT3/ITD Mutation | Acute Myeloid Leukemia With Gene Mutations | FLT3 Tyrosine Kinase Domain Point Mutation

United States
Masaryk Memorial Cancer Institute

Unknown

Acupuncture as the Therapeutic Modalities of Acute Toxicity in the Radiotherapy of Head and Neck Tumors

Malignant Tumor of Soft Tissue of Head, Face and Neck

Czechia
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Trial Comparing Simple Follow-up to Exploratory Laparotomy Plus "in Principle" (Hyperthermic Intraperitoneal Chemotherapy) HIPEC in Colorectal Patients (ProphyloCHIP)

Colorectal Cancer With a Resected Minimal Synchronous PC | Ovarian Metastases | Tumour Rupture in the Abdominal Cavity

France
Novartis Pharmaceuticals

Completed

Everolimus and Octreotide in Patients With Advanced Carcinoid Tumor (RADIANT-2)

Carcinoid Tumor | Malignant Carcinoid Syndrome

France, Spain, Netherlands, United States, Canada, Sweden, Italy, Australia, Germany, Greece, Belgium, Czech Republic, Slovakia, Finland, United Kingdom
Peking Union Medical College Hospital

Unknown

Outcomes of Pelvic Surgery With and Without Anti-incontinence Procedure in Occult Stress Urinary Incontinence Patients (PTOS)

Pelvic Organ Prolapse | Stress Urinary Incontinence | Other Specified Urinary Incontinence

China
Lexicon Pharmaceuticals

Completed

An Open-label Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]-Telotristat Etiprate in Males (LX1606-104)

Carcinoid Syndrome

United Kingdom
Dana-Farber Cancer Institute
Merck Sharp & Dohme LLC

Recruiting

Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Squamous Cell Carcinoma | Resectable Head and Neck Squamous Cell Carcinoma

United States
St. Luke's Health System, Boise, Idaho
Patient-Centered Outcomes Research Institute; University of Pennsylvania; Columbia... and other collaborators

Active, not recruiting

Suicide Prevention Among Recipients of Care (SPARC)

Adolescent | Depressive Disorder | Depression | Suicidal Ideation | Suicide, Attempted | Suicide | Mental Health | Loneliness | Social Support | Mental Disorder | Outpatients | Ambulatory Care | Continuity of Patient Care | Adult | Secondary Prevention | Emergency Service, Hospital | Mental Health Services | Patient Care Planning and other conditions

United States
VA Office of Research and Development

Completed

Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders (TBT-RCT)

Obsessive Compulsive Disorder | Generalized Anxiety Disorder | Major Depressive Disorder | Posttraumatic Stress Disorder | Panic Disorder | Social Phobia | Specific Phobia | Persistent Depressive Disorder

United States
Vanderbilt-Ingram Cancer Center
Boehringer Ingelheim; National Comprehensive Cancer Network

Withdrawn

Afatinib and Nivolumab as Treatment for Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Squamous Cell Carcinoma | Recurrent Squamous Cell Carcinoma of the Head or Neck | Metastatic Squamous Cell Carcinoma of the Head or Neck
Medical University of South Carolina
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Completed

Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD)

Addiction | Alcohol Abuse | Post Traumatic Stress Disorder (PTSD)

United States
Bern University of Applied Sciences
University of Bern

Unknown

Perinatal Mental Health Care in Switzerland (MADRE)

Depression | Anxiety Disorders | Post Traumatic Stress Disorder | Psychosis | Substance Abuse | Panic Disorder | Behavior Disorders | Mental Disorder | Health Care Utilization | Adaptation Reaction | Health Care Seeking Behavior | Health Care Acceptability | Perinatal

Switzerland
University of South Florida

Completed

Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism

Generalized Anxiety Disorder | Social Phobia | Separation Anxiety Disorder | Autism | Obsessive-compulsive Disorder | Asperger's Syndrome | Pervasive Developmental Disorder Not Otherwise Specified

United States
Centre for Addiction and Mental Health

Completed

Quetiapine in Co-Morbid Depressive and Anxiety Disorders

Anxiety Disorders | Generalized Anxiety Disorder | Major Depressive Disorder | Social Anxiety Disorder | Panic Disorder | Post-traumatic Stress Disorder | Dysthymic Disorder

Canada
University of California, San Diego

Recruiting

Brain Health Virtual Reality Study

Cognitive Change | Aging | Mild Cognitive Impairment | Cognitive Decline | Memory Disorders | Memory Impairment | Cognition Disorders in Old Age | Aging Problems | Memory Loss | Memory Disorders in Old Age | Memory Disorder, Spatial

United States
Sunnybrook Health Sciences Centre
University Health Network, Toronto; McMaster University; London Health Sciences...

Recruiting

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients (CODEX)

Mental Disorders | Nervous System Diseases | Neurologic Manifestations | Delirium | Confusion | Neurobehavioral Manifestations | Neurocognitive Disorders | Cognitive Dysfunction | Dexmedetomidine | Molecular Mechanisms of Pharmacological Action | Signs and Symptoms | Physiological Effects of Drugs | Analgesics,... and other conditions

Canada
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Recruiting

Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer

Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage IIA Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer AJCC v8

United States
Boehringer Ingelheim

Active, not recruiting

A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer

Head and Neck Squamous Cell Carcinoma (HNSCC)

Spain, United States, United Kingdom, France, Thailand, Malaysia, Mexico, Romania, Poland, Japan, Moldova, Republic of
Northwestern University
National Cancer Institute (NCI); Boehringer Ingelheim; Robert H. Lurie Cancer...

Active, not recruiting

Nintedanib and Azacitidine in Treating Participants With HOX Gene Overexpression Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A | Fibroblast Growth Factor Basic Form Measurement | FLT3 Internal Tandem Duplication

United States
Giselle Sholler
K C Pharmaceuticals Inc.; USWM, LLC

Available

An Intermediate Expanded Use Trial of DFMO

Embryonal Tumor With Abundant Neuropil and True Rosettes | Medulloblastoma | Neuroblastoma | Medulloepithelioma | Ependymoblastoma | Typical Teratoid Rhabdoid Tumor

United States
Hannover Medical School

Completed

Effect of Mother's Push at Cesarean Delivery Mother's PUSHING AT CS A RANDOMIZED CONTROLLED TRIAL

Caesarean Section | Postpartum Depression | Post Operative Pain | Mother-Child Relations

Germany
Nuvation Bio Inc.

Withdrawn

Study of NUV-422 in Combination With Enzalutamide in Patients With mCRPC

Prostate Cancer | Prostate Neoplasm | Cancer of the Prostate | Prostatic Cancer | Castrate Resistant Prostate Cancer | Cancer of Prostate | Castration Resistant Prostatic Cancer | Castration Resistant Prostatic Neoplasms

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Cancer Undergoing Surgery

Recurrent Prostate Cancer | Stage I Prostate Cancer | Stage III Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
University of Turin, Italy

Unknown

TLR Polymorphism, ASO and Beta-hemolytic Group A Streptococcus Infections in ADHD: an Observational Study (TLR;)

Attention Deficit-Hyperactivity Disorder

Italy
Balgrist University Hospital
University of Zurich

Terminated

3D Geplante Osteosynthesen Mit Patientenspezifischen Zielvorrichtungen

Fracture of Clavicle | Fracture of Femur | Fracture of Humerus | Fracture of Ulna Radius | Fracture of Hand | Fracture of Pelvis | Fracture of Tibia Fibula | Fracture of Skull

Switzerland
University of Washington
National Cancer Institute (NCI)

Completed

Niclosamide and Enzalutamide in Treating Patients With Castration-Resistant, Metastatic Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Recurrent Prostate Carcinoma | Castration Levels of Testosterone | Stage IV Prostate Adenocarcinoma

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); National Comprehensive Cancer Network

Terminated

Dabrafenib Alone and in Combination With Trametinib Before Surgery in Treating Patients With Locally or Regionally Advanced Melanoma That Can Be Removed By Surgery

Recurrent Melanoma | Stage IIIA Melanoma | Stage IIIB Melanoma | Stage IIIC Melanoma | Stage IIB Melanoma (Locally Advanced) | Stage IIC Melanoma (Locally Advanced) | Stage IV Melanoma (Limited, Resectable)

United States
Chinese University of Hong Kong
Hong Kong Young Women's Christian Association; Hong Kong Christian Service; Hong... and other collaborators

Recruiting

Video-conferencing FACT for Young Children With Special Needs

Autism Spectrum Disorder | Attention Deficit Hyperactivity Disorder | Communication Disorders | Specific Learning Disorder | Motor Disorders

Hong Kong
Indiana University

Recruiting

Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck

Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | Nonmelanoma Skin Cancer

United States
University of Washington
Centers for Disease Control and Prevention; Harborview Injury Prevention and...

Recruiting

Collaborative Opioid Taper After Trauma: Preventing Opioid Misuse and Opioid Use Disorder

Pain, Postoperative | Trauma | Opioid Use | Opioid-use Disorder | Opioid Use, Unspecified

United States
University of Texas Southwestern Medical Center
Stanford University

Recruiting

Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial) (PreVNT)

Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse) | Parent-Child Relations | Premature Infant | Development, Child

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Stage 4S Neuroblastoma | Ganglioneuroblastoma | Stage 2A Neuroblastoma | Stage 2B Neuroblastoma | Stage 3 Neuroblastoma | Stage 4 Neuroblastoma | Stage 1 Neuroblastoma | Stage 2 Neuroblastoma

United States, Canada, Australia, New Zealand
Accare

Completed

Psychosocial ADHD Interventions - Brief Parent Training (PAINT)

Behavioral Symptoms | Problem Behavior | ADHD | Child Behavior Problem | ADHD Predominantly Inattentive Type | ADHD - Combined Type | Behavior Problem | Disruptive Behavior | Behavioral Problem | ADHD, Predominantly Hyperactive-Impulsive Type

Netherlands
Sheba Medical Center

Completed

The Effect of Methylphenidate Treatment in Familial Attention Deficit/Hyperactivity Disorder (ADHD)

ADHD Predominantly Inattentive Type | Attention Deficit/Hyperactivity Disorder Combined Type | ADHD Predominantly Hyperactivity Type | ADHD-not Other Specified

Israel
University of California, San Francisco
Boston University; Boston Medical Center; Mbarara University of Science and Technology

Completed

Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT) (ADEPTT)

HIV/AIDS | Tuberculosis | Alcohol Abuse

Uganda
M.D. Anderson Cancer Center

Completed

Apalutamide and Gonadotropin-Releasing Hormone Analog With or Without Abiraterone Acetate in Treating Participants With Prostate Cancer

Prostate Adenocarcinoma | Stage IIIA Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer AJCC v8

United States
Douglas Mental Health University Institute
McGill University; Canadian Institutes of Health Research (CIHR); Jacobs Foundation and other collaborators

Completed

Maternal Adversity, Vulnerability and Neurodevelopment (MAVAN)

Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse) | Infant Behavior | Infant Development

Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor

Untreated Childhood Medulloblastoma | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

United States
Universiteit Leiden

Recruiting

Promoting Social-emotional Development and Self-esteem in Primary School Students

Healthy | Attention Deficit Hyperactivity Disorder | Prosocial Behavior | Anxiety Disorders and Symptoms | Peer Group | Emotional Problem | Self Esteem

Netherlands
VA Office of Research and Development
ACADIA Pharmaceuticals Inc.

Recruiting

Pimavanserin for Insomnia in Veterans With PTSD (PIP-II)

Insomnia | Post-traumatic Stress Disorder

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma

Recurrent Neuroblastoma | Stage 4S Neuroblastoma | Stage 2A Neuroblastoma | Stage 2B Neuroblastoma | Stage 3 Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada, Australia, New Zealand
Duke University
Boston Medical Center; Centers for Disease Control and Prevention; Children's...

Completed

FLUAD® vs. Fluzone® High-Dose Study

Quality of Life | Pain | Adverse Drug Event | Injection Site Reaction | Side Effect of Drug

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Sipuleucel-T With or Without Radiation Therapy in Treating Patients With Hormone-Resistant Metastatic Prostate Cancer

Recurrent Prostate Cancer | Bone Metastases | Hormone-resistant Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer | Soft Tissue Metastases

United States
University of California, San Francisco
Amgen

Withdrawn

Talimogene Laherparepvec in Treating Patients With Non-Muscle Invasive Bladder Transitional Cell Carcinoma

Stage 0a Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage 0is Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage I Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage 0 Bladder Urothelial Carcinoma AJCC v6 and v7

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Fluorothymidine F-18 PET in Diagnosing Patients With Intermediate or High Grade Soft Tissue Sarcoma

Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma | Stage IIA Adult Soft Tissue Sarcoma | Stage IIB Adult Soft Tissue Sarcoma | Stage IIC Adult Soft Tissue Sarcoma

Clinical Trials on Gaucher Disease, Splenomegaly

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