Clinical Trials on Gene Mutation-Related Cancer
Total 8293 results
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University of South FloridaBoston Children's HospitalCompletedPTEN Gene MutationUnited States
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Spark TherapeuticsCompletedChoroideremia | CHM (Choroideremia) Gene MutationsUnited States
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University Hospital, GrenobleCompletedHealthy Volunteers | Intellectual Deficiency | Asymptomatic Carrier of the Mutation of the Gene MYT1LFrance
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Blueprint Medicines CorporationActive, not recruitingNeoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | EGF-R Positive Non-Small Cell Lung... and other conditionsUnited States, Canada, Taiwan, Korea, Republic of, Singapore, Japan, United Kingdom, France, Netherlands, Spain
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Royal Marsden NHS Foundation TrustCompletedMRI | BRCA1 Mutation | BRCA2 Mutation | MammographyUnited Kingdom
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedBreast Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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SWOG Cancer Research NetworkNational Cancer Institute (NCI)Active, not recruitingStage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Lung Non-Small Cell Squamous Carcinoma | Recurrent Lung Non-Small Cell Carcinoma | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene Mutation | Recurrent Lung Adenocarcinoma | Loss of Heterozygosity | Recurrent... and other conditionsUnited States
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Stanford UniversityWithdrawnAdult Acute Myeloid Leukemia in Remission | Acute Myeloid Leukemia With Gene Mutations
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Nalo Therapeutics Inc.RecruitingEGFR Mutation-Related TumorsKorea, Republic of, United States, Taiwan
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National Cancer Institute (NCI)CompletedTherapy-Related Acute Myeloid Leukemia | Acute Myeloid Leukemia With FLT3/ITD Mutation | FLT3 Gene Mutation | Acute Promyelocytic Leukemia With PML-RARA | Acute Myeloid Leukemia With Inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11 | Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1United States
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The Affiliated Nanjing Drum Tower Hospital of Nanjing...RecruitingNSCLC | EGFR Gene MutationChina
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RWJ Barnabas Health at Jersey City Medical CenterUnknownLynch Syndrome | Endometrial Cancer | Somatic Mutation | Cancer Gene MutationUnited States
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ABM Therapeutics CorporationRecruitingAdvanced Solid Tumor | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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Centre Hospitalier Universitaire de BesanconCompletedBreast Cancer | BRCA1 Mutation | BRCA2 MutationFrance
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SpringWorks Therapeutics, Inc.AvailableDesmoid Tumor | NOTCH Gene Mutation Positive Tumors
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Georgetown UniversityCompletedPancreatic Cancer | Breast Neoplasm | BRCA1 Mutation | BRCA2 Mutation | Prostate CarcinomaUnited States
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Maximilian Stahl, MDSyndax PharmaceuticalsNot yet recruitingAcute Myeloid Leukemia | Leukemia | AML | AML, Adult | AML With Gene MutationsUnited States
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SensorionNot yet recruitingOtorhinolaryngologic Diseases | Ear Diseases | Hearing Disorders | Deafness | Hearing Loss, Sensorineural | Congenital Deafness | DFNB9 | OTOF Gene MutationFrance
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Agyany Pharma LTDRecruiting
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City of Hope Medical CenterNational Cancer Institute (NCI)Active, not recruitingBreast Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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Gynecologic Oncology GroupNational Cancer Institute (NCI)UnknownBreast Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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Betta Pharmaceuticals Co., Ltd.UnknownLung Cancer | ROS1 Gene RearrangementChina
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Hideho Okada, MD, PhDNational Cancer Institute (NCI); California Institute for Regenerative Medicine...RecruitingGlioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | MGMT-Unmethylated GlioblastomaUnited States
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European Organisation for Research and Treatment...AstraZenecaWithdrawnBRCA1 Mutation | BRCA2 Mutation | TNBC - Triple-Negative Breast Cancer
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Memorial Sloan Kettering Cancer CenterAstraZenecaRecruitingNSCLC | Lung Cancer | Non-small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Stage I | PD-L1 Gene Mutation | Non-small Cell Lung Cancer Stage IIIA | Non-small Cell Lung Cancer Stage IIUnited States
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Roswell Park Cancer InstituteCompletedStage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer | EGFR Gene MutationUnited States
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The Affiliated Hospital of Xuzhou Medical UniversityRecruitingType 2 Diabetes Mellitus | Genetic Mutations | Gene Polymorphisms | Susceptibility, GeneticChina
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Icahn School of Medicine at Mount SinaiMassachusetts General Hospital; National Institute of Neurological Disorders...RecruitingParkinson Disease | GBA Gene Mutation | LRRK2United States
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Northwestern UniversityNorthwestern Memorial Hospital; Saint Joseph Hospital, Chicago, IllinoisRecruitingBreast Cancer | BRCA MutationUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedHigh-Frequency Microsatellite Instability | Mismatch Repair Gene Mutation | Mutation-Negative Lynch Syndrome | Mutation-Positive Lynch SyndromeUnited States
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SwanBio Therapeutics, Inc.Active, not recruitingAMN | AMN Gene Mutation | X-ALDUnited States, Netherlands, Germany
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Georgetown UniversityGeorge Washington UniversityEnrolling by invitation
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Hunan Province Tumor HospitalNot yet recruitingLung Adenocarcinoma | ALK Gene Mutation | ImmunotherapyChina
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Jacobio Pharmaceuticals Co., Ltd.RecruitingSolid Tumors | ER+ Breast Cancer | ARID1A Gene Mutation | Triple Negative Breast Cancer, TNBC | Small Cell Lung Cancer, SCLCUnited States, China
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Seoul National University HospitalBayer; Korean Society of Breast Imaging & Korean Society For Breast ScreeningUnknownBreast Cancer | BRCA1 Mutation | BRCA2 Mutation | Recurrent Breast Cancer | Metachronous NeoplasmKorea, Republic of
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Tyra Biosciences, IncRecruitingSolid Tumor | Bladder Cancer | Advanced Solid Tumor | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Solid Tumor, Adult | FGFR3 Gene Mutation | Urinary Tract Cancer | Locally Advanced Urothelial Carcinoma | Advanced Urothelial Carcinoma | Non-muscle-invasive Bladder Cancer | FGFR3 Gene Alteration | Urinary... and other conditionsAustralia, United States, France, Spain
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Genzyme, a Sanofi CompanyCompletedEye Diseases | Macular Degeneration | Retinal Degeneration | Gene Therapy | Age-Related Maculopathies | Age-Related Maculopathy | Retinal Neovascularization | Maculopathies, Age-Related | Maculopathy, Age-Related | Therapy, GeneUnited States
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University Health Network, TorontoActive, not recruitingMutation | Hereditary Cancer Syndrome | High-Risk | Germline MutationCanada
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Chang Gung Memorial HospitalIntuitive SurgicalActive, not recruitingBreast Cancer | BRCA1 Mutation | BRCA2 Mutation | Nipple-sparing Mastectomy | Prophylactic MastectomyTaiwan
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Guangdong Provincial People's HospitalShanghai Junshi Bioscience Co., Ltd.RecruitingNon-Small Cell Lung Cancer | BRAF V600 Mutation | MET Amplification | MET Exon 14 Skipping Mutation | RET Driver Mutation | Erb-B2 Receptor Tyrosine Kinase Exon 20 MutationChina
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Royal Marsden NHS Foundation TrustPfizer; Breast Cancer NowActive, not recruitingGastric Cancer | Triple Negative Breast Cancer | Lobular Breast Carcinoma | CDH1 Gene MutationUnited Kingdom
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Stanford UniversityCompletedRecurrent Non-Small Cell Lung Carcinoma | KRAS Gene Mutation | Metastatic Malignant Neoplasm in the Brain | Stage IV Non-Small Cell Lung Cancer AJCC v7United States
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Second Affiliated Hospital of Guangzhou Medical...Sun Yat-sen University; The First Affiliated Hospital of Guangzhou Medical...RecruitingCancer | Lung Cancer | Gene Product Sequence Variation | Gene AbnormalityChina
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Masonic Cancer Center, University of MinnesotaRecruitingAcute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | AML | Acute Leukemia | Neurofibromatosis 1 | Hematologic Malignancy | Myelodysplasia | Minimal Residual Disease | Chromosome Abnormality | Monosomy 7 | Remission | Somatic Mutation | Cytogenetic Abnormality | TP53 | Fetal Hemoglobin | Intrachromosomal Amplification of Chromosome... and other conditionsUnited States
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Lei LiRecruitingEpithelial Ovarian Cancer | Homologous Recombination Deficiency | Homologous Recombination Repair Gene Mutation | Drug Resistance | Overall Survival | Progression-free Survival | Poly(ADP-ribose) Polymerase InhibitorChina
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CAI HongbingRecruitingOvarian Cancer | Epithelial Ovarian Cancer | Ovarian Cancer, Epithelial | Hyperthermic Intraperitoneal Chemotherapy(HIPEC) | Homologous Recombination Repair Gene MutationChina
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Fondazione I.R.C.C.S. Istituto Neurologico Carlo...University of Campania "Luigi Vanvitelli"; IRCCS National Neurological Institute...Active, not recruitingParkinson Disease | GBA Gene MutationItaly
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Stanford UniversityNot yet recruitingPTEN Gene Mutation | PTEN Hamartoma Tumor Syndrome | PTEN Hamartoma SyndromeUnited States
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David E GerberCancer Prevention Research Institute of Texas; Sagimet Biosciences Inc.Recruiting
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Shanghai Pulmonary Hospital, Shanghai, ChinaCompletedEGFR Gene Mutation | Lung Adenocarcinoma Stage IIIChina