Clinical Trials on Genetic Linkage

Total 14875 results

Daniel Doberer

Completed

Effects of Heme Arginate in Healthy Male Subjects (HEMAHS)

Healthy Subjects | Genetic Polymorphism | Heme Oxygenase

Austria
Universitaire Ziekenhuizen KU Leuven
KU Leuven; Universitair Ziekenhuis Brussel; Vrije Universiteit Brussel

Unknown

Genome-wide Single Cell Haplotyping as a Generic Method for Preimplantation Genetic Diagnosis

Preimplantation Genetic Diagnosis

Belgium
National Institute of Arthritis and Musculoskeletal...

Recruiting

Effects of Treatments on Atopic Dermatitis

Skin Diseases | Skin Diseases, Genetic | Dermatitis | Eczema | Dermatitis, Atopic

United States
Eli Lilly and Company

Completed

A Study of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroids in Japanese Participants With Moderate-to-Severe Atopic Dermatitis (ADhere-J)

Skin Diseases | Skin Diseases, Genetic | Dermatitis | Eczema | Dermatitis, Atopic

Japan
Dana-Farber Cancer Institute
Karyopharm Therapeutics Inc; William Lawrence and Blanche Hughes Foundation

Active, not recruiting

Phase I Trial of the Selective Inhibitor of Nuclear Export, KPT-330, in Relapsed Childhood ALL and AML

Relapsed Acute Lymphoblastic Leukemia (ALL) | Refractory Acute Lymphoblastic Leukemia (ALL) | Relapsed Acute Myelogenous Leukemia (AML) | Refractory Acute Myelogenous Leukemia (AML) | Relapsed Mixed Lineage Leukemia | Refractory Mixed Lineage Leukemia | Relapsed Biphenotypic Leukemia | Refractory... and other conditions

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Novel Genetic Disorders of the Immune System

CTLA4 | PI3KCD | STAT3GOF | MAGT1

United States
St. Jude Children's Research Hospital

Completed

Psychosocial Impact of Disclosing Cancer Predisposition Genetic Testing Results During Childhood

Pediatric Cancer | Predisposition, Genetic

United States
University Hospital, Angers

Recruiting

EXOme Rare Cancers in Children (EXOCARE) (EXOCARE)

Development Delay | Cancer Childhood | Predisposition, Genetic

France, Réunion
Shaare Zedek Medical Center

Unknown

Time-Lapse Incubation for Embryo Culture - Morphokinetics and Environmental Stability

Infertility | Genetic Diseases

Israel
Albany Medical College

Recruiting

The Accuracy of Amniotic Fluid Ferning in the Second Trimester in the Diagnosis of Preterm Prelabor Rupture of Membranes

Preterm Premature Rupture of Membrane | Amniotic Fluid Leakage

United States
Cantonal Hospital of St. Gallen

Completed

Does the Management of Anastomotic Leakage After Low Rectal Resection Affect Survival (ISRECLeak)

Rectal Cancer | Anastomotic Leak

Switzerland
Radboud University Medical Center
Dutch Upper-GI Cancer Audit group (DUCA); Oesophago-Gastric Anastomosis Audit...

Completed

TreatmENT of AnastomotiC Leakage After Esophagectomy (TENTACLE)

Esophageal Cancer | Esophageal Neoplasms

Netherlands
Mansoura University
University of Rome Tor Vergata

Completed

Anastomotic Leakage Following Laparoscopic Resection for Rectal Cancer

Anastomotic Leakage

Egypt, Italy
Odense University Hospital

Completed

Mediastinal Microdialysis in Patients With Oesophageal or Cardia Cancer Treated by Resection

Esophageal Cancer | Anastomotic Leakage

Denmark
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Efficacy of the Use of Genetic Markers in the Choice of the Pharmacological Treatment of Smoking (GENTSMOKING) (GENTSMOKING)

Smoking Cessation | Genetic Predisposition

Brazil
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Genetic Study of Obstructive Azoospermia

Genetic Disease

China
Erasmus Medical Center

Completed

Young Pectus Excavatum Patients and Genetic Defects

Genetic Disease | Children, Adult | Pectus Excavatum

Netherlands
Maastricht University Medical Center

Unknown

Follow-up of 5-year Old Children Born After PGD

Preimplantation Genetic Diagnosis

Netherlands
Rambam Health Care Campus
Israel Cancer Association

Withdrawn

Busulfan Pharmacokinetic Analysis and GST Polymorphism in Adults Undergoing Hematological Stem Cell Transplantation

Busulfan Pharmacokinetic Analysis | GST Genetic Polymorphism

Israel
Professor Ernest Hung-Yu Ng

Not yet recruiting

Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing

Infertility | Aneuploidy | Genetic Disease | Chromosomal Rearrangement

China
University Hospital, Strasbourg, France

Unknown

Non Invasive Prenatal Test of Rare Genetic Diseases: Application to Rare Intellectual Disabilities (DEFI)

Genetic Disorders in Pregnancy

France
Dana-Farber Cancer Institute

Not yet recruiting

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Population: The INFORM Study

Cancer Predisposition Syndrome | Predisposition, Genetic

United States
University of Edinburgh
Royal College of Surgeons of Edinburgh

Not yet recruiting

Does Genetic Susceptibility for Bleeding Affect Quantitative Faecal Immunochemical Test (qFIT) Results?

Colorectal Cancer | Colon Cancer
Institut National de la Santé Et de la Recherche...

Not yet recruiting

Genetic Susceptibility to Severe Infections (PREDISPOSITI)

Infectious Disease
University Hospital Tuebingen

Recruiting

Diagnostic Research in Patients With Rare Diseases - Solving the Unsolved Rare Diseases (DiRiP-RD)

Rare Diseases | Genetic Predisposition

Germany
University of Virginia

Not yet recruiting

Genetic Information Assistant in Telegenetics

Genetic Predisposition | Gene Mutation-Related Cancer
Institut Curie

Recruiting

COsegregation of VARiants in Panel of Genes (COVAR)

Genetic Predisposition | Gene Mutation-Related Cancer

France, Guadeloupe, Martinique, Réunion
Oxford Brookes University
St. Mary's University, Twickenham

Completed

Food Choice, Psychological Bias, and Genetic Predisposition

Food Preferences | Genetic Predisposition | Psychological

United Kingdom
Chang Gung Memorial Hospital

Recruiting

Investigation and Diagnosis of the Chromosome Variation in Donated/Abandoned Blastocyst

Recurrent Miscarriage | Chromosome Translocation | Genetic Disorders in Pregnancy

Taiwan
Maastricht University Medical Center
VieCuri Medical Centre; Zuyderland Medical Centre

Completed

Predictive Factors for Anastomotic Leakage After Colorectal Surgery (REVEAL)

Colorectal Neoplasms | Colorectal Cancer | Anastomotic Leak | Colorectal Tumors | Colorectal Carcinoma | Anastomotic Leakage

Netherlands
University of Guelph
McMaster University; Laval University

Not yet recruiting

Phe for Me? The Effects of L-Phe on PKU Carriers and Non-carriers (Phe for Me)

Autosomal Recessive Disorder (Genetic Carriers of PKU)

Canada
West Kazakhstan Medical University

Recruiting

Clinical and Genetic Markers of Bone Metabolism in Children Under One Year

Child Development | Genetic Change | Bone Remodeling Disorder

Kazakhstan
Hamilton Health Sciences Corporation
Southlake Regional Health Centre; Federal Economic Development Agency for Southern... and other collaborators

Completed

The DNA-Based Lifestyle Enhancement Trial (DNAble)

Health Behavior | Cardiovascular Risk Factor | Genetic Information

Canada
Hillel Yaffe Medical Center
Wingate Institute

Unknown

Genetic Polymorphism and Israeli Top-level Swimmers' Performance and Expertise

Genetic Polymorphism Connected to Top-level Swimmers

Israel
Eunice Kennedy Shriver National Institute of Child...
National Institutes of Health Clinical Center (CC); National Institute of Neurological... and other collaborators

Active, not recruiting

Skeletal Muscle Biomarkers in People With Fragile Sarcolemmal Muscular Dystrophy

Genetic Disorder

United States
The University of Hong Kong
The Hong Kong Polytechnic University

Active, not recruiting

Epidemiological Survey and Genetic Analysis of AD Patients in Hong Kong

Eczema | Atopic Dermatitis | Genetic Skin Disease

Hong Kong
University Hospital Tuebingen

Completed

Whole Genome Trio Sequencing as a Standard Routine Test in Patients With Rare Diseases - "GENOME FIRST APPROACH"

Rare Diseases | Genetic Predisposition

Germany
The Netherlands Cancer Institute

Recruiting

The Prospective Observational COMPRAYA Cohort Study (COMPRAYA)

Cancer | Fertility Issues | Genetic Disease | Lifestyle | Survivorship | Distress, Emotional | Second Cancer

Netherlands
Anhui Medical University

Not yet recruiting

Establishment of Reproductive Cohort and Prediction Model of Genetic Counseling for Mitochondrial Genetic Diseases

Mitochondrial Diseases
University Hospital, Geneva

Recruiting

Genetic Risks for Childhood Cancer Complications in Switzerland (GECCOS)

Childhood Cancer | Genetic Predisposition | Late Effect

Switzerland
Universidad Francisco de Vitoria

Completed

Genetics in the Effect of Caffeine on Fat Oxidation

Genetic Predisposition | Caffeine | Fat Burn

Spain
Zhejiang University

Completed

Epiction of the Genomic and Genetic Landscape Identifies CCL5 as a Protective Factor in Colorectal Neuroendocrine Carcinoma

Colorectal Neuroendocrine Carcinomas (CRNEC); Genomic Landscape; Genetic Landscape; Prognosis; CCL5; PAX5
University Hospital Tuebingen

Recruiting

Diagnostic Value of Exome/ Genome Sequencing, Conventional Methods in Rare Diseases and Familial Tumor Syndromes (EXGEFATU)

Rare Diseases | Genetic Predisposition

Germany
Duke University

Suspended

Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders

Lysosomal Storage Diseases | Genetic Disease | Inborn Errors of Metabolism | Glycogen Storage Disease | Storage Disease

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI); RTI International

Completed

Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease (ALIGN)

Hematologic Diseases | Sickle Cell Disease | Anemia, Sickle Cell | Genetic Disease

United States
Aesculap AG
B.Braun Surgical SA

Not yet recruiting

Endoluminal Vacuum Therapy to Prevent Anastomotic Leakage After Esophagectomy Due to Esophageal Cancer (ESPY)

Esophageal Cancer | Anastomotic Leak | Esophagus Cancer

Spain
University of Aarhus
Danish Cancer Society

Completed

Healing of Rectal Anastomosis Sealed With a Concentrate Derived From the Patient's Blood, After Rectal Cancer Surgery (OBANORES)

Rectal Cancer | Anastomotic Leak Rectum | Anastomotic Leakage

Denmark
University of Guelph
McMaster University

Recruiting

PKU Carriers Trial (Pilot Study): Impact on Cognition, Mental Health, Blood Pressure and Metabolism

Autosomal Recessive Disorder (Genetic Carriers of PKU)

Canada
Janssen Scientific Affairs, LLC

Approved for marketing

Expanded Access Program (EAP) for Participants With Advanced Cancers and Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations Who Have Exhausted All Treatment Options

Advanced Cancers and FGFR Genetic Alterations
National Taiwan University Hospital

Unknown

Establishment of Comprehensive Genetic Analysis From a Single Cell

Preimplantation Genetic Diagnosis (PGD)

Taiwan

Clinical Trials on Genetic Linkage

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