Clinical Trials on Genetic Mutations
Total 15590 results
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Synchron Medical, Inc.WithdrawnParalysis | Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Neurologic Disorder | Spinal Muscular Atrophy | Spinal Cord Injury | Stroke, Lacunar | Upper Limb Injury | Paralysis; Stroke | Stroke, BrainstemAustralia
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Emory UniversityChildren's Healthcare of AtlantaCompletedGlioma | Renal Cell Carcinoma | Astrocytoma | Osteosarcoma | Ependymoma | Medulloblastoma | Rhabdoid Tumor | Neuroblastoma | Retinoblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Germ Cell Tumor | Atypical Teratoid/Rhabdoid Tumor | Clear Cell Sarcoma | Ewing's SarcomaUnited States
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Roswell Park Cancer InstituteCompletedLymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Fanconi Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Aplastic AnemiaUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedRecurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Refractory Chronic Lymphocytic Leukemia | Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia and other conditionsUnited States
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University College CorkNot yet recruitingGestational Diabetes | Neonatal Encephalopathy | Diastolic Dysfunction | Trisomy 21 | Transient Tachypnea of the Newborn | Small for Gestational Age at DeliveryIreland
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University Hospital PadovaRecruitingHypertension | Essential Hypertension | Hyperaldosteronism | Aldosteronism | Conn Adenoma | Aldosterone Disorder | Aldosterone-producing Adenoma | Bilateral Adrenal HyperplasiaItaly
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National Cancer Institute (NCI)Active, not recruitingNeurofibroma | Neurofibromatosis Type 1 | Malignant Peripheral Nerve Sheath Tumor | Optic Glioma | Plexiform NeurofibromaUnited States
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Cyclo Therapeutics, Inc.Active, not recruitingNiemann-Pick Disease, Type C1United States, Taiwan, United Kingdom, Israel, Spain, Brazil, Italy, Australia, Turkey, Saudi Arabia, Argentina, Poland, Germany
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M.D. Anderson Cancer CenterActive, not recruitingAcute Lymphoblastic Leukemia | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia Chromosome Positive | B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Untreated Adult Acute Lymphoblastic Leukemia | Accelerated Phase Chronic Myelogenous Leukemia,... and other conditionsUnited States
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Bellicum PharmaceuticalsTerminatedLymphoma, Non-Hodgkin | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Primary Immunodeficiency | Anemia, Sickle Cell | Hemoglobinopathies | Fanconi Anemia | Anemia, Aplastic | Thalassemia | Cytopenia | Diamond Blackfan Anemia | Leukemia, Acute Myeloid (AML), ChildItaly
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Brigham and Women's HospitalOregon Health and Science University; Vanderbilt University; Geisinger ClinicCompletedMyocardial Infarction | Coronary Artery Disease | Smoking | Stroke | Hypertension | Chronic Obstructive Pulmonary Disease | Atrial Fibrillation | Asthma | Tuberculosis | Sleep Apnea | Sickle Cell Disease | Hyperlipidemia | Congestive Heart FailureUnited States
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Floor BackesTerminatedLynch Syndrome | Recurrent Endometrial Carcinoma | Recurrent Endometrial Clear Cell Adenocarcinoma | Recurrent Endometrial Cancer | Metastatic Endometrial Cancer | Mismatch Repair Deficiency | Recurrent Uterine Corpus CarcinosarcomaUnited States
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National Cancer Institute (NCI)CompletedJuvenile Myelomonocytic Leukemia | Recurrent Disease | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Childhood Solid Neoplasm | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia... and other conditionsUnited States, Canada
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Emory UniversityChildren's Healthcare of AtlantaCompletedRenal Cell Carcinoma | Osteosarcoma | Rhabdoid Tumor | Neuroblastoma | Retinoblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Ewings Sarcoma | Non-rhabdomyosarcoma Soft Tissue Sarcoma | Germ Cell Tumors | Clear Cell SarcomaUnited States
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M.D. Anderson Cancer CenterUnknownKidney Cancer | Colorectal Cancer | Bladder Cancer | Skin Cancer | Endometrial Cancer | Uterus CancerUnited States
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Brown, Theodore R., M.D., MPHCompletedStroke | Multiple Sclerosis | Parkinson's Disease | Brain Injury | Amyotrophic Lateral Sclerosis | Alzheimer's Disease | Spinal Cord Injury | Huntington's DiseaseUnited States
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Hadassah Medical OrganizationUnknownDiabetes Mellitus | Iron Metabolism Disorders | Optic Atrophy | Sensorineural Hearing Loss | Platelet Dysfunction | Gastroduodenal UlcerIsrael
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Millennium Pharmaceuticals, Inc.CompletedAcute Myeloid Leukemia | Multiple Myeloma | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Waldenstrom's Macroglobulinemia | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Non-Hodgkins Lymphoma | Myeloid Metaplasia | Philadelphia Chromosome-negative CML | Advanced PolycythemiaUnited States
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Udai KammulaRecruitingSarcoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Neuroendocrine Tumors | Mesothelioma | Merkel Cell Carcinoma | Microsatellite Instability | Squamous Cell Cancer | Mismatch Repair DeficiencyUnited States
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Volastra Therapeutics, Inc.RecruitingFallopian Tube Cancer | Primary Peritoneal Carcinoma | High Grade Serous Adenocarcinoma of Ovary | Chromosomal InstabilityUnited States
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Fundación Española de Hematología y HemoterapíaRecruitingGaucher Disease | Acid SphingoMyelinase DeficiencySpain
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M.D. Anderson Cancer CenterRecruitingBreast Cancer | Gynecologic Cancer | Pancreatic Cancer | Lynch Syndrome | Endometrial Cancer | Colon Cancer | Hereditary Breast and Ovarian Cancer Syndrome | Uterus Cancer | Ovary CancerUnited States
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Eunice Kennedy Shriver National Institute of Child...RecruitingTurner Syndrome | Galactosemia | Ovarian Disfunction | Post-menarcheal Adolescents | Variations in Sex Characteristics | Differences in Sex DevelopmentUnited States
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University of BaselRecruitingLynch Syndrome | Hereditary Breast and Ovarian CancerSwitzerland
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Eunice Kennedy Shriver National Institute of Child...CompletedPituitary Adenoma | Cushing's Syndrome | Carney Complex | Primary Pigmented Nodular Adrenocortical Disease | Peutz-Jeghers SyndromeUnited States
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Johns Hopkins UniversityNational Heart, Lung, and Blood Institute (NHLBI)Enrolling by invitationHypertrophic Cardiomyopathy (HCM) | Long QT Syndrome (LQTS) | Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) | Inherited Cardiac Arrythmias | Brugada Syndrome (BrS) | Early Repolarization Syndrome (ERS) | Arrhythmogenic Cardiomyopathy (AC, ARVD/C) | Dilated Cardiomyopathy (DCM) | Muscular... and other conditionsUnited States
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Natera, Inc.Children's Hospital of Philadelphia; Montefiore Medical Center; University of... and other collaboratorsCompletedPrader-Willi Syndrome | DiGeorge Syndrome | 22q11 Deletion Syndrome | Angelman Syndrome | Trisomy 21 | Trisomy 18 | Trisomy 13 | Monosomy X | Sex Chromosome Abnormalities | 1p36 Deletion Syndrome | Cri-du-Chat SyndromeUnited States, Australia, Ireland, Spain, Sweden, United Kingdom
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Sanford HealthNational Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaboratorsRecruitingMitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditionsUnited States, Australia
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Nemours Children's ClinicPotentials Foundation; Walking with Giants FoundationRecruitingMOPDII | RNU4atac-opathy (e.g. MOPDI/III, Lowry-Wood Syndrome, Roifman Syndrome) | Meier-Gorlin Syndrome | Saul-Wilson Syndrome | Ligase 4 Syndrome | Microcephalic Primordial DwarfismUnited States
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MD Stem CellsRecruitingGlaucoma | Age-Related Macular Degeneration | Macular Degeneration | Retinitis Pigmentosa | Leber Hereditary Optic Neuropathy | Optic Atrophy | Blindness | Optic Neuropathy | Vision, Low | Retinal Disease | Stargardt Disease | Maculopathy | Retinopathy | Optic Nerve Disease | Nonarteritic Ischemic Optic Neuropathy | Vision... and other conditionsUnited States, United Arab Emirates
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Washington University School of MedicineThe Foundation for Barnes-Jewish HospitalTerminatedLynch Syndrome | Hereditary Breast and Ovarian CancerUnited States
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AeRang KimTerminatedOsteosarcoma | Ewing Sarcoma | Neuroblastoma | Solid Tumors | Pediatric Cancer | Rhabdomyosarcoma | Wilms Tumor | Soft Tissue Sarcomas | Germ Cell Tumors | Hepatic TumorUnited States
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Geisinger ClinicNational Human Genome Research Institute (NHGRI)Active, not recruitingLynch Syndrome | Familial Hypercholesterolemia | Hereditary Breast and Ovarian Cancer SyndromeUnited States
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University Hospital OlomoucUniversity Hospital Ostrava; Tomas Bata Hospital, Czech Republic; General University... and other collaboratorsRecruitingCushing Syndrome | Pheochromocytoma | Adrenocortical Carcinoma | Adrenal Cortex Diseases | Adrenocortical Adenoma | Adrenal Tumor | Adrenalectomy; Status | Adrenal Mass | Adrenal Hyperplasia | Adrenal Disease | Adrenocortical Tumor | Conn Adenoma | Adrenal Gland MetastasisCzechia
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Oregon Health and Science UniversityRecruitingAmyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Multiple System Atrophy | Parkinson's Disease and Parkinsonism | Brain Tumor Adult | Locked-in Syndrome | Brainstem StrokeUnited States
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National Institute of Diabetes and Digestive and...RecruitingCystic Fibrosis | Turner Syndrome | Congenital Hepatic Fibrosis | Immunologic Deficiency Syndrome | Idiopathic Non-Cirrhotic Portal HypertensionUnited States
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University of California, Los AngelesUniversité de MontréalWithdrawnStroke | Epilepsy | Tuberous Sclerosis | Sturge-Weber Syndrome | Focal Cortical Dysplasia | Hemimegalencephaly | Polymicrogyria | Rasmussen Encephalitis | Gliosis | Tumor, BrainUnited States, Canada
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Bellicum PharmaceuticalsTerminatedLymphoma, Non-Hodgkin | Acute Lymphoblastic Leukemia | Primary Immunodeficiency | Anemia, Sickle Cell | Hemoglobinopathies | Fanconi Anemia | Anemia, Aplastic | Myelodysplastic Syndrome | Thalassemia | Cytopenia | Diamond Blackfan Anemia | Osteopetrosis | Leukemia, Acute Myeloid (AML), ChildUnited Kingdom, Italy
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Massachusetts General HospitalActive, not recruitingDepression | Obsessive Compulsive Disorder | Generalized Anxiety Disorder | Attention Deficit Hyperactivity Disorder | Trichotillomania | Panic Disorder | Social Phobia | Specific Phobia | Tourette Syndrome | Post-Traumatic Stress Disorder | Body Dysmorphic Disorder | Eating Disorder | General Medical ConditionUnited States
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Azienda Socio Sanitaria Territoriale degli Spedali...CompletedCerebellar Ataxia | Multiple System Atrophy | Spinocerebellar Ataxias | Spinocerebellar Degenerations | Spinocerebellar Ataxia 3 | Friedreich Ataxia | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Ataxia, Spinocerebellar | Ataxia, Cerebellar | Ataxia With Oculomotor ApraxiaItaly
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National Cancer Institute (NCI)CompletedRecurrent Thyroid Cancer | Recurrent Childhood Rhabdomyosarcoma | Papillary Thyroid Cancer | Recurrent Wilms Tumor and Other Childhood Kidney Tumors | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Liver Cancer | Childhood Hepatocellular CarcinomaUnited States, Canada, Australia
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Eunice Kennedy Shriver National Institute of Child...RecruitingNiemann-Pick Disease Type C1 | Juvenile Neuronal Ceroid Lipofuscinosis | Smith-Lemli-Opitz Syndrome | Creatine Transporter DeficiencyUnited States
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Patrick C. Johnson, MDAstraZenecaRecruitingRefractory B-Cell Non-Hodgkin Lymphoma | Diffuse Large B-cell Lymphoma (DLBCL) | Grade 3b Follicular Lymphoma | Refractory Aggressive B-cell Lymphomas | Aggressive B-cell NHL | De Novo or Transformed Indolent B-cell Lymphoma | DLBCL, Nos Genetic Subtypes | T Cell/Histiocyte-rich Large B-cell Lymphoma and other conditionsUnited States
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Duke UniversityNational Institute of Nursing Research (NINR); National Institutes of Health...CompletedChronic Kidney Diseases | Diabetes Mellitus, Type 1 | Systemic Lupus Erythematosus | Inflammatory Bowel Diseases | Cystic Fibrosis | Sickle Cell Disease | Stem Cell Transplant | Childhood Cancer | Organ TransplantUnited States
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University of PennsylvaniaThomas Jefferson University; Drexel UniversityCompletedNeurocognitive Disorders | Dementia | Alzheimer Disease | Lewy Body Disease | Frontotemporal Dementia | Vascular Dementia | Mixed Dementia | Pick Disease | Multi-Infarct DementiaUnited States
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CENTOGENE GmbH RostockTerminatedLymphangioleiomyomatosis | Subependymal Giant Cell Astrocytoma | Facial Angiofibroma | Cortical Dysplasia | Renal Angiomyolipoma | Hypomelanotic Macules | Shagreen Patches | Ungual Fibromas | Cardiac RhabdomyomaSri Lanka, Albania, Romania, Egypt, Pakistan, Georgia, India, Lithuania
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Burke Medical Research InstituteActive, not recruitingStroke | Multiple Sclerosis | Cerebral Palsy | Parkinson Disease | Spinal Cord Injuries | Neurologic Disorder | Hemiplegia | Hemiparesis | Friedreich Ataxia | Trauma, Brain | Transverse MyelitisUnited States
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LMU KlinikumCompletedHealthy | Myotonic Dystrophy Type 2 | Pompe Disease (Late-onset) | Spinal Muscular Atrophy Type 3 | Myotonic Dystrophy Type 1 (DM1) | Facioscapulohumeral Muscular Dystrophy 1 | Inclusion Body Myositis, SporadicGermany
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University College, LondonThe University of Hong KongActive, not recruitingDementia | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia Alzheimers | Dementia of Alzheimer Type | Dementia, Multi-Infarct | Dementia, Mild | Dementia Moderate | Dementia Frontal | Dementia FrontotemporalUnited Kingdom
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University of Southern CaliforniaNational Cancer Institute (NCI); Vasgene Therapeutics, Inc; Whittier FoundationTerminatedAcute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Philadelphia Chromosome Positive | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia and other conditionsUnited States