Clinical Trials on Genetic Signature in Development of Sarcomas

Total 455 results

dr. Laura C. G. de Graaff-Herder

Recruiting

Turner And Klinefelter Treatment Target Study (TAKTT)

Turner Syndrome | Klinefelter Syndrome

Netherlands
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Microcephaly, Fanconi Anemia and Praxial Disorders (MicroFancII)

Fanconi Anemia

France
University of Michigan
Patient-Centered Outcomes Research Institute; University of California, Los... and other collaborators

Completed

Decision Support for Parents Receiving Information About Child's Rare Disease (DSD DST)

Congenital Adrenal Hyperplasia | Hypospadias | Disorder of Sex Development | Intersex Conditions

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Adrenal Hyperplasia Among Young People With PCOS

Obesity | Hyperandrogenism | Polycystic Ovarian Syndrome | Oligomenorrhea | Adrenal Hyperplasia

United States
AstraZeneca

Completed

A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell Disease (HESTIA 1)

Investigation of Platelet Aggregation in Paediatric Patients With Sickle Cell Disease

United States, Canada, United Kingdom, South Africa, Lebanon, Kenya
National Cancer Institute (NCI)

Active, not recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Soft Tissue Sarcoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Osteosarcoma | Ewing Sarcoma | Recurrent Renal Cell Carcinoma | Refractory Malignant Solid Neoplasm | Rhabdomyosarcoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Malignant Solid Neoplasm | Recurrent Osteosarcoma | Recurrent... and other conditions

United States
Cairo University

Unknown

Hypo-mineralization of Primary and Permanent Teeth in a Group of Children With Stunted Growth.A Cross Sectional Study.

Hypomineralization of Enamel | Hypomineralization Molar Incisor | Short Stature

Egypt
Children's Hospital Medical Center, Cincinnati
Tourette Association of America

Recruiting

Theta Burst Stimulation to Improve Inhibitory Motor Physiology in Tourette Syndrome

Tourette Syndrome | Tourette Syndrome in Children | Tourette Syndrome in Adolescence | Tourette Syndrome, Modifier of

United States
University Hospital, Strasbourg, France

Recruiting

Interference by Activated Protein C Resistance in the Determination of Protein S Activity (PS)

Resistance to Activated Protein C in the Determination of Protein S Activity

France
University of California, San Francisco
United States Department of Defense

Recruiting

Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy (ReVIVE)

Multiple Sclerosis, Chronic Progressive | Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis (MS) | Multiple Sclerosis Relapse | Multiple Sclerosis, Primary Progressive | Multiple Sclerosis Brain Lesion | Multiple Sclerosis Benign

United States
University of Colorado, Denver

Completed

Health, Fitness, and Quality of Life in Adolescent Girls With Turner Syndrome

Turner Syndrome | Turner Syndrome Mosaicism, 45, X/46, XX or XY | Turner Syndrome Mosaicism 46,X,I(X)(Q10)/45,X | Turner Syndrome Karyotype 46,X With Abnormal Sex Chromosome , Except I(Xq)

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)

Marfan Syndrome | Turner Syndrome | Ehlers-Danlos Syndrome | Loeys-Dietz Syndrome | Shprintzen-Goldberg Syndrome | FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation | Bicuspid Aortic Valve Without Known Family History | Bicuspid Aortic Valve With Family History | Bicuspid Aortic Valve With Coarctation and other conditions

United States
Novo Nordisk A/S

Recruiting

Special Use-results Surveillance on Long Term Use of Sogroya® in Children With Short Stature Due to Growth Hormone Deficiency Where Epiphysial Discs Are Not Closed

Growth Hormone Deficiency in Children

Japan
University of California, Los Angeles
Université de Montréal

Withdrawn

Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery

Stroke | Epilepsy | Tuberous Sclerosis | Sturge-Weber Syndrome | Focal Cortical Dysplasia | Hemimegalencephaly | Polymicrogyria | Rasmussen Encephalitis | Gliosis | Tumor, Brain

United States, Canada
Maastricht University Medical Center

Enrolling by invitation

Reproductive Options in Inherited Skin Diseases (REPRO-ISD)

Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Xeroderma Pigmentosum | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
Rennes University Hospital

Completed

Haemochromatosis and Periodontitis (HEMOPARO)

to Evaluate the Prevalence of Periodontal Diseases in Patients With Hemochromatosis at the Time of Diagnosis and / or Their Usual Therapeutic
University of Colorado, Denver

Recruiting

The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy

Klinefelter Syndrome | Trisomy X | XYY Syndrome | XXXY and XXXXY Syndrome | Xxyy Syndrome | Xyyy Syndrome | Xxxx Syndrome | Xxxxx Syndrome | Xxxyy Syndrome | Xxyyy Syndrome | Xyyyy Syndrome | Male With Sex Chromosome Mosaicism

United States
Radboud University Medical Center
Princess Beatrix Muscle Foundation

Completed

Neuralgic Amyotrophy: Central Reorganization and Rehabilitation After Peripheral Dysfunction (NA-CONTROL)

Parsonage Turner Syndrome | Neuralgic Amyotrophy | Neuralgic Amyotrophy, Hereditary | Brachial Neuritis

Netherlands
National Eye Institute (NEI)

Completed

Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure

Menopause | Turner Syndrome | Ovarian Failure, Premature | Sex Chromosome Aberrations | Perimenopause

United States
Verinata Health, Inc.

Completed

Comparison of Aneuploidy Risk Evaluations (CARE)

Pregnancy | Down Syndrome | Edwards Syndrome | Patau Syndrome | Turners Syndrome

United States
Nanfang Hospital of Southern Medical University

Not yet recruiting

Site Preservation After Tooth Extraction

Osteogenesis Imperfecta | Tooth Socket | Total Absence of Permanent Teeth
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors

Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer | Stage IV Renal Cell Cancer | Clear Cell Sarcoma of the Kidney | Papillary Renal Cell Carcinoma | Rhabdoid Tumor of the Kidney | Stage I Renal Cell Cancer | Childhood Renal Cell Carcinoma | Stage II Renal Cell Cancer | Stage I Renal Wilms Tumor and other conditions

United States, Canada, Australia, New Zealand, Puerto Rico
Nemours Children's Clinic
Potentials Foundation; Walking with Giants Foundation

Recruiting

Primordial Dwarfism Registry

MOPDII | RNU4atac-opathy (e.g. MOPDI/III, Lowry-Wood Syndrome, Roifman Syndrome) | Meier-Gorlin Syndrome | Saul-Wilson Syndrome | Ligase 4 Syndrome | Microcephalic Primordial Dwarfism

United States
University of Aarhus

Recruiting

The Danish TURNER Cryopreservation Study (DANTE)

Fertility Disorders | Turner Syndrome | Premature Ovarian Failure

Denmark
Novo Nordisk A/S

Recruiting

A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow (REAL 8)

SGA, Turner Syndrome, Noonan Syndrome, ISS

Korea, Republic of, United States, Ireland, United Kingdom, Finland, France, Netherlands, Japan, Thailand, Belgium, China, Israel, Brazil, India, Portugal, Austria, Bulgaria, Canada, Croatia, Germany, Greece, Malaysia, Poland, Saudi Arabia and more
Novo Nordisk A/S

Recruiting

A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9 (REAL 9)

Turner Syndrome | Noonan Syndrome | SGA | ISS

Korea, Republic of, Malaysia, Netherlands, Spain, United States, Poland
Massachusetts General Hospital

Recruiting

Kisspeptin Administration in the Adult

PCOS | Kallmann Syndrome | Hypogonadotropic Hypogonadism | Polycystic Ovarian Syndrome | Hyperprolactinemia | GnRH Deficiency

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Study of the Disease Process of Lymphangioleiomyomatosis

Pneumothorax | Tuberous Sclerosis | Lung Disease | Lymphangioleiomyomatosis

United States
National Heart, Lung, and Blood Institute (NHLBI)
Suburban Hospital

Recruiting

Role of Genetic Factors in the Development of Lung Disease

Asthma | Pulmonary Fibrosis | Tuberous Sclerosis | Cystic Fibrosis | Pulmonary Sarcoidosis

United States
University College, London

Unknown

Pubertal Induction in Individuals With Hypogonadism

Hypopituitarism | Primary Ovarian Insufficiency | Turner's Syndrome | Hypogonadotrophic Hypogonadism | Primary Amenorrhoea | Hypothalamic Amenorrhoea

United Kingdom
University of Aarhus

Unknown

Prospective Characterization of the Heart, Aorta and Blood Pressure in Turner Syndrome. Association With Aortic Dissection. (TSCORII)

Hypertension | Ischemic Heart Disease | Aortic Aneurysm | Turner Syndrome | Congenital Heart Defect

Denmark
Oslo University Hospital
Norwegian National Advisory Unit on Rare Disorders, Oslo University Hospital

Recruiting

Quality of Life and Gut Health in Pediatric Patients With Cystic Fibrosis

Cystic Fibrosis in Children

Norway
The Cleveland Clinic

Completed

Natural History of Cherubism Observational Study

Cherubism

United States
UConn Health

Recruiting

Genetic and Functional Analysis of Cherubism (CBM)

Cherubism

United States
DePuy Orthopaedics

Recruiting

Actis Total Hip System 2 Year Follow-up (Actis14014)

Osteoarthritis | Rheumatoid Arthritis | Congenital Hip Dysplasia | Traumatic Arthritis | Avascular Necrosis of the Femoral Head | Acute Traumatic Fracture of the Femoral Head or Neck | Certain Cases of Ankylosis | Non-union of Femoral Neck Fractures | Certain High Sub-Capital & Femoral Neck Fractures...

United States
Murdoch Childrens Research Institute
National Health and Medical Research Council, Australia; Royal Children's Hospital and other collaborators

Recruiting

Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents (GenV)

Communicable Diseases | Quality of Life | Inflammation | Obesity | Congenital Abnormalities | Genetics | Healthy Aging | Child Development | Diet | Mental Health | Disability | Injuries | Cognition | Child Health | Environmental Exposure | Noncommunicable Diseases | Physical Fitness | Intergenerational Relations | Social Determinants... and other conditions

Australia
University of South Florida
National Institutes of Health (NIH); Rare Diseases Clinical Research Network

Completed

Osteogenesis Imperfecta (OI) Quality of Life Survey Pilot Project 2

Osteogenesis Imperfecta | Brittle Bone Disorders

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM) (EXIST-2)

Lymphangioleiomyomatosis (LAM) | Tuberous Sclerosis Complex (TSC)

United States, United Kingdom, Germany, Italy, Russian Federation, Netherlands, Japan, Canada, Poland, France, Spain
Sohag University

Completed

Sonographic Signs of Gouty Arthritis in a Cohort of Egyptian Patients: a Cross Sectional Multicenter Study

Sonographic Signs of Gouty Arthritis in Diagnosed and Suspected Patients

Egypt
Novartis Pharmaceuticals

Completed

Randomized, Controlled Study of CF Patients Between 3 Months and Less Than 7 Years (EARLY)

Treatment of Early Pulmonary Infections With P. Aeruginosa in Cystic Fibrosis Patients

Egypt, Greece, Hungary, Russian Federation, Canada, Germany, France, Italy, Switzerland, Romania
Centre Hospitalier Universitaire Vaudois
Swiss National Science Foundation

Recruiting

Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate

Kallmann Syndrome | Hypogonadotropic Hypogonadism | Hypothalamic Amenorrhea | Polycystic Ovarian Syndrome | Precocious Puberty | Cleft Lip and Palate | Cleft Palate | Cleft Lip

Switzerland
Universitätsklinikum Hamburg-Eppendorf
Pfizer; Bundesverband Kleinwüchsige Menschen und ihre Familien e.V.

Recruiting

Adaption and Testing of the Quality of Life in Short Stature Youth (QoLISSY) Questionnaire for Parents With Children From 0-4

Growth Hormone Deficiency | Achondroplasia | Small for Gestational Age

Germany
University of Aarhus
Aarhus University Hospital

Recruiting

Endocrine, Metabolic, Cardiovascular and Immunological Aspects of Sex Chromosome Abnormalities in Relation to Genotype (EMKISCA)

Cardiovascular Diseases | Turner Syndrome | Metabolic Disease | Klinefelter Syndrome | Immunologic Disease | Sex Chromosome Abnormality

Denmark
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Iovance Biotherapeutics, Inc.

Active, not recruiting

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

Malignant Solid Neoplasm | Soft Tissue Sarcoma | Recurrent Ovarian Carcinoma | Triple Negative Breast Cancer | Recurrent Osteosarcoma | Refractory Osteosarcoma | Bone Sarcoma | Giant Cell Tumor of Bone | Ovarian Carcinosarcoma | Platinum-Resistant Ovarian Carcinoma | Dedifferentiated Chondrosarcoma | Malignancy... and other conditions

United States
Assiut University

Recruiting

Management of Combined Fracture Neck of Femur and Femoral Deformity in Osteogenesis Imperfecta Patient (OI)

Osteogenesis Imperfecta

Egypt
University Hospital, Bordeaux

Recruiting

Functional Tests to Resolve Unsolved Rare Diseases. Rares. (RID)

Intellectual Disability | Cystic Fibrosis | Neurodegeneration With Brain Iron Accumulation (NBIA) | Congenital Heart Defect | Albinism | Rubinstein-Taybi Syndrome | Periventricular Nodular Heterotopia

France
Luminex Corporation

Completed

Clinical Evaluation of NeoPlex4 Assay and NeoPlex System

Adrenal Hyperplasia, Congenital | Cystic Fibrosis | Congenital Hypothyroidism

United States
Shanghai Jiao Tong University School of Medicine

Not yet recruiting

Comparisons of Different Forms of Glucocorticoid on the Recovery of Reproductive Function in Patients With 21α-hydroxylase Deficiency (CGP21)

Congenital Adrenal Hyperplasia

China
Diurnal Limited
National Institutes of Health (NIH)

Withdrawn

Open-label Comparison of Chronocort® Versus Standard Glucocorticoid Replacement Therapy (RESTORE)

Congenital Adrenal Hyperplasia

United States
Region Stockholm

Enrolling by invitation

Effects and Importance of Epinephrine/Adrenalin Deficiency in CAH

Congenital Adrenal Hyperplasia

Sweden

Clinical Trials on Genetic Signature in Development of Sarcomas

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cambodia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations