Clinical Trials on Genomic Imprinting in United Kingdom

Total 7721 results

Ultragenyx Pharmaceutical Inc

Active, not recruiting

A Study of the Safety and Tolerability of GTX-102 in Children With Angelman Syndrome

Angelman Syndrome

United States, United Kingdom, Canada, Australia, France, Germany, Spain, Israel
Ionis Pharmaceuticals, Inc.
Biogen

Active, not recruiting

HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome

Angelman Syndrome

United States, Israel, Italy, France, Australia, United Kingdom
Soleno Therapeutics, Inc.

Active, not recruiting

Open-Label Extension Study of DCCR in Patients With Prader-Willi Syndrome

Prader-Willi Syndrome

United States, United Kingdom
Soleno Therapeutics, Inc.

Completed

Open-Label Extension Study of DCCR in PWS Followed by Double-Blind, Placebo-Controlled, Randomized Withdrawal Period

Prader-Willi Syndrome

United States, United Kingdom
Hoffmann-La Roche

Recruiting

Study to Investigate the Pharmacokinetics and Safety and to Provide Proof of Mechanism of Alogabat in Children and Adolescents Aged 5-17 Years With Angelman Syndrome (AS) With Deletion Genotype. (Aldebaran)

Angelman Syndrome

Australia, United States, Spain, Italy, France, Germany
ACADIA Pharmaceuticals Inc.

Recruiting

Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome

Hyperphagia in Prader-Willi Syndrome

United States, Canada, United Kingdom
Hoffmann-La Roche

Active, not recruiting

A Study To Investigate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of RO7248824 In Participants With Angelman Syndrome

Angelman Syndrome

United States, Spain, Netherlands, Italy
The Leeds Teaching Hospitals NHS Trust
Genomic Medicine Services Alliance

Completed

Modified Delphi for Genomic Bereavement Care

Genetic Disease | Bereavement | Fetal Anomaly

United Kingdom
Oxford Brookes University
St. Mary's University, Twickenham

Completed

Food Choice, Psychological Bias, and Genetic Predisposition

Food Preferences | Genetic Predisposition | Psychological

United Kingdom
University of Leicester

Active, not recruiting

A Study to Evaluate the Feasibility of Screening Relatives of Patients Affected by Non-Syndromic Thoracic Aortic Diseases (ReST)

Genetic Disease | Screening | Aortic Aneurysm and Dissection

United Kingdom
Harmony Biosciences, LLC

Recruiting

A Study of Pitolisant in Patients With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Neuren Pharmaceuticals Limited

Recruiting

An Open-Label Study of Oral NNZ-2591 in Prader-Willi Syndrome (PWS-001) (PWS-001)

Prader-Willi Syndrome

United States
Nottingham University Hospitals NHS Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; Manchester... and other collaborators

Recruiting

A Comprehensive Approach To Relief Of Digestive Symptoms In Cystic Fibrosis: CARDS-CF (CARDS-CF)

Respiratory Tract Diseases | Lung Diseases | Cystic Fibrosis | Genetic Disease | Digestive System Disease | Pancreatic Disease

United Kingdom
University of Oxford
University College, London; Moorfields Eye Hospital NHS Foundation Trust

Completed

REP1 Gene Replacement Therapy for Choroideremia (REGENERATE)

Choroideremia

United Kingdom
Royal Cornwall Hospitals Trust

Completed

A Retrospective Validations Microsatellite Instability (MSI) Testing v Mismatch Repair (MMR) in Gastric Adenocarcinoma

Gastric Cancer

United Kingdom
BenevolentAI Bio

Completed

A First-in-Human PoC Study With BEN2293 in Patients With Mild to Moderate Atopic Dermatitis

Atopic Dermatitis

United Kingdom
King's College London
University of Nottingham; Imperial College London; University of Sheffield; Guy... and other collaborators

Unknown

Softened Water for Eczema Prevention Pilot Trial (SOFTER)

Atopic Eczema

United Kingdom
Aerovance, Inc.

Completed

A Phase 2a Study to Investigate the Effects of Repeated Administration of AeroDerm in Subjects With Atopic Eczema

Atopic Eczema

United Kingdom
Atopix Therapeutics, Ltd.

Completed

Effect of OC000459 on Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United Kingdom
University of Dundee
NHS Tayside

Completed

Narrowband Ultraviolet B Versus Narrowband Ultraviolet B Plus Ultraviolet A1 for Atopic Eczema

Atopic Eczema

United Kingdom
University College, London
Dermatrust

Withdrawn

Investigating Immune Mechanisms in Atopic Eczema

Atopic Dermatitis

United Kingdom
GlaxoSmithKline

Completed

Investigation of Topical SB705498 on Healthy Volunteers

Dermatitis, Atopic

United Kingdom
Origin Sciences

Completed

Exploratory Study of Rectal Mucus for Diagnosing Disease (ORI-EGI-02)

Bowel Cancer | Bowel Disease | Epigenetic Disorder | Genomic

United Kingdom
Momentum Data
Pfizer; Royal College of General Practitioners Research and Surveillance Centre

Unknown

Trends in the Epidemiology and Treatment of Atopic Dermatitis in the United Kingdom (UK)

Eczema | Atopic Dermatitis | Atopic Dermatitis Eczema

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; National Institute for Health Research, United Kingdom

Completed

Role of Anti-IgE in Severe Childhood Eczema (ADAPT)

Child | Atopic Dermatitis | Atopic Eczema

United Kingdom
Imperial College London
JP Moulton Charitable Foundation

Recruiting

TLA in Children With Moderate to Severe Atopic Eczema (TLA4AE)

Atopic Dermatitis Eczema

United Kingdom
ACO Hud Nordic AB
The University of Sheffield Medical School

Completed

A NOVel Moisturiser for Atopic Dermatitis: Effect on the Skin Barrier

Dermatitis, Atopic

United Kingdom
University of Ulster

Completed

Blood Pressure Lowering Effect of B-vitamins in Adults With a Genetic Pre-disposition to Elevated Blood Pressure. (RAFA)

Blood Pressure

United Kingdom
LEO Pharma

Completed

LEO 29102 Single and Multiple Dose Study by Dermal Application

Atopic Dermatitis

United Kingdom
Imperial College London
Sarepta Therapeutics, Inc.; Department of Health, United Kingdom

Completed

Safety and Efficacy Study of Antisense Oligonucleotides in Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

United Kingdom
AnaMar AB
Covance

Completed

A Study to Assess the Safety, Tolerability, PK and PD of AM1030-CREAM in Patients With Atopic Dermatitis

Atopic Dermatitis

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Cardiff University; University of Surrey

Completed

Proof of Concept Study for a Dressing Glove

Epidermolysis Bullosa Dystrophica

United Kingdom
University of Aberdeen

Recruiting

Is There a Genetic Predisposition for Acute Stress-induced (Takotsubo) Cardiomyopathy (GENETIC)

Takotsubo Cardiomyopathy

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Unknown

Gene Therapy for Netherton Syndrome

Netherton Syndrome

United Kingdom
Novo Nordisk A/S

Completed

Use of Somatropin in Turner Syndrome

Turner Syndrome | Genetic Disorder

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; University of Oxford; Queen Mary University... and other collaborators

Recruiting

The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and Treatment (PROFILE)

Prostate Cancer | Genetic Counselling | Genetic Markers | Prostate Biopsy

United Kingdom
St Mary's University College
Fulham Football Club

Completed

Candidate Gene Association Study With Injury in Elite Male Youth Football Players

Injuries | Genetic Change

United Kingdom
King's College London
University College, London

Completed

Safety Study of Gene-modified Autologous Fibroblasts in Recessive Dystrophic Epidermolysis Bullosa

Recessive Dystrophic Epidermolysis Bullosa

United Kingdom
University College, London

Recruiting

Liver Biopsy In Haemophilia Gene Therapy

Hemophilia A, Severe | Hemophilia B, Severe

United Kingdom
King's College London

Unknown

Mesenchymal Stromal Cells in Adults With Recessive Dystrophic Epidermolysis Bullosa (ADSTEM)

Recessive Dystrophic Epidermolysis Bullosa

United Kingdom
St Mary's University College

Completed

The Genetic Effects of rs7903146 and Dietary Intake on Type 2 Diabetes Mellitus Risk in a Healthy Population

Health Behavior | Diet Habit | Genetic Predisposition | Blood Glucose, High

United Kingdom
LEO Pharma

Completed

Safety and Tolerability of LEO 138559 in Healthy Subjects and Subjects With Atopic Dermatitis

Atopic Dermatitis

United Kingdom
Ziarco Pharma Ltd

Completed

A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and in Subjects With Atopic Dermatitis

Atopic Dermatitis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Active, not recruiting

A Longitudinal Investigation of Skin Barrier Development From Birth and the Validation of Early Predictors of Atopic Eczema Risk: the Skin Testing for Atopic Eczema Risk (STAR) Study (STAR)

Atopic Eczema

United Kingdom
Astellas Pharma Europe B.V.

Completed

Locobase® REPAIR Used as an Adjunctive to Standard Therapy in Children With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

United Kingdom
Genethon

Active, not recruiting

Gene Therapy for X-linked Chronic Granulomatous Disease (X-CGD) (CGD)

X-Linked Chronic Granulomatous Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Newcastle University; University of Cambridge

Completed

XPAND Trial: Enhancing XP Photoprotection Activities - New Directions (XPAND)

Xeroderma Pigmentosum

United Kingdom
University College, London

Recruiting

Halting Ornithine Transcarbamylase Deficiency With Recombinant AAV in ChildrEn (HORACE)

Ornithine Transcarbamylase Deficiency

United Kingdom
St Mary's University College
Fulham Football Club

Completed

Total Genotype Score, Growth, Maturation and Loading Exposure as Risk Factors for Injury in Elite Male Youth Football

Tendon Injuries | Apophysitis | Genetic Predisposition | Ligament Injury | Muscle Strain | Fractures in Children

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cancer Research UK; Ronald and Rita McAulay...

Active, not recruiting

The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte Cancer

Prostate Cancer in BRCA1 and BRCA2 Carriers

United Kingdom

Clinical Trials on Genomic Imprinting in United Kingdom

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