Clinical Trials on Glaucoma, Angle-Closure in United Kingdom

Total 976 results

Ocular Therapeutix, Inc.

Completed

Phase 2b Study Evaluating Safety and Efficacy of OTX-TP Compared to Timolol Drops in the Treatment of Subjects With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

United States
New World Medical, Inc.

Completed

A Comparison of Two Ab Interno Procedures in the Treatment of Glaucoma in Patients Undergoing Cataract Extraction

Open Angle Glaucoma

United States
Sight Sciences, Inc.

Unknown

Use of the OMNI® Surgical System in Combination With Cataract Extraction in Open Angle Glaucoma

Open Angle Glaucoma

United States
Glaukos Corporation

Completed

Study of Exchange of Travoprost Intraocular Implant

Open Angle Glaucoma

United States, Philippines
Glaukos Corporation

Completed

Post-approval Study of The Glaukos® iStent® Trabecular Micro-bypass Stent: Extended Follow-up of the Premarket Cohort

Primary Open Angle Glaucoma

United States
Bausch & Lomb Incorporated

Completed

BOL-303259-X With Timolol 0.5% in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Constellation)

Ocular Hypertension | Open Angle Glaucoma

United States
Santa Clara Valley Health & Hospital System
OptiMedica Corporation

Completed

Evaluation of Pascal Laser Trabeculoplaty (PLT)

Ocular Hypertension | Open Angle Glaucoma

United States
Nova Eye, Inc.

Terminated

Multicenter Ab-interno Glaucoma Study Investigating Canaloplasty (MAGIC)

Primary Open Angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Study Comparing the Safety and Efficacy of AR-13324 to Latanoprost in Patients With Elevated Intraocular Pressure

Ocular Hypertension | Open Angle Glaucoma

United States
Vistakon Pharmaceuticals

Completed

Patient Satisfaction With Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open Angle

United States
Temple University

Completed

180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma

Ocular Hypertension | Glaucoma | Open Angle Glaucoma | Pigment Dispersion Syndrome | Glaucoma, Open Angle, Pseudo-exfoliative

United States
Qlaris Bio, Inc.

Completed

Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Northwestern Ophthalmic Institute S.C.
Research to Prevent Blindness

Completed

Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Aerie Pharmaceuticals

Completed

Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United Kingdom, Spain, Austria, Belgium, Czechia, France, Germany, Hungary, Italy, Latvia, Poland
Whitecap Biosciences, LLC

Completed

Safety and IOP-Lowering Effects of WB007

Ocular Hypertension | Glaucoma, Primary Open Angle

United States
Nephron Pharmaceuticals Corporation

Completed

Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Alcon Research
University of California, San Diego

Completed

Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
University of California, San Francisco
University of Colorado, Denver; University of Maryland; Zhongshan Ophthalmic... and other collaborators

Completed

Ahmed Glaucoma Valve Surgery With Mitomycin-C (AMCT)

Primary Open Angle Glaucoma | Glaucoma | Neovascular Glaucoma | Secondary Glaucoma

United States, China, India, Mexico
ViSci Ltd.

Completed

A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival Latanoprost Insert in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma or Ocular Hypertension

United States
Santen Inc.

Completed

Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Allergan

Completed

A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension

Glaucoma | Open-Angle Ocular Hypertension

Spain, United States, Singapore, Australia, Denmark, France, Poland, Russian Federation, Thailand
Alcon Research

Recruiting

Hydrus® Microstent New Enrollment Post-Approval Study (CONFIRM)

Primary Open Angle Glaucoma

United States
Glaukos Corporation

Recruiting

Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
JeniVision, Inc.

Suspended

Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
Nicox Ophthalmics, Inc.

Completed

Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Mont Blanc)

Ocular Hypertension | Open Angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

24-hour Efficacy of AR-12286

Ocular Hypertension | Open Angle Glaucoma

United States
Mati Therapeutics Inc.

Completed

A Safety Study of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open Angle Glaucoma

Ocular Hypertension | Glaucoma

United States
Ocuphire Pharma, Inc.

Completed

Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucoma

Ocular Hypertension | Open Angle Glaucoma

United States
Alcon Research

Completed

A 6-week Safety & Efficacy Study of Combination Intraocular Pressure-lowering Therapy in Patients With Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-angle

United States
Alcon Research

Completed

Travatan Versus Timoptic in Treating Open-angle Glaucoma or Ocular Hypertension

Glaucoma

United States
Santen Inc.

Completed

DE-117 Spectrum 5 Study

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Sun Pharma Advanced Research Company Limited

Completed

Evaluation of Safety of SPARC0913 in Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
Sun Pharma Advanced Research Company Limited

Completed

Efficacy and Safety of SPARC0912 and Reference0912 in Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
Peregrine Ophthalmic

Completed

POLAT-001 Compared to Latanoprost Ophthalmic Solution in Patients With Ocular Hypertension and Open-angle Glaucoma

Glaucoma

United States
Altheos, Inc.

Completed

ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular Hypertension (OHT) Subjects

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Inotek Pharmaceuticals Corporation

Completed

A Dose-Escalation Study Designed to Evaluate the Tolerability, Safety, Pharmacokinetics (PK), and Efficacy of Chronic Topical Ocular Application of INO-8875 in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma

Ocular Hypertension | Glaucoma

United States
MediPrint Ophthalmics, Inc.

Completed

Study of LL-BMT1 in Patients With Elevated Intraocular Pressure

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Mati Therapeutics Inc.

Completed

Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Glaucoma

United States
Ocular Therapeutix, Inc.

Completed

Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT

Ocular Hypertension | Open Angle Glaucoma

United States
59th Medical Wing
Nanodropper, Inc.

Recruiting

Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).

Glaucoma

United States, Singapore
Eye Therapies, LLC

Completed

Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension

Glaucoma and Ocular Hypertension

United States
Sylentis, S.A.

Completed

SYL040012, Treatment for Open Angle Glaucoma (SYLTAG)

Ocular Hypertension | Open Angle Glaucoma

Spain, Germany, United States, Estonia
Chicago Center for Vision Research

Completed

Study of Medical Treatment of Low-Pressure (Normal Tension) Glaucoma

Glaucoma, Open Angle

United States
InSight Vision Center Medical Group, Inc

Recruiting

Hydrus Microstent as a Quality of Life Consideration

Open Angle Glaucoma

United States
University of Colorado, Denver

Completed

The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion Pressure

Hypertension, Ocular | Glaucoma, Open-angle

United States
Skye Bioscience, Inc.

Completed

Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressure

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Glaukos Corporation

Active, not recruiting

Multicenter Post-Approval Study Of The Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery

Primary Open Angle Glaucoma

United States
Hoffmann-La Roche

Completed

A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-angle

United States

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