Clinical Trials on Glaucoma, Congenital

Total 10791 results

Alcon Research

Completed

Efficacy and Safety of Travoprost 0.004% Versus Tafluprost 0.0015% in Patients With Primary Open-angle Glaucoma or Ocular Hypertension

Glaucoma
Medical University of Vienna

Completed

Polymorphisms in the Human Matrix Metalloproteinase Genes MMP1, MMP3, and MMP9: Genetic Risk Factors of Primary Open Angle Glaucoma?

Glaucoma

Austria
Medical University of Vienna

Completed

Correlation of Optic Disk Morphology and Ocular Perfusion Parameters in Patients With Primary Open Angle Glaucoma

Primary Open Angle Glaucoma

Austria
National Taiwan University Hospital

Not yet recruiting

Regulation of Intraocular Pressure in Glaucoma Patients by Acupressure

Primary Open Angle Glaucoma | Acupressure
New World Medical, Inc.

Completed

A FIH Trial of the STREAMLINE™ SURGICAL SYSTEM

Intraocular Pressure | Open Angle Glaucoma

Mexico
University of the Incarnate Word
Guardion Health Sciences, Inc.

Withdrawn

Augmented Macular Pigment-containing Nutraceutical and Central Visual Function

Glaucoma | Glaucoma, Open-Angle | Glaucoma Eye

United States
OPKO Health, Inc.

Completed

A Prospective, Multicenter, Open-label, Safety and Preliminary Efficacy Study of the Surgical Implantation of OPKO's Glaucoma Drainage Device (AquashuntTM) in Patients With Refractory Chronic Forms of Open Angle Glaucoma (OAG)

Glaucoma

Dominican Republic
Second Affiliated Hospital, School of Medicine,...

Unknown

Efficacy Evaluation and Influencing Factors of Argon Laser Peripheral Iridoplasty in Acute Angle Closure Glaucoma

Acute Angle-Closure Glaucoma

China
Santen Pharmaceutical Co., Ltd.

Completed

A Comparative Confirmatory Study of STN1012600 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma, Ocular Hypertension

Japan
ForSight Vision5, Inc.

Completed

Dose-Ranging Study of the Bimatoprost Ocular Insert

Ocular Hypertension | Primary Open-Angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma or Ocular Hypertension

United States
Mario Negri Institute for Pharmacological Research

Completed

Multicentric Observational Study on Quality of Life in Glaucoma

Primary Open-angle Glaucoma

Italy
United States Air Force
Alcon Research

Completed

Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without Preservative

Ocular Hypertension | Open-Angle Glaucoma | Ocular Dryness | Ocular Irritation

United States
Benha University

Recruiting

Effects of Systemic Drugs on Intraocular Pressure

Hypertension | Glaucoma, Angle-Closure | Glaucoma Suspect | Glaucoma Secondary to Drugs, Bilateral

Egypt
Daniel Moore
Pfizer

Terminated

Safety Study of Latanoprost Slow Release Insert (Latanoprost SR)

Primary Open Angle Glaucoma (POAG) | Ocular Hypertension (OHT)

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT

Open Angle Glaucoma or Ocular Hypertension

Singapore
Shire

Completed

Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle Glaucoma

Ocular Hypertension | Primary Open-angle Glaucoma (POAG)

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Long-term Study of DE-117 Ophthalmic Solution Monotherapy and Concomitant Use of DE-117 Ophthalmic Solution With Timolol Ophthalmic Solution in Patients With OAG or OH: RENGE Study

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma or Ocular Hypertension

Japan
Eye Therapies, LLC

Completed

Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension

Glaucoma and Ocular Hypertension

United States
Prince of Songkla University

Completed

The Performances of Spectral Domain Optical Coherence Tomography (OCT) for Distinguishing Glaucomatous Eyes (cirrusOCT)

Normal Population | Glaucoma Patient | Glaucoma Suspect Patient | RNFL Thickness by Location | Macular Thickness by Location

Thailand
Uzoma Chinyei Joan

Recruiting

Comparison of Preserved and Preservative-free Latanoprost 0.005% in Primary Open Angle Glaucoma and Ocular Hypertensive Patients, at Guinness Eye Centre, Lagos.

Effect of Drug

Nigeria
Alcon Research

Terminated

Azopt (Brinzolamide 1.0%) Plus Travatan (Travoprost 0.004%) in Treating Patients With Chronic Angle-Closure Glaucoma (CACG)

Intraocular Pressure

United States
Wolstan and Goldberg Eye Associates

Completed

Investigate, Following Cataract Surgery With IOL in Conjunction With Intracanalicular Dexamethasone Insert

Cataract | Glaucoma, Primary Open Angle

United States
Asian Eye Institute
Ivantis, Inc.

Completed

Hydrus Microstent and Lens Extraction for the Treatment of Primary Angle-Closure Glaucoma

Primary Angle Closure Glaucoma | Primary Angle Closure

Philippines
Quark Pharmaceuticals

Completed

Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG)

Glaucoma, Angle-closure, Primary, Acute

Singapore, United States, Vietnam
University of California, San Diego
National Eye Institute (NEI)

Recruiting

Diagnostic Innovations in Glaucoma Study (DIGS)

Primary Open Angle Glaucoma | Myopia

United States
Cairo University

Active, not recruiting

Combined Phacoemulsification and Diode Laser Therapy in Chronic Angle Closure Glaucoma

Angle Closure Glaucoma

Egypt
Glaukos Corporation

Active, not recruiting

Travoprost Intraocular Implant in Conjunction With Cataract Surgery

Ocular Hypertension | Open Angle Glaucoma

Armenia
Isarna Therapeutics GmbH

Completed

Phase I Dose Escalation Study to Investigate the Safety of ISTH0036 in Subjects With Glaucoma Undergoing Trabeculectomy

Primary Open Angle Glaucoma

Germany
American Society Of Thermalism And Climatology Inc

Unknown

Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion. (GME)

Primary Open Angle Glaucoma | Hypertension Ocular

United States
Glaukos Corporation

Completed

Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (POAG) (SL)

Glaucoma | Glaucoma, Open-Angle | Eye Diseases

Spain, France, Austria, Italy, Armenia, Germany, Greece, Poland, United Kingdom
Sooft Italia

Withdrawn

Effects of Forskolin on Intraocular Pressure in Glaucomatous Patients Under Treatment With Either Beta-blockers or Prostaglandins Eye Drops

Primary Open Angle Glaucoma | Intraocular Pressure

Italy
Santen Inc.

Completed

DE-117 Spectrum 5 Study

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Moorfields Eye Hospital NHS Foundation Trust

Completed

Laser-1st vs Drops-1st for Glaucoma and Ocular Hypertension (LIGHT)

Primary Open Angle Glaucoma | Ocular Hypertension

United Kingdom
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study

Primary Open Angle Glaucoma or Ocular Hypertension

Japan
Maisonneuve-Rosemont Hospital

Recruiting

Visual Outcomes of Vivity in Patients With Well Controlled Glaucoma

Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Canada
Allergan S.A. DE C.V..

Completed

Comparison of Efficacy & Tolerability Between Ganfort vs Krytantek in Mexican Patients With Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Glaucoma Primary Open Angle

Mexico
Technische Universität Dresden

Completed

Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma

Normal Tension Glaucoma | High Tension Glaucoma
Nicox Ophthalmics, Inc.

Recruiting

MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Denali)

Ocular Hypertension | Open Angle Glaucoma

United States, China
iSTAR Medical

Recruiting

MINIject Global Long-Term Follow-up Study (STAR-GLOBAL)

Ocular Hypertension | Open Angle Glaucoma

Germany, Spain, Colombia, France, India, Panama
Theratocular Biotek Co.
Novotech (Australia) Pty Limited

Active, not recruiting

A Study to Investigate the Effect of IOP-lowering With TO-O-1001 Eye Drops in Healthy Subjects and in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

Australia
Ocuphire Pharma, Inc.

Completed

Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucoma

Ocular Hypertension | Open Angle Glaucoma

United States
Ocular Therapeutix, Inc.

Completed

Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT

Ocular Hypertension | Open Angle Glaucoma

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Non Interventional Study With Primary Open Angle Glaucoma and/or Ocular Hypertension Patients Treated With Xalacom® After Failure of Previous Antiglaucoma Therapy.

Glaucoma, Open-angle

Slovakia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucoma

Ocular Hypertension | Glaucoma, Open Angle

Italy, France, Greece, Sweden, Germany
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Xalacom And Combination Of Unfixed Latanoprost And Timolol In Subjects With Open-Angle Glaucoma Or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open Angle

China
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinavia

Ocular Hypertension | Open Angle Glaucoma

Sweden, Norway, Denmark, Finland
Sylentis, S.A.

Completed

SYL040012, Treatment for Open Angle Glaucoma (SYLTAG)

Ocular Hypertension | Open Angle Glaucoma

Spain, Germany, United States, Estonia
Merck Sharp & Dohme LLC

Completed

Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)

Ocular Hypertension | Glaucoma

3

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