Clinical Trials on Glaucoma and Ocular Hypertension

Total 13652 results

Meir Medical Center

Withdrawn

The Effects of Cosopt® Vs Xalacom® on Ocular Hemodynamics and Intraocular Pressure (IOP) in Primary Open-angle Glaucoma (POAG) (Xal-Cos)

Ocular Hypertension | Open-Angle Glaucoma

Israel
Alcon Research

Completed

A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Santen Inc.

Completed

Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Santen Oy

Completed

Pharmacodynamics of Tafluprost 0.0015% Eye Drops: a Comparison Between the Preserved and Unpreserved Formulation

Ocular Hypertension | Open-Angle Glaucoma

Finland, Germany
Santen Pharmaceutical Co., Ltd.

Completed

Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

Japan
Bp Consulting, Inc
Allergan

Completed

Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

Canada
Bp Consulting, Inc

Completed

Comparison of Istalol™ 0.5% QD (Timolol Maleate/Sorbitol Complex, ISTA Pharmaceutical) to Brimonidine Tartrate 0.1% BID as Adjunctive Therapy to Latanoprost 0.005% in Adults With Ocular Hypertension (OHT) or Open-Angle Glaucoma (OAG)

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research

Completed

Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension Patients

Ocular Hypertension | Open-Angle Glaucoma

United States
Padagis LLC

Completed

To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes

Ocular Hypertension | Glaucoma, Open-Angle

United States
Allergan

Completed

Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-Angle

United States, Singapore, Italy, United Kingdom, Egypt, Korea, Republic of, Argentina, Canada, Colombia, Czechia, Germany, Malaysia, New Zealand, South Africa, Turkey
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study to Assess the Efficacy of 3 Months of Latanoprost Treatment in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-angle Glaucoma

Ocular Hypertension | Glaucoma, Open-Angle

France
Allergan

Completed

Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-Angle

Brazil
Allergan

Completed

Safety and Pharmacodynamics Study of AGN-207281 Ophthalmic Solutions Compared With Timolol Ophthalmic Solution or Placebo in Patients With Ocular Hypertension or Primary Open-Angle Glaucoma

Ocular Hypertension | Glaucoma, Open-Angle

United States
Allergan

Completed

A Safety and Efficacy Study of Bimatoprost 0.01% in Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OH)

Ocular Hypertension | Glaucoma, Open-Angle

Korea, Republic of
Allergan

Completed

Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-Angle

United States
Alcon Research

Completed

A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Ocular Hypertension | Glaucoma, Open-Angle

United States
University of California, Los Angeles
Novartis

Recruiting

Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

Glaucoma | Ocular Surface Disease

United States
Glia, LLC

Completed

Amelioration of Adverse Ocular Side Effects of Glaucoma Medications in Glaucoma Patients Using Topical GL101

Ocular Surface Disease

United States
University of Maryland, Baltimore
Aerie Pharmaceuticals

Completed

Measuring the Effects of Rhopressa on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects

Ocular Hypertension | Suspect Glaucoma

United States
Federal University of Rio Grande do Sul

Recruiting

PSLT Compared to Prostaglandin Analogue Eye Drops

Ocular Hypertension | Open Angle Glaucoma

Brazil
PolyActiva Pty Ltd

Completed

Study of a Latanoprost Ocular Implant for Treatment of Open Angle Glaucoma or Ocular Hypertension.

Ocular Hypertension | Open Angle Glaucoma

New Zealand
Aerie Pharmaceuticals

Completed

Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United Kingdom, Spain, Austria, Belgium, Czechia, France, Germany, Hungary, Italy, Latvia, Poland
Sun Pharmaceutical Industries Limited

Withdrawn

A Comparative Study of SPARC's SDP-133 Once Daily and Lumigan in Subjects With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma
Sun Pharma Advanced Research Company Limited

Completed

Evaluation of Safety of SPARC0913 in Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
Sun Pharma Advanced Research Company Limited

Completed

Efficacy and Safety of SPARC0912 and Reference0912 in Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within the United Kingdom

Ocular Hypertension | Open Angle Glaucoma

United Kingdom
Peregrine Ophthalmic

Completed

POLAT-001 Compared to Latanoprost Ophthalmic Solution in Patients With Ocular Hypertension and Open-angle Glaucoma

Glaucoma

United States
Aerie Pharmaceuticals

Completed

Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in Japan

Ocular Hypertension | Open Angle Glaucoma

Japan
Hoffmann-La Roche

Completed

A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-angle

United States
Aerie Pharmaceuticals

Completed

Study Assessing Safety and Efficacy of PG324 Ophthalmic Solution in Patients With Elevated Intraocular Pressure

Ocular Hypertension | Open Angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Study of AR-13324 in Patients With Elevated Intraocular Pressure

Ocular Hypertension | Open Angle Glaucoma

United States
Institut Catala de Retina
Hospital Universitario Ramon y Cajal; Hospital del Mar; Clinica Universidad de... and other collaborators

Completed

Efficacy and Safety of the ExPRESS Implant Versus Deep Sclerectomy in Combined Surgery

Ocular Hypertension | Open Angle Glaucoma

Spain
Aristotle University Of Thessaloniki

Completed

Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressure (CCT-IOP)

Ocular Hypertension | Open Angle Glaucoma

Greece
Santen Pharmaceutical Co., Ltd.

Completed

DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic Solution 0.0015% Plus Timolol Ophthalmic Solution 0.5%

Ocular Hypertension | Open Angle Glaucoma

Japan
Alcon Research

Completed

Travoprost APS Versus Xalatan® in Patient Reported Outcomes and Ocular Surface Health

Ocular Hypertension | Open Angle Glaucoma
Aerie Pharmaceuticals

Completed

A Study Assessing PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components for 28 Days

Ocular Hypertension | Open Angle Glaucoma

United States
Mati Therapeutics Inc.

Completed

Safety and Efficacy of Punctum Plug Delivery System in Subjects With Open-Angle Glaucoma or Ocular Hypertension (CORE)

Ocular Hypertension | Glaucoma

United States
Alcon Research

Completed

A 6-week Safety & Efficacy Study of Combination Intraocular Pressure-lowering Therapy in Patients With Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-angle

United States
Alcon Research

Completed

A 12-Month Study to Evaluate the Efficacy and Safety of Once-Daily Instillation of Combination Glaucoma Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-angle

Belgium
Alcon Research

Completed

Travatan Versus Timoptic in Treating Open-angle Glaucoma or Ocular Hypertension

Glaucoma

United States
Allergan

Recruiting

18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA) (ARGOS)

Ocular Hypertension | Open-angle Glaucoma

United States
Asociación para Evitar la Ceguera en México

Terminated

PASCAL Trabeculoplasty

Open-Angle Glaucoma

Mexico
Aerie Pharmaceuticals

Completed

A Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-12286 in Patients With Elevated Intraocular Pressure for 3 Months

Ocular Hypertension | Open-angle Glaucoma
West Virginia University
University of Pittsburgh; University of Michigan

Withdrawn

African Glaucoma Laser Trial (AGLT)

Open-angle Glaucoma
Glaukos Corporation

Unknown

A Study of the Glaukos Trabecular Micro-bypass Stent in Open Angle Glaucoma Subjects 1 Stent Versus 2

Open-Angle Glaucoma

Spain, Germany, Austria, Turkey
Alcon Research

Completed

24 Hour IOP Lowering Efficacy of AL-3789

Open-angle Glaucoma

United States
Alcon Research

Withdrawn

A Multi-Dose Study With a Treatment for Open-Angle Glaucoma

Open-Angle Glaucoma
Pharmaceutical Research Network

Completed

Lumigan Versus Cosopt

Open-Angle Glaucoma

United States
Pharmaceutical Research Network

Completed

Cosopt Versus Xalatan

Ocular Hypertension | Open-Angle Glaucoma

United States
National Eye Institute (NEI)

Completed

Glaucoma Laser Trial (GLT) Glaucoma Laser Trial Followup Study (GLTFS)

Open-Angle Glaucoma

3

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