Clinical Trials on Glioblastoma, IDH-wildtype in Spain

Total 83 results

Juan M Garcia-Gomez
Hospital Universitario 12 de Octubre; Hospital Clínico Universitario de Valencia

Recruiting

BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological Levels (BIOhabitats)

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Astrocytoma, Grade IV | Glioblastoma, IDH-mutant | Glioblastoma, IDH-wildtype | Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype | Glioblastoma IDH (Isocitrate Dehydrogenase) Mutant

Spain
Hospital San Carlos, Madrid
Asociación de Afectados Por Tumores Cerebrales en España (ASATE)

Recruiting

Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With Glioblastoma (GLINERA)

Glioblastoma | Glioblastoma Multiforme | Radiotherapy; Complications | Glioblastoma, IDH-wildtype | Cancer Brain

Spain
Debiopharm International SA

Recruiting

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Astrocytoma, Grade III | Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype

Spain, United States, Switzerland
Grupo Español de Investigación en Neurooncología

Completed

Neo-adjuvant Treatment With Temozolomide and Bevacizumab Previous to Temozolomide Plus Radiation Plus Bevacizumab Therapy in Unresectable Glioblastoma

Glioblastomas

Spain
Clinica Universidad de Navarra, Universidad de...

Completed

Efficacy & Safety of Autologous Dendritic Cell Vaccination in Glioblastoma Multiforme After Complete Surgical Resection

Glioblastoma Multiforme

Spain
Clinica Universidad de Navarra, Universidad de...

Completed

Neoadjuvant Nivolumab in Glioblastoma (Neo-nivo)

Glioblastoma Multiforme

Spain
Clinica Universidad de Navarra, Universidad de...
DNAtrix, Inc.

Terminated

DNX-2440 Oncolytic Adenovirus for Recurrent Glioblastoma

Glioblastoma | Glioblastoma, Adult

Spain
Hoffmann-La Roche

Completed

A Study of Bevacizumab and Extended Treatment of Temozolomide in Patients With Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme

Spain
Clinica Universidad de Navarra, Universidad de...
DNAtrix, Inc.

Completed

Virus DNX2401 and Temozolomide in Recurrent Glioblastoma (D24GBM)

Glioblastoma Multiforme | Recurrent Tumor

Spain
Mundipharma Research Limited

Active, not recruiting

Study of Tinostamustine for Adjuvant Treatment of Glioblastoma

Glioblastoma Multiforme

Switzerland, Spain
Laminar Pharmaceuticals

Completed

A Study to Evaluate the Safety of LAM561 Added to Standard of Care in Newly-diagnosed Glioblastoma Patients

Glioblastoma (GBM)

Spain
Grupo Español de Investigación en Neurooncología
Pfizer

Completed

Study to Evaluate Safety and Activity of Crizotinib With Temozolomide and Radiotherapy in Newly Diagnosed Glioblastoma

Glioblastoma Multiforme (Grade IV) of Cerebellum

Spain
Genentech, Inc.

Completed

A Study of GDC-0084 in Patients With Progressive or Recurrent High-Grade Glioma

Glioblastoma, Glioma

United States, Spain
Laminar Pharmaceuticals
Laboratory Corporation of America; Northern Institute for Cancer Research,... and other collaborators

Active, not recruiting

LAM561 With RT and TMZ for Adults With Glioblastoma (CLINGLIO)

Glioblastoma Multiforme | Primary Glioblastoma

Spain, Italy, United Kingdom, France, Israel
Novartis Pharmaceuticals

Recruiting

Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma

Newly Diagnosed and Recurrent Glioblastoma

Spain, Israel, Portugal
Forma Therapeutics, Inc.

Completed

A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation

Cohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme) | Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas) | Cohort 3a and 3b: Chondrosarcoma | Cohort 4a and 4b: Intrahepatic... and other conditions

United States, Korea, Republic of, Australia, United Kingdom, Spain, France
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study to Describe the Adherence to the SEOM Algorithm for the Treatment of Hyponatraemia in Spain (ALGA)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Spain
Grupo Español de Investigación en Neurooncología

Completed

Study of Sunitinib Before and During Radiotherapy in Newly Diagnosed Biopsy-only Glioblastoma Patients

Glioblastoma

Spain
Cantex Pharmaceuticals

Recruiting

Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma

Glioblastoma

Spain
Enterome
Covance

Active, not recruiting

First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma (ROSALIE)

Glioblastoma, Adult

United States, Spain, France, Germany
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study on Real-world Use and Outcomes of Patients Treated With Tolvaptan for Hyponatraemia Due to SIADH (SAMPLE)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Germany, Spain
Juan M Garcia-Gomez
Oslo University Hospital; Hospital Clinic of Barcelona; Hospital de Manises; Azienda... and other collaborators

Recruiting

ALBATROSS Study: International Multicenter Study for Prospective Validation of Imaging Biomarkers Calculated at Vascular Habitats of High-grade Gliomas (ALBATROSS)

Astrocytoma, Grade IV

Spain
Juan M Garcia-Gomez
Oslo University Hospital; Hospital Clinic of Barcelona; University of Liege; Hospital... and other collaborators

Completed

Multicentre Validation of How Vascular Biomarkers From Tumor Can Predict the Survival of the Patient With Glioblastoma (ONCOhabitats)

Glioblastoma

Spain
European Organisation for Research and Treatment...
Amgen

Withdrawn

Phase II Trial of Romiplostim for Thrombocytopenia Induced by Lomustine at First Progression of MGMT Promoter-meth Glioblastoma (RIGOLETTO)

First Progression of MGMT Promoter-methylated Glioblastoma

Spain, Switzerland
Novartis Pharmaceuticals

Completed

Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme

Recurrent Glioblastoma Multiforme

United States, Belgium, Australia, Spain, France, Canada
Hospital del Río Hortega
Fundación de Investigación Biomédica - Hospital Universitario de La Princesa and other collaborators

Recruiting

Supramarginal Resection in Glioblastoma Guided by Artificial Intelligence (SupraGlio-AI)

Glioblastoma

Spain
Hospital del Río Hortega

Completed

Assessing the Effectiveness of 2D Non-Navigated Intraoperative Ultrasound in Glioma Surgery (2D-ioUS-Glio)

Glioma | Glioblastoma | Low-grade Glioma | Glioma, Malignant | High-grade Glioma

Spain
InSightec

Recruiting

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients

Glioblastoma | Glioma, Malignant

Italy, Spain
Grupo Español de Investigación en Neurooncología

Completed

Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma (GEINOGLAS)

Glioblastoma

Spain
CarThera

Recruiting

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM (SONOBIRD)

Glioblastoma | GBM | Recurrent Glioblastoma

France, United States, Spain, Belgium, Germany, Italy, Netherlands
Amgen

Completed

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

Glioblastoma or Malignant Glioma

United States, Australia, Netherlands, Germany, Spain, France
Novartis Pharmaceuticals

Recruiting

A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.

Glioblastoma Multiforme | Gastroesophageal Adenocarcinoma | Pancreatic Ductal Adenocarcinoma

Netherlands, Spain, Israel, United States, Switzerland
Celldex Therapeutics

Completed

Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma (ACT IV)

Glioblastoma | Gliosarcoma | Small Cell Glioblastoma | Giant Cell Glioblastoma | Glioblastoma With Oligodendroglial Component

United States, Canada, Australia, Israel, Taiwan, United Kingdom, Belgium, France, Spain, Germany, Austria, Brazil, Colombia, Czechia, Greece, Hungary, India, Italy, Mexico, Netherlands, New Zealand, Peru, Switzerland, Thailand
CNS Pharmaceuticals, Inc.
Worldwide Clinical Trials

Active, not recruiting

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme, Adult

United States, Spain, France, Switzerland, Italy
Immatics Biotechnologies GmbH
BioNTech SE; University Hospital Tuebingen; BCN Peptides; EU-funded GAPVAC Consortium

Completed

GAPVAC Phase I Trial in Newly Diagnosed Glioblastoma Patients

Glioblastoma

Spain, Switzerland, Denmark, Germany, Netherlands
Pfizer

Terminated

Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast Cancer

Advanced Breast Cancer (Parts 1 and 2) | Advanced Pancreatic Cancer (Part 1) | Advanced Colorectal Cancer (Part 1) | Advanced Cholangiocarcinoma (Part 1) | Advanced Glioblastoma Multiforme (Part 1)

United States, Spain, Hong Kong, Belgium, Australia, France
Celgene

Active, not recruiting

CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma

Glioblastoma | Astrocytoma

United States, Spain
Grupo Español de Investigación en Neurooncología
Tilray; Medical Cannabis Bike Tour; Voices Against Brain Cancer

Recruiting

TN-TC11G (THC+CBD) Combination With Temozolomide and Radiotherapy in Patients With Newly-diagnosed Glioblastoma (GEINOCANN)

Glioblastoma

Spain
Novartis Pharmaceuticals

Completed

A Phase 2 Study of BGJ398 in Patients With Recurrent GBM

Recurrent Glioblastoma or Other Glioma Subtypes

Spain, Belgium, United States, Switzerland, Australia, Netherlands
European Organisation for Research and Treatment...
Celgene; Canadian Cancer Trials Group

Completed

A Phase III Trial of With Marizomib in Patients With Newly Diagnosed Glioblastoma (MIRAGE)

Newly Diagnosed Glioblastoma

United States, Belgium, Canada, Spain, Netherlands, France, Switzerland, Germany, Norway, Denmark, Austria, United Kingdom
Novartis Pharmaceuticals

Completed

A Phase I Dose Escalation Study of BKM120 With Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma

Glioblastoma

Australia, Spain, Canada, United States
NovoCure Ltd.

Completed

Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme

United States, Spain, France, Canada, Korea, Republic of, Austria, Israel, Czech Republic, Germany, Italy, Sweden, Switzerland
Boehringer Ingelheim

Recruiting

A Study to Determine How BI 907828 (Brigimadlin) is Taken up in the Tumor (Phase 0) and to Determine the Highest Dose of BI 907828 (Brigimadlin) That Could be Tolerated (Phase 1a) in Combination With Radiation Therapy in People With a Brain Tumor Called Glioblastoma

Glioblastoma

Belgium, Spain, United States
Bristol-Myers Squibb

Active, not recruiting

A Study of the Effectiveness and Safety of Nivolumab Compared to Bevacizumab and of Nivolumab With or Without Ipilimumab in Glioblastoma Patients (CheckMate 143)

Recurrent Glioblastoma

Poland, United Kingdom, United States, Spain, Australia, Germany, Italy, Denmark, Belgium, France, Netherlands, Switzerland
Grupo Español de Investigación en Neurooncología

Completed

Temozolomide 12 Cycles Versus 6 Cycles of Standard First-line Treatment in Patients With Glioblastoma.

Glioblastoma

Spain
AbbVie

Terminated

A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor

Glioblastoma Multiforme | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Colorectal Carcinoma

United States, Spain
Hoffmann-La Roche

Active, not recruiting

A Study Evaluating the Safety, Pharmacokinetic and Anti-tumor Activity of RO7428731 in Participants With Glioblastoma

Glioblastoma

United States, Spain, Australia, Canada, Netherlands, Denmark
Hospital del Río Hortega

Recruiting

Brain Tumor Intraoperative Ultrasound Database (BraTioUS-DB)

Glioma | Glioblastoma | Brain Neoplasms | Brain Cancer | Brain Tumor

Italy, Spain, India
Novartis Pharmaceuticals

Recruiting

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

Glioblastoma

Spain, Switzerland, France, Portugal, United States
Medical Research Council
Merck Sharp & Dohme LLC; Aarhus University Hospital; NCRI Clinical Studies Groups and other collaborators

Unknown

Evaluation Of The Treatment Effectiveness Of Glioblastoma / Gliosarcoma Through The Suppression Of The PI3K/Akt Pathway In Compared With MK-3475

Glioblastoma

United States, Italy, Belgium, Germany, Poland, Russian Federation, Spain, Switzerland, Ukraine, United Kingdom

Clinical Trials on Glioblastoma, IDH-wildtype in Spain

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