Clinical Trials on Glioma Glioblastoma Multiforme

Total 2946 results

National Cancer Institute (NCI)

Terminated

Oxaliplatin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Hemerion Therapeutics

Recruiting

A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of Glioblastoma

Primary Glioblastoma

United States
Aivita Biomedical, Inc.

Not yet recruiting

AV-GBM-1 vs Control as Adjunctive Therapy Following Surgery and RT/TMZ in Newly Diagnosed GBM

Primary Glioblastoma
Assiut University

Not yet recruiting

Automatic Segmentation MRI Cerebral Glioma

Cerebral Glioblastoma
Second Affiliated Hospital, School of Medicine,...
Hangzhou Normal University

Not yet recruiting

Pilot Study of Elemene in Treating Patients With Refractory Glioblastoma

Refractory Glioblastoma

China
Wuerzburg University Hospital

Recruiting

Autologous Dendritic Cells, Metronomic Cyclophosphamide and Checkpoint Blockade in Children With Relapsed HGG

Childhood Glioblastoma

Germany
Kazia Therapeutics Limited

Completed

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Glioblastoma, Adult

United States
Hackensack Meridian Health
NovoCure Ltd.

Completed

NovoTTF-200A and Temozolomide Chemoradiation for Newly Diagnosed Glioblastoma

Glioblastoma, Adult

United States
Novartis Pharmaceuticals

Completed

A Phase 2 Study of BGJ398 in Patients With Recurrent GBM

Recurrent Glioblastoma or Other Glioma Subtypes

Spain, Belgium, United States, Switzerland, Australia, Netherlands
Mayo Clinic
National Cancer Institute (NCI)

Completed

Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their Caregivers

Glioblastoma | Malignant Glioma | WHO Grade III Glioma

United States
Duke University
Monteris Medical

Withdrawn

LITT Palliative Treatment for Patients With Malignant Gliomas

Glioblastoma | Malignant Glioma of Brain

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); BeiGene

Completed

BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations

Recurrent Glioblastoma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | IDH1 Mutation | IDH2 Mutation

United States
National Cancer Institute (NCI)

Recruiting

Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype

Glioma | Glioblastoma | Malignant Glioma | Low Grade Glioma | High Grage Glioma

United States
NRG Oncology
National Cancer Institute (NCI); Radiation Therapy Oncology Group

Active, not recruiting

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States, Canada
National Cancer Institute (NCI)

Completed

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Tipifarnib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Gefitinib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Novartis Pharmaceuticals

Completed

Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors

Metastatic Colorectal Cancer | Gastric Cancer | Advanced Solid Tumors | Metastatic Breast Cancer | Gastroesophageal Junction Cancer | Recurrent Glioblastoma Multiforme | Advanced Pancreatic Adenocarcinoma | Safety | Triple Negative Metastatic Breast Cancer | Dose Escalation | Preliminary Efficacy | Hormone Receptor...

Canada, United Kingdom, Spain, Germany, Italy, Belgium, Australia, United States
Shuttle Pharmaceuticals, Inc.

Not yet recruiting

Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

Glioblastoma, IDH-wildtype

United States
First Affiliated Hospital of Wannan Medical College

Recruiting

The Safety and Effectiveness of NV-A01 in Glioma Patients

Advanced Glioblastoma Patients

China
CANbridge Life Sciences Ltd.

Recruiting

Phase 2 Study of CAN008 in Subjects With GBM

Newly-diagnosed Glioblastoma

China
Swedish Medical Center

Recruiting

Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma

Newly Diagnosed Glioblastoma

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Study of AK105 With Anlotinib and Radiotherapy Adjuvant Therapy in MGMT Unmethylated Newly Diagnosed Glioblastoma.

MGMT-Unmethylated Glioblastoma

China
MimiVax, LLC
Translational Drug Development; Merit

Active, not recruiting

SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE) (SURVIVE)

Newly Diagnosed Glioblastoma

United States
European Organisation for Research and Treatment...
Celgene; Canadian Cancer Trials Group

Completed

A Phase III Trial of With Marizomib in Patients With Newly Diagnosed Glioblastoma (MIRAGE)

Newly Diagnosed Glioblastoma

United States, Belgium, Canada, Spain, Netherlands, France, Switzerland, Germany, Norway, Denmark, Austria, United Kingdom
Basilea Pharmaceutica
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Terminated

Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Glioblastoma | MGMT-Unmethylated Glioblastoma

United States
Genexine, Inc.

Completed

Dose-escalation Study to Evaluate the Safety and Tolerability of GX-I7 in Patients With Glioblastoma (GBM)

Newly Diagnosed Glioblastoma

Korea, Republic of
Centre Georges Francois Leclerc
Pfizer; Hoffmann-La Roche; National Cancer Institute, France; UNICANCER; Association...

Completed

Evaluation of the Irinotecan/Bevacizumab Association for Naive Unresectable Glioblastoma (TemAvIr)

Naive Unresectable Glioblastoma

France
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Not yet recruiting

Retifanlimab With Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

Recurrent Glioblastoma | Recurrent WHO Grade 4 Glioma

United States
Beijing Sanbo Brain Hospital

Recruiting

Study of Recombinant Human Endostatin Combined With Temozolomide and Irinotecan in Recurrent Gliomas

Glioblastoma, Recurrent | Lower Grade Glioma, Recurrent

China
Sidney Kimmel Cancer Center at Thomas Jefferson...

Recruiting

Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma

Glioblastoma | WHO Grade III Glioma | WHO Grade II Glioma

United States
Spectrum Pharmaceuticals, Inc

Terminated

A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies

Breast Cancer | Colorectal Cancer | Solid Tumor | Glioblastome Multiforme

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma

Glioblastoma | Malignant Glioma | WHO Grade III Glioma | Recurrent Glioma | Refractory Glioma

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable Glioblastoma

Glioblastoma | Recurrent Glioblastoma | Resectable Glioblastoma

United States
Washington University School of Medicine
Incyte Corporation; PapiVax Biotech, Inc.

Recruiting

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Unmethylated Glioblastoma

United States
Amsterdam UMC, location VUmc

Recruiting

Function and Composition of Regulatory B Cells in Participants With Glioblastoma (GBMdexaB)

Glioblastoma, Adult

Netherlands
Asan Medical Center

Recruiting

Advanced MR Imaging as Predictor of Treatment Response in Newly Diagnosed Glioblastomas

Adult Glioblastoma

Korea, Republic of
Enterome
Covance

Active, not recruiting

First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma (ROSALIE)

Glioblastoma, Adult

United States, Spain, France, Germany
Centre Georges Francois Leclerc

Active, not recruiting

Study Evaluating the Efficacy of Radiotherapy With SIB-IMRT, Associated With Temozolomide in Glioblastomas (Glio-SIB-Up)

Glioblastoma, Adult

France
Laminar Pharmaceuticals

Completed

A Study to Evaluate the Safety of LAM561 Added to Standard of Care in Newly-diagnosed Glioblastoma Patients

Glioblastoma (GBM)

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

FDG PET Imaging in Diagnosing Patients With Glioblastoma

Brain Glioblastoma

United States
University Hospital Heidelberg

Completed

Carbon Ion Radiotherapy for Primary Glioblastoma (CLEOPATRA)

Primary Glioblastoma

Germany
Centre Jean Perrin
National Cancer Institute, France; ARC Foundation for Cancer Research

Completed

Study of LY2228820 With Radiotherapy Plus Concomitant TMZ in the Treatment of Newly Diagnosed Glioblastoma (GLYRad)

Adult Glioblastoma

France
SCRI Development Innovations, LLC
Novartis

Completed

INC280 Combined With Bevacizumab in Patients With Glioblastoma Multiforme

Renal Cell Carcinoma | Colorectal Cancer | Glioblastoma Multiforme | Gliosarcoma

United States
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Dimethyl Fumarate, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Adult Brain Glioblastoma

United States
Fondazione Policlinico Universitario Agostino Gemelli...
Catholic University of the Sacred Heart; Heinrich-Heine University, Duesseldorf and other collaborators

Recruiting

Grafts of GSCs Into Brain Organoids for Testing Anti-invasion Drugs (2253)

Glioblastoma | Glioma, Malignant

Italy
Sanofi

Completed

Study of the Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitor BSI-201 in Patients With Newly Diagnosed Malignant Glioma

Glioblastoma

United States
University of Oklahoma
GlaxoSmithKline

Terminated

PARP Inhibition for Gliomas (PI-4G or π4g) (OU-SCC-PI-4G)

Recurrent Glioblastoma | Recurrent Glioma | Recurrent Astrocytoma | Recurrent Oligodendroglioma

United States
University of Florida
NovoCure Ltd.

Active, not recruiting

Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP) (2-THE-TOP)

Glioblastoma | Glioblastoma, WHO Grade IV

United States
Exelixis

Completed

Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States

Clinical Trials on Glioma Glioblastoma Multiforme

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CROs in Angola

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