Clinical Trials on Glioma, Sarcomatous

Total 2969 results

Institut Curie

Terminated

AsiDNA Children, Adolescents and Young Adults (AsiDNA)

Recurrent High-grade Glioma

France
Center Trials & Treatment Europe

Completed

Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma

Gliosarcoma | Glioma, Malignant | Astrocytoma of Brain

Georgia, Bosnia and Herzegovina, Bulgaria
Odense University Hospital
Novo Nordisk A/S; Rigshospitalet, Denmark; Danish Cancer Society; Region of Southern...

Completed

Treatment Decision-making in Patients With Recurrent High-grade Glioma

Malignant Glioma | Life Experiences

Denmark
Rigshospitalet, Denmark
Danish Center for Interventional Research in Radiation Oncology (CIRRO)

Terminated

Image Guided Reirradiation of High-grade Glioma

Glioblastoma | Malignant Glioma

Sweden, Denmark
Nanfang Hospital of Southern Medical University
The First Affiliated Hospital of Nanchang University; Xiangya Hospital of Central... and other collaborators

Unknown

Treatment Response and Prognosis in Glioma Patients: Q Cell and Its Biological Characteristics

Glioblastoma | Malignant Glioma

China
Children's Hospital Los Angeles
Dana-Farber Cancer Institute

Active, not recruiting

Study of MEK162 for Children With Low-Grade Gliomas

Soft Tissue Neoplasms | Low-Grade Gliomas | Malignant Neoplasms, Brain

United States
M.D. Anderson Cancer Center

Recruiting

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Glioblastoma | Anaplastic Oligoastrocytoma | Oligoastrocytoma | Oligodendroglioma | Anaplastic Oligodendroglioma | WHO Grade III Glioma | Diffuse Astrocytoma, IDH-Wildtype | WHO Grade II Glioma | Anaplastic Astrocytoma, IDH-Wildtype

United States
Children's National Research Institute

Recruiting

Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

Diffuse Intrinsic Pontine Glioma | Brainstem Glioma

United States
St. Jude Children's Research Hospital

Completed

Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)

Diffuse Intrinsic Pontine Glioma | High-grade Glioma

United States
Burzynski Research Institute

Completed

Antineoplaston Therapy in Treating Children With Visual Pathway Glioma (VPG)

Visual Pathway Glioma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); BeiGene

Completed

BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations

Recurrent Glioblastoma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | IDH1 Mutation | IDH2 Mutation

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Atypical Teratoid/Rhabdoid Tumor | Refractory Diffuse Intrinsic Pontine Glioma | CNS Embryonal Tumor, Not Otherwise Specified

United States
Alpheus Medical, Inc.

Active, not recruiting

Study to Evaluate 5-ALA Combined With CV01 Delivery of Ultrasound in Recurrent High Grade Glioma

High Grade Glioma

United States
University Hospital, Montpellier

Completed

Longitudinal MRI Assessment in Patients With Diffuse Low-grade Gliomas (SPECIFY)

Low-grade Glioma

France
Immunitor LLC

Unknown

V-Boost Immunotherapy in Glioblastoma Multiforme Brain Cancer (GBM)

Glioblastoma Multiforme | Glioma of Brain

Mongolia
St. Olavs Hospital
Norwegian University of Science and Technology

Recruiting

68Ga/177Lu-PSMA Theranostics in Recurrent Grade 3 and Grade 4 Glioma

High Grade Glioma

Norway
Shanghai 10th People's Hospital
Hangzhou NeoVax Biotechnology Co. LTD

Recruiting

Neoantigens Phase I Trial in Newly Diagnosed Glioblastoma Patients

Glioma, Malignant | Antigen-specific Vaccines | Individualized Treatment

China
Central Hospital, Nancy, France

Recruiting

Contribution of Cerebral 18F-DOPA PET-CT Scan in High-grade Recurrent Gliomas (DORA)

High Grade Glioma

France
Nader Sanai
InSightec; SonALAsense, Inc.; Barrow Neurological Institute; Ivy Brain Tumor Center

Recruiting

Study of Sonodynamic Therapy in Participants With Recurrent High-Grade Glioma

High Grade Glioma

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

First-line Chemotherapy With Temozolomide Alone for Non-enhancing Adult Brainstem Gliomas, With a Diffuse Subtype and Showing Clinical and/or Radiological Infiltrative Pattern of Progression (TEMOTRAD01)

Adult Brainstem Glioma

France
Celgene
Triphase

Completed

Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab

Glioblastoma | Malignant Glioma

United States, Canada
Children's Cancer Hospital Egypt 57357

Completed

Prospective Trial of Two Hypofractionated Radiotherapy Regimens Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children

Pediatric Brain Stem Glioma

Egypt
Celgene
Triphase

Completed

Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer

Glioblastoma | Malignant Glioma

United States, Canada, Switzerland
The First People's Hospital of Lianyungang
The Affiliated Hospital of Qingdao University; Shandong Cancer Hospital and... and other collaborators

Unknown

Apatinib and Irinotecan in Treating Patients With Recurrent High-grade Glioma

High-grade Glioma

China
Eudocia Quant Lee, MD
University of California, San Diego; Beth Israel Deaconess Medical Center; Dartmouth-Hitchcock... and other collaborators

Completed

A Randomized Placebo-Controlled Trial of Armodafinil (Nuvigil) for Fatigue in Patients With Malignant Gliomas

Malignant Glioma

United States
Oncolytics Biotech

Completed

Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomas

Malignant Glioma

United States
National Cancer Institute (NCI)

Recruiting

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Glioblastoma | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Astrocytoma, Not Otherwise Specified | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Glioblastoma, Not Otherwise Specified

United States, Australia, Canada, New Zealand
Thomas Hope

Completed

Fluoroethyltyrosine for Evaluation of Intracranial Neoplasms (UC-GlioFET)

Recurrent Glioblastoma | Recurrent WHO Grade III Glioma | Low Grade Glioma | Intracranial Neoplasm | Recurrent World Health Organization (WHO) Grade II Glioma

United States
Dana-Farber Cancer Institute
Celgene; Secura Bio, Inc.

Terminated

Phase I Study of Marizomib + Panobinostat for Children With DIPG (DIPG)

Pediatric Cancer | Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor | Diffuse Glioma | Pediatric Brainstem Glioma | Pediatric Brainstem Gliosarcoma, Recurrent

United States
Weill Medical College of Cornell University

Terminated

Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22

Glioblastoma Multiforme | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Brain Stem Glioma | Pilomyxoid Astrocytoma | Glioma of Brainstem | Fibrillary Astrocytoma of Brain | Mixed Oligodendroglioma-Astrocytoma

United States
Second Affiliated Hospital of Nanchang University
Wuhan University; Renmin Hospital of Wuhan University

Recruiting

Combing a Deep Learning-Based Radiomics With Liquid Biopsy for Preoperative and Non-invasive Diagnosis of Glioma

Liquid Biopsy | Deep Learning | Glioma (Diagnosis)

China
University of Pennsylvania
University of California, San Francisco

Terminated

Autologous T Cells Redirected to EGFRVIII-With a Chimeric Antigen Receptor in Patients With EGFRVIII+ Glioblastoma

Patients With Residual or Reccurent EGFRvIII+ Glioma

United States
Chembrain LTD
University of Oulu; Jyväskylä Central Hospital; Apollo Hospital, New Delhi, India

Active, not recruiting

The Efficacy and Safety of Brain-targeting Immune Cells (EGFRvIII-CAR T Cells) in Treating Patients With Leptomeningeal Disease From Glioblastoma. Administering Patients EGFRvIII -CAR T Cells May Help to Recognize and Destroy Brain Tumor Cells in Patients (CARTREMENDOUS)

Glioblastoma | Glioblastoma Multiforme | Glioma, Malignant

Finland, India
MediGene
National Cancer Institute (NCI)

Completed

G207 Followed by Radiation Therapy in Malignant Glioma

Malignant Glioma

United States
University of Alabama at Birmingham

Not yet recruiting

Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)

Recurrent Malignant Glioma | Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain | Gliosarcoma of Brain

United States
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial

Meningioma | Low Grade Glioma | Malignant Brain Neoplasm | Malignant Brain Glioma

United States
Northwell Health

Recruiting

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme, Adult

United States
Benedetto Falsini

Recruiting

Safety and Efficacy of the PAINLESS Nerve Growth Factor CHF6467 in Optic Pathway Glioma (OPG) (NGF-OPG)

Optic Pathway Glioma

Italy
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); NovoCure Ltd.; American Lebanese Syrian Associated...

Recruiting

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

Malignant Glioma | Ependymoma | Diffuse Intrinsic Pontine Glioma

United States
Clinica Universidad de Navarra, Universidad de...
DNAtrix, Inc.; Alcyone Lifesciences, Inc.

Completed

Oncolytic Adenovirus, DNX-2401, for Naive Diffuse Intrinsic Pontine Gliomas

Neoadjuvant Therapy | Brainstem Glioma

Spain
National Cancer Institute (NCI)

Completed

Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Solving Kids' Cancer

Completed

Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).

Diffuse Intrinsic Pontine Glioma (DIPG)

United States
Bambino Gesù Hospital and Research Institute

Recruiting

GD2-CAR T Cells for Pediatric Brain Tumours

High Grade Glioma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Embryonal Tumor | Brain Tumor Adult | Brain Tumor, Pediatric

Italy
University of Florida
NovoCure Ltd.

Terminated

TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma

Glioblastoma | Glioblastoma Multiforme | Malignant Glioma | GBM

United States
Gary Archer Ph.D.
Bristol-Myers Squibb; Duke Cancer Institute

Completed

Nivolumab With DC Vaccines for Recurrent Brain Tumors (AVERT)

Glioblastoma | Astrocytoma | Malignant Glioma

United States
National Cancer Institute (NCI)

Withdrawn

A Pilot Study Evaluating 18F-L-Thymidine (FLT) PET Imaging in Children With Gliomas

Astrocytoma | Glioblastoma Multiforme | Ependymoma | PNET | Brainstem Glioma
Katy Peters
Amgen

Completed

AMG 102 and Avastin for Recurrent Malignant Glioma

Glioblastoma Multiforme | Gliosarcoma

United States
University of Zurich

Terminated

Hypertension Monitoring in Glioma Patients Treated With Bevacizumab

Glioma Patients

Switzerland
Armando Santoro, MD
GlaxoSmithKline; Istituto Clinico Humanitas

Not yet recruiting

Niraparib and Temozolomide in Patients Glioblastoma (ONC-2022-001)

Glioma, Malignant

Italy
Duke University

Not yet recruiting

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252 (PuMP)

Recurrent High Grade Glioma

Clinical Trials on Glioma, Sarcomatous

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