Clinical Trials on HCV Genotype 1b

Total 9556 results

University of Southern Denmark
Odense University Hospital

Terminated

Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes

Cytochrome P450 Phenotype and Genotype Metrics

Denmark
Gilead Sciences

Completed

GS-5885, GS-9451, Tegobuvir and Ribavirin (RBV) in Interferon Ineligible or Intolerant Subjects With Chronic Genotype 1a or 1b Hepatitis C Virus (HCV) Infection

Chronic Genotype 1a or 1b HCV Infection

United States, Canada, Puerto Rico
Bristol-Myers Squibb

Completed

Study of the Safety & PK of INX-08189 in Chronically-infected HCV, Treatment-naïve Subjects

HCV (Genotype 1)

United States, Puerto Rico
University Hospital, Strasbourg, France

Unknown

Clinical Investigation of Erlotinib as an HCV Entry Inhibitor

Chronic Hepatitis C Infection | HCV Genotype 1b

France
Gilead Sciences

Completed

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Treatment-Naive and Treatment-Experienced Subjects With Chronic Genotype 4 or 5 HCV Infection

Chronic Genotype 4 HCV | Chronic Genotype 5 HCV

France
R-Pharm
Almedis

Completed

Efficacy and Safety of All-Oral Combination of Narlaprevir/Ritonavir and Daclatasvir in Treatment-Naїve Patients With Chronic Hepatitis C Genotype 1b

Chronic Hepatitis C Genotype 1b

Russian Federation
Chinese Academy of Sciences
LanZhou University

Completed

Cytochrome P450 2C19 Variant is Related to Pharmacokinetics of Glipizide Extended Release Tablet in Chinese Subjects

Pharmacokinetic | Genotype

China
Assistance Publique - Hôpitaux de Paris
Gilead Sciences

Terminated

HCV, HBV, HIV Testing During Consultation With Anesthesiologist (SAHARA)

Hiv | HBV | HCV

France
Biohaven Pharmaceuticals, Inc.

Active, not recruiting

Trial in Adult Subjects With Spinocerebellar Ataxia

Spinocerebellar Ataxias | Spinocerebellar Ataxia Genotype Type 1 | Spinocerebellar Ataxia Genotype Type 2 | Spinocerebellar Ataxia Genotype Type 3 | Spinocerebellar Ataxia Genotype Type 6 | Spinocerebellar Ataxia Genotype Type 7 | Spinocerebellar Ataxia Genotype Type 8 | Spinocerebellar Ataxia Genotype...

United States
Matthias Schwab

Completed

Open Label Study for the Functional Characterization of Drug Metabolism and Transport (IKP243)

Genotype-related Drug Metabolism

Germany
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.

Completed

A Phase III Study to Evaluate Efficacy and Safety of TG-2349 in Combination With DAG181 and RBV for HCV Type I Patients

Cirrhosis | Chronic Hepatics C Virus (HCV) Genotype 1 | Non-Cirrhotic | Treatment naïve

China
Samsung Medical Center

Unknown

Isoniazid Dosage Prediction Model Development

NAT2 Genotype

Korea, Republic of
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
Peking University People's Hospital

Completed

To Evaluate Efficacy and Safety in TG-2349 Combination With DAG181 (± Ribavirin) in HCV Genotype I Infected Patients

Cirrhosis | Chronic Hepatics C Virus (HCV) Genotype 1 | Non-Cirrhotic | Treatment naïve

China
Sequenom, Inc.
NAFTNet

Completed

A Noninvasive Test for Fetal RHD Genotype (NAFTnet RHD)

Rhesus D Genotype

United States, Canada
Sequenom, Inc.
Sequenom Center for Molecular Medicine

Completed

Evaluation of a Noninvasive Fetal RHD Genotyping Test (IRIS)

Rhesus D Genotype

United States
Bispebjerg Hospital
University of Copenhagen; Duke University; The Ministry of Science, Technology... and other collaborators

Completed

Metabolism of Methylphenidate and Enalapril Based on CES1 Genotype

Carboxylesterase 1 (CES1) Genotype | CES1 Activity

Denmark
California Pacific Medical Center Research Institute
Children's Mercy Hospital Kansas City

Withdrawn

The Impact of Genetic Variation in CYP2D6 on the Pharmacokinetics and Pharmacodynamics of Methamphetamine

Methamphetamine Metabolism, CYP2D6 Genotype

United States
National Research Council, Spain
IMDEA Food; CEIP (primary school) Jara Carrillo (Alcantarilla, Murcia, Spain); IES (secondary school) Alcántara (Alcantarilla, Murcia, Spain)

Completed

Genotype, Metabotype and Diet in a Cohort of Children and Adolescents From the Southeast of Spain. (PolyMicroBio)

Genotype, Metabotype and Dietary Habits

Spain
Inje University

Completed

STUDY The Effect of HNF-4A G60D Variant on the In VIVO CYP2D6 Activity By Tolterodine Pharmacokinetic Study (HNF4a)

Healthy Subjects | Genotype Guided(HNF4a)
University of Southern Denmark

Completed

Impact of CYP2C19*17 on the Pharmacokinetics of Proguanil and Clopidogrel

CYP2C19 Genotypes

Denmark
National Taiwan University Hospital

Not yet recruiting

UGT1A1 Genotyping in Taiwanese Cancer Patients

The Influence of the UGT1A1 Genotype
Bispebjerg Hospital
University of Copenhagen; Duke University; The Ministry of Science, Technology... and other collaborators

Completed

Impact of CES1 Genotype on Metabolism of Methylphenidate

Carboxylesterase 1 (CES1) Genotype | CES1 Activity

Denmark
Northwell Health

Terminated

1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain

High Risk MC4R Genotype | Low Risk MC4R Genotype | One Week or Less Antipsychotic Lifetime Exposure

United States
Henan Cancer Hospital

Recruiting

The Maintenance Treatment of "ITIVA" in AML Patients

Acute Myeloid Leukemia | Thalidomide | Maintenance Treatment | Minor Residue Disease | Interferon-α-1b | Interleukin-2 | Venentoclax | Azacitidine

China
Indiana University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Evaluate Pharmacokinetics and Safety of Slow Release DHEA (DHEA)

Asthma | Genotype

United States
Institute Of Cardiology & Internal Diseases, Kazakhstan
Merck Sharp & Dohme LLC; Synergy Research Group

Unknown

Open-Label Efficacy and Safety Study of the Elbasvir/ Grazoprevir Fixed Dose Combination Patients With Chronic HCV GT1b

Metabolic Syndrome | Fibrosis, Liver | Cirrhoses, Liver | Chronic Hepatitis C Genotype 1B

Kazakhstan
Pfizer

Terminated

Pre-Operative Study of PF-4691502 With Letrozole Compared To Letrozole Alone In Patients With Early Breast Cancer

Early Breast Cancer (Phase 2) | Advanced Breast Cancer (Phase 1b)

Spain, Sweden, Italy, Belgium
Dr.Waleed Samir

Unknown

Impact of IL-28B rs12979860 and rs4803217 Gene Polymorphisms Associated With miRNAs Deregulation on HCV-related Hepatocellular Carcinoma

HCV Infection ( Genotype 4)

Egypt
AbbVie

Completed

Coadministration of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) With Ribavirin (RBV) in Adults With Genotype 4 (GT4) Hepatitis C Virus (HCV) in Egypt

HCV | Hepatitis C Infection | Genotype 4
Hacettepe University

Completed

Can Modified Coronally Advanced Tunnel be an Alternative in Gingival Phenotype Modification?

Gingival Phenotype

Turkey
Krishnadevaraya College of Dental Sciences & Hospital

Not yet recruiting

Comparison of Microneedling and CTG for Gingival Augmentation- A RCT

Gingival Phenotype
Central Hospital, Nancy, France

Recruiting

FAMILY INHERITANCE, GENE-GENE AND GENE-ENVIRONMENT INTERACTIONS IN THE FIELD OF CARDIOVASCULAR AND RENAL DISEASES. Fifth Visit of the STANISLAS Cohort

Cardiovascular Diseases | Risk Factors | Nutrition | Cohort Studies | Genotype

France
London School of Hygiene and Tropical Medicine
University of Ulster

Terminated

Pilot Evaluation of the Effect of Riboflavin Supplementation on Blood Pressure and Possible Effect Modification by the MTHFR C677T Genotype (RiboBP)

High Blood Pressure | MTHFR C677T Genotype

Gambia
University College London Hospitals

Completed

Analysis of the Duration of Combination Therapy That is Necessary for HCV Genotype 1 Eradication

Chronic Hepatitis C, HCV Genotype 1

United Kingdom
National Eye Institute (NEI)

Recruiting

Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With Evaluation of the ABCA4 Gene

Retinal Disease | Genotype

United States
National Institutes of Health Clinical Center (CC)
Bristol-Myers Squibb; National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability, and Efficacy of Asunaprevir and Daclatasvir in Subjects Coinfected With HIV-HCV

HIV-HCV

United States
Korea University Anam Hospital
National Cancer Center, Korea; Korean Breast Cancer Study Group

Unknown

CYP2D6 Genotype on the Clinical Effect of Tamoxifen (ASTRRA-CYP2D6)

Breast Neoplasms | Genotype | Tamoxifen | CYP2D6

Korea, Republic of
Tel-Aviv Sourasky Medical Center
Merck Sharp & Dohme LLC

Unknown

the Effect of Grazoprevir/Elbasvir and TACE vs. TACE Alone in Prolonging Survival of Patients With Non-resectable HCV Associated HCC. (ZEPATIER)

HCV, HCC
Herlev Hospital

Completed

Study of the Correlation Between Specific Genes and Cognitive Dysfunction After Surgery

Cognitive Impairment | Genotype

Denmark
Assistance Publique Hopitaux De Marseille

Unknown

Analysis of the Impact of HCV Treatment by Last Generation Direct Antiviral Agents (DAA) on Antiviral Immunity and HIV DNA Reservoir in Coinfected HIV-HCV Patients (HCURE)

HIV Associated HCV

France
Children's Mercy Hospital Kansas City
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Biomarkers of CYP2D6 and CYP3A4 Variability in Pediatrics

Drug Metabolism Phenotype

United States
Misr International University

Recruiting

Assessment of Gingival Thickness Using Colored Periodontal Probe

Gingival Phenotype

Egypt
AbbVie

Completed

Ombitasvir/ABT-450/Ritonavir and Dasabuvir Therapy With Low Dose Ribavirin (RBV), Full Dose RBV or RBV Add-On in Treatment Naive Genotype 1a Hepatitis C Virus Infected Adults

Chronic Hepatitis C | Hepatitis C (HCV) | Hepatitis C Genotype 1a
AbbVie (prior sponsor, Abbott)

Completed

ABT-450 With Ritonavir and ABT-267 and/or ABT-333 With and Without Ribavirin in Genotype 1 Hepatitis C Virus Infected Patients

Chronic Hepatitis C | Hepatitis C Genotype 1 | Hepatitis C (HCV)

United States, Australia, Canada, France, Germany, New Zealand, Puerto Rico, Spain, United Kingdom
AbbVie

Completed

Ombitasvir/ABT-450 (Paritaprevir)/Ritonavir With Dasabuvir and Ribavirin (RBV) in Treatment Naive and Treatment Experienced Genotype 1a Hepatitis C Virus Infected Adults

Chronic Hepatitis C | Hepatitis C (HCV) | Hepatitis C Genotype 1a
Seoul National University Hospital

Completed

Clinical Trial to Evaluate the Influence of Genotype on the Pharmacokinetics/Pharmacodynamics of Clopidogrel

Influence of Genotype of Drug Metabolizing Enzyme or Transporter on the Pharmacokinetics/Pharmacodynamics of Clopidogrel | Influence of Aspirin on the Pharmacokinetics/Pharmacodynamics of Clopidogrel

Korea, Republic of
AbbVie

Completed

Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir Co-Administered With Sofosbuvir With and Without Ribavirin in Treatment-Naive HCV Genotype 1-Infected Adults

Chronic Hepatitis C Virus (HCV Infection Genotype 1)
AbbVie (prior sponsor, Abbott)

Completed

A Randomized Study to Evaluate the Safety, Tolerability and Antiviral Activity of ABT-450, ABT-333 and ABT-072 (Champion2)

Hepatitis C | Chronic Hepatitis C Infection | HCV | Hepatitis C Genotype 1

United States, Puerto Rico
Peking University

Recruiting

Targeted Treatment Plus Tislelizumab and HAIC for Advanced CRCLM Failed From Standard Systemic Treatment

Liver Metastasis Colon Cancer | MSS | ctDNA Genotype | Failed From Standard Treatment

China
Merck Sharp & Dohme LLC

Completed

Quality of Life During Treatment of Chronic Hepatitis C (P05278/MK-4031-336) (VIDA)

Hepatitis C, Chronic | Genotype 1 | HCV-1

Clinical Trials on HCV Genotype 1b

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Tunisia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations