Clinical Trials on HER2 Positive in France

Total 634 results

Melinta Therapeutics, LLC

Recruiting

Open-Label, Dose-Finding, Pharmacokinetics, Safety and Tolerability Study of Oritavancin in Pediatric Patients With Suspected or Confirmed Bacterial Infections

Gram Positive Bacterial Infections

United States
Centre Hospitalier Universitaire de Nice

Unknown

Role of the NLRP3 Inflammasome in Escherichia Coli and Staphylococcus Aureus Bacteria (NLRP3-Bact)

Staphylococcus Aureus | Escherichia Coli Infections

France
Arno Therapeutics

Unknown

Phase 1-2 Study of Onapristone in Patients With Progesterone Receptor Expressing Cancers

Progesterone Receptor Positive Tumor: Max 1 Line of Prior Chemotherapy, no Prior Hormone Therapy

France
Department of Clinical Research and Innovation

Unknown

Streptococcus Pneumoniae Nasopharyngeal Carriage

Nursery

France
Eisai Inc.

Completed

Trial of H3B-6545, in Women With Locally Advanced or Metastatic Estrogen Receptor-positive, HER2 Negative Breast Cancer

Breast Cancer | Breast Neoplasms | Cancer, Breast | Breast Cancer Female | Estrogen Receptor Positive Tumor | Breast Adenocarcinoma | ER Positive | Estrogen-receptor Positive Breast Cancer

France, United Kingdom, United States
Puma Biotechnology, Inc.

Completed

A Study of Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+ Metastatic Breast Cancer Who Have Received Two or More Prior HER2 Directed Regimens in the Metastatic Setting (NALA)

HER2+ Metastatic Breast Cancer (MBC)

United States, Canada, Spain, Singapore, Korea, Republic of, Taiwan, United Kingdom, Israel, Australia, Japan, Hong Kong, Finland, Ireland, Italy, France, Portugal, Germany, Sweden, Belgium, Brazil, Czechia, Switzerland, Argentina, Au... and more
Assistance Publique - Hôpitaux de Paris
Advanz Pharma; Centre Hospitalier de Perigueux; CHU de Nantes; Centre National...

Recruiting

Dalbavancin Versus Standard Antibiotic Therapy for Catheter-related Bloodstream Infections Due to Staphylococcus Aureus (DALICATH)

Staphylococcus Aureus Infection | Catheter Bacteremia

France
Institut National de la Santé Et de la Recherche...

Recruiting

Serotype Distribution in Hospitalized Adult With Pneumococcal Community Acquired Pneumonia in France (CAP'Hospi)

Pneumonia | Pneumococcal Infections | Community-acquired Pneumonia

France
Centre Hospitalier Universitaire de Nice

Recruiting

Prevention of Missed Opportunities for HIV Diagnosis by Promoting HIV Testing of Patients With Pneumococcal Pneumonia at Nice University Hospital (PneumoVIH) (PneumoVIH)

Pneumonia, Pneumococcal | Hiv

France
Hospices Civils de Lyon

Withdrawn

Effectiveness of Intravenous Immunoglobulins (IVIG) in Toxic Shock Syndromes in Children (IGHN2)

Staphylococcal Infection | Streptococcal Infection

France
Centre Hospitalier Universitaire Dijon

Completed

Identification and Quantification of Immune Response Induced by Hyaluronidase and Other Factors of Virulence of Invasive Human Infections of Streptococcus Pneumoniae (Hyalo strepto)

Invasive Pneumococcic

France
University Hospital, Angers

Completed

Vascular Dysfunction and Antiangiogenic Therapy (DYVA-AAGG)

Solid Tumor | Endothelial Dysfunction | Tumor Angiogenesis | CML (Chronic Myelogenous Leukemia)

France
Hospices Civils de Lyon

Unknown

The Value of 99mTc-Leukoscan® Scintigraphy in the Diagnosis of Infectious Endocarditis on Surgical Materials (PLEIM)

Endocarditis

France
Astellas Pharma Europe B.V.

Terminated

To Determine the Feasibility of a Fidaxomicin Study in Neonates and to Assess C. Difficile (Clostridium Difficile) Involvement in the Pathogenesis (DAISY)

Clostridium Difficile

France, Germany, Netherlands, Spain
University Hospital, Clermont-Ferrand

Completed

Effect of PEEP and Trendelenburg on Ultrasound Size of Internal Jugular and Subclavian Veins (PEEPUS)

Ventilated Patient in Intensive Care | Management of the Expiratory End-expiratory Pressure (PEEP) and Body Position

France
Institut Bergonié

Recruiting

Regional Central Database Recording of Chronic Myeloid Leukemia (LMC)

Chronic Myeloid Leukemia

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Role of Bile Acids and Microbiota in Clostridioides Difficile Infection in Ulcerative Colitis (ABRICO)

Ulcerative Colitis

France
University Hospital, Bordeaux

Recruiting

CML Pediatric ITK Response According to Molecular Identification at Diagnosis (CML Piramid)

Chronic Myeloid Leukemia

France
University Hospital, Grenoble

Unknown

Risk Factors for Staphylococcus Aureus Surgical Site Infections in Orthopedic and Trauma Surgery (ISO)

Staphylococcus Aureus | Surgical Wound Infection | Orthopedic Disorder | Traumatology

France
Hospices Civils de Lyon

Completed

Teicoplanin-based Antimicrobial Therapy in Staphylococcus Aureus Bone and Joint Infection: Tolerance, Efficacy and Experience With Subcutaneous Administration

Staphylococcus Aureus | Bone and Joint Infection | Teicoplanin-based Antimicrobial Therapy

France
Centre Hospitalier Universitaire de Besancon

Completed

Study of Predictive Immunological Parameters of Molecular Complete Remission in Patients With Chronic Myelogenous Leukemia in Chronic Phase and Treated With Tyrosine Kinase Inhibitor (PAMIR01)

Chronic Leukemia

France
University Hospital, Toulouse
Institut National de la Santé Et de la Recherche Médicale, France

Active, not recruiting

Deciphering the Role of Circular RNAs in ALKpositive Anaplastic Large-cell Lymphoma (CIRComa)

ALK-Positive Anaplastic Large Cell Lymphoma

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Echocardiography Versus no Echocardiography in S. Aureus Bacteraemia and VIRSTA Score < 3 (VIRSTA-VAL)

Bacteremia | Staphylococcus Aureus | Infective Endocarditis

France
Centre de Recherches et d'Etude sur la Pathologie...

Completed

Dual Therapy Etravirine + Raltegravir by Once Daily in HIV-positive Patients (ETRAL QD) (ETRALQD)

HIV Infections

France
AstraZeneca
Daiichi Sankyo Co., Ltd.

Active, not recruiting

A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations (DPT01)

Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast

Italy, Spain, United States, France, Korea, Republic of, Japan, Canada, Denmark, Belgium
Poitiers University Hospital

Completed

Glivec in Pediatric Chronic Myeloid Leukemia (CML)

Chronic Myeloid Leukemia

France
Hospices Civils de Lyon

Completed

Panton Valentine Leucocidin (PVL)

Staphylococcus Aureus Pneumonias

France
Centre Hospitalier Universitaire de Besancon

Completed

Targeting Leukemic Stem Cell Expressing the IL-1RAP Protein in Chronic Myelogenous Leukemia (CML) (CAR-LMC)

Chronic Myeloid Leukemia

France
Hospices Civils de Lyon

Completed

Comparative Study of Neoadjuvant Chemotherapy With and Without Zometa for Management of Locally Advanced Breast Cancers (NEOZOL)

Locally Advanced Breast Cancer | Ductal Histologic Type | Without Her 2 Overexpression

France
Novartis Pharmaceuticals

Terminated

Phase 1b/2 Study of BKM120 Plus Trastuzumab in Patients With HER2-positive Breast Cancer

Metastatic Breast Cancer | HER2+ Breast Cancer

Belgium, France, Spain, United States, United Kingdom, Italy
Poitiers University Hospital

Active, not recruiting

Innate T Cells and TKI Discontinuation (TIBIOP-LMC)

Chronic Myeloid Leukemia

France
Centre Hospitalier Universitaire Dijon

Recruiting

Adjunction of Daptomycin for the Treatment of Pneumococcal Meningitis (AddaMAP)

Pneumococcal Meningitis

France
Centre Hospitalier Universitaire de Saint Etienne
Institut de Cancérologie de la Loire

Recruiting

Interest of PHARMaceutical Conciliation to Understand Drug Interactions, Phytotherapy, and Targeted Therapies in Chronic Myeloid Leukemia (PHARM-LMC)

Chronic Myeloid Leukemia

France
ETOP IBCSG Partners Foundation
GlaxoSmithKline; Development Limited

Recruiting

Niraparib Added to Anti-PD-L1 Antibody Maintenance in SLFN11-positive, Extensive-disease SCLC (RAISE)

SCLC,Extensive Stage | SLFN11-positive

Switzerland, France, Spain, Italy
Weill Medical College of Cornell University

Completed

A 14 Day Early Bactericidal Activity Study of Nitazoxanide for the Treatment of Tuberculosis

Tuberculosis

Haiti
Centre Hospitalier Universitaire de Nīmes

Recruiting

Is There an Association Between Innate CD8+ T Cells and the Evolution of Tyrosine Kinase Inhibitor Resistance Mutations in Phi+ Hematological Malignancies. (TIPHI)

Leukemia | Chronic Leukemia | Myelogenous Leukemia | BCR-ABL Positive Acute Myeloid Leukemia

France
Centre Hospitalier Universitaire, Amiens

Recruiting

CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections (CLAZI)

Mycobacterium Avium Complex | Lung Infection

France
Assistance Publique - Hôpitaux de Paris
Recherche Clinique Paris Descartes Necker Cochin Sainte Anne; EUCLID Clinical... and other collaborators

Completed

Innovative Anti-pneumococcal Vaccine Strategies in Patients With ANCA-associated Vasculitis Receiving Rituximab Therapy (PNEUMOVAS)

Invasive Pneumococcal Infection

France
Assistance Publique - Hôpitaux de Paris

Unknown

Long-term Clinico-radiological Evolution of Patients With Brain Lesions During Infectious Endocarditis (POST-IMAGE)

Infectious Endocarditis

France
Hospices Civils de Lyon

Completed

Nilotinib + Pegylated Interferon Alpha 2a for Untreated Chronic Phase Chronic Myelogenous Leukemia (NILOPEG)

Chronic Myelogenous Leukemia

France
University Hospital, Grenoble

Recruiting

Chronic Inflammatory Rheumatism: Management of Comorbidities in Ambulatory Medicine (SCORIC-A)

Chronic Inflammatory Disease

France
Rennes University Hospital

Completed

Effects of Silica and Asbestos Fibres on the Efferocytosis Capacities of Macrophages (MacFibOsis)

History of Exposure to Silica or Asbestosis | Positive Testing for ANA as a Marker of Systemic Autoimmune Diseases

France
University Hospital, Bordeaux

Completed

Contribution of 18F-FDG PET-CT in the Diagnosis and the Detection of Peripheral Emboli of Infectious Endocarditis on Native Valves (NATIVTEP)

Endocarditis

France
Jules Bordet Institute
Hoffmann-La Roche

Active, not recruiting

Neoadjuvant Study of Targeting ROS1 in Combination With Endocrine Therapy in Invasive Lobular Carcinoma of the Breast (ROSALINE) (ROSALINE)

HER2-negative Breast Cancer | ER+ Breast Cancer | Invasive Lobular Breast Carcinoma

France, Belgium
Centre Leon Berard

Active, not recruiting

Safety and Efficacy of Ponatinib Followed by Imatinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase (TIPI)

Philadelphia Chromosome Positive CML | BCR-ABL Positive Chronic Myelogenous Leukemia

France
Assistance Publique - Hôpitaux de Paris

Recruiting

A Phase III Randomized Trial of the Reduction of Chemotherapy in Philadelphia Chromosome-positive ALL of Young Adults (GRAAPH2014)

Philadelphia Chromosome Positive Adult Acute Lymphoblastic Leukemia

France
Novartis Pharmaceuticals

Recruiting

Asciminib Prospective Non Interventional Study as 3rd Line Therapy or More to Treat Adult Patients With CML- CP in Real World Setting in France (ASSURE-3)

Chronic Myeloid Leukemia

France
Centre Hospitalier Universitaire, Amiens

Recruiting

Study of the Prognosis of Infectious Endocarditis (EPEI) (EPEI)

Endocarditis Infective

France
Centre Hospitalier Universitaire de Nīmes

Completed

Catastrophism in Chronic Inflammatory Rheumatism (CRIC)

Chronic Inflammatory Rheumatism

France
Jazz Pharmaceuticals
BeiGene, Ltd.

Active, not recruiting

A Study of ZW25 (Zanidatamab) in Subjects With Advanced or Metastatic HER2-Amplified Biliary Tract Cancers (HERIZON-BTC-01)

HER2-amplified Biliary Tract Cancers

United States, Spain, United Kingdom, Korea, Republic of, Canada, China, Italy, Chile, France

Clinical Trials on HER2 Positive in France

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