Clinical Trials on HERG Gene Mutation
Total 2789 results
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Institut BergoniéRecruitingPTEN Gene MutationFrance
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Calithera Biosciences, IncTerminatedNon-Small Cell Lung Cancer | Non-squamous Non-small-cell Lung Cancer | Non-Squamous Non-Small Cell Neoplasm of Lung | KEAP1 Gene Mutation | NRF2 Gene Mutation | NFE2L2 Gene MutationUnited States
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ETOP IBCSG Partners FoundationAstraZenecaActive, not recruitingNSCLC Stage IV | EGFR Gene MutationSingapore, Sweden, Korea, Republic of, Spain, Switzerland, Netherlands, Italy, Poland
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Zhejiang Cancer HospitalRecruitingHER2 Gene Mutation | Bile Duct Adenocarcinoma Non-ResectableChina
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National University of MalaysiaRecruitingin Vitro Maturation | Cumulus Cell | Increased Oocyte Death | GREM1 Gene MutationMalaysia
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Assistance Publique - Hôpitaux de ParisCompletedPulmonary Alveolar Proteinosis | Mutation Ala393Thr of the MARS Gene | mutationSer567Leu of the MARS GeneFrance
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Yuhan CorporationActive, not recruitingEGFR Gene MutationKorea, Republic of
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Centre Francois BaclesseGFPCRecruitingALK Gene Rearrangement Positive | NSCLC Stage IV | NSCLC Stage IIIB | EGFR Gene Mutation | ROS1 Gene MutationFrance
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Dana-Farber Cancer InstituteGenentech, Inc.RecruitingSalivary Gland Cancer | HER2 Gene MutationUnited States
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University of ChicagoRecruitingMyeloproliferative Neoplasm | Blood Cancer | IDH2 Gene Mutation | IDH1 Mutation | IDH MutationUnited States
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H. Lee Moffitt Cancer Center and Research InstituteTerminatedBreast Cancer | Breast Cancer, Male | HER2-positive Breast Cancer | HER-2 Gene Amplification | Breast Cancer Female | HER2 Positive Breast Carcinoma | HER-2 Protein OverexpressionUnited States
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Enliven TherapeuticsRecruitingHER2-positive Metastatic Breast Cancer | HER2 Gene Mutation | HER2 Mutant Non-small Cell Lung Cancer | HER2 AmplificationSpain, United States, Korea, Republic of, Taiwan, Italy, Australia, France
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Ege UniversityCompletedHigh Myopia | Gene Mutations
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The First Hospital of Jilin UniversityRecruiting
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Shanghai Chest HospitalJiangsu Hansoh Pharmaceutical Co., Ltd.Not yet recruitingLung Cancer | EGFR Gene Mutation
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Bellicum PharmaceuticalsSuspendedHER2-positive Breast Cancer | HER2-positive Gastric Cancer | Solid Tumor, Adult | HER-2 Gene Amplification | HER-2 Protein OverexpressionUnited States
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Thomas Jefferson UniversityCompletedStage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Health Care Provider | Activating ALK Gene Mutation Negative | Activating EGFR Gene Mutation Negative | Activating ROS1 Gene Mutation NegativeUnited States
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Groupe Francophone des MyelodysplasiesAprea TherapeuticsUnknownChronic Myelomonocytic Leukemia | Myeloproliferative Neoplasm | Acute Myeloid Leukemia With Gene Mutations | Myelodysplastic Syndrome With Gene MutationFrance
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Masaryk UniversityBrno University Hospital; Roche s.r.o.RecruitingCentral Nervous System Neoplasms | Pediatric Cancer | Tumor, Brain | GEN1 Gene MutationCzechia
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Memorial Sloan Kettering Cancer CenterMerck Sharp & Dohme LLC; Genentech, Inc.RecruitingEsophageal Cancer | Gastric Adenocarcinoma | HER2 Gene MutationUnited States
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SensorionRecruitingSensorineural Hearing Loss, Bilateral | Congenital Deafness | AUNB1 | DFNB1A | DFNB9 | OTOF Gene Mutation | GJB2 Gene MutationFrance
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Calithera Biosciences, IncTerminatedNon-Small Cell Lung Cancer | Non-squamous Non-small-cell Lung Cancer | Non-Squamous Non-Small Cell Neoplasm of Lung | KEAP1 Gene Mutation | NFE2L2 Gene Mutation | NRF2 MutationUnited States
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Nantes University HospitalTerminated
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NRG OncologyNational Cancer Institute (NCI)Active, not recruitingGlioma | Oligoastrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Diffuse Astrocytoma | WHO Grade III Glioma | IDH2 Gene Mutation | IDH1 Gene Mutation | 1p/19q Co-deletionUnited States
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Imperial College London Diabetes CentreUnknownMendelian Disorders | Genetic Disorder | Novel Mutation | Hereditary Disorder | De Novo Mutation | Inherited Disease | Single-Gene DefectsUnited Arab Emirates
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Korean Association for the Study of Targeted TherapyChonnam National University Hospital; Kyungpook National University Hospital; Konkuk University Medical Center and other collaboratorsCompletedHER2 Gene Mutation | Adenocarcinoma Lung Stage IVKorea, Republic of
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)WithdrawnPancreatic Ductal Adenocarcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Homologous Recombination Deficiency | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | ATM Gene Mutation | Deleterious BRCA1 Gene... and other conditions
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University of VirginiaNot yet recruitingGenetic Predisposition | Gene Mutation-Related Cancer
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Institut CurieRecruitingGenetic Predisposition | Gene Mutation-Related CancerFrance, Guadeloupe, Martinique, Réunion
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University Health Network, TorontoAbbVie; CelgeneTerminatedAcute Myeloid Leukemia | Relapsed Cancer | Refractory Cancer | IDH2 Gene MutationCanada
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National Cancer Institute (NCI)CompletedBRCA1 Gene Mutation | BRCA2 Gene Mutation | Recurrent Breast Carcinoma | Estrogen Receptor Negative | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Negative | Progesterone Receptor Positive | Triple-Negative Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage IIIB Breast... and other conditionsUnited States
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Tel-Aviv Sourasky Medical CenterUnited States Department of DefenseRecruitingEvaluation of the Frequency and Severity of Sleep Abnormalities in Patients With Parkinson's DiseaseParkinson Disease | GBA Gene Mutation | Leucine-rich Repeat Kinase 2 (LRRK2) Gene MutationIsrael
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Centre Hospitalier Universitaire de Saint EtienneCompleted
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Recursion Pharmaceuticals Inc.RecruitingSolid Tumor | APC Gene Mutation | AXIN1 Gene MutationUnited States
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HutchmedRecruitingIsocitrate Dehydrogenase Gene MutationSpain, United States
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Women's College HospitalCanadian Institutes of Health Research (CIHR); London Health Sciences Centre; H. Lee Moffitt Cancer Center and Research Institute and other collaboratorsUnknownBreast Cancer | Ovarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene MutationCanada
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National Cancer Institute (NCI)Glaxosmithkline Biologicals S.A.TerminatedRenal Failure | Solid Neoplasm | BRAF Gene Mutation | Hepatic ComplicationUnited States, Canada
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Simons SearchlightBoston Children's Hospital; Geisinger Clinic; Simons FoundationRecruitingSMARCA4 Gene Mutation | DDX3X | 16P11.2 Deletion Syndrome | 16p11.2 Duplications | 1Q21.1 Deletion | 1Q21.1 Microduplication Syndrome (Disorder) | ACTL6B | ADNP | AHDC1 | ANK2 | ANKRD11 | ARID1B | ASH1L | BCL11A | CHAMP1 | CHD2 | CHD8 | CSNK2A1 | CTBP1 | CTNNB1 Gene Mutation | CUL3 | DNMT3A | DSCAM | DYRK1A | FOXP1 | GRIN2A | GRIN2B | HIVEP2-Related Intellectual... and other conditionsUnited States
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Institut Claudius RegaudRecruitingDDX41 Gene MutationFrance
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Stanford UniversityNovartis PharmaceuticalsCompletedAmeloblastoma | BRAF Gene MutationUnited States
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Taiho Oncology, Inc.TerminatedAdvanced or Metastatic Solid Tumors Irrespective of Gene Alterations | Advanced or Metastatic Solid Tumors With Germline PTEN Inactivating MutationsUnited States, United Kingdom, Austria, France
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AZ-VUBAstraZeneca; Kom Op Tegen KankerRecruitingAdvanced Cancers Harbouring Mutations in HRGBelgium
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xCuresTerminatedTransitional Cell Carcinoma | Bladder Cancer | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | FGFR2 Gene Mutation | FGFR3 Gene Mutation | FGFR2 Amplification | Bladder Urothelial Carcinoma | Locally Advanced Urothelial Carcinoma | Refractory Bladder Carcinoma | Refractory Bladder Urothelial Carcinoma and other conditionsUnited States
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University of WashingtonActive, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Castration-Resistant Prostate Carcinoma | Homologous Recombination Deficiency | PSA Progression | Stage IV Prostate Adenocarcinoma AJCC v7 | Castration Levels of Testosterone | ATM Gene Mutation | Prostate Carcinoma Metastatic in the Bone | PSA Level Greater...United States
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Shirish M GadgeelAstraZeneca; Henry Ford Health SystemWithdrawnLung Cancer | Non-small Cell Lung Cancer | PD-L1 Gene Mutation | KRAS Activating MutationUnited States
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Ascletis Pharmaceuticals Co., Ltd.RecruitingHIV Infections | HIV-1-infection | PD-L1 Gene MutationChina
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Ambrx, Inc.WithdrawnHER2 Mutation-Related Tumors | HER2 Amplified Solid TumorsUnited States
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Yongchang ZhangRecruitingHER2 Insertion Mutation Positive Advanced NSCLCChina
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University of Southern CaliforniaNational Cancer Institute (NCI)Active, not recruitingStage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer | ALK Gene Mutation | EGFR Gene Mutation | Metastatic Head and Neck... and other conditionsUnited States
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University of Wisconsin, MadisonRecruitingERα+ Breast Cancer | ESR1 Gene MutationUnited States