Clinical Trials on HIF-2α Mutated Cancers
Total 143 results
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NiKang Therapeutics, Inc.RecruitingKidney Cancer | Kidney Neoplasms | Renal Cell Carcinoma | Clear Cell Renal Cell Carcinoma | Hypoxia | Metastatic Renal Cell Carcinoma | Recurrent Renal Cell Carcinoma | Renal Cancer | Advanced Renal Cell Carcinoma | Renal Neoplasms | ccRCC | Refractory Renal Cell Carcinoma | Hypoxia Inducible Factor (HIF) | HIF2α... and other conditionsUnited States
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Peking University People's HospitalJiangsu Hengrui Pharmaceutical Co., Ltd.Enrolling by invitationGermline BRCA-mutated HER2-negative Breast CancerChina
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Revolution Medicines, Inc.RecruitingNon-Small Cell Lung Cancer, NSCLC | KRAS, NRAS, HRAS-mutated NSCLC | KRAS G12C-mutated Solid Tumors, Lung Cancer | Lung Cancer Stage IV, Advanced Solid Tumor, CancerUnited States
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AbbVieCompletedOncology | High Grade Serous Ovarian Cancer | BRCA Mutated | BRCA Mutated Breast Cancer
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Pamela MunsterQuantumLeap Healthcare CollaborativeTerminatedTriple Negative Metastatic Breast Cancer | BRCA-mutated Solid TumorUnited States
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National Cancer Institute, NaplesRecruitingRas-mutated Metastatic Colorectal CancerItaly
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Merck Sharp & Dohme LLCRecruitingVon Hippel-Lindau Disease | Pancreatic Neuroendocrine Tumor | Pheochromocytoma/Paraganglioma | Advanced Gastrointestinal Stromal Tumor | HIF-2α Mutated CancersCanada, United States, Denmark, France, Germany, Hungary, Italy, Russian Federation, Spain, Sweden, Turkey, Israel, United Kingdom, Netherlands, Australia, China, Singapore, Japan
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Tocagen Inc.TerminatedMelanoma | Sarcoma | Lymphoma | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | IDH1 Mutated Solid Tumors | IDH1 Mutated or MGMT Methylated Recurrent HGG (Not Recruiting)United States
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The First Affiliated Hospital of Zhengzhou UniversityBeiGene; Jiangsu Hengrui Pharmaceutical Co., Ltd.; RemeGen Co., Ltd.Not yet recruitingHER2-positive or Mutated Advanced Colorectal Cancer
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Institut du Cancer de Montpellier - Val d'AurelleCompletedMetastatic Colorectal Cancer Patients With KRAS Mutated TumorsFrance
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Shanghai Pharmaceuticals Holding Co., LtdNot yet recruitingBiliary Tract or Colorectal Cancer With Her2-positive/MutatedChina
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Sierra Oncology, Inc.TerminatedRelapsed Metastatic KRAS-Mutated Non-Small Cell Lung CancerUnited States
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Novartis PharmaceuticalsCompletedStomach Neoplasms Esophageal Neoplasms Metastatic Gastric Cancer Mutated PI3KCA Protein Overexpressed HER2 ProteinTaiwan, Switzerland, Korea, Republic of, Germany, United States, Japan
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National Cancer Centre, SingaporeRecruitingAdvanced EGFR Exon 20 Insertion Mutated Non-Small Cell Lung CancerKorea, Republic of, Taiwan, Singapore
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Cancer Institute and Hospital, Chinese Academy...RecruitingBevacizumab | Capecitabine | Metastatic Colorectal Cancer (mCRC) | Oxaliplatin | Tislelizumab | First-Line | MSS/pMMR | RAS-mutatedChina
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West China HospitalRecruitingBRAF V600E-mutated /MSS Metastatic Colorectal Cancer | Vemurafenib (BRAFi) Plus Cetuximab (EGFRi) Combined With PD-1 Monoclonal AntibodyChina
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AstraZenecaCompletedEGFR Mutated Non-small Cell Lung Cancer PatientsSpain
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Daiichi SankyoAvailableEpidermal Growth Factor Receptor (EGFR)-Mutated Non Small Cell Lung CancerUnited States
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European Organisation for Research and Treatment...SanofiWithdrawnColorectal Cancer Metastatic | Liver Metastases | KRAS Mutated Colorectal Cancer
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Sierra Oncology, Inc.TerminatedEGFR Mutated EGFR TKI Naive Metastatic NSCLCUnited States
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Sichuan Provincial People's HospitalTerminatedStage IV EGFR Mutated Non-Small Cell Lung CancerChina
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AstraZenecaParexel; Covance; Iqvia Pty Ltd; Theradex; Myriad Genetics, Inc.CompletedNon-Germline BRCA Mutated Ovarian CancerItaly, Spain, Sweden, Canada, Czechia, Poland, United Kingdom, Israel, Austria, Belgium, Switzerland, Netherlands, Bulgaria, Finland, Norway, Denmark, Slovenia, Portugal
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AstraZenecaCompletedBRCA or HRR+ Mutated Ovarian Cancer PatientsItaly, Spain, Canada, Czechia, Poland, United Kingdom, Hungary, Bulgaria
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Novartis PharmaceuticalsActive, not recruitingLocally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutationSpain, Italy, Austria, Netherlands, United Kingdom, Thailand, France, Belgium, China, Germany, Greece, Argentina, Turkey, Malaysia, Portugal, Brazil, United States, Hungary, India
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Guangdong Association of Clinical TrialsNot yet recruitingDacomitinib for EGFR Mutated Non-Small Cell Lung Cancer (NSCLC) With Brain Metastases
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AstraZenecaMerck Sharp & Dohme LLC; European Network of Gynaecological Oncological Trial... and other collaboratorsActive, not recruitingRelapsed Ovarian Cancer | Following Complete or Partial Response to Platinum Based Chemotherapy | Platinum Sensitive | BRCA MutatedKorea, Republic of, France, China, Italy, United States, Israel, United Kingdom, Canada, Japan, Germany, Brazil, Netherlands, Belgium, Poland, Australia, Russian Federation, Spain
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National Cancer Institute (NCI)RecruitingEGFR-Mutated Non-Small-Cell Lung Carcinoma | Small Cell/NeuroendocrineUnited States
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Aprea TherapeuticsCompletedPlatinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53United States, France, Spain, Netherlands, United Kingdom, Belgium, Germany, Sweden
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Rajavithi HospitalUnknownTo Study Immunostatus of HIV-cancer Patients Who Recived RT Befor RT and Last Week of RT | To Study HIV Viral Load of HIV-cancer Patients Who Recived RT Befor RT and Last Week of RTThailand
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Haihe Biopharma Co., Ltd.TerminatedMelanoma | Erdheim-Chester Disease | Non-Small-Cell Lung Cancer | Advanced Tumors | Other RAS/RAF/MEK/ERK Mutated TumorsUnited States, China
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Tango Therapeutics, Inc.TerminatedBreast Cancer | Ovarian Cancer | Prostate Cancer | Pancreas Cancer | BRCA1 Mutation | BRCA-Mutated Ovarian Carcinoma | BRCA-Associated Breast Carcinoma | HRD Positive Advanced Ovarian CancerUnited States
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National Cancer Institute (NCI)Completed
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Assistance Publique - Hôpitaux de ParisMinistry of Health, FranceTerminatedBrain Metastasis | EGFR-mutated Lung AdenocarcinomaFrance
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Felix GutierrezHospital Clinic of Barcelona; Hospital General Universitario Elche; Germans Trias... and other collaboratorsRecruiting
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ANRS, Emerging Infectious DiseasesBicetre Hospital; Pitié-Salpêtrière HospitalUnknownHIV Infected Patients With Cancer Treated by ICPiFrance
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Imperial College LondonImperial College Healthcare NHS TrustCompleted
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University of MiamiAmerican Cancer Society, Inc.Recruiting
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Sumitomo Pharma America, Inc.CompletedAdvanced Solid Tumors | Recurrent Ovarian Carcinoma | Colorectal Carcinoma | EGFR Positive Non-small Cell Lung Cancer | BRAF-Mutated MelanomaUnited States
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NYU Langone HealthRecruitingMLH1 Gene Mutation | RAD51C Gene Mutation | BRIP1 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | BRCA-Mutated Ovarian Carcinoma | MSH2 A636P | EPCAMUnited States
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Intergroupe Francophone de Cancerologie ThoraciqueCompletedNon-small Cell Lung Cancer | Hiv-positiveFrance
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M.D. Anderson Cancer CenterUnknownCervical Cancer | Endometrial Cancer | Vaginal CancerUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedCancer Prevention | CervixUnited States
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Rigshospitalet, DenmarkRecruitingMetastatic Cancer to the HipDenmark
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Goethe UniversityHIVCENTERUnknownCancer | Immunosuppression | HIV-1 InfectionGermany
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Duke UniversityNational Cancer Institute (NCI)TerminatedNewly Diagnosed Cancer Patients Who Are HIV Positive and Their Treating OncologistUnited States
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Blueprint Medicines CorporationActive, not recruitingNeoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Metastatic Lung Cancer | Antineoplastic Agents | Brain Metastases | Lung Neoplasm Malignant | EGFR... and other conditionsUnited States, Canada, Korea, Republic of, Japan, Taiwan
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Sidney Kimmel Comprehensive Cancer Center at Johns...CompletedHIV Infections | Lung Cancer | HIV Seropositivity | Lung Cancer in the HIV Patient
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NeurexCompletedHIV Infections | Pain | CancerUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Primary Peritoneal High Grade Serous Adenocarcinoma | Stage III Fallopian Tube Cancer AJCC v8 | Stage III Ovarian Cancer AJCC v8 | Stage III Primary Peritoneal Cancer AJCC v8 | Stage IIIA Fallopian Tube Cancer AJCC v8 | Stage IIIA Ovarian Cancer AJCC v8 | Stage... and other conditionsUnited States