Clinical Trials on HIV-1 Infections

Total 66260 results

Chelsea and Westminster NHS Foundation Trust

Recruiting

Efficacy of Doravirine + Dolutegravir Dual Therapy in the Context of Antiretroviral Therapy Switch (DORDOL)

HIV-1-infection

United Kingdom
University Hospital, Ghent
ViiV Healthcare

Recruiting

2DR Versus 3DR in a Prospective Randomized Controlled Switch Trial (2DR)

HIV-1-infection

Belgium
MSD Pharmaceuticals LLC

Completed

ART First-line Treatment Durability in Russia

HIV-1-infection

Russian Federation
University of Washington
National Institute on Drug Abuse (NIDA); Makerere University

Active, not recruiting

Uganda PrEP and Harm Reduction Evaluation

HIV-1-infection

Uganda
University of Florida
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

ANCHORS Study: UH2 Project (ANCHORS)

HIV-1-infection

United States
Quest Clinical Research
Gilead Sciences

Completed

Bictegravir/Emtricitabine/Tenofovir Alafenide Plus Doravirine

HIV-1-infection

United States
Centre Hospitalier Universitaire Dijon

Completed

Optimization of HIV-1 DNA Genotyping by High Throughput Sequencing to Document Antiretroviral Resistant Mutations (Mutapro)

HIV-1-infection

France
Gilead Sciences
Merck Sharp & Dohme LLC

Active, not recruiting

Study Evaluating the Safety and Efficacy of Islatravir in Combination With Lenacapavir in Virologically Suppressed People With HIV

HIV-1 Infection

United States
National Institute of Allergy and Infectious Diseases...
National Institutes of Health (NIH); Department of Health and Human Services

Active, not recruiting

Trial to Evaluate the Safety and Immunogenicity of Priming Regimens of 426c.Mod.Core-C4b Adjuvanted With 3M-052-AF + Alum in Healthy, HIV-1 Uninfected Adult Participants

HIV-1-infection

United States
Radboud University Medical Center
Erasmus Medical Center; Elisabeth-TweeSteden Ziekenhuis; Onze Lieve Vrouwe Gasthuis

Completed

2000HIV Trained Innate Immunity in HIV Elite Controllers (2000HIVTrained)

HIV-1-infection

Netherlands
TaiMed Biologics Inc.
Westat

Completed

Study of the Safety of Trogarzo™ Administered as an Undiluted "IV Push" or an Intramuscular Injection

HIV-1-infection

United States
Judit Pich Martínez
Gilead Sciences

Completed

A Test and Treat Strategy in New HIV Diagnosis. (Test&Treat)

HIV-1-infection

Spain
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding a Native-like HIV Env Trimer and Interleukin-12 (INO-6160), Alone or in a Prime-boost Regimen With 3M-052-AF + Alum Adjuvanted VRC HIV Env Trimer 4571 in Adult Participants Without HIV

HIV-1-infection

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); United States...

Completed

Assess Therapeutic Efficacy and Emergence of HIV Drug Resistance Following Initiation of TLD

HIV-1-infection

Kenya, South Africa, Haiti, Malawi, Uganda, Zimbabwe
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Withdrawn

Pharmacokinetic Interactions of ENG Subdermal Implants With Long-Acting Cabotegravir (CAB-LA) and LA Rilpivirine (RPV-LA) (CARLA)

HIV-1-infection
Professor Francois Venter

Completed

DORA: A Doravirine-based First-line Antiretroviral Therapy for Women of Reproductive Potential Living With HIV (DORA)

HIV-1-infection

South Africa
Steven Deeks
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Therapeutic Vaccination in Treated HIV Disease

HIV-1-infection

United States
Viriom

Completed

Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact of Food Intake and Drug-Drug Interactions With Other Antiviral Drugs

Hepatic Impairment | HIV-1-infection

Russian Federation
Fundacion Ibis

Unknown

Telemedicine in HIV Care in Buenos Aires

Telemedicine | HIV-1-infection
Taiwan AIDS Nurse Society
GlaxoSmithKline

Unknown

Quality of Life of Taiwan People Living With HIV

HIV-1-infection

Taiwan
Henry M. Jackson Foundation for the Advancement...
US Military HIV Research Program; Janssen Vaccines & Prevention B.V.

Withdrawn

Safety and Efficacy of Neutralizing Antibodies and Vaccination for Induction of HIV Remission (RV582)

HIV-1-infection

Thailand
The Wistar Institute
University of Pennsylvania; Merck Sharp & Dohme LLC

Completed

Pilot Peg-Interferon-a2b in Decreasing Viral DNA in HIV

HIV-1 Infection

United States
Gilead Sciences

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of E/C/F/TAF Fixed Dose Combination (FDC) in HIV-1 Infected Adults on Chronic Hemodialysis

HIV-1 Infection

United States, France, Austria, Germany
Ottawa Hospital Research Institute
Pfizer

Completed

A Drug Interaction Study Investigating the Effect of Rifabutin on the Pharmacokinetics of Maraviroc (RIFAMARA)

HIV Infection | HIV-1 Infection | Mycobacterium Avium Complex (MAC)

Canada
University of Oxford

Completed

Safety and Immunogenicity Study of Three Candidate HIV-1 Vaccines, Administered in Combination to Healthy HIV-1 Uninfected Adults (HIV-CORE 002)

HIV-1 Infections

United Kingdom
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Recruiting

Implementation of Out-of-HOspital Administration of the Long-Acting Cabotegravir+Rilpivirine (HOLA)

HIV-1 Infection

Spain
Advancing Clinical Therapeutics Globally for HIV...
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Observational PIC Destination Cohort

HIV-1-infection

United States
Professor Francois Venter
Merck Sharp & Dohme LLC; Africa Health Research Institute

Recruiting

A Randomised, Phase 3 Non-inferiority Study of DOR/3TC/TDF Compared to DTG/TAF/FTC in Participants Infected With HIV-1 Starting First-line Antiretroviral Therapy (Opti-DOR)

HIV-1-infection

South Africa
Merck Sharp & Dohme LLC

Recruiting

DOR/ISL in HIV-1 Antiretroviral Treatment-naïve Participants (MK-8591A-053)

HIV-1 Infection

United States, Israel, Puerto Rico, Japan, South Africa, Chile, Thailand, United Kingdom
University of Aarhus
Aarhus University Hospital; The Alfred; The Peter Doherty Institute for Infection... and other collaborators

Recruiting

Administration of Venetoclax to Promote Apoptosis of HIV-infected Cells and Reduce the Size of the HIV Reservoir Among People Living With HIV on ART (AMBER)

HIV-1-infection

Denmark
MRC/UVRI and LSHTM Uganda Research Unit
Janssen Pharmaceuticals

Recruiting

Improving HIV-1 Control in Africa With Long Acting Antiretrovirals (IMPALA)

HIV-1-infection

South Africa, Kenya, Uganda
Gilead Sciences

Recruiting

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen (ARTISTRY-1)

HIV-1-infection

Japan, Germany, France, United States, Spain, Korea, Republic of, South Africa, Australia, Argentina, Canada, Dominican Republic, Italy, Puerto Rico, Taiwan, United Kingdom
Orlando Immunology Center
ViiV Healthcare

Recruiting

Changes in Immunologic Parameters Following the Addition of Fostemsavir in Virologically Suppressed Immunologic Non-responders Living With HIV-the RECOVER Study

HIV-1-infection

United States
Centre Hospitalier Universitaire de Nīmes
Institut de Génétique Moléculaire de Montpellier

Recruiting

Bioclinical Evaluation of 2 Biomarkers of Aviremic HIV-1 in CD4+ T Cells of Adults Undergoing Treatment (RESERVIH32)

HIV-1-infection

France
University of California, San Francisco
Merck Sharp & Dohme LLC

Recruiting

Pharmacokinetics Distribution of Raltegravir by PET/MR

HIV-1-infection

United States
IRCCS San Raffaele
Bristol-Myers Squibb

Completed

Efficacy of Atazanavir/Ritonavir Monotherapy as Maintenance in Patients With Viral Suppression

HIV-1 Infection

Italy
Sangamo Therapeutics

Terminated

Long-term Follow-up of HIV Subjects Exposed to SB-728-T or SB-728mR-T

HIV-1-infection

United States
National Institute of Allergy and Infectious Diseases...
Sanofi; ModeX Therapeutics

Terminated

Pharmacokinetics and Safety of SAR441236

HIV-1-infection

United States
University of Texas at Austin
Merck Sharp & Dohme LLC; Texas Health Institute; Transgender Education Network...

Completed

Longer-Acting PrEP in Transgender and Gender Diverse Texans

HIV-1-infection

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Dose Ranging, Switch Study of Islatravir (ISL) and Ulonivirine (MK-8507) Once-Weekly in Virologically-Suppressed Adults With Human Immunodeficiency Virus Type 1 (HIV-1) [MK-8591-013]

HIV-1 Infection

United States, France, Switzerland
Merck Sharp & Dohme LLC

Active, not recruiting

A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Antiretroviral Therapy (ART) (MK-8591A-051)

HIV-1 Infection

United States, Australia, Canada, Colombia, Japan, South Africa, Switzerland, United Kingdom
Massachusetts General Hospital
Harvard Medical School (HMS and HSDM); National Institute of Allergy and Infectious... and other collaborators

Completed

Population Effectiveness of Dolutegravir Implementation in Sub-Saharan Africa (DISCO)

HIV-1-infection

Uganda, South Africa
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Lenacapavir in Combination With Other Antiretroviral Agents in People Living With HIV (CALIBRATE)

HIV-1-infection

United States, Puerto Rico, Dominican Republic
Fundacion Clinic per a la Recerca Biomédica

Active, not recruiting

Switch Strategy From Etravirine (ETR) to Doravirine (DOR) in Virologically-Suppressed HIV-1 Infected Adults With ETR-Resistance

HIV-1-infection

Spain
Epividian
Theratechnologies; FIECON

Completed

External Comparison of Ibalizumab in Trials vs. Other Regimens in OPERA

HIV-1-infection

United States
ANRS, Emerging Infectious Diseases
Mylan Laboratories

Active, not recruiting

ANRS 12372 MODERATO Study (MODERATO)

HIV-1-infection

Côte D'Ivoire, Burkina Faso, Cameroon
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); National Institute...

Completed

PREPARE (A5361s) Substudy of REPRIEVE (A5332) (PREPARE)

HIV-1 Infection

United States, Puerto Rico
Radboud University Medical Center
University Medical Center Groningen; Erasmus Medical Center; Leiden University...

Withdrawn

Pharmacokinetics of Single-dose Dolutegravir in HIV-seronegative Subjects With Severe Hepatic Impairment Compared to Matched Controls. (POLO)

Hepatic Impairment | HIV-1-infection
University Hospital, Bordeaux

Completed

Cytomegalovirus Infection in Patients With HIV-1 Infection (ACTHIV)

Cytomegalovirus Infections | HIV-1-infection
Gilead Sciences

Completed

Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment Naive, HIV-1 and Hepatitis B Co-Infected Adults (Alliance)

HIV-1/HBV Co-Infection

Spain, Taiwan, Korea, Republic of, Thailand, Hong Kong, Japan, France, Turkey, Puerto Rico, Malaysia, United States, China, Dominican Republic, Greece

Clinical Trials on HIV-1 Infections

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