Clinical Trials on HIV-1 Infection

Total 70911 results

Janssen-Cilag Pty Ltd

Completed

An Efficacy and Safety Study of Autologous Cluster of Differentiation 34 (CD34+) Hematopoietic Progenitor Cells Transduced With Placebo or an Anti- Human Immunodeficiency Virus Type 1 (HIV-1) Ribozyme (OZ1) in Participants With HIV-1 Infection

HIV-1

Australia
Gilead Sciences

Completed

Safety and Efficacy of Cobicistat-boosted Atazanavir Compared to Ritonavir-boosted Atazanavir in Combination With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults

HIV-1 Infection

United States
ANRS, Emerging Infectious Diseases

Completed

4 Consecutive Days on Treatment Followed by 3 Days Off Treatment, in HIV Patients (ANRS162-4D)

HIV-1 Infection

France
Fundacion para la Investigacion Biomedica del Hospital...

Terminated

Effect of Cytoreductive Chemotherapy and a CCR5 Coreceptor Antagonist on HIV-1 Eradication (CHEMOMAR)

HIV-1 Infection

Spain
University Hospital, Strasbourg, France

Unknown

Impact of Starting a Dolutegravir-based Regimen on HIV-1 Proviral DNA Reservoir Of Treatment Naïve and Experienced Patients (DRONE)

HIV-1 Infection

France
InnaVirVax

Completed

Phase I/IIa Dose-escalation Clinical Study of VAC-3S

HIV-1 Infection

France
Centre Hospitalier Universitaire Saint Pierre
Gilead Sciences; University of Liege; Abbott; Pierre and Marie Curie University; University... and other collaborators

Completed

Nevirapine vs Ritonavir-boosted Lopinavir in ART Naive HIV-infected Adults in a Resource Limited Setting

HIV-1 Infection

Congo
Tobira Therapeutics, Inc.

Completed

A Proof of Concept Study to Evaluate the Antiviral Activity, Safety, and Pharmacokinetics of the CCR5 Antagonist TBR 652 in HIV 1-Infected, Antiretroviral Treatment-Experienced, CCR5 Antagonist-Naïve Patients

HIV-1 Infection
City of Hope Medical Center

Terminated

Gene Transfer for HIV Using Autologous T Cells (Gene Transfer)

HIV-1 Infection

United States
Brigham and Women's Hospital
Merck Sharp & Dohme LLC

Terminated

HIV-1 Viral Dynamics in Subjects Initiating Raltegravir Therapy

HIV-1 Infection

United States
Myrexis Inc.

Completed

A Phase 2 Study to Assess the Pharmacokinetics of Bevirimat 100 mg Tablets Given to HIV-1 Positive Patient for 15 Days

HIV-1 Infection

United States
MRC/UVRI and LSHTM Uganda Research Unit
Karolinska Institutet; University of California, San Francisco; European and... and other collaborators

Recruiting

Improving HIV Prevention Among Adolescent Girls and Young Women (AGYW) in Uganda (PeerPREP)

HIV-1-infection

Uganda
Tulika Singh, MD
Gilead Sciences

Recruiting

Study to Assess Switching to B/F/TAF in Treatment Experienced People With HIV Who Are at Least 65 Years of Age

HIV-1-infection

United States
Kenya Medical Research Institute
European and Developing Countries Clinical Trials Partnership (EDCTP)

Recruiting

Latent HIV-1, Viral Suppress and Hope for HIV Cure

HIV-1-infection

Kenya
ANRS, Emerging Infectious Diseases
Institut Pasteur; Hospital Laquinitinie de Douala; Franceville International...

Recruiting

ANRS 12406 EvvA Study (EvvA)

HIV-1-infection

Cameroon
UBP Greater China (Shanghai) Co., Ltd

Not yet recruiting

The HIV Functional Cure Potential of UB-421 in ART Stabilized HIV-1 Patients (HIV-1)

HIV-1-infection
United BioPharma

Withdrawn

To Investigate the Efficacy and Safety of UB-421 Monotherapy in HIV-1 Infected Adults

HIV-1 Infection

China
Merck Sharp & Dohme LLC

Completed

Evaluation of Safety, Tolerability, Pharmacokinetics, and Antiretroviral Activity of Ulonivirine (MK-8507) in Human Immunodeficiency Virus (HIV-1)-Infected Participants (MK-8507-003)

HIV-1 Infection
University Hospital, Toulouse
Institut National de la Santé Et de la Recherche Médicale, France; ANRS, Emerging...

Completed

VIH-1 Colo-rectal Transmission by Infected Semen Cells and Effects of Seminal Plasma ex Vivo (CellspermVIH) (CellspermVIH)

HIV-1-infection

France
University of Liege

Completed

Effect of Dolutegravir Intensification on HIV-1 Reservoirs (EDIT)

HIV-1-infection

Belgium
University of Oxford
Imperial College London; KEMRI-Wellcome Trust Collaborative Research Program; University of Nairobi and other collaborators

Active, not recruiting

A Study to Test Three Experimental HIV Vaccines in Healthy Adults. (HIV-CORE 006)

HIV-1-infection

Kenya, Uganda, Zambia
CytoDyn, Inc.

Active, not recruiting

An Extension Protocol for Virologically Suppressed Subjects Who Successfully Completed PRO140_CD03 Study

HIV-1-infection

United States
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Alafenamide in Human Immunodeficiency Virus (HIV-1) Infected, Antiretroviral Treatment-Naive Adults

HIV-1 Infection

Spain, United States, Italy, Germany, United Kingdom, France, Australia, Puerto Rico, Canada, Belgium, Dominican Republic
ANRS, Emerging Infectious Diseases

Completed

Gut-Associated Lymphocyte Trafficking (GALT)

HIV-1 Infection

France
Viriom

Completed

Open Labelled, Randomized Study to Evaluate the Efficacy, Safety and Dose Selection of VM-1500A-LAI Drug in HIV-infected Patients Transferred From Previous Stable Therapy (NNRTI + 2NRTI), Including ELPIDA®

HIV-1-infection

Russian Federation
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Doravirine, Tenofovir, Lamivudine (MK-1439A) in Participants Infected With Treatment-Naïve Human Immunodeficiency Virus (HIV) -1 With Transmitted Resistance (MK-1439A-030) (DRIVE BEYOND)

HIV-1 Infection
AIDS Clinical Trials Group
National Cancer Institute (NCI); National Institute of Allergy and Infectious... and other collaborators

Completed

Three Chemo Regimens as an Adjunct to ART for Treatment of Advanced AIDS-KS

HIV-1 Infection

South Africa, Brazil, Zimbabwe, Kenya, Malawi, Uganda
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)

HIV-1 Infection

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study) (TRAFIC)

HIV-1 Infection

United States, Puerto Rico
University of Melbourne
Johns Hopkins University; Oregon Health and Science University; University of... and other collaborators

Completed

HIV Persistence in Lymph Node and Peripheral Blood (HIV-PRADA)

HIV-1-infection

Australia
Imperial College London
Bill and Melinda Gates Foundation

Completed

Optimising DNA Vaccinations in Healthy Volunteers (DNAVAC001)

HIV-1-infection
Gilead Sciences

Completed

Study to Evaluate Safety, Pharmacokinetics, and Antiviral Activity of Bictegravir (GS-9883) in Human Immunodeficiency Virus (HIV)-1 Infected Participants

HIV-1 Infection

United States
Peking Union Medical College Hospital
National Key Technologies R&D Program for the 13th Five-year Plan; National... and other collaborators

Completed

Efavirenz 400mg in Treatment-naïve Chinese HIV-infected Patients

HIV-1-infection

China
Rockefeller University

Completed

3BNC117 Monoclonal Antibody in HIV-infected Subjects During Treatment Interruption

HIV-1 Infection

United States
Gilead Sciences

Completed

Study to Evaluate Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Fixed Dose Combination (FDC) in Virologically-Suppressed HIV-1 Infected Adults Harboring the Archived Isolated NRTI Resistance Mutation M184V/M184I

HIV-1 Infection

Spain, France, United States, Germany, Italy
Instituto de Investigación Hospital Universitario...

Unknown

Antiretroviral Treatment Guided by Proviral Genotype: Pilot Trial of Proof of Concept.

HIV-1-infection

Spain
The University of Texas Health Science Center,...

Completed

Safety of FMT Using Oral Encapsulated PRIM-DJ2727 in HIV

HIV-1-infection

United States
Gilead Sciences

Completed

Safety and Biological Activity of Vesatolimod in HIV-1 Infected, Virologically Suppressed Adults

HIV-1 Infection

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); Exegi Pharma...

Completed

Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome & Immune Activation Markers

HIV-1 Infection

United States, Puerto Rico
Gilead Sciences

Completed

Switch Study to Evaluate the Safety and Efficacy of Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) Fixed Dose Combination (FDC) in HIV-1 Positive Adults Who Are Virologically Suppressed on Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate (FTC/RPV/TDF)

HIV-1 Infection

United States, Spain, United Kingdom, Netherlands, Germany, Canada, Sweden, Switzerland, Italy, Belgium, Puerto Rico, France
Merck Sharp & Dohme LLC

Completed

Single-Dose Study of MK-4250 Monotherapy in Anti-Retroviral Therapy-Naive, Human Immunodeficiency Virus (HIV)-1 Infected Participants (MK-4250-002)

HIV-1 Infection

Germany
Gilead Sciences

Completed

Switch Study to Evaluate F/TAF in HIV-1 Infected Adults Who Are Virologically Suppressed on Regimens Containing ABC/3TC

HIV-1 Infection

Spain, United Kingdom, Sweden, Germany, United States, France, Belgium, Ireland, Italy, Denmark, Puerto Rico, Canada
Kaohsiung Veterans General Hospital.

Unknown

Clinical Epidemiology Cohort Study for Patient Living With HIV

HIV-1 Infection

Taiwan
Merck Sharp & Dohme LLC

Completed

Activity of MK-8504 in Anti-retroviral-naïve, Human Immunodeficiency Virus 1 (HIV-1) Infected Participants (MK-8504-002)

HIV-1 Infection

Germany, United Kingdom
ANRS, Emerging Infectious Diseases

Completed

Lipopeptide Immunisation With GTU-multiHIV Trial

HIV-1 Infection

France
AbbVie

Completed

The Effectiveness of Dual Therapy (Lopinavir/Ritonavir + LamivudinE) in Treatment-Experienced HIV Infected Patients in the Russian Federation (SIMPLE)

HIV-1 Infection
Emory University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Researching Alveolar Macrophage Improvements With Supplements in HIV (RAISe)

HIV-1 Infection

United States
Fundación Huésped
Ministry of Science and Technology,Argentine; National AIDS and STD programme... and other collaborators

Completed

Darunavir/Ritonavir + Lamivudine Versus Darunavir/Ritonavir +Emtricitabine/Tenofovir in Naïve HIV-1 Infected Subjects (ANDES)

HIV-1 Infection

Argentina
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Dolutegravir Plus Lamivudine Dual Therapy in Treatment Naïve HIV-1 Patients

HIV-1 Infection

United States, Puerto Rico
Michael Hoelscher
German Federal Ministry of Education and Research; ANRS, Emerging Infectious... and other collaborators

Completed

A Trial to Confirm a Sustained Virological Suppression Defined as HIV-RNA <50 Copies/ml of 3 Different Doses of Fozivudine in Context to a Standard Zidovudine Based Antiretroviral Therapy Regimen (FATI-01)

HIV-1 Infection

Côte D'Ivoire, Tanzania

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