Clinical Trials on Health Subjects in United Kingdom

Total 32058 results

Allecra

Completed

Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)

Healthy Subjects

United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate if ID-085 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects

Healthy Subjects

United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-389949 in Healthy Subjects

Healthy Subjects

United Kingdom
Inotrem
Richmond Pharmacology Limited

Completed

Safety, Tolerability and Pharmacokinetic Profiles of MOTREM (LR12) in Healthy Male Subjects

Healthy Subjects

United Kingdom
Katarina Kos
University of Exeter

Terminated

Incretin and KATP Channels

Healthy Subjects

United Kingdom
Actelion

Completed

A Study to Assess the Safety and Pharmacokinetics of Lucerastat (OGT 923) in Healthy Subjects

Healthy Subjects

United Kingdom
Actelion

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Lucerastat (CDP923) After Multiple Dosing in Healthy Subjects

Healthy Subjects

United Kingdom
AstraZeneca

Completed

To Assess Safety, Tolerability and Pharmacodynamics of Intravenous MEDI8111 After Single Ascending Doses.

Healthy Subjects

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effects of Single Ascending Doses of ASP1707 in Healthy Young Japanese Male Subjects

Healthy Subjects

United Kingdom
LEO Pharma

Completed

LEO 32731 - A Study in Healthy Male Subjects

Healthy Subjects

United Kingdom
Daiichi Sankyo, Inc.
Quotient Sciences

Completed

A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Healthy Subjects

Healthy Subjects

United Kingdom
Heptares Therapeutics Limited

Completed

Comparison of Blood Levels of HTL0016878 From an Oral Capsule and an Oral Solution

Healthy Subjects

United Kingdom
Heptares Therapeutics Limited

Completed

Measurement of HTL0016878 in Cerebrospinal Fluid

Healthy Subjects

United Kingdom
Helsinn Healthcare SA
Quotient Sciences

Completed

A Study In Healthy Male Volunteers Designed To Investigate How A Radiolabelled Medicine Is Broken Down And Removed From The Body

Healthy Subjects

United Kingdom
Idorsia Pharmaceuticals Ltd.

Terminated

A Study to Evaluate if AC-084 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects

Healthy Subjects

United Kingdom
Egalet Ltd

Completed

Open Label Study to Assess the Pharmacokinetics of Intranasal Ketorolac Tromethamine Following Fluticasone Propionate in Healthy Subjects

Healthy Subjects

United Kingdom
Tetraphase Pharmaceuticals, Inc.
PRA Health Sciences

Completed

Phase 1, Safety and Bronchopulmonary PK Study in Healthy Volunteers (BAL)

Healthy Subjects

United Kingdom
Boston Pharmaceuticals

Completed

Study to Determine the Single and Repeat Dose Pharmacokinetics, Food Effect, Proton Pump Inhibitor (PPI) Drug Interaction, Safety and Tolerability of Oral Prototype Formulations of BOS172767 in Healthy Subjects

Healthy Subjects

United Kingdom
Curadim Pharma Co., Ltd.

Unknown

A First-in-human Phase 1 Study of CP1050

Healthy Subjects

United Kingdom
AstraZeneca

Completed

A Phase I Study to Assess PK of AZD7986 Alone & With Verapamil, Itraconazole or Diltiazem in Healthy Subjects

Healthy Subjects

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Investigate the Effect of Oral Doses of Pilocarpine on Salivary Secretion and Static Pupillometry in Healthy Subjects

Healthy Subjects

United Kingdom
Eli Lilly and Company

Completed

The Effects of Urinary pH Changes on an Investigational Compound in Healthy Subjects

Healthy Subjects

United Kingdom
Bristol-Myers Squibb

Completed

Comparability DE vs CD-CHO1

Healthy Subjects

United Kingdom
Chong Kun Dang Pharmaceutical

Completed

Evaluation of the Safety and Tolerability of CKD-508 in Healthy Subjects

Healthy Subjects

United Kingdom
GlaxoSmithKline

Withdrawn

A Study to Compare Two Paracetamol Tablets

Healthy Subjects

United Kingdom
Leatherhead Food Research
University of Sussex

Completed

The Effect of Sensory-enhanced Beverages on Satiety Following Repeated Exposures

Healthy Subjects

United Kingdom
American Medical Systems
Quintiles, Inc.

Completed

JetTouch Injection System to Deliver Saline Into the Bladder Wall of Healthy Volunteers

Healthy Subjects

United Kingdom
Exeltis France
Insud Pharma

Completed

Benznidazole Absorption, Metabolism and Excretion Study

Healthy Male Subjects

United Kingdom
AstraZeneca

Completed

A Study to Assess the Pharmacodynamic Effect of Single Doses of AZD9977 in Healthy Male Subjects

Healthy Subjects | Pharmacodynamics

United Kingdom
GlycoMimetics Incorporated
Quotient Sciences

Completed

A Study in Healthy Volunteers to Investigate How Much Test Medicine [14C]-Uproleselan is Taken up by the Body When Administered Directly Into the Vein (IV)

Healthy Subjects

United Kingdom
Egalet Ltd

Completed

Assessment of Nasal Deposition and Clearance of Ketorolac Solution Administered Using the Valois Nasal Spray Device

Healthy Subjects

United Kingdom
Zeria Pharmaceutical

Completed

Mass Balance and Metabolism Study of 14C-Z-215

Healthy Male Subjects

United Kingdom
Ono Pharmaceutical Co. Ltd

Completed

A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers

Healthy Adult Subjects

United Kingdom
Astellas Pharma Inc

Completed

A Study to Evaluate Cardiovascular Interactions Between Mirabegron and Tamsulosin

Healthy Subjects | Pharmacokinetics | Cardiovascular

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Compare the Amount of Drug in the Blood After a Single Tablet EC905 Containing Solifenacin and Tamsulosin is Taken by Healthy Males Compared to Separate Tablets of Solifenacin and Tamsulosin

Healthy Subjects | Pharmacokinetics | EC905

United Kingdom
Ono Pharmaceutical Co. Ltd

Completed

A Human Mass Balance Study to Determine the Total Recovery of Radioactivity in Urine and Faeces Following a Single Oral Dose of 14C Radiolabelled ONO-4053

Healthy Adult Male Subjects

United Kingdom
Ono Pharmaceutical Co. Ltd

Terminated

A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers

Healthy Adult Subjects

United Kingdom
AstraZeneca
Eli Lilly and Company

Completed

Electrophysiological Effects of a Single 10 μg Dose of Exenatide on the 12-Lead Electrocardiogram QT Interval in Healthy Subjects

Healthy Subjects

United Kingdom
UCB Biopharma S.P.R.L.

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of UCB0942 in Healthy Japanese and Caucasian Subjects

Healthy Japanese and Caucasian Subjects

United Kingdom
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 After Single Ascending Doses to Healthy Males

Healthy Subjects | Pharmacokinetics | Tolerability | Safety

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP6294 Administered Intravenously or Subcutaneously in Healthy Young Male and Female Subjects

Healthy Subjects | Pharmacokinetics of ASP6294

United Kingdom
Astellas Pharma Europe B.V.

Terminated

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP2205 in Healthy Young Males and Females and Elderly Females and to Evaluate the Effect of Food on the Pharmacokinetics of a Single Dose of of ASP2205

Healthy Subjects | Pharmacokinetics of ASP2205

United Kingdom
Astellas Pharma Europe B.V.

Completed

Absolute Bioavailability Study With Ipragliflozin

Healthy Subjects | Bioavailability of Ipragliflozin

United Kingdom
AstraZeneca

Completed

Study to Assess the Bioequivalence Between Ticagrelor Orodispersible Tablets and Ticagrelor Immediate-release Tablets in Japanese Subjects

Pharmacokinetics | Bioequivalence | Healthy Japanese Subjects

United Kingdom
Astellas Pharma Europe B.V.

Completed

Drug to Drug Interaction Study With Ipragliflozin and Furosemide

Healthy Subjects | Pharmacokinetics of Ipragliflozin

United Kingdom
MedImmune LLC

Completed

Safety and Tolerability of MEDI9314 as Single Ascending Dose in Healthy Subjects

Healthy Subjects | Safety

United States, United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Pharmacokinetics, Metabolism and Excretion Routes of ASP3652 in Man, After Administration of 14C Radio Labeled ASP3652

Healthy Subjects | Pharmacokinetics of ASP3652

United Kingdom
Alvotech Swiss AG
Iqvia Pty Ltd

Completed

A Study to Investigate the PK, Safety, and Tolerability Between AVT05, US and EU Simponi® in Healthy Adult Participants

Healthy Adult Subjects

New Zealand, United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate How Tamsulosin (at 1 Dose) and Solifenacin (at 2 Different Doses) Are Taken up From the Intestine, Distributed Through the Body and Eliminated From the Body When Administered in Combination as a Single Tablet (Called EC905)

Healthy Subjects | Pharmacokinetics | EC905 | Multiple Dose

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Multiple Doses of Gemfribozil on a Single Dose of ASP3652, and to Assess the Effects of Multiple Doses of ASP3652 on a Single Dose of Repaglinide in the Body of Healthy Subjects

Healthy Subjects | Drug-Drug Interaction (DDI)

United Kingdom

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