Clinical Trials on Health Impairment

Total 89988 results

Northwestern University
National Cancer Institute (NCI)

Completed

The "Light for the Brain" Study

Depression | Quality of Life | Fatigue | Sleep | Hematopoietic Stem Cell Transplantation | Cognitive Impairments

United States
National Cheng-Kung University Hospital

Completed

Hand Training Device For Cognitive Care

Mild Cognitive Impairment (MCI) | Healthy Elderly

Taiwan
Idorsia Pharmaceuticals Ltd.

Recruiting

A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of a Single Dose of Cenerimod

Healthy | Hepatic Impairment

Portugal, Hungary
Mitsubishi Tanabe Pharma America

Completed

Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Hepatic Impairment

Healthy | Hepatic Impairment

Japan
Astellas Pharma Global Development, Inc.

Completed

A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of ASP2215

Healthy | Hepatic Impairment

United States
FUJIFILM Toyama Chemical Co., Ltd.
Celerion

Completed

PK Study of T-817 in Subjects With Hepatic Impairment

Healthy | Hepatic Impairment

United States
MDVI, LLC

Completed

Pharmacokinetics of Favipiravir in Volunteers With Hepatic Impairment

Healthy | Hepatic Impairment

United States
Yale University
University of Florida; University of Western Ontario, Canada; Harvard University and other collaborators

Completed

A Psychosocial Program Impact Evaluation in Jordan

Stress, Psychological | Mental Health Impairment

United States
Mental Health Services in the Capital Region, Denmark
The Peer partnership association

Completed

Paths to Everyday Life - a Community-based Peer Support Intervention (PEER)

Mental Health Disorder | Mental Health Impairment | Peer Group | Problems Psychosocial

Denmark
Takeda

Recruiting

A Study of TAK-279 in Adults With or Without Liver Damage

Healthy Volunteers | Hepatic Impairment

United States
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

Germany, Poland, Slovakia
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Completed

GP681 in Volunteers With Hepatic Impairment Compared With Healthy Volunteers

Healthy Volunteers | Hepatic Impairment

China
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate Pharmacokinetics (PK) and Safety of Oral Mobocertinib in Participants With Moderate or Severe Hepatic Impairment (HI) and Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed in People With Liver Dysfunction

Healthy Volunteers | Hepatic Impairment

United States
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

A Pharmacokinetics and Tolerability Study of Fedratinib in Subjects With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
Pfizer

Completed

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of PF-06651600 in Subjects With Hepatic Impairment and Healthy Volunteers

Hepatic Impairment | Healthy Participants

United States
Bristol-Myers Squibb

Not yet recruiting

Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Hepatic Impairment | Healthy Participants
Bristol-Myers Squibb

Not yet recruiting

A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Investigate the Effect of Mild and Moderate Hepatic Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate ASP0367 in Participants With Mild/Moderate Hepatic Impairment Compared to Participants With Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
Celgene

Completed

Evaluate the Pharmacokinetics of CC-220 in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared With Healthy Subjects

Healthy Volunteers | Hepatic Impairment

United States
Turku University Hospital
European Commission; Ocuspecto Oy

Unknown

Assessing Neurovisual Function in Patients With Cognitive Impairment

Glaucoma | Healthy | Mild Cognitive Impairment | Glaucoma and Mild Cognitive Impairment

Finland
University of Hawaii

Recruiting

Natives Engaged in Alzheimers Research - 'Ike Kupuna (NEAR)

Mild Cognitive Impairment | Subjective Cognitive Impairment

United States
Pfizer

Completed

STUDY OF PF-06882961 IN PARTICIPANTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIREMENT

Healthy Volunteers | Hepatic Impairment

United States
Takeda

Completed

A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

United States, Hungary
Idorsia Pharmaceuticals Ltd.

Completed

The Effect of Reduced Liver Function on Selatogrel Pharmacokinetics

Healthy Subjects | Hepatic Impairment

Germany
ObsEva SA

Completed

Safety and Pharmacokinetics Study of Linzagolix in Female Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment | Healthy Participants

United States
Takeda

Completed

A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954

Healthy Volunteers | Hepatic Impairment

Czechia, Slovakia
Jewish General Hospital

Active, not recruiting

Risk for Short-term Adverse Events in Older Emergency Department Users

Older People | Health Care | Health Impairment | Evaluations

Canada
The University of Hong Kong
Haven of Hope Hospital; The Social Innovation and Entrepreneurship Development...

Completed

Tablet-based Interactive Games in Elderly With Cognitive Impairment and Persons With Intellectual Disability

Intellectual Disability | Technology | Cognitive Impairments

Hong Kong
Linkoeping University

Completed

Digital Support for People With Cognitive Impairment

Stroke | Brain Injuries | Cognitive Impairments

Sweden
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Breast Cancer | Cognitive Impairments

United States
Ono Pharma USA Inc
Ono Pharmaceutical Co. Ltd

Completed

An Open-label, Single-dose, Intravenous Administration Study of ONO-2745/CNS 7056 in Subjects With Chronic Hepatic Impairment

Healthy | Hepatic Impairment

United States
VA Office of Research and Development

Completed

rTMS for Emotional Difficulties in Verterans (rTMS)

Depression | PTSD | Anxiety | Mental Health | Psychosocial Impairment | rTMS

United States
XtremeVRI AG
Aristotle University Of Thessaloniki; Klinik Hirslanden, Zurich; Greek Alzheimer...

Completed

Cognitive/Physical Computer-Game Blended Training With Personalized Brain Network Activation Technology for the Elderly (AlterniityAR)

Healthy | Mild Cognitive Impairment, So Stated | Mild Dementia
Aristotle University Of Thessaloniki
Greek Alzheimer's Association and Related Disorders

Completed

Cognitive/Physical Computer-Game Blended Training of Elderly: Neuroscientific LLM Studies (LLM-AUTH)

Healthy | Mild Cognitive Impairment, So Stated | Mild Dementia
Pfizer

Completed

A STUDY TO COMPARE THE PHARMACOKINETICS OF PF-06835919 IN PARTICIPANTS WITH AND WITHOUT HEPATIC IMPAIRMENT

Hepatic Impairment | Healthy Participants

Czechia, Slovakia, Belgium
Pfizer

Completed

Effect Of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of PF-06865571 In Subjects With Hepatic Impairment and in Healthy Subjects

Healthy Volunteers | Hepatic Impairment

United States
Fondazione Don Carlo Gnocchi Onlus
University of Milano Bicocca

Completed

ABILITY - TelerehABILITation: TechnologY-enhanced Multi-domain at Home Continuum of Care Program

Dementia | Alzheimer Disease | Cognitive Impairments
Team Foods Colombia S.A.
Biopolis S.L.

Unknown

Study to Evaluate the Effect of a Vegetal Oil on Cognitive Impairment

Alzheimer Disease | Cognitive Impairments

Spain
ElMindA Ltd

Unknown

Post Hoc Analysis and Clinical Data Collection for Subjects Tested With Brain Network Activation (BNA™) Technology

Healthy | Cognitive Impairment | Neurological Disorder

United States
Jewish General Hospital

Active, not recruiting

Older Emergency Department Users and Short-term Adverse Events at the Index Visit

Hospitalization | Adverse Event | Health Impairment

Canada
Eisai Inc.

Completed

Phase 0 Study in Healthy, Hepatic and Renal Impaired Subjects to Obtain Plasma for Lenvatinib Protein Binding

Hepatic Impairment; Renal Impairment

United States
H. Lundbeck A/S

Completed

Pharmacokinetics Properties of Single Oral Dosing of Lu AE58054 in Subjects With Hepatic Impairment (Mild and Moderate) and in Healthy Subjects

Heptic Impairment

Germany
Chong Kun Dang Pharmaceutical
Choline Alfoscerate Re-evaluation Consortium (57 pharmaceutical companies)

Not yet recruiting

A Clinical Trial to Evaluate the Efficacy and Safety of Choline Alfoscerate in Vascular Cognitive Impairment Patients

Vascular Cognitive Impairment

Korea, Republic of
King's College London

Unknown

White Matter Connections and Memory: the STRATEGIC Study (STRATEGIC)

Stroke | Cognitive Impairment | Memory Impairment
Idorsia Pharmaceuticals Ltd.

Completed

The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics

Healthy Subjects | Hepatic Impairment

Germany, Poland
Acerta Pharma BV
AstraZeneca

Completed

Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite

Hepatic Insufficiency | Healthy Subjects | Hepatic Impairment

United States
Instituto de Medicina Molecular João Lobo Antunes
Fundação para a Ciência e a Tecnologia

Completed

Impact of Physical Activity in Vascular Cognitive Impairment ( AFIVASC ) (AFIVASC)

Vascular Cognitive Impairment

Portugal
Region Skane
Lund University; Berry Lab

Completed

Effect of Nordic Berries on Cognitive Function, Cardiometabolic Risk Markers and Gut Microbiota in Adults With Mild Cognitive Impairment (MINDBERRY)

Memory Impairment | Cognitive Impairment, Mild

Sweden

Clinical Trials on Health Impairment

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