Clinical Trials on Healthy Subjects in South Africa

Total 285 results

Biogen

Completed

Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers

Healthy Adult Subjects | Healthy Elderly Subjects

United States
Harokopio University
Hellenic Republic Ministry of Development; Jotis S.A. Food Industry

Completed

Prebiotic Effect of a Jelly Containing Short Chain Fructo-Oligosaccharides and Sideritis Euboea Extract

Healthy Adult Subjects

Greece
NeuShen Therapeutics

Not yet recruiting

First-into-human Study of NS-136 in Healthy Subjects

Healthy Subjects

Australia
Tavotek Biotherapeutics

Active, not recruiting

Study of TAVO101 in Healthy Volunteers

Healthy Subjects

Australia
GlaxoSmithKline

Completed

GW823296 Repeat Dose Study In Healthy Male And Female Subjects

Healthy Subjects

Australia
Auzone Biological Technology Pty Ltd
TIGERMED AUSTRALIA PTY LIMITED; CMAX Clinical Research Pty Ltd

Completed

A Study of TTYP01 in Healthy Adult Subjects

Healthy Adult Subjects

Australia
Protagonist Therapeutics, Inc.

Completed

Pharmacokinetics of PN-232 in Healthy Volunteers

Healthy Subjects

Australia
Trinomab Biotech Co., Ltd.
TIGERMED AUSTRALIA PTY LIMITED

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TNM002 in Healthy Adults

Healthy Adult Subjects

Australia
Hoffmann-La Roche

Completed

A Study in Healthy Male Subjects to Investigate the Comparability of Pharmacokinetics of the Fixed-Dose Combination of Pertuzumab and Trastuzumab Administered Subcutaneously Using a Handheld Syringe or Using the On-Body Delivery System

Healthy Male Subjects

Australia, New Zealand
GlaxoSmithKline

Completed

A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects

Healthy Subjects | Anaemia

Australia
Boehringer Ingelheim

Completed

Comparison of the Bioavailability of Diclofenac in a Combination Product (Diclofenac 2% + Capsaicin 0.075% Topical Gel) With Two Diclofenac Only Products, Diclofenac Mono Gel 2% and Voltarol® 12 Hour Emulgel 2.32% Gel, in Healthy Volunteers

Healthy

South Africa
Immtech Pharmaceuticals, Inc

Terminated

Randomized, Double-Blind Phase 1 Safety and Tolerability Study of Pafuramidine Maleate (DB289) in Healthy Subjects

Healthy

South Africa
Crossject

Completed

Bioavailability Study of Midazolam Administered as a Solution by Conventional Syringe or ZENEO®

Healthy

South Africa
Actavis Inc.

Withdrawn

Pivotal Bioequivalence Study of Exemestane 25 mg Tablets Under Fasting Conditions in Healthy Subjects

Healthy

South Africa
NeuroVive Pharmaceutical AB

Completed

A Study to Compare the Bioavailability and Pharmacokinetics of Cyclosporine After Intravenous Administration of NEUROSTAT®, a CREMOPHOR® EL-free Lipid Emulsion, and SANDIMMUNE® Injection (a Suspension of Cyclosporine in CREMOPHOR® EL) in Healthy Volunteers

Healthy

South Africa
Boehringer Ingelheim

Completed

Bioequivalence of a Fixed Dose Combination Tablet Containing 400 mg Ibuprofen and 60 mg Pseudoephedrine-HCl Compared to Two Film Coated Fixed Dose Combination Tablets RhinAdvil(R)(200 mg Ibuprofen and 30 mg Pseudoephedrine-HCl) Administered in Healthy Subjects

Healthy Volunteers

South Africa
Pfizer

Completed

Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Healthy Children Aged 15 Months to 17 Years

Healthy Subjects

United States
Boehringer Ingelheim

Completed

To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another Tablet

Healthy

South Africa
London School of Economics and Political Science
University of Witwatersrand, South Africa

Recruiting

Improved Access to Quality Care and Healthcare Use

Health, Subjective | Health Knowledge, Attitudes, Practice | Health Care Utilization

South Africa
PATH
The Emmes Company, LLC

Completed

Safety and Immunogenicity Study of Trivalent P2-VP8 Subunit Rotavirus Vaccine in Adults, Toddlers and Infants

Healthy

South Africa
Mitsubishi Tanabe Pharma Corporation

Completed

Safety and Immunogenicity of MT-5625 in Healthy Adults, Toddlers and Infants

Healthy

Australia, South Africa
University of South Carolina
U.S. Army Medical Research and Development Command

Completed

Dietary Seaweed and Early Breast Cancer: A Randomized Trial

Seaweed Associated Changes in Healthy Subjects

United States
Nestlé

Terminated

Effect of a Starter Formula With Synbiotics on Stool Microbiota in Infants After Normal or Caesarean Section Delivery

Healthy Full Term Infants

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 70 in Healthy Male Subjects

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Comparison of Two Insulin Aspart Formulations in Healthy Volunteers

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 50 in Healthy Male Subjects

Healthy | Diabetes

South Africa
GlaxoSmithKline

Completed

Effect Of Rilapladib (SB-659032) On Platelet Aggregation

Atherosclerosis | Healthy Subjects

Australia
University of KwaZulu
The ELMA Foundation; KwaZulu Natal Department of Health

Completed

An Evaluation of the Effectiveness of e-IMCI Implementation in Primary Health Care Clinics in South Africa.

Primary Health Care | Child Health | Clinical Practice Guidelines

South Africa
GlaxoSmithKline

Completed

To Evaluate Safety, Tolerability, Pharmacokinetics, And Food Effect Of Single Doses Of GSK945237 In Healthy Subjects

Healthy Subjects | Infections, Bacterial

Australia
University of Cape Town
University of Oxford; Orion Corporation, Orion Pharma

Completed

Single-dose Novel Selective alpha2c Antagonist Pharmaco-MRI Study in Healthy Volunteers (SNAP_MRI)

Healthy Volunteer

South Africa
Alvotech Swiss AG

Active, not recruiting

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase Study Conducted in Healthy Volunteers

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
Statens Serum Institut
Bill and Melinda Gates Foundation; Aurum Institute; Leiden University Medical... and other collaborators

Recruiting

First-in-Human Trial of the Novel Tuberculosis Vaccine Candidate, H107e/CAF®10b (nTB-01)

Healthy

South Africa
University of KwaZulu
University of California, San Francisco; Centers for Disease Control and Prevention and other collaborators

Completed

Effectiveness of an HIV-adapted IMCI Training and Supervision Programme for Community Health Workers

Infant Feeding Practices | Prevention of Mother-to-child Transmission of HIV | Antenatal Health Care Utilization | Postnatal Health Care Utilization

South Africa
University of Cape Town
National Research Foundation of South Africa

Completed

Randomised Trial of Two Educational Intervention for Improving Evidence-based Practice Knowledge, Atttitudes and Practice (OTEBP)

Health Knowledge, Attitudes, Practice

South Africa
University of Maryland, College Park
National Institute of Mental Health (NIMH); Medical Research Council, South...

Completed

Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa (Siyakhana)

Substance-Related Disorders | Depression | Tuberculosis | Hiv | Mental Health Disorder | Mental Disorder | Health Care Utilization | Treatment Adherence and Compliance | Social Stigma | Attitude of Health Personnel | Community Health Workers | Health Care Delivery

South Africa
University of Cape Town

Completed

Health System Dynamic & Resource Requirement in a South African COVID-19 Field Hospital

COVID-19 Pandemic | Low-Income Population | Global Health | Health Resources | Field Hospitals | Health Systems

South Africa
Haemonetics Corporation

Completed

Direct Oral Anticoagulant Assay Detection & Classification Study for the TEG 6S System

DOAC Eligible Subjects

United States
Innovations for Poverty Action
Bill and Melinda Gates Foundation; U.S. National Science Foundation; Broadening... and other collaborators

Completed

Evaluation of Impacts of Access to Credit and Loan Size for Microcredit Clients in South Africa

Depression | Stress | Mental Health

South Africa
IGM Biosciences, Inc.

Terminated

Evaluation of IGM-6268 in Healthy Adults and Patients With Mild to Moderate COVID-19

COVID-19 | Healthy Volunteers

South Africa
City University of Hong Kong
Stanford University; Harvard University

Completed

International REACH Forgiveness Intervention

Mental Health Wellness

Colombia, Indonesia, South Africa, Ukraine
North-West University, South Africa
GlaxoSmithKline; Novartis; Pfizer; Boehringer Ingelheim; Medical Research Council; Medical... and other collaborators

Active, not recruiting

The African-PREDICT Study (PREDICT)

Cardiovascular Diseases | Hypertension | Health Risk Behaviors | Arterial Stiffness | Young | Renin Hypertension

South Africa
Amsterdam UMC, location VUmc
Syddansk Universitet, Denmark; Stichting Alexander (the Netherlands); Aalborg... and other collaborators

Recruiting

YoPA - A Youth-centred Participatory Action (YoPA)

Physical Activity | Sleep | Health Promotion

Denmark, South Africa, Netherlands, Nigeria
Eastern Virginia Medical School
Gilead Sciences; United States Agency for International Development (USAID); FHI... and other collaborators

Active, not recruiting

Project Engage: Oral PrEP Acceptability

Adherence, Medication | Acceptability of Health Care

South Africa, Zimbabwe
Pfizer

Completed

Confirming The Sitaxsentan Dose In Patients Undergoing Heart Surgery (FCAD02)

Cardiac Surgery Subjects | Subjects Undergoing CABG and/or Cardiac Valve Replacement

United States
Boston University
National Institute of Mental Health (NIMH); Africa Health Research Institute

Completed

Life Plans Intervention Study

HIV/AIDS | Health Knowledge, Attitudes, Practice | Chronic HIV Infection

South Africa
University of California, San Francisco
Johns Hopkins University; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Rapid Research in Diagnostics Development for TB Network (R2D2 Kids) and Assessing Diagnostics At POC for TB in Children (ADAPT for Kids)

Tuberculosis | Diagnostics | Global Health

Mozambique, South Africa, Uganda
Desmond Tutu HIV Foundation
Karolinska Institutet; University of North Carolina, Chapel Hill; ViiV Healthcare and other collaborators

Completed

Bidirectional, Upbeat Communication and Differentiated, Distanced Care for Young People (BUDDY)

HIV Infections | Covid19 | Health Care Utilization | Gender-based Violence

South Africa
Novartis Vaccines
GlaxoSmithKline

Completed

Study to Identify Factors Influencing Access of Pregnant Women and Their Infants to Local Healthcare Systems

Pregnancy, Newborn Health

Dominican Republic, Mozambique, Panama, South Africa
Hospira, now a wholly owned subsidiary of Pfizer

Completed

A Safety and Efficacy Study of Dexmedetomidine in ICU Patients Requiring Continuous Sedation

Mechanically Ventilated and Intubated Subjects

United States, Australia, Argentina, Brazil, New Zealand

Clinical Trials on Healthy Subjects in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Australia

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Rare Diseases

Drug Interventions

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