Clinical Trials on Healthy Volunteers (Non-alcoholic Steatohepatitis) in Japan

Total 104 results

Novo Nordisk A/S

Completed

A Research Study Looking at How the Medicine NNC0194-0499 Behaves in Japanese and Non-Asian Men

Non-alcoholic Steatohepatitis

Japan
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of MT-3995 in Patients With Non-Alcoholic Steatohepatitis(NASH)

NASH

Japan
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy of Tropifexor (LJN452) in Patients With Non-alcoholic Steatohepatitis (NASH) (FLIGHT-FXR)

Non-alcoholic Steatohepatitis (NASH)

Belgium, Germany, Taiwan, Austria, United States, Spain, Korea, Republic of, Argentina, Australia, Italy, Japan, Singapore, Netherlands, Slovakia, France, Canada, India
AstraZeneca

Recruiting

A Trial to Learn How Safe AZD9550 is in People With Type 2 Diabetes Who Are Overweight or Obese (CONTEMPO)

Non-alcoholic Steatohepatitis (NASH)

Austria, Germany, Japan, Sweden
Regeneron Pharmaceuticals

Recruiting

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Non-Alcoholic Steatohepatitis (NASH) in Adult Participants at Increased Genetic Risk for This Condition (NASHGEN-2)

Non-alcoholic Steatohepatitis (NASH) | Metabolic Dysfunction Associated Steatohepatitis (MASH)

United States, Korea, Republic of, Puerto Rico, Japan
Boehringer Ingelheim

Completed

A Study to Test Safety and Efficacy of BI456906 in Adults With Non-alcoholic Steatohepatitis (NASH) and Fibrosis (F1-F3)

Non-alcoholic Steatohepatitis (NASH)

United States, Spain, Korea, Republic of, United Kingdom, Australia, Canada, Singapore, Germany, Italy, Malaysia, China, France, Japan, Taiwan, Netherlands, Austria, Israel, New Zealand, Poland, Hong Kong, Belgium, Czechia, Greece, Hu... and more
AstraZeneca

Completed

A Study to Evaluate the Safety and Efficacy of Cotadutide Given by Subcutaneous Injection in Adult Participants With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis (PROXYMO-ADV)

Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

United States, Austria, Italy, Thailand, Germany, Korea, Republic of, Japan, Malaysia, New Zealand, Spain, Taiwan, Turkey, Australia, Israel, Argentina, Canada, Greece, South Africa, United Kingdom, France
Novartis Pharmaceuticals

Terminated

Efficacy, Safety and Tolerability of the Combination of Tropifexor & Licogliflozin and Each Monotherapy, Compared With Placebo in Adult Patients With NASH and Liver Fibrosis. (ELIVATE)

Non Alcoholic Steatohepatitis (NASH)

United States, South Africa, Spain, Germany, Italy, Taiwan, Canada, Korea, Republic of, Singapore, Bulgaria, Estonia, Mexico, Japan, Denmark, United Kingdom, Colombia, Brazil, Belgium, Russian Federation, Puerto Rico, Chile, Argen... and more
Novo Nordisk A/S

Active, not recruiting

Research Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non-alcoholic Steatohepatitis (NASH)

Non-alcoholic Steatohepatitis

Spain, Denmark, Taiwan, Korea, Republic of, Australia, Canada, India, Singapore, United States, Turkey, Poland, Italy, Belgium, Puerto Rico, United Kingdom, Malaysia, Germany, Portugal, Bulgaria, Czechia, France, Greece, Japan, Russian...
Novo Nordisk A/S

Completed

Investigation of Efficacy and Safety of Three Dose Levels of Subcutaneous Semaglutide Once Daily Versus Placebo in Subjects With Non-alcoholic Steatohepatitis.

Non-alcoholic Steatohepatitis | Hepatobiliary Disorders

United States, Russian Federation, United Kingdom, Denmark, Sweden, Netherlands, Austria, Belgium, Spain, France, Bulgaria, Canada, Australia, Greece, Japan, Finland, Puerto Rico
Novo Nordisk A/S

Recruiting

Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH) (ESSENCE)

Non-alcoholic Steatohepatitis

United States, Korea, Republic of, Australia, Taiwan, Italy, Israel, Canada, Netherlands, Czechia, Malaysia, Spain, Denmark, China, United Kingdom, Singapore, Japan, Puerto Rico, Portugal, Switzerland, Ireland, Belgium, Romania, Ger... and more
Yokohama City University
EA Pharma Co., Ltd.

Completed

Efficacy and Safety of Elobixibat in Combination With Cholestyramine for Nonalcoholic Fatty Liver Disease

Nonalcoholic Steatohepatitis | Nonalcoholic Fatty Liver

Japan
Tokyo Medical University

Recruiting

Innovative Liver Elasticity, Attenuation, and Dispersion Ultrasound Study (iLEAD)

Nonalcoholic Steatohepatitis | Elastography | Ultrasound

United States, Korea, Republic of, Germany, Italy, China, France, Japan, United Kingdom
AstraZeneca

Completed

A Two-part Single and Multiple Dose Study to Assess the Safety , Pharmacokinetics and Effects of AZD3293 in Healthy Japanese Young and Elderly Volunteers

Healthy Japanese Young and Elderly Male and Non-fertile Female Volunteers

Japan
Yokohama City University

Active, not recruiting

Efficacy and Safety of Guanabenz for Nonalcoholic Fatty Liver Disease

Nonalcoholic Steatohepatitis | Nonalcoholic Fatty Liver

Japan
Celgene

Terminated

Study to Evaluate the Efficacy and Safety of CC-90001 in Participants With Non-alcoholic Steatohepatitis (NASH) and Liver Fibrosis

Liver Cirrhosis | Non-alcoholic Fatty Liver Disease

United States, Spain, Australia, Korea, Republic of, Canada, Germany, France, Japan, United Kingdom, Poland
Merck Sharp & Dohme LLC

Terminated

A Study of MK-3655 in Individuals With Pre-cirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-3655-001)

Nonalcoholic Steatohepatitis

Korea, Republic of, United States, Argentina, Australia, Canada, Chile, China, Colombia, France, Germany, Greece, Hong Kong, Israel, Italy, Japan, Malaysia, Mexico, New Zealand, Puerto Rico, Russian Federation, Spain, Sweden, Taiwan, ...
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) in Participants With Nonalcoholic Steatohepatitis (NASH) (SYNERGY-NASH)

Nonalcoholic Steatohepatitis

United States, Spain, Japan, United Kingdom, Belgium, France, Italy, Israel, Mexico, Poland
Gilead Sciences

Terminated

Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis (STELLAR-3)

Nonalcoholic Steatohepatitis

Hong Kong, United States, Spain, United Kingdom, Australia, Taiwan, Belgium, Canada, India, Japan, Korea, Republic of, Singapore, Puerto Rico, France, Israel, Austria, Germany, Italy, Malaysia, New Zealand, Mexico, Poland, Switzerland, Netherlan... and more
Ono Pharmaceutical Co. Ltd

Completed

Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability and PK of ONO-2910 in Japanese and Caucasian Subjects

Healthy Volunteers

Japan
Affinivax, Inc.

Completed

Single Ascending Dose of ASP3772 Study in Japanese Healthy Male and Female Adults, and Single Ascending Dose Study of ASP3772 in Comparison With PPSV23 in Japanese Elderly Male and Female Subjects

Healthy Volunteers

Japan
Kitasato University
Aetas Pharma Co. Ltd.

Completed

Multiple Dose Escalation Study of M201-A in Healthy Japanese Subjects

Healthy Volunteers

Japan
Takeda

Completed

A Study to Evaluate the Bioequivalence (BE) and the Food Effect of TAK-438ASA Tablet

Healthy Volunteers

Japan
Eli Lilly and Company

Completed

A Study of Evacetrapib in Healthy Japanese Participants

Healthy Volunteers

Japan
Nihon Pharmaceutical Co., Ltd

Completed

Phase I/II Clinical Trial of NPF-08 in Healthy Volunteers

Healthy Volunteers

Japan
Danone Japan

Completed

A Clinical Study for Evaluating the Safety of a Plant Sterol-enriched Fermented Dairy Product in Japanese Healthy Adults

Healthy Volunteers

Japan
UCB Japan Co. Ltd.

Completed

Multiple-dose Study of Levetiracetam Injection in Japanese and Caucasian Healthy Males

Healthy Volunteers

Japan
Gilead Sciences
Novo Nordisk A/S

Active, not recruiting

Study of Semaglutide, and Cilofexor/Firsocostat, Alone and in Combination, in Adults With Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (WAYFIND)

Nonalcoholic Steatohepatitis

United States, Spain, Australia, France, Japan, Puerto Rico, Canada
Astellas Pharma Inc
FibroGen

Completed

Pharmacokinetic Study of ASP1517 With Kremezin®

Healthy Volunteers

Japan
Bristol-Myers Squibb

Terminated

Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

United States, Germany, Taiwan, United Kingdom, Spain, Argentina, Brazil, France, Israel, Italy, Japan, Korea, Republic of, Belgium, Canada, Puerto Rico, Switzerland
Ono Pharmaceutical Co. Ltd

Completed

Multiple-dose Study of FOY-305 in Japanese Healthy Adult Male Subjects

Healthy Volunteers

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Bioequivalence Study of ASC-01 Placebo (Aripiprazole 0 mg/Sertraline 100 mg) and Sertraline Tablet in Healthy Male Subjects

Healthy Volunteers

Japan
Astellas Pharma Inc

Completed

Bioequivalence Evaluation of a New and Current Tablet of ASP015K

Healthy Volunteers

Japan
Eli Lilly and Company

Completed

A Study of Insulin Peglispro in Healthy Male Japanese Participants

Healthy Volunteers

Japan
Astellas Pharma Inc

Completed

ASP8825 - A Study to Investigate the Food Effect on the Pharmacokinetics of ASP8825

Healthy Volunteers

Japan
Hamamatsu University

Completed

Effects of Statins on the Pharmacokinetics for Midazolam in Healthy Volunteers (H-17-21)

Healthy Volunteers

Japan
Astellas Pharma Inc

Completed

Safety, Tolerability and Pharmacokinetic Study of ASP1517 in Healthy Non-elderly Male Volunteers

Healthy Volunteers

Japan
Gilead Sciences

Terminated

Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (STELLAR-4)

Nonalcoholic Steatohepatitis

United States, Spain, Hong Kong, Canada, Belgium, Australia, Taiwan, India, Japan, Korea, Republic of, Singapore, United Kingdom, Israel, Puerto Rico, France, New Zealand, Germany, Austria, Italy, Mexico, Poland, Switzerland
Eisai Co., Ltd.

Completed

A Study to Assess the Safety and Tolerability of E8001 in Healthy Male Participants

Healthy Volunteers

Japan
Yuji KUMAGAI
Aetas Pharma Co. Ltd.

Completed

First-in-Human Dose Escalation Study of M201-A in Healthy Japanese Subjects

Healthy Volunteers

Japan
Astellas Pharma Inc

Completed

Study to Evaluate the Safety and Tolerability of ASP8062 in Healthy Japanese Male and Female Subjects

Healthy Volunteers

Japan
Allergan

Completed

Inter-rater and Intra-rater Reliability Study of the Global Eyelash Assessment Scale for Assessment of Overall Eyelash Prominence

Healthy Volunteers

Japan
Ono Pharmaceutical Co. Ltd

Completed

Single Ascending Dose Study to Assess the Safety, Tolerability, PK and PD of ONO-4685 in Japanese and Caucasian Healthy Adult Male Subjects

Healthy Volunteers

Japan
Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate Skin Irritation and Photo Irritation of JNJ 10229570-AAA on Intact Skin of Japanese Healthy Male Participants

Healthy Volunteers

Japan
Eisai Co., Ltd.

Completed

A Study to Assess the Safety and Tolerability of E6742 in Japanese Healthy Adult Participants

Healthy Volunteers

Japan
Takeda

Completed

Phase 3 Study to Evaluate the Acid-Inhibitory Effect of Multiple Oral Doses of Vonoprazan (TAK-438)

Healthy Volunteers

Japan
Zeria Pharmaceutical

Completed

A Healthy Subject Study With Z-360 and Placebo

Healthy Volunteers

Japan
Astellas Pharma Inc

Completed

A Study to Assess Effect of Exercise Program Provided by Smartphone Application on the Body Composition

Healthy Volunteers

Japan
Takeda

Completed

A Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability of TAK-123 After Intravenous Infusion in Japanese Healthy Adult Male Participants

Healthy Volunteers

Japan
Takeda

Completed

Single-Dose Study of MT203

Healthy Volunteers

Japan

Clinical Trials on Healthy Volunteers (Non-alcoholic Steatohepatitis) in Japan

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