Clinical Trials on Healthy Lifetime Non-smokers

Total 212 results

University of Miami
James and Esther King Biomedical Research Program

Terminated

Evaluation of Acute and Subacute Effects of Nicotine Free Electronic Cigarette(NCFE) Vapors

Healthy Lifetime Non-smokers

United States
Universitätsmedizin Mannheim

Completed

Multiple Breath Washout (MBW) Using Sulfur Hexafluoride Reference Values and Influence of Anthropometric Parameters

Healthy Subjects | Non-smokers | Smokers
Helsinn Healthcare SA
Celerion

Completed

Study to Evaluate the Food Effect of Single-dose Bioavailability of Pracinostat in Healthy Adult Subjects (HVFE)

Healthy Volunteers | Non-smokers | Moderate to Heavy Smokers

United States
Helsinn Healthcare SA

Completed

Evaluate the Effects of Itraconazole and Ciprofloxacin on Single-Dose PK of Pracinostat in Healthy Nonsmoking Subjects

Healthy Volunteers | Non-smokers

United States
Duke University
National Institutes of Health (NIH)

Completed

Memory and Picture Viewing Study (MPVS)

Healthy | Brain Reactivity of Non-smokers Undergoing fMRI Scanning

United States
Rockefeller University

Completed

Genetic Basis of Odor Discrimination

Non-smokers

United States
Medicines for Malaria Venture
Q-Pharm Pty Limited; Trident Clinical Research Pty Ltd; Queensland Institute...

Completed

A Pilot Study to Test Activity of Antimalarial Drugs Against an Induced Malaria Infection in Healthy Volunteers

Healthy | Non-smokers

Australia
GlaxoSmithKline

Completed

Oral Tolerability Of Two Nicotine Dosage Forms

Healthy Volunteer Smokers
Clinical Nutrition Research Center, Illinois Institute...

Completed

Matrix on Fruit Constituent Bioavailability (FRT)

Healthy Non-smoker

United States
Contract Research Organization el AB
Swedish Match AB

Completed

4 mg Nicotine Polacrilex Gum and Swedish Portion Snus (SMWS06)

Healthy Subjects | Smokers

Sweden
GlaxoSmithKline

Completed

A Single Dose Bioequivalence Study OfTwo Formulations Of Nicotine Lozenges

Healthy Volunteer Smokers
Universita degli Studi di Catania
Lega Italiana Anti Fumo; Arbi Group Srl

Completed

A Structured Protocol to Evaluate Efficacy and Safety of a Popular Electronic Nicotine Delivery Device (E-Cigarette) Efficacy and Safety of a Popular Electronic Nicotine Delivery Device (E-Cigarette)

Smoking Cessation | Healthy Smokers

Italy
Imperial College London
GlaxoSmithKline

Withdrawn

Biomarkers of iNOS Activity in COPD, Asthma, Healthy Control

Healthy Smokers | Healthy Non-smokers | Patients With Mild Asthma | Patints With COPD (GOLD II)

United Kingdom
Universita degli Studi di Catania
Lega Italiana Anti Fumo; Arbi Group Srl

Completed

Efficacy and Safety of an Electronic Nicotine Delivery Device (E-Cigarette) Without Nicotine Cartridges

Smoking Cessation | Healthy Smokers

Italy
Universita degli Studi di Catania
Lega Italiana Anti Fumo; Arbi Group Srl

Completed

Efficacy and Safety of an Electronic Nicotine Delivery Device (E-Cigarette)

Smoking Cessation | Healthy Smokers

Italy
University Hospital, Clermont-Ferrand
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement and other collaborators

Completed

Effects of Curcumin on Vascular Reactivity (CURCUMIN)

Healthy Volunteers (Middle-aged Smokers)

France
Hiroshima University
Wakunaga Pharmaceutical Co., Ltd.

Completed

Antioxidant Effect of Aged Garlic Extract

Heavy Smoker or Non-smoker

Japan
Roswell Park Cancer Institute
National Institute on Drug Abuse (NIDA); National Cancer Institute (NCI)

Completed

Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers (ENDS)

Current Smoker | Healthy Subject | Cigarette Smoker

United States
University Hospital, Montpellier

Completed

Repair, Remodeling and Regeneration of the Bronchial Epithelium of COPD Patients (RRR)

COPD | Smokers | Heathy Volunteers

France
Imperial College London
AstraZeneca

Withdrawn

Markers for Chronic Obstructive Pulmonary Disease (COPD)

COPD Patients | Current Smokers | Healthy Non-smokers

United Kingdom
Pierre Fabre Medicament

Completed

Assessment of V0018 2.5 mg Effect on Craving

Healthy Highly Dependant Smokers

France
Scott Kollins, PhD
National Institute on Drug Abuse (NIDA)

Completed

Nicotine, Non-Smokers With and Without ADHD, and Genetics Study (NNSG)

ADHD | Non-smoker

United States
Pierre Fabre Medicament

Completed

Nicotine Patch - Bioequivalence Study

Healthy Smokers

France
University of the Balearic Islands
Hospital Son Llatzer

Unknown

Smoking Cessation in Hospitalized Patients Using an App (NoFumo+)

Smoking Cessation | CBT | Hospitalized Smokers | Mhealth

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Physical Activity in Promoting Smoking Cessation in African Americans

Current Smoker | Healthy Subject

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Evaluation of the Effect of a Nasal Allergen Challenge With Dermatophagoides Farinae Extract on Nasal Airway Inflammation in Allergic Individuals, Comparing E-cigarette Users to Cigarette Smokers and Non-smokers. (Mitey Nose)

Healthy Participants | Tobacco Smokers

United States
Pierre Fabre Medicament

Completed

Nicotine Patch Bioequivalence Study

Healthy Smokers

France
Pierre Fabre Medicament

Completed

Nicotine Patch - Multidose Bioequivalence Study

Healthy Smokers

France
Pierre Fabre Medicament

Completed

Pilot Pharmacokinetic Study of New Nicotine Lozenge Formulations

Healthy Smokers

France
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Terminated

Range of Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Otherwise Healthy Smokers

Healthy Smokers

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model (Kitty Nose)

Tobacco Smoking | Healthy Participants | E-cigarette Smokers

United States
University of Miami

Completed

Effect of Whole Body Periodic Acceleration on Airway Endothelial Function

Healthy | Asthma | Smokers

United States
Medical University of Vienna

Recruiting

The Effect of Hyperoxia and Hypoxia on Fluorescence Lifetime Imaging Ophthalmoscopy in Healthy Subjects- a Randomized, Double Blind, Crossover Study

To Investigate the Effect of 100% Oxygen Breathing on Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) in Healthy Subjects

Austria
Inje University

Completed

The Effects of Montelukast on Smokers With Asthma

Asthmatic Smokers | Non-asthmatic Smokers

Korea, Republic of
Imperial College London
AstraZeneca

Withdrawn

Effect of Symbicort on HAT and HDAC in Sputum Macrophages of COPD

Chronic Obstructive Pulmonary Disease (COPD) | Age Matched Healthy Volunteers (Non-smokers)

United Kingdom
Tianjin Medical University Cancer Institute and...

Not yet recruiting

To Evaluate the Efficacy and Safety of Anrotinib Hydrochloride Capsule in Postoperative Non-pCR Patients With Non-small Cell Lung Cancer

Event-free Lifetime

China
ResMed
Eden Sleep

Completed

Snore Positive Airway Pressure Trial

Non-Apnoeic Snorers

New Zealand
Ayşegül İşler Dalgıç
Horizon

Not yet recruiting

Metaverse-Based Healthy Life Program for Youth (MetaYouth)

Stress, Emotional | Health Risk Behaviors | Health-Related Behavior | Healthy Lifestyle | Physical Inactivity | Healthy Nutrition | Healthy Eating Index | Non Communicable Diseases

Turkey
Isra University

Completed

Effect Of Deep Breathing Exercises In Smokers

Healthy Smokers
Pneumacare Ltd

Completed

SLP Model Development in the Diagnosis of COPD Patients (SLPCOPD)

COPD | Healthy Smoker

United Kingdom
National Institute on Aging (NIA)

Recruiting

Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

Healthy Volunteers | Non-Healthy/Non-Frail | Frail

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer (BLCIO)

Current Smoker | Lung Adenocarcinoma | Stage IV Non-Small Cell Lung Cancer | Squamous Cell Lung Carcinoma | Cigarette Smoker

United States
THIM - die internationale Hochschule für Physiotherapie
Vrije Universiteit Brussel

Completed

Effectivity of Slackline-Training in Physiotherapy

Healthy Volunteers | Persons With no Known Significant Health Problems

Switzerland
Pfizer

Completed

Evaluation of Varenicline Safety, Tolerability, Pharmacokinetics and Pro-Cognitive Effects in Healthy Elderly Non-Smoking Subjects

Healthy | Non-Smoking

United States
The University of Queensland

Active, not recruiting

International Lung Screen Trial (ILST) (ILST)

Neoplasms | Respiratory Tract Diseases | Lung Diseases | Neoplasms by Site | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Non-small Cell Lung Cancer | Smokers at Risk of Lung Cancer

Australia, Canada
Shanghai General Hospital, Shanghai Jiao Tong University...
Duke University; Rutgers University; Tsinghua University

Completed

Effect of Short-term Portable Air Purifier Use on Occupant Health Indicators

Non-smoking, Healthy Adults

China
Agios Pharmaceuticals, Inc.

Completed

Study to Evaluate the Pharmacokinetics, Safety, and QTc Effect of AG-348 in Healthy Subjects of Japanese Origin and Non-Asian Origin

Healthy | Japanese | Non-Asian

United States
BeiGene

Completed

Phase 1 Study to Investigate Effect of Rifampin and Itraconazole on the Pharmacokinetics of BGB-3111 in Healthy Subjects

Healthy Volunteers: Asian, Non-Asian

United States
Guangzhou Institute of Respiratory Disease

Not yet recruiting

Exploration of Non-invasive High-frequency Oscillations in Human-machine Asynchrony in Healthy Subjects

Healthy Subjects | Non-invasive Ventilation

China
Kantonsspital Baselland Bruderholz

Unknown

Influence of Erythropoietin on Bone Marrow Microenvironment

Healthy Men and Non- Pregnant Women

Switzerland

Clinical Trials on Healthy Lifetime Non-smokers

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