- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00736203
Memory and Picture Viewing Study (MPVS)
Study Overview
Status
Detailed Description
Thirty six non-smokers will undergo functional magnetic resonance imaging (fMRI) scanning. During scanning participants will complete the n-back task-a measure of working memory-and the cue-reactivity task-a measure of responses to smoking cues. Before scanning, participants will complete a training session where they will be familiarized with the tasks.
All participants will have to pass a screening visit in order to be included in the study.
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
North Carolina
-
Durham, North Carolina, United States, 27705
- Duke University Medical Center
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- generally healthy
- right-handed non-smokers
- between the ages of 18-55
- an expired CO concentration of 5 ppm or less; or a negative urine cotinine test of 100 ng/mL or less (to confirm a non-smoker)
- having smoked < 50 cigarettes in their lifetime
Exclusion Criteria:
- inability to attend all sessions
- significant health problems (hypertension, emphysema, seizure disorder, history of significant heart problems)
- use of psychoactive medications
- use of any tobacco or nicotine containing products
- current alcohol or drug abuse
- use of illegal drugs as measure by a urine drug screen
- presence of conditions that would make MRI unsafe (pacemaker, metallic implants
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
---|
A
non-smokers
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
brain reactivity
Time Frame: 3 weeks
|
3 weeks
|
Collaborators and Investigators
Sponsor
Collaborators
Investigators
- Principal Investigator: Joseph McClernon, PhD, Duke University
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- Pro00008250
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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