Clinical Trials on Healthy Volunteer, Down Syndrome

Total 3934 results

Genentech, Inc.

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of MHAB5553A in Healthy Volunteers

Healthy Volunteer

Canada
BGI-Shenzhen

Completed

Calorie Restriction Intervention Induces Enterotype-associated BMI Loss in Nonobese Individuals (CRDI)

Healthy Volunteer

China
Pfizer

Completed

THE EFFECT OF MULTIPLE DOSES OF PF-06835919 ON THE PHARMACOKINETICS OF A SINGLE ORAL MIDAZOLAM DOSE IN HEALTHY PARTICIPANTS

Healthy Volunteer

Belgium
Nanjing Sanhome Pharmaceutical, Co., Ltd.

Unknown

A Food-Effect Study of SHC014748M in Healthy Subjects

Healthy Volunteer

China
Nanjing Sanhome Pharmaceutical, Co., Ltd.

Unknown

Pharmacokinetic Study of SH-1028 Tablets in Healthy Subjects Under Fasting and Fed Conditions

Healthy Volunteer
Shionogi

Completed

Effect of Food and Calcium on Pharmacokinetics of a Single Dose of S-888711 in Healthy Adult Volunteers

Healthy Volunteer

United States
University Hospital, Grenoble

Terminated

Characterization of Independant Task Neural Correlates of Different Levels of Mental Workload (CARACOg)

Healthy Volunteer

France
Aravive, Inc.

Completed

A Phase 1 AVB-S6-500 Safety and Tolerability Study

Healthy Volunteer

United States
pH Pharma

Completed

PK/PD, Safety and Tolerability of PHP-201 Topical Eye Drop in Korean and Japanese Healthy Subjects

Healthy Volunteer

Korea, Republic of
Aquinox Pharmaceuticals (Canada) Inc.

Completed

Oral AQX-1125 and Combination Oral Contraceptive Drug-Drug Interaction Study (DDI-COC)

Healthy Volunteer

Netherlands
SK Life Science, Inc.

Completed

A Study of the Abuse Liability Potential of Cenobamate in Recreational Drug Users

Healthy Volunteer

United States, Canada
First Affiliated Hospital of Zhejiang University
Ascletis Pharmaceuticals Co., Ltd.

Completed

Bioequivalence Study of Ritonavir Versus NORVIR in Healthy Chinese Subjects (RTV)

Healthy Volunteer

China
Hoffmann-La Roche

Terminated

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of RO6889678 and the Combination of RO6889678 With Ritonavir in Healthy Participants

Healthy Volunteer

Netherlands
Duke University
Scion NeuroStim

Completed

Caloric Stimulation on Cerebral Blood Flow

Healthy Volunteer

United States
Genentech, Inc.

Completed

A Study of High Dose MHAA4549A in Healthy Volunteers

Healthy Volunteer

Canada
Hoffmann-La Roche

Completed

A Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of RO6864018 in Male, Healthy, Asian Participants

Healthy Volunteer

Singapore
Genentech, Inc.

Completed

A Study to Investigate the Effect of GDC-0449 on the QT/QTc Interval in Healthy Female Subjects

Healthy Volunteer
Hoffmann-La Roche

Completed

Basmisanil Positron Emission Tomography Study in Japanese Volunteers

Healthy Volunteer

United Kingdom
Genentech, Inc.

Completed

A Study in Healthy Volunteers to Assess the Relative Bioavailability and Tolerability of Two Crenezumab Formulations Following Administration of a Single Subcutaneous Dose

Healthy Volunteer

United States
Genentech, Inc.

Completed

A Study Evaluating the Effect of Formulation on the Bioavailability of Ipatasertib in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Multiple Ascending-Dose Study of RG7625 in Healthy Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Drug-Drug Interaction Study of Ketoconazole, Rifampicin and Ritonavir-Boosted Atazanavir With Single-Dose RO5093151 in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study on The Effect of Multiple Doses of Activated Charcoal on The Pharmacokinetics of a Single Dose of RO4995819

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Pharmacokinetic And Bioavailability Study of Intravenous Danoprevir in Healthy Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study Investigating the Bioavailability of a High Concentration Liquid Formulation Versus a Reference Lyophilized Formulation of Gantenerumab in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Human Proof of Concept Study for [11C]-RO5011232 as Radiotracer and Study of the Binding of RO4917523 to Human mGlu5 Brain Receptor at Steady-State in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Bioequivalence Study Comparing Pirfenidone Tablet and Capsule Dosage Forms in Healthy Adult Participants

Healthy Volunteer

United States
Genentech, Inc.

Completed

A Study of Lebrikizumab in Healthy Japanese and Caucasian Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of Danoprevir in Healthy Volunteers And Patients With Hepatic Impairment

Healthy Volunteer

Slovakia, United States, Czech Republic
Hoffmann-La Roche

Completed

A Study of RO5267683 in Healthy Subjects

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Single-Center Study of RO5508887 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Relative Bioavailability Study of Danoprevir and Ritonavir in Healthy Volunteers

Healthy Volunteer

New Zealand
Hoffmann-La Roche

Completed

A Study to Evaluate The Effects of Two Different Meal Types, Omeprazole And Ranitidine On Danoprevir Pharmacokinetics When Coadministered With Ritonavir in Healthy Volunteers

Healthy Volunteer

United States
Genentech, Inc.

Completed

A Study of MHAA4549A to Assess Safety And Pharmacokinetics in Healthy Volunteers

Healthy Volunteer

Canada
Hoffmann-La Roche

Completed

A Study of RO6799477 in Healthy Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of The Excretion Balance, Pharmacokinetics and Metabolism of A Single Oral Dose of [14C]-Labeled RO4917523 in Healthy Male Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of Single Dose RO6811135 in Healthy Volunteers

Healthy Volunteer

United States
Genentech, Inc.

Completed

A Study of MCAF5352A in Healthy Volunteers

Healthy Volunteer

Canada
Hoffmann-La Roche

Completed

A Study of the Combination of Multiple Doses of RO5285119 With a Single Dose of Risperidone in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A 28-Day Pharmacokinetics Study of RG1662 in Healthy Male Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of The Abuse Liability Potential of RO4917838 in Recreational Drug Users

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of RO5024048 in Japanese and Caucasian Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study to Investigate the Effects of Rifampicin on the Pharmacokinetics of Aleglitazar in Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Pharmacokinetics Study of Aleglitazar in Combination With Digoxin in Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of Drug-Drug Interaction Between Danoprevir Coadministered With Low-Dose Ritonavir and Tenofovir Disoproxil Fumarate or Atazanavir

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Aspirin in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of The Relative Bioavailability of Ritonavir-Boosted Danoprevir Fixed Dose Combination Tablets in Healthy Volunteers

Healthy Volunteer

New Zealand
Hoffmann-La Roche

Completed

A Study of Drug-Drug Interaction Between Danoprevir/Low-Dose Ritonavir and Raltegravir in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A 2-Part Study to Evaluate the Safety of Supra-Therapeutic Doses of RO4602522 and to Investigate the Effect of RO4602522 on the QTc Interval

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of RO4917838 With Rosuvastatin in Healthy Volunteers

Healthy Volunteer

France

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