Clinical Trials on Healthy Volunteer, Down Syndrome

Total 3921 results

Hoffmann-La Roche

Completed

A Study of RO6926496 in Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of the Effect of Memantine on Pharmacokinetics, Safety and Tolerability of Single Dose RO5313534 in Healthy Volunteers, and the Effect of RO5313534 on Safety and Tolerability of Steady State Memantine

Healthy Volunteer

France
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Effects of Mipomersen on Lipid and Lipoprotein Metabolism in Healthy Subjects

Healthy Volunteer

United States
Hoffmann-La Roche
Trophos SA

Completed

A Study of the Excretion Balance of Radiocarbon and the Pharmacokinetics and Metabolic Profile of TRO19622 (Olesoxime)

Healthy Volunteer
Genentech, Inc.

Completed

A Study to Evaluate the Pharmacokinetics and Safety of Cobimetinib in Volunteers With and Without Liver Damage

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Pharmacodynamic Study to Evaluate Neutrophil Distribution Kinetics and Function Following Single-Dose RoActemra/Actemra (Tocilizumab) in Healthy Volunteers

Healthy Volunteer

United Kingdom
AbbVie

Completed

Pharmacokinetics and Safety of the Co-administration of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 in Healthy Chinese Subjects

Healthy Volunteer

China
Genzyme, a Sanofi Company

Completed

A Phase I Study of the Pharmacokinetic Variability and Relative Bioavailability of the Phase 3 and Common Blend Formulations of Eliglustat in Healthy Adult Subjects

Healthy Volunteer

United States
Meiji Seika Pharma Co., Ltd.
Dong-A Pharmaceutical

Completed

Bioequivalence Study Evaluating the Pharmacokinetics of DMB-3111 and Trastuzumab in Healthy Japanese Male Adults

Healthy Volunteer

Japan
Regado Biosciences, Inc.

Completed

Safety, Tolerability and PK/PD of RB006 in a Healthy Volunteer SAD (SC101)

Healthy Volunteer

United States
Achaogen, Inc.
Defense Medical Research and Development Program

Completed

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ACHN-975 in Healthy Volunteers

Healthy Volunteer

United States
S*BIO

Completed

A Single and Multiple-Dose Study of SB1578

Healthy Volunteer

United States
Pfizer

Completed

Radiolabeled [14C]PF-02341066 Study To Investigate The Absorption, Metabolism And Excretion In Healthy Male Volunteers

Healthy Volunteer

United States
GlaxoSmithKline

Completed

An Evaluation of Two Novel Nasal Strip Prototypes on Nasal Patency

Healthy Volunteer

United Kingdom
Angela Kashuba, PharmD
Merck Sharp & Dohme LLC

Completed

Study to Characterize the Pharmacokinetics of Raltegravir in the Gastrointestinal (GI) Tract of Healthy Male Volunteers

Healthy Volunteer

United States
AstraZeneca

Completed

Safety, Tolerability, and Pharmacokinetics of AZD7268 After Single Ascending Oral Doses in Healthy Subjects

Healthy Volunteer

United States
GlaxoSmithKline
Shionogi

Completed

A Study to Evaluate the Effect of Antacid and Multivitamin and Mineral Tablet on the Study Drug GSK1349572 (DDI)

Healthy Volunteer

United States
AstraZeneca

Completed

Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single Doses of AZD8566.

Healthy Volunteer

United Kingdom
AstraZeneca

Completed

Determine the Effect of Multiple Doses of AZD7325, CYP Study (CYP)

Healthy Volunteer
Syndax Pharmaceuticals

Completed

A Study to Examine the Effect of Omeprazole, Famotidine, and an Acidic Beverage on the Pharmacokinetics of Entinostat in Healthy Adult Subjects

Healthy Volunteers | Volunteers | Normal Volunteers | Human Volunteers

United States
Syndax Pharmaceuticals

Completed

Study to Determine the Effect of the Timing of a Meal on the Pharmacokinetics of Entinostat

Healthy Volunteers | Volunteers | Normal Volunteers | Human Volunteers

United States
International Bio service

Not yet recruiting

Bioequivalence Study of Generic Celecoxib 200 mg Capsules

Healthy Volunteer
International Bio service

Not yet recruiting

Bioequivalence Study of Empagliflozin 25 mg Film-coated Tablets in Healthy Thai Volunteers

Healthy Volunteer
Disc Medicine, Inc

Recruiting

A Study of DISC-3405 in Healthy Volunteers

Healthy Volunteer

United States
National Cancer Institute (NCI)

Recruiting

Collection of Peripheral Blood Mononuclear Cells (PBMCs) From Healthy People for the Expansion of T Cells for Adoptive Cell Therapy

Healthy Volunteer

United States
National Institute on Deafness and Other Communication...

Recruiting

Normal Values in Hearing and Balance Testing

Healthy Volunteer

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Collection of Data and Samples From Healthy Donors for Use in Translational Research

Healthy Volunteer

United States
National Institute of Mental Health (NIMH)

Recruiting

Studies of Blood Flow to the Brain During Thought

Healthy Volunteer

United States
National Human Genome Research Institute (NHGRI)

Completed

Patient Provider Communication and Interaction in a Virtual Clinical Setting

Healthy Volunteer

United States
AbbVie

Completed

A Study to Assess the Mass Balance of [14C] ABBV-552 in Healthy Male Participants Following Single Oral Dose Administration

Healthy Volunteer

United States
University Hospital, Grenoble

Completed

Study of Neurophysiological Correlates of the Link Between Perception and Action (PSM_EEG)

Healthy Volunteer

France
Hospices Civils de Lyon

Completed

Diagnostic Performance of Gastric Ultrasound in Children (QUALIGASTR)

Healthy Volunteer

France
Vanda Pharmaceuticals
Mayo Clinic

Completed

Effects of Tradipitant on Satiation, Gastric Volume, Gastric Accommodation, and Gastric Emptying in Healthy Volunteers

Healthy Volunteer

United States
AbbVie

Completed

A Study to Assess Adverse Events and How Single and Multiple Ascending Doses of ABBV-903 Move Through the Body in Healthy Adults

Healthy Volunteer

United States
Hanmi Pharmaceutical Company Limited

Completed

Study to Compare the Safety, Pharmacokinetics and Pharmacodynamics of HIP1802 to HGP1705 in Healthy Volunteers

Healthy Volunteer

Korea, Republic of
Hanmi Pharmaceutical Company Limited

Completed

Study to Compare the Safety, Pharmacokinetics and Pharmacodynamics of HIP2105 to RLD2104 in Healthy Volunteers

Healthy Volunteer

Korea, Republic of
Revolo Biotherapeutics

Completed

Safety, Tolerability, and Pharmacokinetics of IRL201104 in Healthy Volunteers

Healthy Volunteer

United States
E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd.

Completed

A First-in-Human Study of QY101 Ointment in Adult Subjects

Healthy Volunteer

China
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug Exposure of Single Ascending Doses of BMS-986369 and the Effect of Food on the BMS-986369 in Healthy Participants

Healthy Volunteer

United States
Mitsubishi Tanabe Pharma America Inc.

Completed

Relative Bioavailability and Drug-drug Interaction Study With MT-7117 and a Proton Pump Inhibitor (MT-7117 BA DDI)

Healthy Volunteer

Germany
Mitsubishi Tanabe Pharma America Inc.

Completed

Definitive QT Study With MT-8554 (MT-8554 DQT)

Healthy Volunteer

United Kingdom
Insmed Incorporated

Completed

A Study to Investigate the Effects of Brensocatib on QT Interval in Healthy Participants

Healthy Volunteer

United States
Takeda

Completed

A Study of TAK-951 in Healthy Adults

Healthy Volunteer

United States
Moleculin Biotech, Inc.

Completed

Study to Assess the Safety and Pharmacokinetics of WP1122 in Healthy Volunteers

Healthy Volunteer

United Kingdom
Hospices Civils de Lyon

Completed

Tractography and Diffusion Tensor Imaging of the Human Spinal Cord in Healthy Subjects : Anatomical Atlas (TRACTOCORD)

Healthy Volunteer

France
Supernus Pharmaceuticals, Inc.

Completed

Evaluating the Safety and Relative Bioavailability of Three SPN-817 Treatments (A, B and C) in Healthy Adult Subjects

Healthy Volunteer

Australia
AstraZeneca
Quotient Sciences

Completed

A Study to Investigate the Absolute Bioavailability, Absorption, Metabolism, Distribution and Excretion of [14C]AZD5363 (Capivasertib)

Healthy Volunteer

United Kingdom
AstraZeneca

Completed

Pharmacokinetics, Immunogenicity, Safety and Tolerability of MEDI3506 in Health Chinese Participants

Healthy Volunteer

China
Sage Therapeutics

Completed

A Study to Assess the Electrophysiology, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response Using Magnetic Resonance Imaging of SAGE-718 Using a Ketamine Challenge in Healthy Subjects

Healthy Volunteer

United States
Sage Therapeutics

Completed

Study of SAGE-904 Using a Ketamine Challenge to Evaluate Electrophysiology, Safety, Tolerability, and Pharmacokinetics in Healthy Participants

Healthy Volunteer

United States

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