Clinical Trials on Healthy Volunteer, Muscular Atrophy, Spinal

Total 6375 results

Amgen

Completed

Bioequivalence Study of Denosumab CP4 Drug Product and Commercially Available Denosumab CP2 Drug Product

Healthy Volunteer

United States
Shanghai 10th People's Hospital

Unknown

coMparison Between invAsive and Non-invasive assessmenT on Blood Pressure and Cardiac Function in HealthY Participants (MATCHY)

Healthy Volunteer
Hoffmann-La Roche

Withdrawn

A Study Exmining the Effect of Multiple Doses of Bitopertin on the Single Dose Pharmacokinetics of Midazolam in Healthy Volunteers.

Healthy Volunteer
Celgene

Completed

Radiolabeled Study of CC-220 in Healthy Male Subjects

Healthy Volunteer

United States
Meiji Seika Pharma Co., Ltd.

Completed

A Phase 1 Pharmacokinetic Bioequivalence Study of DMB-3113 and Adalimumab in Healthy Japanese Adult Male Subjects (DMB-3113-1)

Healthy Volunteer

Japan
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Brain Peripheral Benzodiazepine Receptors

Healthy Volunteer

United States
Aquinox Pharmaceuticals (Canada) Inc.
Quotient Clinical

Completed

Phase 1 Absorption Distribution Metabolism and Excretion of AQX-1125 (ADME)

Healthy Volunteer

United Kingdom
Genentech, Inc.

Completed

A Study of the Safety, Tolerability, Pharmacokinetics, and Bioavailability of IV and SC MABT5102A in Healthy Volunteers

Healthy Volunteer
Genentech, Inc.

Completed

A Study to Evaluate the Effect of a Proton-Pump Inhibitor (Rabeprazole) on the Relative Bioavailability of Cobimetinib in Healthy Participants

Healthy Volunteer
Genentech, Inc.

Completed

A Study to Determine the Relative Bioavailability of a Tablet Formulation of GDC-0941 and the Effect of Ketoconazole on the Pharmacokinetics of the GDC-0941 Tablet

Healthy Volunteer

United States
University Hospital, Grenoble

Completed

Anatomic Altas of the Whole Human Body (A2H)

Healthy Volunteer
Hoffmann-La Roche

Completed

A Study of The Effects of Multiple Doses of Ketoconazole on Single Dose Pharmacokinetics of RO4602522 in Healthy Male Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of the Effect of Fluvoxamine on the Pharmacokinetics of RO4917523 in Healthy Volunteers

Healthy Volunteer

France
Genentech, Inc.

Completed

A Bioequivalence Study of Subcutaneous (SC) Lebrikizumab Administered by Needle and Syringe or by Prefilled Syringe With Needle Safety Device (PFS-NSD)

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Single Center Study to Evaluate the Penetration of RO7033877 Into the Lung in Healthy Volunteers

Healthy Volunteer

United States
Genentech, Inc.

Completed

A Drug Interaction Study of GDC-0032 Co-administered With Rifampin or Itraconazole in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO5545965 in Healthy Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of RO5285119 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Study on the Effect of Renal Function on the Pharmacakokinetics of RO5024048 (Parent of Prodrug RO5024048) Following Multiple Oral Dose Administration of RO5024048

Healthy Volunteer

New Zealand, United States
Hoffmann-La Roche

Completed

A Study on the Effects of Valproate on the Pharmacokinetics of RO4917838 in Healthy Volunteers

Healthy Volunteer

France
Genentech, Inc.

Completed

Study to Determine the Effect of Ketoconazole on the Pharmacokinetics of GDC-0980

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Oral Contraceptive Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Phase 1 Clinical Study in Healthy Volunteers to Investigate the Drug-drug Interaction Between Multiple Doses of RO7033877 and Multiple Doses of Colistin Methanesulfonate Sodium (CMS)

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study to Evaluate the Bioequivalence of Tocilizumab Following Subcutaneous Administration Via an Autoinjector (AI 1000-G2) Versus a Pre-Filled Syringe in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Single Dose Study of Radiolabeled RO4602522 in Healthy Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Single-center Study to Investigate How Quickly and to What Extent a Radioactive Dose of RO5285119 is Absorbed, Metabolized and Eliminated From the Body of Healthy Male Volunteers

Healthy Volunteer

Netherlands
Genentech, Inc.

Completed

A Phase I Bioavailability and Pharmacokinetic Study of [14C]-Ipatasertib Single Oral and Intravenous Doses in Healthy Male Subjects

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study on Safety, Pharmacokinetics and Pharmacodynamics of RO5508887 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Phase 1 Study of RO6806127 in Healthy Male Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Two-part, Single-dose, Randomized Study to Evaluate the Safety of Supra-therapeutic Doses of RO7033877 and to Investigate the Effect of RO7033877 on the QTc Interval

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of A High Concentration Liquid Formulation Versus A Lyophilized Formulation of Gantenerumab in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Study of RO4995819 in Healthy Elderly Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of the Effect of RO4917838 on the QTcF Interval in Healthy Volunteers

Healthy Volunteer

United States, France
Hoffmann-La Roche

Completed

A Study of the Effect of RG1662 on Metformin in Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of Bitopertin (RO4917838) in Healthy Male Volunteers

Healthy Volunteer

New Zealand
Hoffmann-La Roche

Completed

A Study on The Effect of Hepatic Impairment on The Pharmacokinetics of RO4917838

Healthy Volunteer

France, Russian Federation
Genentech, Inc.

Completed

A Study of RG7667 in Healthy Volunteers

Healthy Volunteer

United States
Genentech, Inc.

Completed

A Bioavailability and Pharmacokinetic Study of GDC-0032 in Healthy Volunteers

Healthy Volunteer

United States
Genentech, Inc.

Completed

A Study of the Effect of Formulation and Tablet Hardness on the Bioavailability of Pictilisib in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Safety And Pharmacokinetic Study of Setrobuvir Alone and In Combination With Ritonavir-Boosted Danoprevir in Subjects With Mild Hepatic Impairment Compared to Healthy Controls

Healthy Volunteer

Poland, Hungary
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-0941 Following Single Oral Dose Administration in Healthy Male Subjects

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study on the Effect of Food on the Pharmacokinetics of RO5428029 in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study Investigating the Effect of Food and Esomeprazole on the Single Oral Dose Pharmacokinetics of Alectinib (RO5424802) in Healthy Volunteers.

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of RO5190591 (Danoprevir) in Healthy Volunteers

Healthy Volunteer

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Doses of Mipomersen in Japanese Healthy Volunteers

Healthy Volunteer

Germany
University Hospital, Grenoble

Completed

Neuroeconomic Approach of Food Nutritionnal Assesment (NeuroFood)

Healthy Volunteer
Genentech, Inc.

Completed

A Safety, Tolerability, and Pharmacokinetic Study of GDC-3280 in Healthy Participants

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of The Effect of Hepatic Impairment on The Pharmacokinetics of Aleglitazar

Healthy Volunteer

United States
Eli Lilly and Company

Completed

A Study of LY110140 in Healthy Japanese Male Participants

Healthy Volunteer

Japan
Pfizer
ViiV Healthcare

Completed

Study to Estimate the Pharmacokinetics, Bioavailability and Effect of Food on Single Dose Modified-release Lersivirine 500 mg in Healthy Subjects

Healthy Volunteer

Belgium

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