Clinical Trials on Heart Failure, Left Ventricular Dysfunction

Total 9249 results

The Cleveland Clinic

Terminated

STandardized Ultra-conservative Or Physician-directed ICD Programming for Continuous Flow LVAD Support

Heart Failure, Systolic | ICD | Left Ventricular Assist Device

United States
Abbott Medical Devices

Completed

More Options Available With a Quadripolar LV Lead pRovidE In-clinic Solutions to CRT Challenges (MORE-CRT)

Heart Failure | Perioperative/Postoperative Complications | Postoperative Cardiac Complication | Left Ventricular Cardiac Dysfunction | Inappropriate Phrenic Nerve Stimulation

Spain, United Kingdom, Netherlands, France, Israel, Finland, Canada, Belgium, Germany, Italy, India, Poland, Switzerland
NYU Langone Health

Recruiting

Registry of Patients With Takotsubo Syndrome

Tako-tsubo Cardiomyopathy | Takotsubo Cardiomyopathy | Broken Heart Syndrome

United States
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

Preoperative Levosimendan in CABG Patients With Poor LV Function (LICORN)

Coronary Artery Bypass Grafting | Left Ventricular Dysfonction

France
Oussama Wazni
The Cleveland Clinic; Biosense Webster, Inc.

Terminated

Catheter Ablation vs. Medical Therapy in Congested Hearts With AF (CATCH-AF)

Atrial Fibrillation | Congestive Heart Failure | Left Ventricular Failure

United States
University of Minnesota

Completed

Neuron Specific Enolase in Ventricular Assist Device Recipients (NSE-LVAD)

Advanced Heart Failure | Left Ventrucular Assist Device

United States
University of Aberdeen
NHS Grampian

Completed

Pathogenesis of Acute Stress Induced (Tako-tsubo) Cardiomyopathy: Energy Shut-Down or Intense Inflammation? (TERRIFIC)

Tako-tsubo Cardiomyopathy

United Kingdom
Bicetre Hospital

Completed

Hemodynamic Characteristics of Patients With SARS-CoV-2 (PiCCOVID)

COVID-19 | Shock | Acute Respiratory Distress Syndrome | SARS-CoV-2 | Fluid Overload | Coronavirus | Left Ventricular Dysfunction | Acute Circulatory Failure

France
Rigshospitalet, Denmark

Recruiting

Daily Life Activities in Patients Treated With Continuous-Flow Left Ventricular Assist Devices (Act-VAD)

Left Ventricular Failure, Unspecified

Denmark
Nagoya University

Unknown

Eplerenone and Aliskiren Research Targeting Hypertensive Patients With Left Ventricular Hypertrophy (EARTH)

Hypertensive Left Ventricular Hypertrophy

Japan
Bayer

Terminated

Hemodynamic and Echocardiographic Assessment of Riociguat Effects on Myocardial Wall Contractility and Relaxation Kinetics (HEARTWORK)

Hypertension, Pulmonary | Ventricular Dysfunction, Left

United States
Mayo Clinic

Withdrawn

Subcu Administration of CD-NP in Heart Failure Patients With Left Ventricular Assist Device Support (CD-NP/LVAD)

Heart Failure | Left Ventricular Assist Device | Natriuretic Peptide
Massachusetts General Hospital

Recruiting

Diffusion MRI in Heart Failure

Myocardial Infarction | Heart Failure | Left Ventricular Hypertrophy

United States
Imperial College London
British Heart Foundation; Leducq Foundation; Celladon Corporation

Terminated

Investigation of the Safety and Feasibility of AAV1/SERCA2a Gene Transfer in Patients With Chronic Heart Failure (SERCA-LVAD)

Chronic Heart Failure | Patients That Have Received a Left Ventricular Assist Device

United Kingdom
University Hospital of Ferrara

Recruiting

ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing (TREEBEARD)

Atrial Fibrillation | Arrhythmias, Cardiac | Left Bundle-Branch Block | Bundle-Branch Block | Ventricular Fibrillation | Ventricular Tachycardia | Ventricular Dysfunction | Atrioventricular Block | Heart Failure, Systolic | Ventricular Arrythmia | Heart Failure，Congestive | Bradyarrhythmia | Heart Arrhythmia | Reduced... and other conditions

Italy
University of Campania "Luigi Vanvitelli"

Completed

Hyperglycemia in Patients With Takotsubo Syndrome

Takotsubo Cardiomyopathy

Italy
Bayer

Active, not recruiting

A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction (LEPHT)

Hypertension, Pulmonary | Ventricular Dysfunction, Left

Belgium, France, China, Spain, Japan, United States, Singapore, Canada, Switzerland, Austria, Denmark, Germany, Italy, Australia, Czechia, Netherlands, Poland, United Kingdom
Mallinckrodt

Completed

Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery

Hypertension, Pulmonary | Ventricular Dysfunction, Left

Japan
Hiroaki Shimokawa, MD, PhD

Unknown

Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study)

Heart Failure | Coronary Disease | Heart Valve Diseases | Cardiomyopathies | Left Ventricular Hypertrophy

Japan
University of Aberdeen
NHS Lothian; NHS Tayside; NHS Greater Glasgow and Clyde; NHS Lanarkshire; NHS Ayrshire... and other collaborators

Recruiting

Establishing the Incidence of Tako-tsubo Cardiomyopathy in Scotland (STARR)

Myocardial Infarction | Takotsubo Cardiomyopathy

United Kingdom
Rigshospitalet, Denmark

Recruiting

Prognostic Value of BNP in MCS - a 25 Year Follow up Study

Heart Failure | Prognosis | Left Ventricular Assist Device | Durable Mechanical Support Device

Denmark
Elpen Pharmaceutical Co. Inc.

Completed

Clinical Trial in Patients With Hypertension and Left Ventricular Dysfunction

Hypertension | Diabetes Mellitus | Renal Insufficiency | Sleep Apnea | Cardiac Arrhythmias

Greece
Abbott Medical Devices
Thoratec Corporation

Completed

Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Destination Therapy

Cardiomyopathies | Ventricular Dysfunction | Heart Failure, Congestive

United States, Canada
Abbott Medical Devices
Thoratec Corporation

Completed

Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Bridge to Cardiac Transplantation

Cardiomyopathies | Ventricular Dysfunction | Heart Failure, Congestive

United States, Canada
Institut National de la Santé Et de la Recherche...

Unknown

Identification Of Blood Markers For Asymptomatic Ventricular Dysfunction (IBLOMAVED)

Heart Failure

France
Karim WAHBI
Institut de Myologie, France

Unknown

Prospective Becker-Heart-Study (Becker-HS)

Heart Failure | Dilated Cardiomyopathy | Lef Ventricular Dysfunction

France
Brigham and Women's Hospital
Boston Scientific Corporation

Not yet recruiting

Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE (SONIC-PE)

Pulmonary Embolism | Right Ventricular Dysfunction | Right Ventricular Failure
Imperial College London

Completed

Mechanisms and Innovations in Cardiac Resynchronisation Therapy (MIC)

Heart Failure | Left Bundle-Branch Block | Left Ventricular Systolic Dysfunction | Right Bundle-Branch Block | Non-Specific Intraventricular Conduction Defect

United Kingdom
Centre Hospitalier Universitaire Dijon

Completed

LEft Atrial Pacing in Diastolic Heart Failure (LEAD)

Heart Failure With Preserved Ejection Fraction | Atrial Dyssynchrony Syndrome | Left Atrio-ventricular Asynchrony

France
Valentina Puentmann
Bayer; Alcedis GmbH

Recruiting

Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19 (MYOFLAME-19)

Microvascular Angina | Left Ventricular Dysfunction | Vascular Inflammation | Exercise Intolerance | Remodeling, Left Ventricle | Remodeling, Vascular | COVID-19 Associated Cardiac Involvement

Germany, Austria
Seoul National University Hospital

Recruiting

Left Bundle Branch Area Pacing in Heart Failure Patients With Ejection Fraction Below Normal

Left Ventricular Ejection Fraction Less Then or Equal to 50percent

Korea, Republic of
University of Aberdeen

Recruiting

Is There a Genetic Predisposition for Acute Stress-induced (Takotsubo) Cardiomyopathy (GENETIC)

Takotsubo Cardiomyopathy

United Kingdom
Assistance Publique - Hôpitaux de Paris
Fédération Française de Cardiologie

Completed

TAKO-TSUBO Cardiomyopathy and Genetic

Acute Coronary Syndrome | Tako-TSUBO Cardiomyopathy

France
Herlev and Gentofte Hospital
Copenhagen University Hospital, Denmark

Active, not recruiting

Cardiac Structure and Function in Patients With Cystic Fibrosis

Myocardial Infarction | Heart Diseases | Heart Failure | Stroke | Cystic Fibrosis | Heart Failure, Diastolic | Heart Failure, Systolic | Left Ventricular Dysfunction | Cystic Fibrosis-related Diabetes | Cystic Fibrosis Gastrointestinal Disease | Cystic Fibrosis of Pancreas | Cystic Fibrosis, Pulmonary | Cystic...

Denmark
Universitaire Ziekenhuizen KU Leuven

Completed

Pulse Wave Analysis and Velocity in Patients With Chronic Renal Failure: a Cross-sectional Observational Study to Assess Association With Left Ventricular Hypertrophy, Uremic Toxins and Inflammation.

Left Ventricular Hypertrophy | Arterial Stiffness | CHRONIC RENAL FAILURE

Belgium
French Cardiology Society
French Federation of Cardiology

Completed

Evaluation of Left Ventricular Filling Pressures During Exercise (PREFFORT)

Heart Failure With Preserved Ejection Fraction (HFPEF) | Left Ventricular End Diastolic Pressure (LVEDP)

France
Pensionsversicherungsanstalt

Not yet recruiting

Effectiveness of a Resilience-Based Rehabilitation Program for Patients With Coronary Heart Disease

Acute Coronary Syndrome | Takotsubo Cardiomyopathy | Psychological Resilience
Washington University School of Medicine

Completed

Ventricular Assist Device Anti-Factor Xa (VAD ANTIX) Monitoring Study: a Prospective Randomized Feasibility Trial (VAD-ANTIX)

Heparin | Left Ventricular Assist Device | Gastro Intestinal Bleeding | Anticoagulant Therapy | Left Sided Heart Failure | Thrombosis, LVAD | Anti-factor Xa | aPTT

United States
Prolaio

Recruiting

A Noninterventional, Single-Center Feasibility Study to Evaluate Measures of Heart Failure Risk

Heart Failure | Cardiomyopathy, Hypertrophic | Left Ventricular Hypertrophy

United States
Emory University
Children's Healthcare of Atlanta

Withdrawn

Effects of Nesiritide in Pediatric Patients With Heart Failure

Heart Failure | Ventricular Dysfunction | Heart Decompensation
Abbott Medical Devices

Completed

B-Left HF: Biventricular Versus Left Univentricular Pacing With Implantable Cardiac Defibrillator (ICD) Back-Up in Heart Failure Patients

Heart Diseases | Heart Failure | Ventricular Dysfunction

France
Ospedale San Giovanni Bellinzona

Completed

Tako-Tsubo Cardiomyopathy and Cardiac Syndrome X: New Insights Into the Pathophysiology (ENDAUT)

Takotsubo Cardiomyopathy | Syndrome X

Switzerland
University of Campania "Luigi Vanvitelli"

Completed

Sympathetic Heart Innervation in Patients With Tako-Tsubo Cardiomyopathy

Apical Ballooning Syndrome | Nervous System Diseases, Sympathetic

Italy
Merck Sharp & Dohme LLC
Duke Clinical Research Institute

Terminated

The Effect Of Acadesine On Reducing Cardiovascular and Cerebrovascular Adverse Events In Coronary Artery Bypass Graft (CABG) Surgery (Study P05633 AM1)(TERMINATED) (RED-CABG)

Myocardial Infarction | Stroke | Coronary Artery Bypass | Ventricular Dysfunction, Left | Cardiopulmonary Bypass
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Effects of the Sodium-glucose Cotransporter 2 Inhibitors+Sacubitril/Valsartan Therapy in Patients With HFrEF.

Heart Failure | Ventricular Dysfunction | Ventricular Remodeling

Italy
Oslo University Hospital
South-Eastern Norway Regional Health Authority

Unknown

Global Strain and Mechanical Dispersion May Predict Death and Ventricular Arrhythmias Better Than Ejection Fraction

Left Ventricular Function Systolic Dysfunction

Norway, Czechia
Columbia University
GE Healthcare

Completed

COvid-19 LongitUdinal Multiethnic BioImaging Assessment of CARDiovascular Sequelae Registry

Covid19 | Myocarditis | Cardiac Arrhythmia | Cardiac Disease | Left Ventricular Dysfunction

United States
Deborah Ascheim
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation

Heart Failure | Ventricular Dysfunction | Cardiomyopathy

United States
Montreal Heart Institute
Abbott Medical Devices

Recruiting

Transcatheter Mitral Valve Repair for the Treatment of Mitral Valve Regurgitation In Heart Failure (The EVOLVE-MR Trial) (EVOLVE-MR)

Ventricular Remodeling, Left

Canada
University of Glasgow
Pharmacosmos A/S; British Heart Foundation; NHS Greater Glasgow and Clyde

Completed

Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN (IRONMAN)

Chronic Heart Failure | Iron Deficiency | Left Ventricular Systolic Dysfunction

United Kingdom

Clinical Trials on Heart Failure, Left Ventricular Dysfunction

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