Clinical Trials on Heart Valve Replacement in Netherlands

Total 2598 results

St. Antonius Hospital

Completed

Patient Reported Health-Related Quality of Life After Limited Access and Conventional Aortic Valve Replacement (LIAR)

Quality of Life | Aortic Valve Stenosis | Limited Access Aortic Valve Replacement

Netherlands
The Medicines Company

Completed

Open-label, Randomized Trial in Participants Undergoing TAVR to Determine Safety & Efficacy of Bivalirudin vs UFH (BRAVO 2/3)

Transcatheter Aortic Valve Replacement | Aortic Valve Replacement | Severe Aortic Stenosis

Netherlands, Germany, United Kingdom, Canada, France, Italy, Switzerland
Erasmus Medical Center
Roche Diagnostics

Recruiting

ADAPT Transcatheter Aortic Valve Intervention (TAVI & Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI) (ADAPT)

Transcatheter Aortic Valve Replacement | Percutaneous Coronary Intervention

Netherlands
Boston Scientific Corporation

Completed

REPRISE II: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of Lotus™ Valve System

Transcatheter Aortic Valve Replacement

Spain, United Kingdom, Australia, France, Germany, Italy, Netherlands, Sweden, Switzerland
Maastricht University Medical Center
Maastricht University

Unknown

HV Electrophysiology Study In Transcatheter Aortic Valve Implantation Patients (HESITATE)

Transcatheter Aortic Valve Replacement | Transcatheter Aortic Valve Implantation | Left Bundle Branch Block

Netherlands
Population Health Research Institute
Hamilton Health Sciences Corporation

Recruiting

Low INR to Minimize Bleeding With Mechanical Valves Trial (LIMIT)

Bleeding Post-mechanical Valve Replacement | Thromboembolism Post-mechanical Valve Replacement

Canada, Spain, Belgium, Russian Federation, Netherlands, Brazil
Radboud University Medical Center

Active, not recruiting

Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI (APPOSE)

Aortic Valve Stenosis | Aortic Valve Insufficiency | Transcatheter Aortic Valve Replacement | Hemodynamic Monitoring | Acquired Von Willebrand Disease | Heyde's Syndrome

Netherlands
Corcym S.r.l

Terminated

Safety and Effectiveness Study of Perceval S Valve for Extended CE Mark (CAVALIER)

Aortic Valve Replacement

Belgium, Germany, Netherlands, France, Austria, Poland, Switzerland, United Kingdom
Bayer
Janssen Research & Development, LLC

Terminated

Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes (GALILEO)

Transcatheter Aortic Valve Replacement

Belgium, France, Germany, Spain, United States, Switzerland, Canada, Austria, United Kingdom, Korea, Republic of, Denmark, Italy, Netherlands, Poland, Czechia, Sweden, Norway
UMC Utrecht

Terminated

Edwards SAPIEN-3 Periprosthetic Leakage Evaluation Versus Medtronic CoreValve in Transfemoral Aortic Valve Implantation (ELECT)

Periprosthetic Aortic Valve Regurgitation After TAVI

Netherlands
UMC Utrecht

Completed

Normal Values in Stress Echocardiographic Parameters in Patients After Successful Mitral Valve Repair for Organic MR (SEP)

Heart Valve Diseases | Mitral Valve Insufficiency | Diseases of Mitral Valve | Heart; Dysfunction Postoperative, Cardiac Surgery | Heart; Disease, Mitral(Valve)

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Evaluation of Mitral Valve Insufficiency Under General Anesthesia (MITIGATE)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The Effects of 360-degree Virtual Reality on Pre-procedural Anxiety in Patients Awaiting Elective Cardiac Surgery Involving a Sternotomy

Aortic Valve Disease | Cardiac Valve Disease | Mitral Valve Disease | Tricuspid Valve Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The Role of Left Atrial Fibrosis in Mitral Valve Repair Surgery (ALIVE Trial) (ALIVE)

Mitral Regurgitation | Surgery | Cardiac Valve Disease | Mitral Valve Disease | Mitral Valve Surgery | Mitral Valve Repair

Netherlands
Medtronic Cardiovascular

Active, not recruiting

SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial (SMART)

Aortic Valve Stenosis | Aortic Valve Replacement | Symptomatic Aortic Stenosis

United Kingdom, United States, Netherlands, Canada, Israel, Spain, Finland, Denmark, France, Germany, Switzerland, Italy, Portugal
UMC Utrecht
Leiden University Medical Center; The Interuniversity Cardiology Institute... and other collaborators

Terminated

The Dutch Asymptomatic Mitral Regurgitation Trial (Dutch AMR)

Mitral Valve Insufficiency | Diseases of Mitral Valve | Heart; Disease, Mitral(Valve)

Netherlands
Imperial College London
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Unknown

Online Videodensitometric Assessment of Aortic Regurgitation in the Cath-Lab (OVAL)

Heart Valve Diseases | Aortic Valve Insufficiency | Paravalvular Aortic Regurgitation | Regurgitation, Aortic

Netherlands
St. Antonius Hospital

Recruiting

Future Optimal Research and Care Evaluation - Aortic Stenosis (FORCE-AoS)

Severe Aortic Valve Stenosis | Moderate Aortic Valve Stenosis

Netherlands
Erasmus Medical Center

Recruiting

Real-time Pressure Volume Loop Monitoring as a Guide for Enhanced Understanding of Changes in Elemental Cardiovascular Physiology During Therapeutic Strategies Aiming for Hemodynamic Optimization. Cohort II: Structural Heart Interventions (PLUTO-II) (PLUTO-II)

Heart Failure | Aortic Stenosis | Valvular Heart Disease | Mitral Insufficiency | Tricuspid Insufficiency

Netherlands
Edwards Lifesciences

Completed

EDWARDS INTUITY Valve System FOUNDATION Study (FOUNDATION)

Aortic Stenosis | Aortic Valve Disease | Rapid Deployment Valves

Spain, United Kingdom, Austria, Netherlands, Italy, France, Germany, Denmark, Switzerland
Erasmus Medical Center
Daiichi Sankyo, Inc.

Recruiting

Rotterdam EDOXaban Leaflet Evaluation in Patients After Transcatheter Aortic Valve Implantation (REDOX-TAVI)

Aortic Valve Stenosis

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Cerebrovascular EveNts in Patients Undergoing TranscathetER Aortic Valve Implantation With Balloon-expandable Valves Versus Self-expandable Valves. (CENTER)

Aortic Valve Stenosis

Netherlands
St. Antonius Hospital
ZonMw: The Netherlands Organisation for Health Research and Development; Pitié-Salpêtrière...

Recruiting

Personalized, CT-guided Antithrombotic Therapy Versus Lifelong Single Antiplatelet Therapy to Reduce Thromboembolic and Bleeding Events in Non-atrial Fibrillation Patients After Transcatheter Aortic Valve Implantation (POP ATLANTIS)

Severe Aortic Valve Stenosis

Netherlands
Medtronic Bakken Research Center

Completed

Engager Align Post-market Clinical Study

Aortic Valve Stenosis

Netherlands
Keystone Heart

Completed

DEFLECT II: A Study to Evaluate the Safety and Performance of the TriGuard™HDH in Patients Undergoing TAVR

Aortic Valve Stenosis

Netherlands
Erasmus Medical Center

Completed

Manta™ Versus Suture-based Closure After Transcatheter Aortic Valve Implantation Trial (MASH-TAVI)

Aortic Valve Stenosis

Netherlands
St. Antonius Hospital
ZonMw: The Netherlands Organisation for Health Research and Development

Enrolling by invitation

Evaluating Edge-to-edge Transcatheter Tricuspid Valve Repair in Patients With Severe Symptomatic Tricuspid Regurgitation (TRACE-NL)

Cardiac Catheterization | Tricuspid Valve Regurgitation, Nonrheumatic | Heart Failure, Right Sided | Valve Regurgitation, Tricuspid

Netherlands
Erasmus Medical Center
Feops

Recruiting

Addition of Computer Simulations to Minimize Adverse Events After Transcatheter Aortic Valve Implantation (PRECISE_TAVI)

Aortic Valve Stenosis | Bicuspid Cardiac Valve

Netherlands
Abbott Medical Devices

Completed

An Observational, Prospective Evaluation of the Trifecta™ Valve

Aortic Valve Stenosis | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

Germany, Netherlands, France
Maastricht University Medical Center

Unknown

Bicuspid Aortic Valve Stenosis and the Effect of vItamin K2 on Calciummetabolism on 18F-NaF PET/MRI (BASIK2)

Aortic Valve Stenosis | Bicuspid Aortic Valve

Netherlands
Radboud University Medical Center

Recruiting

Colchicine and Inflammation in Aortic Stenosis (CHIANTI)

Cardiovascular Diseases | Inflammation | Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Calcification | Calcification

Netherlands
Maastricht University Medical Center

Completed

Biological Variation of Cardiac Biomarkers in Aortic Valve Stenosis

Aortic Valve Stenosis

Netherlands
MiCardia Corporation

Unknown

Dynamic Annuloplasty System With Activation for the Treatment of Mitral Regurgitation (DYANA)

Mitral Valve Regurgitation

Germany, Netherlands, Canada
Abbott Medical Devices

Completed

Mitral Adjustable Annuloplasty Ring Feasibility and Safety Study (MAARS)

Mitral Valve Regurgitation

Netherlands, Italy, Germany
Romy Hegeman
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Preoperative CT-imaging With Patient-specific Computer Simulation in Transcatheter Aortic Valve Replacement: a Randomized Controlled Trial (GUIDE-TAVI)

Aortic Valve Stenosis

Austria, Netherlands
Medtronic Bakken Research Center

Completed

Medtronic CoreValve REDO Study (REDO)

Aortic Valve Stenosis

Netherlands, Germany
Radboud University Medical Center

Recruiting

Myeloid Cells in Aortic Valve Stenosis (MIRACLE)

Aortic Valve Stenosis | Aortic Valve Disease

Netherlands
Imperial College London
McGill University; Erasmus Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Completed

Protocoled Quantitative Assessment of Aortic Regurgitation Using Videodensitometry in a Multicontinental Trial in Rotterdam, Montreal, Yamaguchi, Segeberg, Amsterdam. (ASSESS-REGURGE)

Aortic Valve Insufficiency | Aortic Valve Regurgitation

Netherlands, Canada, Germany, Japan, United Kingdom
Institut für Pharmakologie und Präventive Medizin

Completed

CGA-TAVI Registry to Evaluate the Predictive Value of a CGA in Predicting TAVI Outcomes (CGA-TAVI)

Aortic Valve Stenosis

Canada, Italy, Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
Edwards Lifesciences

Unknown

Feasibility of Continuous Noninvasive Finger Arterial Blood Pressure Measurement for Detection and Staging of Aortic Stenosis (COaRt)

Aortic Stenosis, Calcific

Netherlands
Cardiawave SA

Completed

Valvosoft First-In-Man Study in Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

France, Netherlands
UMC Utrecht

Completed

Right Ventricle Remodeling After Pulmonary Valve Replacement and Percutaneous Pulmonary Valve Insertion (RV-REPAIR)

Pulmonary Valve Insufficiency | Pulmonary Valve Stenosis | Endomyocardial Fibrosis

Netherlands
UMC Utrecht
Maastricht University Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Recruiting

Dutch-AMR: Early Mitral Valve Repair Versus Watchful Waiting in Asymptomatic Patients With Severe Mitral Regurgitation (Dutch-AMR)

Mitral Regurgitation

Netherlands
Catharina Ziekenhuis Eindhoven

Completed

Pre- and Post TAVI Cognitive Functioning and Intraoperative Carotid Flow Measurements

Cognitive Impairment | Aortic Stenosis, Severe | Older People--Abuse of

Netherlands
Catharina Ziekenhuis Eindhoven
Philips Electronics Nederland BV

Completed

Robustness Check of Placement and Measurement Algorithms for Blood Flow Measurement on Common Carotid Artery (RAdiUS)

Coronary Artery Disease | Aortic Valve Disease | Mitral Valve Disease

Netherlands
Erasmus Medical Center

Recruiting

Coronary Physiology Peri-Transcatheter Left-sided Valvular Interventions (POTUS)

Coronary Artery Disease | Aortic Valve Stenosis | Mitral Regurgitation | Fractional Flow Reserve

Netherlands
Heartcenter, University Medical Center St. Radboud

Completed

A Biomarker and MRI Study on Troponin Release After Exercise in Hypertrophic Cardiomyopathy (BE STRONG HCM)

Hypertrophic Cardiomyopathy

Netherlands
Medtronic Bakken Research Center

Completed

Hancock II Ultra Porcine Bioprosthesis Hemodynamic Study

Aortic Heart Valve Diseases

Belgium, Netherlands, Italy, United Kingdom
Catharina Ziekenhuis Eindhoven

Recruiting

Non-invasive Prediction of Fluid and Noradrenaline Responsiveness Using the Carotid Wave Intensity. (VACC)

Coronary Artery Disease | Shock | Aortic Valve Disease | Mitral Valve Disease

Netherlands
Helios Health Institute GmbH
Abbott

Recruiting

Trifecta and Epic ViV Detailed Insights Into Management Strategies and Outcomes

Aortic Valve Disease

Germany, Belgium, France, Netherlands

Clinical Trials on Heart Valve Replacement in Netherlands

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