Clinical Trials on Heartburn

Total 87 results

Novartis

Completed

Efficacy/Safety of Lansoprazole in Patients With Frequent Nighttime Heartburn

Frequent Heartburn

United States
InQpharm Group

Completed

Safety and Efficacy of IQP-LH-101 in Postprandial Heartburn

Postprandial Heartburn

Germany
Eisai Inc.

Completed

A Study to Investigate Use Patterns and Safety in Simulated Actual Over-the-counter (OTC) Use of Rabeprazole Sodium for the Treatment of Heartburn Symptoms

Frequent Heartburn

United States
Chulalongkorn University

Completed

Alginate-based Reflux Suppressant and Magnesium-aluminium Antacid Gel for Treatment of Heartburn in Pregnancy

Heartburn in Pregnancy

Thailand
MetroHealth Medical Center

Completed

Symptom Control Satisfaction With Proton Pump Inhibitor Regimen

Heartburn

United States
Pfizer

Completed

Pilot Study To Investigate The Association Between Acid Control And Heartburn Symptoms After Proton Pump Inhibitor Treatment

Heartburn

United States
Bayer

Completed

A Study to Compare Omeprazole Administered as Zegerid® Powder and as Prilosec® Capsule in Healthy Participants (P08050)(CL2010-12)

Heartburn
AstraZeneca
Quintiles, Inc.

Completed

To Assess the Efficacy of Esomeprazole 40 mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole

Heartburn

China
Eisai Inc.

Completed

E3810-A001-313: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers

Heartburn

United States
Johnson & Johnson Consumer and Personal Products...

Completed

A Study to Assess the Bioequivalence of Famotidine/Antacid Combination Tablets Compared to Famotidine/Antacid EZ Chew Tablets (0208C-145)(COMPLETED)

Heartburn
AstraZeneca

Completed

Efficacy of Esomeprazole in Patients With Frequent Heartburn (NEXT1)

Heartburn

United States
AstraZeneca

Completed

Acid-Associated Heartburn Symptoms and Dose of Esomeprazole

Heartburn

United States, Puerto Rico
Novartis

Completed

Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn

Heartburn

United States
Eisai Inc.

Completed

E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers

Heartburn

United States
Aboca Spa Societa' Agricola
La Sociedad Española de Médicos de Atención Primaria; Dynamic

Completed

Mipolixin® Compared to Poliprotect® in Moderate Functional Dyspepsia and Heartburn.

Dyspepsia | Heartburn

Spain
Assiut University

Not yet recruiting

Prevalence of Fuctional Heartburn in Patients With IBS .

Heartburn
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Bioequivalence of Famotidine Chewable Tablets and Film-Coated Tablets (0208-144)

Heartburn
AstraZeneca

Completed

Efficacy of Esomeprazole in Patients With Frequent Heartburn (NEXT2)

Heartburn

United States
Novartis

Completed

Proof of Concept Study Efficacy of an Antacid/Lansoprazole Combination for Relief of Heartburn

Heartburn

United States
AstraZeneca

Completed

Esomeprazole And Symptomatic Response In Patients With Or Without An Elevated Risk For Non-Steroidal Anti-Inflammatory Drug (NSAID)-Associated GI Damage (Synchronise)

Heartburn
Novartis

Completed

Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn

Heartburn

United States
University of Southern California

Withdrawn

PPI Versus Placebo in Severe Functional Heartburn

GERD

United States
Novartis

Completed

The Role of Tegaserod Therapy in the Management of Dyspeptic Symptoms in Female Patients on Proton Pump Inhibitors for the Treatment of Heartburn.

Dyspepsia

United States
University of Florida
Lallemand Bio-Ingredients

Completed

Fermented Soy and Heartburn Symptom Relief

Heartburn | Acid Regurgitation

United States
Bayer

Completed

Comparison of Two Omeprazole-Containing Products for Relief of Frequent Heartburn (MK-0764A-036)

Heartburn
University Hospital, Basel, Switzerland

Recruiting

Smartphone App-assisted PPI (PIPPI)

Dyspepsia | Heartburn

Switzerland
Forest Laboratories

Completed

Efficacy and Safety of Itopride vs Placebo in Heartburn

Heartburn

United States
Hawthorne Effect Inc.
HLNatural, Inc.

Completed

Upset Stomach Relief for Mild and Moderate Indigestion and Heartburn

Heartburn | Indigestion

United States
Bayer

Completed

Placebo Controlled Phase IV Study to Compare the Efficacy and Safety of a Single Dose of Oral Talcid, a Single Dose of Oral Famotidine and a Single Dose of Placebo in Patients With Acute Heartburn Episodes

Heartburn

Germany
Microbiome Health Sciences

Completed

Tolerability Study of Panosyl-Isomaltooligosaccharides (PIMO) and a Placebo in Subjects With Heartburn

Heartburn

United States
Seoul National University Bundang Hospital

Completed

Predictors of Proton Pump Inhibitor Response in Gastroesophageal Reflux Disease Patients

Erosive Reflux Disease | Non-erosive Reflux Disease | Functional Heartburn

Korea, Republic of
American University of Beirut Medical Center
Takeda

Completed

An Open-Label Trial of Dexlansoprazole 60mg for the Relief of Heartburn During the Fasting Month of Ramadan

GERD | Proton Pump Inhibitor

Lebanon
Novartis

Completed

The Effects of Tegaserod on Mechanical Sensitivity of the Esophagus and Stomach in Patients With Heartburn and Dyspepsia.

Dyspepsia | Heartburn

United States
Universitaire Ziekenhuizen KU Leuven

Recruiting

Primary carE PPi dEprescRibing Trial (PEPPER)

Dyspepsia | Heartburn | Reflux

Belgium
Universitaire Ziekenhuizen KU Leuven

Unknown

Citalopram for Reflux Hypersensitivity and Functional Heartburn

GERD

Belgium
Assaf-Harofeh Medical Center

Unknown

A Comparison of Factors of Symptoms Generation and Evaluation of Role of Biofeedback in Patients With Different Types of Functional Esophageal Disorders (Functional Heartburn and Functional Chest Pain)

Chest Pain | Heartburn
Bayer

Recruiting

A First-in-Human Study to Learn How Well a Bi-Layer Calcium Carbonate Antacid Tablet Works Compared to a Standard, Non-Layered Calcium Carbonate Tablet in Healthy Male Participants

Healthy Volunteers | Heartburn | Indigestion | Stomach Acid Related Symptoms | Nocturnal Stomach Acid Related Symptoms

United Kingdom
AstraZeneca

Completed

A Randomized, Open-Label, Comparative 3-Way Treatment Crossover Study of 24-Hour Intragastric pH Profile of Once Daily Oral Administration of Esomeprazole 40mg, Lansoprazole 30mg, and Pantoprazole 40mg at Steady State in NSAID-Using Patients

Nausea | Heartburn | Acid Regurgitation | Upper Abdominal Pain
Seoul National University Bundang Hospital

Completed

Analysis of GERD Symptoms Using Gastroesophageal Reflux Impact Score Questionnaire for Quality of Life

Non-erosive Reflux Disease (NERD) | Reflux Esophagitis (RE) | Functional Heartburn (FH)

Korea, Republic of
Medical Research Council
King's College London

Completed

Questionnaire to Assess Gastrointestinal Symptoms of Oral Iron.

Abdominal Pain | Constipation | Diarrhea | Anemia | Heartburn | Side Effect

United Kingdom
Heidelberg University

Completed

Esomeprazole and Gastric Emptying of Beer

Gastroesophageal Reflux | Heartburn

Germany
Janssen-Ortho Inc., Canada

Completed

Open Label Study Evaluating Different Dosing Regimens of Rabeprazole in Gastro-esophageal Reflux Disease (GERD) Patients With Night-time Heartburn Symptoms.

Gastroesophageal Reflux | Heartburn
Universidad Miguel Hernandez de Elche

Not yet recruiting

Protocol for the ESREFLUJO Study: Epidemiological Study of Heartburn and Gastroesophageal Reflux in Community Pharmacy (ES-REFLUJO)

Reflux
Helsinki University Central Hospital

Unknown

Efficacy Study of Articaine Lozenge to Enhance the Procedural Compliance of the Adults Undergoing Gastroduodenoscopy

Dyspepsia | Abdominal Pain | Heartburn | Hematemesis

Finland
Janssen Pharmaceutica N.V., Belgium

Completed

A Study of Efficacy and Safety of "On-demand" Maintenance Therapy With Rabeprazole in Patients With Non-erosive Reflux Disease (NERD)

Gastroesophageal Reflux | Heartburn
Mayo Clinic

Recruiting

A Study of Breath Testing for Small Intestinal Bacterial Overgrowth

Gastroesophageal Reflux | Heartburn | Regurgitation

United States
AstraZeneca

Completed

HEARD (Long Term) Study - Histology of the Esophagus in Acid-Related Disease

Dyspepsia | Gastroesophageal Reflux | Heartburn

Canada
University of North Carolina, Chapel Hill

Completed

Do Acid Sensing Ion Channels Contribute to Heartburn?

Gastroesophageal Reflux Disease | Heartburn

United States
Chang Gung Memorial Hospital

Completed

Efficacy and Safety of Sodium Alginate Oral Suspension to Treat Non-erosive Gastro-esophageal Reflux Disease

Gastroesophageal Reflux Disease | Heartburn

Taiwan
AstraZeneca

Completed

Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease | Heartburn

3

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