Clinical Trials on Helminthiases

Total 331 results

Baylor College of Medicine
Johns Hopkins University; University of California, San Francisco; George Washington... and other collaborators

Completed

Study of Na-APR-1 (M74)/Alhydrogel® Co-administered With Na-GST-1/Alhydrogel in Brazilian Adults

Hookworm Infection | Hookworm Disease

Brazil
Baylor College of Medicine

Completed

Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children

Hookworm Infection | Hookworm Disease

Gabon
National Institute of Allergy and Infectious Diseases...

Completed

The Effect of Parasitic Worm Infections on the Immune Response to Tuberculosis Bacteria

Filarial Infection | Intestinal Helminth Infection

India
First Affiliated Hospital of Zhejiang University

Completed

Synbiotics Interventions for Managing Cirrhosis and Its Complications

Cirrhosis, Liver | Metagonimiasis

China
Medical Park Gaziantep Hospital

Completed

Laparoscopic Versus Open Surgery for the Management of Cystic Echinococcosis of the Liver

Echinococcosis, Hepatic | Hydatid Cyst

Turkey
DBL -Institute for Health Research and Development

Completed

Evaluation of the Use of a Urin Test Strip to Determine the Spread of Schistosoma Infections in Areas Where Schistosomiasis Infections Are Low in Kenya

Schistosomiasis Mansoni | Circulating Cathodic Antigen Urine Based Dipstick

Kenya
Abdullah Adiyaman

Recruiting

The Importance of Inflammatory Markers Calculated From Preoperative and Postoperative Peripheral Blood Results in the Diagnosis and Treatment of Patients Operated for Hydatid Cyst of the Lung (Lung Echinococcus Granulosus) (Echinococcusis)

Lung Hydatid Cyst

Turkey
Yarmouk University

Completed

Spleen Preserving Surgery for Splenic Hydatidosis: A Cohort Study on Short and Long-Term Outcomes

Minimally Invasive Surgery | Hydatid Disease | Spleen-Preserving Surgery | Echinococcus Granulosus Infection

Jordan
Centre de Recherche Médicale de Lambaréné
University Hospital Tuebingen; Technical University of Munich

Completed

Helminth Infection During Pregnancy on Vitamin D Regulation: HELMVIT Study (HELMVIT)

Vitamin D Deficiency | Immunosuppression

Gabon
Swiss Tropical & Public Health Institute
Drugs for Neglected Diseases; Ifakara Health Institute

Completed

PK, Safety and Tolerability of Single and Multiple Doses of Oxfendazole Tablets (HELP-OFZ)

Filariasis

Tanzania
Albert B. Sabin Vaccine Institute

Completed

Development of a Skin Test for the Na-ASP-2 Hookworm Antigen

Allergy | Hookworm Infection

United States
University Ghent
University of Nottingham; George Washington University; World Health Organization and other collaborators

Completed

A Multinational Trial of the Efficacy of Albendazole Against Soil-transmitted Nematode Infections in Children (WORMCON)

Infections With Soil-Transmitted Helminths (STH)

Cambodia, Vietnam, Brazil, Cameroon, Ethiopia, India, Tanzania
Programme National de Lutte contre l'Onchocercose...
Institut de Recherche pour le Developpement

Not yet recruiting

A 3- to 5-day Clinical Trial of Levamisole in Loiasis Infected Subjects (STOP-FiLAR)

Loiasis
Albert Einstein College of Medicine

Terminated

Treatment of Strongyloides Infection (TSSI)

Strongyloidiasis | Strongyloides Stercoralis Infection

United States
DBL -Institute for Health Research and Development
Ministry of Health, Uganda

Completed

The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda

Malaria | Schistosomiasis

Uganda
IRCCS Sacro Cuore Don Calabria di Negrar

Not yet recruiting

Preliminary Evaluation of Two Rapid Diagnostic Test Prototypes for Strongyloides Stercoralis Infection (PROTOSS)

Strongyloides Stercoralis Infection

Italy
University Hospital, Angers

Not yet recruiting

Assessment and Treatment of Loiasis With Positive Microfilaremia (LoPoMi)

Loiasis With Positive Blood Microfilaremia
National Institute of Allergy and Infectious Diseases...

Completed

Reslizumab to Prevent Post-treatment Eosinophilia in Loiasis

Loiasis

United States
Jennifer Keiser
Centre Suisse de Recherches Scientifiques en Cote d'Ivoire

Completed

Albendazole Dose Finding and Pharmacokinetics in Children and Adults

Hookworm Infections | Trichuriasis

Côte D'Ivoire
Bird, Christopher
London School of Hygiene and Tropical Medicine; Fondazione Ivo de Carneri,...

Completed

Study to Test Whether Shoes Protect Children Against Hookworm Infection on Pemba Island, Zanzibar (SKIP)

Hookworm

Tanzania
PATH
Yale University; Ghana Health Services; Kintampo Health Research Centre, Ghana; Noguchi Memorial Institute for Medical Research and other collaborators

Withdrawn

Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana

Hookworm Infections

Ghana
Janssen-Cilag Ltd.

Completed

Study to Evaluate Efficacy and Safety of a Double Treatment Plan Using a Combination of Mebendazole and Quinfamide for Treating Intestinal Helminthiasis and Amebiasis in the Mexican Population

Helminthiasis | Amoebiasis

Mexico
National Institute of Allergy and Infectious Diseases...

Completed

Research for Elim of Filariasis

W. Bancrofti Filariasis

Egypt
George Washington University
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Controlled Human Infection Study of Orally Administered Trichuris Trichiura Eggs in Naïve Adults

Trichuriasis | Whipworm | Controlled Human Infection

United States
Baylor College of Medicine

Recruiting

Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae

Hookworm Infection

United States
Swiss Tropical & Public Health Institute

Completed

Triple Combinations Against Hookworm Infections in Lao (Tricombi)

Hookworm Infection

Lao People's Democratic Republic
Baylor College of Medicine
Bill and Melinda Gates Foundation

Completed

Study of Na-ASP-2 Human Hookworm Vaccine in Healthy Adults Without Evidence of Hookworm Infection

Hookworm Infection

United States
Navrongo Health Research Centre, Ghana
DBL -Institute for Health Research and Development

Unknown

Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren in Kassena-Nankana, Ghana (ACTIPT)

Anemia | Malaria | Helminthiasis | Schistosomiasis | Change in Sustained Attention

Ghana
University of Washington
Centers for Disease Control and Prevention; Kenya Medical Research Institute

Completed

Empiric Therapy of Helminth Co-infection to Reduce HIV-1 Disease Progression (THE or PHE)

HIV Infections | Helminthiasis

Kenya
McMaster University
Canadian Institutes of Health Research (CIHR); Khon Kaen University; Global Alliance...

Not yet recruiting

Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, Thailand (eCHEC)

Cholangiocarcinoma | Liver Fluke-Related Cholangiocarcinoma | Opisthorchiasis

Thailand
University Hospitals Cleveland Medical Center
Washington University School of Medicine

Completed

Pharmacokinetics & Pharmacodynamics of Diethylcarbamazine (DEC)+ Albendazole (ALB) + Ivermectin (IVE)

Wuchereria Bancrofti Infection

Côte D'Ivoire
Salmon, Margaret, M.D.
Bill and Melinda Gates Foundation; Akeso Associates; Eastern Congo Initiative; HEAL...

Unknown

Does Treating Hookworm Improve Productivity of Small Subsistence Farmers

Anemia | Exercise Tolerance | Hookworm Stool Burden

Congo
Assiut University

Not yet recruiting

Parasitism & COVID19 Vaccines: New Challenge.

Protozoan Infections | Helminths Infection
Oxfendazole Development Group
Universidad Peruana Cayetano Heredia, Lima, Peru

Not yet recruiting

Efficacy of Oxfendazole in the Treatment of Trichuris Trichiura Infection in Adults

Trichuris Infection
Jennifer Keiser
Centre Suisse de Recherches Scientifiques en Cote d'Ivoire

Completed

Efficacy and Safety of MOX/ALB Co-administration

Hookworm Infections | Ascariasis | Trichuriasis

Côte D'Ivoire
Universidad de Extremadura

Completed

Surgical Treatment of Hepatic Hydatidosis in Elderly Patients (ELDHIDA)

Cystic Echinococcosis

Spain
University Ghent
VLIR-UOS Institutional University Cooperation

Completed

The Efficacy of Five Anthelmintic Regimes Against Trichuris Trichiura Infections in Schoolchildren in Jimma, Ethiopia

Infection by Trichuris Trichiura

Ethiopia
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Not yet recruiting

Efficacy, Safety and Acceptability of Ivermectin ODT in PSAC (Iverped)

Hookworm Infections | Ascariasis | Trichuriasis

Tanzania
Shiraz University of Medical Sciences

Completed

The Current Study Aimed to Evaluate the Therapeutic Features and Complications of Liver Hydatid Cyst in Patients Who Underwent Surgery for CE in Fars Province, Southern Iran.

Patients Who Underwent Surgury for Hydatid Cyst

Iran, Islamic Republic of
IRCCS Sacro Cuore Don Calabria di Negrar

Recruiting

Filling Key Research Gaps With Clinical Implications in Mansonellosis and Schistosomiasis: a Network Approach

Schistosoma Mansoni

Italy
National Institute of Allergy and Infectious Diseases...

Recruiting

Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia

Immune System Diseases | Hypersensitivity | Eosinophilia | Helminthiasis | Parasitic Disease

United States
Leiden University Medical Center

Completed

Establishing a Controlled Human Hookworm Infection Model at Leiden University Medical Center (CHHIL)

Necator Americanus Infection

Netherlands
Meta Roestenberg

Completed

Repeated Controlled Human Hookworm Infection (ReCHHI1)

Necator Americanus Infection

Netherlands
University of Toronto
UVRI-IAVI HIV Vaccine Program, Uganda

Completed

Effect of Schistosomiasis Mansoni on HIV Susceptibility and Female Genital Immunology

HIV | Schistosomiasis Mansoni

Uganda
London School of Hygiene and Tropical Medicine
Emory University; Bill and Melinda Gates Foundation; KIIT University, Bhubaneswar... and other collaborators

Unknown

Assessing the Health Impact of a Combined Water and Sanitation Intervention in Rural Odisha, India

Diarrhea | Stunting | Soil-transmitted Helminth Infection | Enteric Infection

United Kingdom
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Not yet recruiting

Efficacy and Safety of MOX/ALB Co-administration in SAC (Moxiped)

Hookworm Infections | Ascariasis | Trichuriasis

Tanzania
Washington University School of Medicine
Case Western Reserve University; Regional Hospital of Agboville, Southern Cote...

Active, not recruiting

Moxidectin for LF, Cote d'Ivoire (DOLF)

Lymphatic Filariasis

Côte D'Ivoire
University Hospitals Cleveland Medical Center
Washington University School of Medicine

Completed

Lymphatic Filariasis (LF) in Ivory Coast

Lymphatic Filariasis

Côte D'Ivoire
Baylor College of Medicine
George Washington University

Completed

Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy Adults

Hookworm Infection | Hookworm Disease

United States
Baylor College of Medicine

Completed

Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults

Hookworm Infection | Hookworm Disease

Gabon

Clinical Trials on Helminthiases

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cote d'Ivoire

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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