Clinical Trials on Hematologic Disorders

Total 149073 results

Accenture

Completed

Repeat Dose Safety Study for Compound to Treat Hematologic Cancer

Hematologic Malignancies

Korea, Republic of, Australia, Canada
National Cancer Institute (NCI)

Recruiting

Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid Malignancies

Lymphoma | Non-Hodgkin Lymphoma | NHL | Hematologic Malignancies | Lymphoid Malignancies

United States
Hospital Clinic of Barcelona

Unknown

Thromboelastometry in Liver Transplantation

Liver Transplant Disorder | Coagulopathy

Spain
Stanford University

Enrolling by invitation

Gastrointestinal STRING Test With Oral Immunotherapy (STRING)

Food Allergy | Eosinophilic Disorder

United States
Ospedale Santa Croce-Carle Cuneo

Unknown

Invasive Aspergillosis After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Invasive Aspergillosis | Hematological Diseases

Italy
Fenwal, Inc.

Completed

Evaluation of Therapeutic Plasma Exchange (TPE) Procedure Using the AMICUS Device

Autoimmune Diseases | Oncologic Disorders | Renal Disorders | Hematologic Disorders

United States
Novo Nordisk A/S

Completed

Safety, Tolerability and Pharmacokinetics of NN1731 in Healthy Volunteers

Healthy | Congenital Bleeding Disorder

Japan
Medical University of Graz
Joanneum Research Forschungsgesellschaft mbH

Completed

Bioequivalence of Topical Acyclovir in Healthy Volunteers (FDA_BE1)

Dermatologic Disorders

Austria
Istanbul Aydın University

Recruiting

The Effect of Lavender Oil on Fatigue and Sleep Quality

Patient Participation | Hematologic Malignancies

Turkey
Deborah Rund

Completed

Analysis of Genetic Factors Related to Predisposition and Prognosis of Hematological Malignancies in Israel

Acute Myeloid Leukemia | Chronic Lymphocytic Leukemia | Chronic Myelogenous Leukemia

Israel
St. Jude Children's Research Hospital
Teva Pharmaceuticals USA

Completed

Bendamustine Hydrochloride, Clofarabine, and Etoposide in Treating Younger Patients With Relapsed or Refractory Hematologic Malignancies

Hodgkin Lymphoma | Non-Hodgkin Lymphoma | Acute Leukemia

United States
Rigshospitalet, Denmark

Active, not recruiting

Sexual Health in Patients With Hematologic Malignancies

Quality of Life | Sexual Dysfunction | Sexuality | Psychological | Symptoms and Signs

Denmark
Gazi University

Completed

Exercise Capacity and Physical Activity Levels in Newly Diagnosed Hematologic Malignant Patients

Hematologic Malignancies

Turkey
University Malaysia Sarawak
University of Malaya

Completed

Single Session of 30-Minute Mindful Breathing in Reducing Fatigue

Fatigue | Hematologic Malignancy

Malaysia
UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics (DISCOVERY)

Lymphoma | Leukemia | Multiple Myeloma | Hematologic Malignancies | Blood Cancers

United States
Millennium Pharmaceuticals, Inc.

Completed

Study of MLN4924, a Novel Inhibitor of Nedd8 Activating Enzyme, in Adult Patients With Lymphoma or Multiple Myeloma

Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Hematologic Malignancies

United States
Medical College of Wisconsin

Terminated

Nivolumab and Tocilizumab for Relapsed Hematological Malignancy Post-allogeneic Transplant

Lymphoma | Myelodysplastic Syndromes | Acute Leukemia | Chronic Leukemia

United States
American Thrombosis and Hemostasis Network
Sanofi; Pfizer; Genentech, Inc.; CSL Behring; Hemophilia of Georgia, Inc.; Hemab Therapeutics

Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

Hemophilia | Thrombosis | Thrombophilia | Sickle Cell Disease | Thalassemia | Bleeding Disorder | Von Willebrand Diseases | Factor IX Deficiency | Connective Tissue Disorder | Factor VIII Deficiency | Hematologic Disorder | Rare Bleeding Disorder | Platelet Disorder

United States
Kristian Karstoft

Active, not recruiting

The Effect of Exercise on Pharmacodynamics and Pharmacokinetics of a Single Dose of Unfractionated Heparin

Blood Coagulation Disorder

Denmark
Amgen

Terminated

Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 397 in Subjects With Selected Relapsed or Refractory Hematological Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | AML | Myelodysplastic Syndrome | MDS | Non-Hodgkins Lymphoma | NHL

United States, Australia, Italy, France, Greece, Japan
Michael A. Thompson, MD, PhD
Vince Lombardi Cancer Clinic

Withdrawn

B-Cell Hematologic Malignancy Vaccination Registry (HMvax-Regist)

Lymphoma, Non-Hodgkin | Multiple Myeloma | Waldenstrom Macroglobulinemia | Monoclonal Gammopathy of Undetermined Significance | Hematological Malignancies | B-Cell Chronic Lymphocytic Leukemia | Lymphocytosis

United States
National Cancer Institute (NCI)

Suspended

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

Lymphoma | Leukemia

United States
University of Miami

Completed

INR Comparison Testing in Cardiac Surgery

Coagulation Disorder

United States
University College Cork
Cancer Research@UCC

Recruiting

Discontinuation Study

Cancer | Multiple Myeloma | Hematologic Cancer

Ireland
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Screening for Hematology Branch Protocols

Healthy Volunteer | Hematologic Disease and Disorders | Donors

United States
Amgen

Terminated

Open-label Study of the Safety and Activity of Oprozomib in Patients With Hematologic Malignancies

Multiple Myeloma | Waldenstrom Macroglobulinemia

United States
Neena Kapoor, M.D.

Not yet recruiting

TCRαβ/CD19 Depletion of Stem Cell Grafts for Transplant

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Hematologic Malignancy | Graft Vs Host Disease | Graft-versus-host-disease | Non-hematologic Malignancy
Novo Nordisk A/S

Completed

Use of Activated Recombinant FVII in Spinal Surgery

Spinal Fusion | Acquired Bleeding Disorder

United States
Novo Nordisk A/S

Completed

Observational Study on Safety and Efficacy of NovoSeven® in Subjects With Congenital FVII Deficiency

Congenital Bleeding Disorder | Congenital FVII Deficiency

Japan
Maastricht University Medical Center

Unknown

Management and Outcomes of Anti-thrombotic Medication Use in Thrombocytopenia (MATTER)

Hematologic Neoplasms | Thrombocytopenia | Anticoagulants | Platelet Aggregation Inhibitors

Netherlands, Italy, Israel, United States
Weprom
L'effet Papillon

Completed

Therapeutic Virtual Reality : Impact on the Management of Pain and Anxiety Related to Hematology Care (REVEH) (REVEH)

Hematologic Neoplasms

France
Pfizer
Medivation, Inc.

Completed

Study of BMN 673, a PARP Inhibitor, in Patients With Advanced Hematological Malignancies

Acute Myeloid Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome

United Kingdom, United States
Memorial Sloan Kettering Cancer Center
Sanofi

Recruiting

Open-Label, Phase II Trial of Isatuximab for Patients With Refractory Immune Cytopenias After Allogeneic Hematopoietic Cell Transplantation

Blood Cancer | Refractory Immune Cytopenias

United States
Sir Run Run Shaw Hospital

Recruiting

Carbapenem-resistant Organisms (CRO) Screening From Rectal Swabs in Patients With Hematological Diseases in China (CROSS)

Hematological Diseases | Carbapenem-resistant Enterobacteriaceae | Carbapenem-resistant Pseudomonas Aeruginosa | Carbapenem-resistant Acinetobacter Baumannii

China
Novo Nordisk A/S

Completed

Safety of a Single Intravenous Dose of Recombinant Factor XIII in Children With Congenital FXIII A-subunit Deficiency (mentor™4)

Congenital Bleeding Disorder | Congenital FXIII Deficiency

United States, Israel, United Kingdom
Memorial Sloan Kettering Cancer Center

Active, not recruiting

T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia

Myeloid Diseases

United States
Gamida Cell ltd

Completed

Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM

Hematological Malignancies | Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS)

United States, Singapore, Spain, Netherlands, Italy
University Hospital, Geneva

Completed

Standardisation of Investigations of Mild Bleeding Disorders (MBD)

Hemorrhagic Disorders

Switzerland
Centre Hospitalier Universitaire de Nīmes

Recruiting

Is There an Association Between Innate CD8+ T Cells and the Evolution of Tyrosine Kinase Inhibitor Resistance Mutations in Phi+ Hematological Malignancies. (TIPHI)

Leukemia | Chronic Leukemia | Myelogenous Leukemia | BCR-ABL Positive Acute Myeloid Leukemia

France
The Cleveland Clinic

Not yet recruiting

Quantra Point-of-Care Hemostasis Monitoring (QUANTRA)

Bleeding | Hemostatic Disorder
Blueprint Medicines Corporation
Analysis Group, Inc.

Completed

Retrospective Study Assessing the Effect of Avapritinib Versus Best Available Therapy in Patients With AdvSM

Mast Cell Leukemia | Aggressive Systemic Mastocytosis | Advanced Systemic Mastocytosis | Systemic Mastocytosis With an Associated Hematological Neoplasm

United States, Austria, Germany, Spain, United Kingdom
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety and Tolerance of SYHX1903 in Patients With Relapsed/Refractory Hematologic Malignancies

Lymphoma | Acute Myeloid Leukemia | Multiple Myeloma
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Weill Medical...

Completed

Screening for Colonization With Resistant Enterobacterales in Neutropenic Patients With Hematologic Malignancies (SCENE)

Neutropenia | Hematologic Malignancy | Bloodstream Infection | Leukemia, Acute

United States
Novo Nordisk A/S

Enrolling by invitation

A Study of Safety and Effectiveness of NovoThirteen® (rFXIII) During Treatment of Congenital FXIII Deficiency in Japan

Congenital Bleeding Disorder | Congenital FXIII Deficiency

Japan
Novo Nordisk A/S

Completed

Use of rFXIII in Treatment of Congenital FXIII Deficiency, a Prospective Multi-centre Observational Study (mentor™6)

Congenital Bleeding Disorder | Congenital FXIII Deficiency

Spain, United States, Canada, Italy, United Kingdom, Hungary
Novo Nordisk A/S

Completed

Safety and Efficacy of Monthly Replacement Therapy With Recombinant Factor XIII (rFXIII) in Paediatric Subjects With Congenital Factor XIII A-subunit Deficiency (mentor™5)

Congenital Bleeding Disorder | Congenital FXIII Deficiency

United Kingdom, Israel, United States
AstraZeneca

Terminated

A Study of AZD0466 in Patients With Advanced Hematologic or Solid Tumors

Lymphoma | Multiple Myeloma | Advanced Solid Tumors | Hematologic Malignancies

United States
Jens Rikardt Andersen

Completed

Randomized Trial:the Effect of Liquid Food on the Intake of Energy and Protein in Malignant Hematologic Patients

Delayed Gastric Emptying | Hematological Disease | Malignant Disease

Denmark
Novo Nordisk A/S

Completed

Safety and Pharmacokinetics of Recombinant Factor XIII in Healthy Volunteers

Healthy | Congenital Bleeding Disorder | Congenital FXIII Deficiency

United Kingdom
Novo Nordisk A/S

Completed

Safety and Pharmacokinetics of Recombinant Factor XIII Administration in Healthy Volunteers

Healthy | Congenital Bleeding Disorder | Congenital FXIII Deficiency

United Kingdom

Clinical Trials on Hematologic Disorders

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