Clinical Trials on MPA

Total 291 results

Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Assess the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Mycophenolate Mofetil in Healthy Adult Subjects

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Plasma Mycophenolic Acid (MPA) | Pharmacokinetics of Plasma Phenolic Glucuronide of MPA (MPAG)

United States
Danish Headache Center

Completed

The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.

Headache | Dilatation of Cranial Arteries; MMA, STA and MCA

Denmark
Brigham and Women's Hospital

Completed

Establishing 18F-PBR06 PET Imaging as a Viable Pharmacodynamic Endpoint in MSA

MSA

United States
Rennes University Hospital

Completed

Identification of Difficulties During a First Request for a Personal Autonomy Allowance (IDAPA)

Persons Requesting a Resource Allocation (APA) | Beneficiairies Requesting a Resource Allocation (APA)

France
InflaRx GmbH

Completed

Study of IFX-1 to Replace Steroids in Patients With Granulomatosis With Polyangiitis and Microscopic Polyangiitis. (IXchange)

Granulomatosis With Polyangiitis (GPA) | Microscopic Polyangiitis (MPA)

Germany, Russian Federation, Belgium, France, Spain, Czechia, Italy, Netherlands, Sweden, Switzerland, United Kingdom
Erasme University Hospital
University of California, Los Angeles; University of California, Irvine

Completed

Closed-loop Control of Vasopressor Administration in Cardiac Surgery

Hemodynamic MAP Stability

Belgium
InflaRx GmbH
Iqvia Pty Ltd

Terminated

Safety and Efficacy Study of IFX-1 in add-on to Standard of Care in GPA and MPA

Granulomatosis With Polyangiitis (GPA) | Microscopic Polyangiitis (MPA)

United States, Canada
Milton S. Hershey Medical Center
BioSensics

Recruiting

Digital Tools for Assessment of Motor Functions and Falls in ALS

ALS | PLS | PMA

United States
Erasme University Hospital
University of California, Los Angeles; University of California, Irvine

Completed

Closed-loop Vasopressor Infusion Using Continuous Noninvasive Blood Pressure Monitoring

Hemodynamic (MAP) Stability

Belgium
University of Pennsylvania
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Plasma Exchange and Glucocorticoids for Treatment of Anti-Neutrophil Cytoplasm Antibody (ANCA) - Associated Vasculitis (PEXIVAS)

Microscopic Polyangiitis (MPA) | Granulomatosis With Polyangiitis (Wegener's) (GPA)

United States, Belgium, France, United Kingdom, Denmark, Canada, Japan, Australia, New Zealand, Sweden, Czechia, Italy, Greece, Mexico, Norway
Shalvata Mental Health Center

Completed

A Study on the Effect of Methylphenidate on Creativity of Healthy Adults

MPH Influence on Creativity
Assiut University

Completed

Depot-medroxy Progesterone Acetate Injectable Contraceptives in Lactating Women 1st Week Versus 6 Week Postpartum Initiation

Complications of DMPA Injectable Contraceptives

Egypt
Chang Gung Memorial Hospital

Completed

Single-scan Rest/Stress Imaging With Cadmium Zinc Telluride-based SPECT for Coronary Flow Quantification

Quantitative Analysis of SPECT MPI
PAULO VINICIUS SOARES

Unknown

Influence of Temporary Filling Material Composition on the Success Rate of Endodontic Treatments

MTA | Calcium Hydroxide | Endodontic Treatment

Brazil
Zimmer Biomet

Completed

Metal-on-metal Hip Replacement MRI Study

Hip Athroplasty Using M2a Magnum

United Kingdom
National Taiwan University Hospital

Unknown

Long-term Efficacy of Carglumic Acid in Organic Acidemia.

Propionic Acidemia (PA) , Methylmalonic Acidemia (MMA)

Taiwan
Kirsehir Ahi Evran Universitesi

Completed

Mitochondrial Membrane Protein Neurodegeneration (MPAN)

MPAN

Turkey
University of Michigan
National Institute on Minority Health and Health Disparities (NIMHD)

Not yet recruiting

Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness

PTSD | Stress | Trauma | HPA
Sigilon Therapeutics, Inc.

Withdrawn

Safety and Efficacy of Encapsulated Allogeneic MPS-1 Therapy

MPS I | MPS1-S | MPS1-HS

Brazil, United Kingdom
University of California, Berkeley
Tigray Regional Health Bureau; Venture Strategies for Health and Development; Venture Strategies innovations

Completed

Community Based Distribution of Injectable Contraceptives in Tigray, Ethiopia (CBDDMPA)

Contraception | Family Planning | Task Shifting | Community Based Distribution | DMPA

Ethiopia
Federal University of Uberlandia

Unknown

Influence of the Composition of Temporary Restorative Material in Vital Teeth

MTA | Dental Restoration, Temporary

Brazil
Federal University of Uberlandia

Unknown

Influences of Different Temporary Cement on Retention Rate of Temporary Crowns

MTA | Calcium Hydroxide | Dental Crown

Brazil
University of Debrecen

Unknown

Middle Cerebral Artery Velocity and Oxygen Saturation of the Brain During Carotid Endarterectomy

Cerebral Oxygen Saturation,MCA Velocity,Intraoperative Neurological Symptoms During Carotid Endarterectomy

Hungary
Pope Research Corporation
Abbott; Academic Medical Organization of Southwestern Ontario

Completed

Closing the Gap in Care in Seronegative Inflammatory Arthritis (Metrix II)

SpA | PsA

Canada
Michael Savona
Incyte Corporation; Astex Pharmaceuticals, Inc.; Theradex

Recruiting

Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes Overlap Syndromes (ABNL-MARRO) (ABNL-MARRO)

MDS/MPN

United States
Biotheus Inc.

Recruiting

A Study of PM8002 Injection in Combination With Standard Chemotherapy as First Line Therapy in MPM

MPM

China
Hadassah Medical Organization

Completed

Comparison of MedCem MTA and Formocresol Used in Pulpotomies in Primary Teeth.

Pulpotomies Primary Teeth | Effectiveness of MedCem MTA® in Pulpotomies Primary Teeth

Israel
New York State Psychiatric Institute
National Institute of Mental Health (NIMH)

Not yet recruiting

Impacts of Cash Transfers on Child Neurodevelopment (Auxilio Brasil)

Inflammation | Family Relations | HPA | CBCL

United States, Brazil
Universitat Internacional de Catalunya

Unknown

MEDCEM PC and MTA in Pulpotomies of Primary Molars

Evaluate the Effects of MEDCEM PC and MTA in Pulpotomies of Primary Molars.

Spain
University of California, San Francisco
Duke University

Recruiting

In Utero Enzyme Replacement Therapy for Lysosomal Storage Diseases (IUERT)

Wolman Disease | MPS IVA | Pompe Disease Infantile-Onset | Gaucher Disease, Type 2 | MPS VI | MPS I | Gaucher Disease, Type 3 | MPS II | Mps VII

United States
The First Affiliated Hospital with Nanjing Medical...
Jiangbin Hospital Affiliated to Jiangsu University; Nanjing Second Hospital; Jiangning...

Recruiting

Clinical Study of Azacitidine Combined With Ruxolitinib in the Treatment of Higher-risk MDS/MPN

MDS/MPN

China
Mayo Clinic

Enrolling by invitation

Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders (AND1)

Parkinson Disease | Semantic Dementia | Behavioral Variant of Frontotemporal Dementia | CBD | Apraxia of Speech | MSA - Multiple System Atrophy | FTD | PPA | PSP | PCA | LPA | Semantic Aphasia

United States
Thomas Cherpes, DVM, MD
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Modulation of Mucosal and Systemic Immunity by Hormonal Contraceptives

Initiation of Oral Contraception (OC) | Initiation of Depo-Provera (DMPA) | Initiation of Mirena (LNG-IUD)

United States
National Cancer Institute (NCI)

Withdrawn

Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin

Malignant Pleural Mesotheliomas (Mpm) | Malignant Pleural Effusions (Mpe) | Epithelial Tumors, Malignant | Pleural Effusions, Malignant | Mesothelin (Msln)

United States
Assistance Publique - Hôpitaux de Paris
French Vasculitis Study Group

Active, not recruiting

Efficacy and Safety of Rituximab in the Treatment of Good Prognosis Microscopic Polyangiitis (RITUXGOPRO)

Microscopic Polyangiitis (MPA)

France
University of Leipzig
Deutsche Krebshilfe e.V., Bonn (Germany)

Recruiting

Study Investigating Patient-Reported Outcomes in Lower-risk MDS Patients (PRO-RED)

MDS | MDS/MPN

Germany, Austria
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Completed

Prevalence of HPV Transmission During Medically Assisted Procreation Procedures (AMPAMAVIR)

Infertility | Human Papillomavirus (HPV) | Medically Assisted Procreation (MAP)

France
Universitätsklinikum Hamburg-Eppendorf

Completed

Diagnosis of Invasive Pulmonary Aspergillosis (IPA) in Critically Ill Patients (DipA)

Survival After IPA | Risk Factors for IPA

Germany
Assiut University

Unknown

Platelet Indices in Decompensated Post Hepatitic Liver Cirrhosis

MPV | PDW
Children's Hospital of Eastern Ontario

Completed

Ultrasound Findings of Finger, Wrist and Knee Joints in Mucopolysaccharidosis

MPS I | MPS IV

Canada
University of California, San Francisco

Recruiting

Safety and Efficacy of Voxzogo for Growth Deficits in MPS IVA and VI

MPS IVA | MPS VI

United States
University of Pennsylvania
University of South Florida; University of Oxford

Completed

The ANCA Vasculitis Questionnaire (AAV-PRO©) (AAV-PRO)

Vasculitis | Churg-Strauss Syndrome (CSS) | Microscopic Polyangiitis (MPA) | Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) (EGPA) | Granulomatosis With Polyangiitis (Wegener's) (GPA) | Wegener Granulomatosis (WG) | ANCA-Associated Vasculitis (AAV)

United States
Hospital de Clinicas de Porto Alegre
The Isaac Foundation

Active, not recruiting

Evaluation of Losartan on Cardiovascular Disease in Patients With Mucopolysaccharidoses IV A and VI

Mucopolysaccharidoses | Mucopolysaccharidosis VI | Morquio A Syndrome | Mucopolysaccharidosis IV A | MPS IV A | MPS VI | MPS - Mucopolysaccharidosis | Morquio Syndrome A | Morquio Syndrome

Brazil
Shire

Completed

Safety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA Patients

Mucopolysaccharidosis (MPS)

United Kingdom, Netherlands
Stanford University

Terminated

Investigation of Dysregulated Signaling in MPD Via Multiparameter Phospho-specific Flow Cytometry

Myeloproliferative Disorders | Myeloproliferative Disorders (MPD)

United States
Federal University of Uberlandia

Unknown

Influence of Resin Cement Composition on the Longevity of Intraradicular Post of Endodontically Treated Teeth

Endodontically Treated Teeth | MTA | Resin Cement

Brazil
Ultragenyx Pharmaceutical Inc
PRA Health Sciences

Recruiting

Mucopolysaccharidosis VII Disease Monitoring Program

Sly Syndrome | Mucopolysaccharidosis VII | MPS VII | MPS 7

United States, Germany, Brazil, Argentina, France, Netherlands, Portugal, Spain, Turkey
Samus Therapeutics, Inc.

Withdrawn

A Study of Zelavespib (PU-H71) in Subjects With AP-MPN or BP-MPN (AP-MPN)

Accelerated Phase MPN | Blast Phase MPN
Ultragenyx Pharmaceutical Inc

Completed

A Phase 3 Study of UX003 Recombinant Human Betaglucuronidase (rhGUS) Enzyme Replacement Therapy in Patients With Mucopolysaccharidosis Type 7 (MPS 7)

Mucopolysaccharidosis | Sly Syndrome | MPS VII | MPS 7

United States
Alexion Pharmaceuticals

Terminated

A Open Label Study in Previously Studied, SBC-103 Treatment Naïve MPS IIIB Subjects to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 Administered Intravenously (CL01-T)

Mucopolysaccharidosis III, Type B (MPS IIIB) | Sanfilippo B

United Kingdom

Clinical Trials on MPA

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Egypt

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Rare Diseases

Drug Interventions

Dietary Supplements

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