Clinical Trials on Hemoglobinopathies in France

Total 143 results

Hospices Civils de Lyon

Completed

Prevalence of Osteoporosis in Sickle Cell Disease (DREPAN'OS)

Sickle Cell Disease

France
Assistance Publique - Hôpitaux de Paris

Terminated

Angiotensin-converting Enzyme Inhibitors and Early Sickle Cell Renal Disease in Children (MADREPIEC)

Sickle Cell Disease

France
University Hospital, Geneva
Hospices Civils de Lyon; University Hospital, Toulouse

Recruiting

Hyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD) (HBOT-SCD)

Sickle Cell Disease | Vaso-occlusive Crisis | Hyperbaric Oxygen Therapy

France, Switzerland
Vanderbilt-Ingram Cancer Center

Active, not recruiting

Non-Myeloablative Conditioning and Bone Marrow Transplantation

Sickle Cell Disease | Hemoglobinopathies

United States, United Kingdom, France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

The Montreal Cognitive Assessment.Test in Adults With Sickle Cell Disease (EvaCAD)

Sickle Cell Anemia

France
Centre Hospitalier Régional d'Orléans

Recruiting

Interest of Nutritional Care of Children With Sickle Cell Disease on Bone Mineral Density and Body Composition (NUTRIDREP)

Osteoporosis | Sickle Cell Disease | Osteopenia

France
Assistance Publique - Hôpitaux de Paris

Completed

Albuminuria Reduction With Renin Angiotensin System Inhibitors in SCA Patients (RAND)

Sickle Cell Disease

France
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Immunogenicity and Safety Study of Pneumococcal 7-Valent Conjugate Vaccine in Sickle Cell Disease Infants.

Pneumococcal Infections

France
Centre Hospitalier Universitaire de Pointe-a-Pitre
Université des Antilles, LAboratoire ACTES

Completed

Sickle Cell Disease, Neurocognitive Disorders, Social Participation (SOCIODREP)

Sickle Cell Disease

Guadeloupe
Hospices Civils de Lyon

Completed

DREPAMASSE Study - Evaluation of a Newborn Screening for Sickle Cell Disease by Tandem Mass Spectrometry (DREPAMASSE)

Sickle Cell Disease | Infant, Newborn, Disease | Drepanocytosis

France
Assistance Publique - Hôpitaux de Paris
Novartis

Completed

Multicenter Observational Study on Myocardial Iron Overload in 3 Multitransfused Populations (SUFEMYO)

Sickle Cell Disease | Thalassemia | Myelodysplasia

France
Assistance Publique - Hôpitaux de Paris
Mallinckrodt

Completed

Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children (INNOSTAPED)

Sickle Cell Disease | Acute Chest Syndrome

France
Hospital Universitari Vall d'Hebron Research Institute

Active, not recruiting

GenoMed4ALL: Improving SCD Classification and Prognosis by AI (GenoMed4ALL)

Sickle Cell Disorders

Spain, Netherlands, France, Italy
Soutien aux Actions contre les Maladies du Globule...
Pierre Fabre Laboratories; ADDMEDICA SASA

Recruiting

Validation of a Predictive Score of Acute Chest Syndrome (Presev2)

Acute Chest Syndrome | Vaso Occlusive Crisis

France
Assistance Publique - Hôpitaux de Paris

Completed

Allogeneic Genoidentical Stem Cell Transplantation in Children With Sickle-cell Anemia and Cerebral Vasculopathy (DREPAGREFFE)

Sickle Cell Anemia | Cerebrovascular Accident

France
Assistance Publique - Hôpitaux de Paris

Completed

Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome. (Antibio_STA)

Sickle Cell Disease | Acute Chest Syndrome

France
Assistance Publique - Hôpitaux de Paris

Terminated

Non Invasive Positive Pressure Ventilation for Prevention of Acute Chest Syndrome in Sickle Cell Disease (VPACS)

Vaso-occlusive Crisis | Sickle Cell-hemoglobin SS Disease

France
Gamida Cell ltd

Terminated

Allogeneic SCT of CordIn™, in Patients With Hemoglobinopathies

Sickle Cell Disease | Thalassemia

France, United States
Centre Hospitalier Intercommunal Creteil

Recruiting

Pulmonary Ultrasound in the Diagnosis of Acute Thoracic Syndrome in Vaso-occlusive Sickle Cell Crisis (ECHO-STA)

Sickle-Cell Disease Nos With Crisis

France
Assistance Publique - Hôpitaux de Paris

Unknown

Evaluation of the Prevalence of Pulmonary Hypertension in Adult Patients With Sickle Cell Disease (ETENDARD)

Sickle Cell Disease

France
Assistance Publique - Hôpitaux de Paris
LEO Pharma

Completed

Therapeutic Anticoagulation Strategy for Acute Chest Syndrome (TASC)

Anemia | Acute Chest Syndrome | Sickle Cell | Low-Molecular-Weight Heparin

France
Assistance Publique - Hôpitaux de Paris
Mallinckrodt

Completed

Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study) (INOSTA)

Sickle Cell Disease | Acute Chest Syndrome

France
Assistance Publique - Hôpitaux de Paris

Completed

Immunogenicity Study of an Anti-pneumococcal Vaccination Strategy in Patients With Sickle Cells Disease (DREVAC)

Sickle Cells Disease | Invasive Pneumococcal Infections

France
Centre Hospitalier Universitaire de Pointe-a-Pitre

Completed

Epidemiology and Pathophysiological Mechanisms of HTAP in SS and SC Children in Martinique and Guadeloupe. (SAPOTILLE)

Sickle Cell Disease

Martinique
ADDMEDICA SASA

Completed

European Sickle Cell Disease Cohort - Hydroxyurea (ESCORT-HU)

Sickle Cell Disease

France, Germany, French Guiana, Greece, Guadeloupe, Italy, Martinique
Hospices Civils de Lyon

Terminated

Sleep Apnea in Sickle Cell Disease (DREPAPNEE)

Sickle Cell Disease

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Early-goal Directed Automated Red Blood Cell Exchange for Acute Chest Syndrome in Sickle Cell Disease (ARCAD)

Acute Chest Syndrome

France
Celgene

Terminated

Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.

Beta Thalassemia Intermedia | Beta Thalassemia Major

France, United Kingdom, Italy, Greece
University Hospital, Montpellier

Recruiting

Moya Moya Syndrome With or Withtout Sickle Cell Disease (BMM-ScD)

Moya Moya Disease

France
Novartis Pharmaceuticals

Completed

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Transfusional Iron Overload | β-thalassemia Major | Pediatric Rare Anemia

Italy, France
Centre Leon Berard

Recruiting

Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation (EVAADE)

Myelodysplastic Syndromes | Severe Combined Immunodeficiency | Acute Leukemia | Haematological Malignancy | Hemoglobinopathy in Children | Bone Marrow Aplasia

France
bluebird bio

Completed

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Beta-Thalassemia

France, United Kingdom, United States, Thailand, Italy, Germany
bluebird bio

Completed

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia

Beta-Thalassemia

United States, Germany, United Kingdom, France, Greece, Italy
Centre Leon Berard

Withdrawn

A Study to Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Allografts (EVAADE)

Myelodysplastic Syndromes | Severe Combined Immunodeficiency | Acute Leukemia | Haematological Malignancy | Hemoglobinopathy in Children | Bone Marrow Aplasia

France
Sangart

Completed

Safety Study of MP4CO in Adult Sickle Cell Patients

Sickle Cell Disease | Anemia, Sickle Cell | Sickle Cell Anemia | Hemoglobin SC Disease | Sickle Cell Disorders | Sickle Cell Hemoglobin C Disease

United Kingdom, France, Jamaica, Lebanon
ADDMEDICA SASA
International Clinical Trials Association

Recruiting

ESCORT-HU Extension: European Sickle Cell Disease Cohort - Hydroxyurea - Extension Study

Sickle Cell Disease

France, French Guiana, Germany, Greece, Guadeloupe, Italy, Martinique, Réunion
Centre Hospitalier Universitaire de Pointe-a-Pitre
Direction Générale de l'Offre de Soins

Recruiting

Lipid Balance in Adult Sickle Cell Patients (HDL2)

Dyslipidemia | Sickle Cell Disease | Complication

France
Centre Hospitalier Universitaire de Saint Etienne
Claude Bernard University; Laboratoire de Physiologie de l'Exercice; Centre de...

Completed

Evaluation of a Training Program for Homozygous Sickle Cell Disease Patients (EXDRE)

Hemoglobin S Disease | Sickle Cell Hemoglobin C Disease

France
bluebird bio

Enrolling by invitation

Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy

Sickle Cell Disease

United States, France
AstraZeneca

Completed

A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease (Hestia2)

Sickle Cell Disease

United States, Italy, France, United Kingdom, Turkey, Egypt, Lebanon, Kenya
Soutien aux Actions contre les Maladies du Globule...
Novartis

Completed

"Association of Proteinuria and Progression of Kidney Dysfunction in Sickle Cell Disease"Disease (CSEG101A0FR01)

Change in Albumin to Creatinine Ratio and Glomerular Filtration Rate | Progression of Kidney Failure and or All-cause Mortality

France
Alexion

Active, not recruiting

Safety, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of ALXN1820 in Adult Participants With Sickle Cell Disease (PHOENIX)

Sickle Cell Disease (SCD)

United States, France
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease

Sickle Cell Disease | Hemoglobinopathies | Hematological Diseases

United States, Belgium, Canada, France, Germany, Italy, United Kingdom
Vifor (International) Inc.
Fortrea

Completed

Study to Assess Efficacy and Safety of VIT-2763 (Vamifeport) in Subjects With Sickle Cell Disease (ViSionSerenity)

Sickle Cell Disease

United States, France, Greece, Lebanon, United Kingdom
Pfizer

Completed

Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Children With Sickle Cell Disease

Pneumococcal Conjugate Vaccine

France, United States, United Kingdom, Lebanon, Italy, Egypt, Saudi Arabia
Bausch Health Americas, Inc.

Completed

Pharmacokinetics and Pharmacodynamics of Rifaximin Novel Formulations in Patients With Sickle Cell Disease

Sickle Cell Disease

United States, Canada, Kenya
bluebird bio

Active, not recruiting

Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy

Transfusion-dependent Beta-Thalassemia

United States, France, United Kingdom, Australia, Thailand, Italy, Germany, Greece
Hoffmann-La Roche

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOE) in Participants With Sickle Cell Disease (SCD). (CROSSWALK-a)

Sickle Cell Disease

United States, Brazil, Italy, Spain, Kenya, Netherlands, United Kingdom, France, South Africa
Gladwin, Mark, MD
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE) (SCD-CARRE)

Sickle Cell Disease

United States, France, Brazil
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC)

Sickle Cell Disease (SCD)

United States

Clinical Trials on Hemoglobinopathies in France

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CROs in Qatar

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Rare Diseases

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