Clinical Trials on Hemorrhage in Brazil

Total 212 results

Sanofi Pasteur, a Sanofi Company

Completed

Study of a Booster Dose of a Tetravalent Dengue Vaccine in Subjects Who Previously Completed the 3-dose Schedule

Dengue Fever | Dengue Hemorrhagic Fever

Brazil, Colombia, Honduras, Mexico, Puerto Rico
Novo Nordisk A/S

Terminated

Evaluation of Recombinant Factor VIIa in Patients With Severe Bleeding (CONTROL)

Trauma | Acquired Bleeding Disorder

Spain, Hong Kong, Germany, France, United Kingdom, Brazil, Italy, Hungary, Netherlands, United States, Switzerland, Czech Republic, Greece, South Africa
University of Sao Paulo General Hospital

Completed

Early Administration of Fibrinogen in Polytraumatized Patients With Hypofibrinogenemia: a Randomized Feasibility Trial

Trauma | Bleeding Disorder | Fibrinogen; Deficiency, Acquired

Brazil
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Mechanistic Study of Bleeding Risk in Coronary Patients With Cerebrovascular Disease

Coronary Artery Disease | Cerebral Stroke | TIA (Transient Ischemic Attack)

Brazil
Xingshun Qi

Recruiting

Validation of CAGIB Score for In-hospital Mortality of Cirrhotic Patients With Acute Gastrointestinal Bleeding

GastroIntestinal Bleeding

China, Turkey, United States, Brazil, Germany, India, Italy, Mexico
University of Sao Paulo
CSL Behring

Completed

Fibrinogen Concentrate In Children After Cardiac Surgery (FiCCS)

Blood Coagulation Disorders | Cardiac Surgical Procedures | Fibrinogen | Cryoprecipitate

Brazil
The Immunobiological Technology Institute (Bio-Manguinhos)...

Completed

Immunity After Two Doses of Yellow Fever Vaccine (IATDYFV)

Yellow Fever

Brazil
Butantan Institute
Fundação de Amparo à Pesquisa do Estado de São Paulo; Banco Nacional de Desenvolvimento... and other collaborators

Unknown

Phase II Trial to Evaluate Safety and Immunogenicity of a Dengue 1,2,3,4 (Attenuated) Vaccine

Dengue

Brazil
GlaxoSmithKline

Completed

Study to Evaluate the Incidence, Clinical Characteristics and Economic Burden of Dengue in Brazilian Children

Dengue

Brazil
Oswaldo Cruz Foundation

Recruiting

Immunogenicity and Safety of the Yellow Fever Vaccine in HIV Infected Individuals (YF-HIV)

HIV Infections

Brazil
McMaster University
National Health and Medical Research Council, Australia; Canadian Institutes... and other collaborators

Completed

Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial (REVISE)

Gastrointestinal Hemorrhage (Clinically Important, Upper)

Canada, Australia, United States, Brazil, Kuwait, Pakistan, Saudi Arabia, United Kingdom
Grupo de Estudos Multicentricos em Onco-Hematologia

Unknown

Daratumumab Intensified Treatment to Eligible MM New Patients CTD-Dara Induction, Follow by Dara Consolidation (MAXDARA)

Multiple Myeloma Stage I

Brazil
The Immunobiological Technology Institute (Bio-Manguinhos)...

Completed

Clinical Study of Immunity Duration of Yellow Fever Vaccine in Military

Yellow Fever Vaccine

Brazil
National Institute of Allergy and Infectious Diseases...

Recruiting

A Cluster-randomized Trial to EValuate the Efficacy of Wolbachia-InfecTed Aedes Aegypti Mosquitoes in Reducing the Incidence of Arboviral Infection in Brazil (EVITA Dengue)

Dengue Fever

Brazil
Oswaldo Cruz Foundation

Unknown

Complementary Study of the Duration of Post-vaccination Against Yellow Fever Immunity in Children

Yellow Fever

Brazil
Hospital Geral Roberto Santos

Terminated

Rivaroxaban vs Warfarin in Patients With Metallic Prosthesis (RIWA)

Stroke | Valve Heart Disease | Anticoagulants and Bleeding Disorders | Prostheses and Implants

Brazil
The Immunobiological Technology Institute (Bio-Manguinhos)...
Wellcome Trust

Unknown

Duration of Immunity 10 Years After a Dose-response Study With Yellow Fever Vaccine - Complementary Study

Yellow Fever Vaccine

Brazil
University of Campinas, Brazil

Unknown

Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma (METDEXA-MM)

Multiple Myeloma

Brazil
Protecting Brains Saving Futures

Not yet recruiting

Protecting Brains and Saving Futures - the PBSF Protocol (PBSF)

Brain Injuries | Intraventricular Hemorrhage | Congenital Heart Disease | Hypoxic-Ischemic Encephalopathy | Newborn Morbidity | Inborn Errors of Metabolism | Extracorporeal Membrane Oxygenation Complication | Respiratory Complication | Hemodynamic Instability | Nosocomial Infection | Neonatal Seizure | Brain... and other conditions

Brazil
The Immunobiological Technology Institute (Bio-Manguinhos)...
Rockefeller University

Recruiting

Investigation of Serious Adverse Events Following Vaccination Against Yellow Fever: Emphasis on Genetic Basis and Biological Markers

Drug-Related Side Effects and Adverse Reactions

Brazil
The Immunobiological Technology Institute (Bio-Manguinhos)...
Ministry of Health, Brazil

Active, not recruiting

Immunity Period After One Dose of Yellow Fever Vaccine in Adults and Children (Paraiba Study)

Immunity | Yellow Fever Vaccine

Brazil
Federal University of Health Science of Porto Alegre

Unknown

Effect of the Cycloergometer in Patients Undergoing Hematopoietic Stem Cell Transplantation

Lymphoma | Leukemia | Fatigue | Multiple Myeloma | Hematopoietic Stem Cell Transplantation

Brazil
Instituto do Cancer do Estado de São Paulo

Recruiting

Prospective Cohort of Single-dose Radiotherapy for Painful Bone Lesions in Multiple Myeloma

Multiple Myeloma

Brazil
Hospital Israelita Albert Einstein

Unknown

Management of Perioperative Coagulopathy With Thromboelastometry (ROTEM) in Liver Transplant

Liver Cirrhosis | Blood Coagulation Disorders | Evidence of Liver Transplantation

Brazil
The Hospital for Sick Children
Baxter Healthcare Corporation; University of Sao Paulo; University of Campinas... and other collaborators

Completed

Validation of Ultrasound as a Diagnostic Tool for Assessment of Hemophilic Arthropathy of Knees and Ankles

Hemophilia | Hemophilic Arthropathy

Canada, Brazil
Bayer

Active, not recruiting

A Study to Learn How Safe the Study Treatment BAY94-9027 is and How it Affects the Body in Previously Treated Children Aged 7 to Less Than 12 Years With Severe Hemophilia A, a Genetic Bleeding Disorder That is Caused by the Lack of a Protein Called Clotting Factor 8 (FVIII) in the Blood (Alfa-PROTECT)

Hemophilia A | Children | Prophylaxis of Bleeding | Treatment of Bleeding

Canada, United States, Brazil, Italy, Turkey, Argentina, Norway
Novo Nordisk A/S

Terminated

Use of Activated Recombinant Human Factor VII in Cardiac Surgery

Acquired Bleeding Disorder | Cardiac Surgery Requiring Cardiopulmonary Bypass

United States, Spain, Germany, Sweden, United Kingdom, Argentina, Italy, Brazil, Denmark, France, India, Malaysia, Singapore, South Africa
Novo Nordisk A/S

Completed

To Quantify the Range of Main Psychosocial Factors Affecting Patients and Caregivers in Their Daily Lives (HERO)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B | Relatives to/Carers of Patients

Brazil
The Hospital for Sick Children

Completed

Comparing the Burden of Illness of Hemophilia in the Developing and the Developed World

Hemophilia A | Hemophilia B

Canada, Brazil
CSL Behring

Completed

Study of Fibrinogen Concentrate (Human) (FCH) to Control Bleeding During Complex Cardiovascular Surgery (REPLACE)

Surgical Blood Loss | Postoperative Blood Loss

United Kingdom, Canada, Japan, Italy, Poland, Germany, Czech Republic, Austria, Brazil, Denmark, Finland
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Unknown

Education Program for Patients Receiving Oral Anticoagulation

Cardiovascular Disease | Blood Coagulation Disorders, Inherited | Atrial Fibrillation | Venous Thromboses

Brazil
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of a Tetravalent Dengue Vaccine in HIV-Positive Adults

Human Immunodeficiency Virus | Dengue Fever | Dengue Hemorrhagic Fever

Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Bridge or Continue Coumadin for Device Surgery Randomized Controlled Trial (BRUISECONTROL)

Hematoma

Canada, Brazil
University of Sao Paulo General Hospital
Unity Health Toronto; University of Vermont Medical Center

Completed

A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to (SARS-CoV-2) COVID-19 Pandemic (RAPID-BRAZIL)

Severe Acute Respiratory Syndrome | Coronavirus Infection | COVID | Anticoagulants and Bleeding Disorders | Thromboembolism, Venous

Brazil
Bayer

Completed

Study in Women With Idiopathic Menorrhagia to Determine the Reduction in Menstrual Blood Loss (MBL) After Treatment With the Levonorgestrel-releasing Intrauterine System (IUS)

Menorrhagia

United States, Canada, Brazil, Mexico, Argentina
Sanofi Pasteur, a Sanofi Company

Active, not recruiting

Cohort Event Monitoring for Dengvaxia®, CYD-TDV Dengue Vaccine

Dengue Fever | Dengue Hemorrhagic Fever

Brazil, Mexico
Bausch & Lomb Incorporated

Completed

Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage

Diabetic Retinopathy | Vitreous Hemorrhage

Spain, Australia, United Kingdom, Brazil, Hungary, Italy, Netherlands, Poland, South Africa
Grupo de Estudos Multicentricos em Onco-Hematologia

Completed

Thalidomide Plus Dexamethasone as Maintenance Therapy for Multiple Myeloma

Multiple Myeloma

Brazil
Janssen Research & Development, LLC

Approved for marketing

Pre-Approval Access Program for Talquetamab in Relapsed or Refractory Multiple Myeloma

Relapsed or Refractory Multiple Myeloma

Brazil, Germany, Italy, Netherlands, Romania, Switzerland, United Kingdom
Amgen

Completed

Long-term Study of Romiplostim in Thrombocytopenic Pediatric Patients With Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia

United States, Canada, Belgium, Czechia, Mexico, Turkey, Australia, Spain, France, Israel, Hungary, South Africa, Poland, Russian Federation, United Kingdom, Brazil, Switzerland
Novartis Pharmaceuticals

Completed

A Study to Assess the Ability of Eltrombopag to Induce Sustained Response Off Treatment in Subjects With ITP (TAPER)

Immune Thrombocytopenic Purpura (ITP)

Spain, Italy, Greece, Switzerland, United Kingdom, France, Turkey, Russian Federation, Brazil, Austria, Mexico, Oman, Chile, Japan, United States
Grupo de Estudos Multicentricos em Onco-Hematologia

Unknown

Iberoamerican Protocol With Thalidomide in Patients With Symptomatic Newly Diagnosed Multiple Myeloma Over 65 Years

Multiple Myeloma

Brazil
GlaxoSmithKline
Foundation of Tropical Medicine; Goncalo Moniz research center; Evandro Chagas...

Terminated

An Epidemiological Surveillance Study to Evaluate the Incidence of Dengue in Brazil

Dengue

Brazil
Takeda

Withdrawn

A Study of Ixazomib, Thalidomide and Dexamethasone in Newly Diagnosed and Treatment-naive Multiple Myeloma (MM) Participants Non-eligible for Autologous Stem-cell Transplantation (IDEALL)

Multiple Myeloma

Brazil
Cristália Produtos Químicos Farmacêuticos Ltda.

Terminated

Esmolol for the Treatment of Hypertension After Intracerebral Hemorrhage Study (ETHICHS) (ETHICHS)

Hemorrhagic Stroke

Brazil
Population Health Research Institute
Hamilton Health Sciences Corporation

Recruiting

Low INR to Minimize Bleeding With Mechanical Valves Trial (LIMIT)

Bleeding Post-mechanical Valve Replacement | Thromboembolism Post-mechanical Valve Replacement

Canada, Spain, Belgium, Russian Federation, Netherlands, Brazil
Principia Biopharma, a Sanofi Company

Recruiting

Study to Evaluate Rilzabrutinib in Adults and Adolescents With Persistent or Chronic Immune Thrombocytopenia (ITP) (LUNA 3)

Immune Thrombocytopenia

United States, China, Argentina, Australia, Brazil, Canada, France, Hungary, Israel, Korea, Republic of, Mexico, Russian Federation, Singapore, Spain, Thailand, United Kingdom, Austria, Chile, Germany, Italy, Japan, Netherlands, Norway and more
Sanofi Pasteur, a Sanofi Company

Completed

Study of a Novel Tetravalent Dengue Vaccine in Healthy Children and Adolescents Aged 9 to 16 Years in Latin America

Dengue | Dengue Fever | Dengue Hemorrhagic Fever

Colombia, Puerto Rico, Brazil, Honduras, Mexico
Boehringer Ingelheim

Completed

Reversal of Dabigatran Anticoagulant Effect With Idarucizumab

Hemorrhage

United States, Spain, United Kingdom, Norway, Taiwan, Israel, Belgium, Australia, Sweden, Singapore, Germany, Italy, New Zealand, Austria, Japan, Canada, Czechia, Portugal, Netherlands, Korea, Republic of, France, Poland, Colombia, Hong... and more
University of Milano Bicocca
Azienda Ospedaliera San Gerardo di Monza

Completed

The Role of Surgery in Patients With Coronavirus Disease - 19 (COVID-19) Related Thoracic Complications (SThor-CoV-2)

COVID-19 | Pneumothorax | Hemothorax | Abscess | Surgical Complication | Empyema, Pleural | Thoracic

Italy, United States, Brazil, India, United Kingdom

Clinical Trials on Hemorrhage in Brazil

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