Clinical Trials on Hepatic Function Abnormal in Japan

Total 198 results

Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Hepatic Function

Patients With Impaired Hepatic Function

Japan
Taisho Pharmaceutical Co., Ltd.

Completed

A Pharmacokinetic Study of TS-142 in Patients With Hepatic Impairment

Patients With Mild or Moderate Hepatic Impairment

Japan
Kyoto University, Graduate School of Medicine

Unknown

Phase I/II Study of Recombinant Human Hepatocyte Growth Factor in Fulminant Hepatic Failure

Liver Failure, Acute

Japan
Yakult Honsha Co., LTD
Japan Aerospace Exploration Agency

Active, not recruiting

Probiotics on Immune Function and Intestinal Microbiota in Astronauts Under Closed Microgravity Environment

Immune Function and Intestinal Microbiota

Japan
Hamilton Health Sciences Corporation
Tehran University of Medical Sciences; Tohoku University

Recruiting

Japanese Upper GI Symptoms Compared With Iranian and Canadian Patients Presenting

Functional Dyspepsia | Peptic Ulcer | Gastro Esophageal Reflux | Normal Control

Canada, Iran, Islamic Republic of, Japan
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Renal Function and Subjects With Normal Renal Function

Patients With Impaired Renal Function

Japan
Mitsubishi Tanabe Pharma America

Completed

Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Hepatic Impairment

Healthy | Hepatic Impairment

Japan
Astellas Pharma Inc

Completed

ASP8825 - Pharmacokinetics Study in Patients With Impaired Renal Function and Haemodialysis

Patients With Impaired Renal Function and Haemodialysis

Japan
Mochida Pharmaceutical Company, Ltd.
Fuji Yakuhin Co., Ltd.

Completed

Clinical Pharmacology of FYU-981 (Subjects With Hepatic Insufficiency)

Hepatic Insufficiency | Healthy

Japan
Translational Research Center for Medical Innovation...
Johnson & Johnson; Codman & Shurtleff; Eisai Limited; Nihon Medi-Physics Co., Ltd. and other collaborators

Completed

Study to Evaluate Efficacy of Shunt Operation for Idiopathic Normal Pressure Hydrocephalus

Idiopathic Normal Pressure Hydrocephalus

Japan
Eisai Co., Ltd.

Recruiting

Study to Evaluate the Pharmacokinetics (PK) of E7090 (Herein Referred to as Tasurgratinib) and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants

Hepatic Impairment

Japan
Eisai Inc.

Completed

A Post-marketing Observational Study on Risk Factors for Hepatic Encephalopathy in Participants With Unresectable Hepatocellular Carcinoma

Carcinoma, Hepatocellular

Japan
Danone Japan

Completed

Long-term Effectiveness Study on Cholesterol-reducing Activity

Normal and Mild Hypercholesterolemic Subjects

Japan
Viveve Inc.

Completed

VIveve Treatment of the Vaginal Introitus to EValuate Effectiveness (VIVEVE I)

Vaginal Laxity Following Childbirth | Sexual Function Following Childbirth

Canada, Italy, Japan, Spain
Keio University

Withdrawn

Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer

Peptic Ulcers

Japan
Zeria Pharmaceutical

Completed

To Evaluate Efficacy and Safety of Z-215 in Erosive Esophagitis

Esophagitis, Reflux

Japan
Zeria Pharmaceutical

Completed

To Evaluate the Efficacy of Z-338 in Subjects With Functional Dyspepsia

Functional Dyspepsia

Japan
City of Hope Medical Center

Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer (ELUCIDATE)

Hepatocellular Carcinoma | Primary Liver Cancer | Cholangiocarcinoma | Intrahepatic Cholangiocarcinoma | Hepatic Cancer | Hepatic Carcinoma | Primary Liver Carcinoma

United States, Japan
Zeria Pharmaceutical

Recruiting

A Phase III Trial of Z-338 in Paediatric Patients With Functional Dyspepsia

Functional Dyspepsia

Japan
Zeria Pharmaceutical

Completed

The Effect of Z-338 in Subjects With Functional Dyspepsia

Functioanl Dyspepsia

Japan
Zeria Pharmaceutical

Completed

To Verify the Efficacy of Z-338 in Subjects With Functional Dyspepsia

Functional Dyspepsia

Japan
National Hospital Organization Minami Kyoto Hospital

Recruiting

Sleep Hygiene, Sarcopenia, and Cognitive Function in Respiratory Disease

Sarcopenia | Cognitive Function | COPD | Sleep Hygiene | IPF

Japan
Osaka City University

Completed

The Efficacy and Safety Study of Rikkunshito in Patients With Functional Dyspepsia

Functional Dyspepsia

Japan
Astellas Pharma Inc

Completed

A Study of IMAB362 in Japanese Subjects With Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma

Gastric Cancer | Gastro-esophageal Junction (GEJ) Cancer

Japan
National Cancer Center, Japan
Ono Pharmaceutical Co. Ltd; Fiverings Co., Ltd.

Completed

A Phase 1/2 Study of Ramucirumab Plus Nivolumab in Participants With Gastric or GEJ Cancer

Gastric Cancer | Gastroesophageal Junction Region (GEJ) Cancer

Japan
Takeda

Completed

Special Drug Use Surveillance of Vonoprazan for "Maintenance Therapy of Reflux Esophagitis: Long-term Use"

Reflux Esophagitis

Japan
Takeda

Completed

Phase I Open-label Study to Evaluate Pharmacokinetics of TAK-272 in Participants With Renal or Hepatic Impairment

Renal Impairment | Hepatic Impairment

Japan
Astellas Pharma Inc

Completed

A Long-term, Open-label, Uncontrolled Trial of YM443 (Z-338) in Patients With Functional Dyspepsia

Functional Dyspepsia | Dyspepsia

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

An Open Label Pharmacokinetic Study Of Gabapentin In Japanese Subjects With Renal Impairment Including Hemodialysis

PK Properties Of Gabapentin In Subjects With Impaired Renal Function

Japan
Alcon Research

Completed

Investigation of Intraocular Pressure (IOP) Reduction Efficacy of Travoprost Ophthalmic Solution in Patients With Normal Tension Glaucoma

Ocular Hypertension | Normal Tension Glaucoma

Japan
Daiichi Sankyo Co., Ltd.
Quintiles, Inc.; SRL Medisearch Inc.

Completed

DS-5565 Phase III Study for Post-herpetic Neuralgia

Post-Herpetic Neuralgia

Japan
Toray Industries, Inc

Completed

Efficacy and Safety of TRK-700 in Patient With Post-Herpetic Neuralgia

Post-Herpetic Neuralgia

Japan
Tokyo University
Google LLC.

Enrolling by invitation

Impact of Nutrition, Sleep, and Physical Activity on Intellectual Function and Muscle Mass in Older Adults (INSPIOR)

Cognitive Function | MCI | Cognition Disorders in Old Age | Frailty/Sarcopenia

Japan
AstraZeneca

Completed

BE Study Between a Capsule and a Sachet Formulation of D961H by Pharmacodynamics in Japanese Healthy Male Subjects

Gastric Ulcer | Duodenal Ulcer | Reflux Esophagitis | Anastomotic Ulcer | Etc.

Japan
Takeda

Completed

Drug Use Surveillance of Vonoprazan for "Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis"

Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Post-marketing Clinical Study of Rebamipide in Patients With Gastric Ulcer

Stomach Ulcer

Japan
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Patients With Advanced or Refractory Solid Tumors or Lymphoma

Neoplasms | Lymphoma | Adenocarcinoma | Esophagogastric Junction

Japan
Tohoku University

Unknown

Effect of Bifidobacterium on Irritable Bowel Syndrome (PBIBS)

Irritable Bowel Syndrome

Japan
National Cancer Center Hospital East
Daiichi Sankyo Co., Ltd.

Recruiting

Phase 2 Study of T-DXd in the Neoadjuvant Treatment for Patients With HER2 Positive Gastric and GEJ Adenocarcinoma

Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

Japan
Daiichi Sankyo Co., Ltd.
CMIC Co, Ltd. Japan

Completed

DS-5565 Phase III Study for Renal Impairment in Japanese Subjects

Diabetic Peripheral Neuropathic Pain | Post-herpetic Neuralgia

Japan
Takeda

Completed

Special Drug Use Surveillance of Vonoprazan for "Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Low-dose Aspirin: Long-term Use"

Gastric or Duodenal Ulcers

Japan
National Cancer Center Hospital East
Bayer Yakuhin, Ltd.

Active, not recruiting

Clinical Study of Regorafenib and Nivolumab Plus Chemotherapy

Gastric Adenocarcinoma | Esophageal Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

Japan
Takeda

Completed

Special Drug Use Surveillance of Vonoprazan for "Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Non-steroidal Anti-inflammatory Drugs: Long-term Use"

A History of Gastric or Duodenal Ulcers

Japan
Millennium Pharmaceuticals, Inc.

Terminated

MLN0264 in Previously Treated Asian Participants With Advanced Gastrointestinal Carcinoma or Metastatic or Recurrent Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Guanylyl Cyclase C

Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma | Recurrent Gastric Adenocarcinoma | Recurrent Gastroesophageal Junction Adenocarcinoma | Advanced Gastrointestinal Carcinoma | Recurrent Gastrointestinal Carcinoma

Taiwan, Korea, Republic of, Japan
Hamamatsu University

Completed

Pepsinogens as the Early Marker of H. Pylori Eradication

Gastric Ulcer | H. Pylori Infection | Duodnal Ulcer

Japan
Eisai Co., Ltd.

Completed

Rabeprazole Specific Clinical Experience Investigation for the Long-term Combination Therapy With Low-dose Aspirin

Gastric Ulcer | Duodenal Ulcer

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate Efficacy of Ramosetron on Diarrhea-predominant Irritable Bowel Syndrome (IBS) in Male Patients

Irritable Bowel Syndrome

Japan
Taiho Pharmaceutical Co., Ltd.
UCB Pharma

Completed

Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With Famotidine -

Gastroesophageal Reflux

Japan
Astellas Pharma Inc

Completed

A Study to Evaluate Efficacy of YM060 on Diarrhea-predominant Irritable Bowel Syndrome (D-IBS) in Female Patients

Irritable Bowel Syndrome

Japan
Astellas Pharma Inc

Completed

A Preliminary Study to Explore Clinical Endpoints in Patients (Male) With Diarrhea-predominant Irritable Bowel Syndrome

Irritable Bowel Syndrome

Japan

Clinical Trials on Hepatic Function Abnormal in Japan

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