Clinical Trials on Hepatic Insufficiency in United States

Total 4389 results

Icahn School of Medicine at Mount Sinai

Completed

Psychosocial Risks in Liver Transplant Recipients

End Stage Liver Disease

United States
Mayo Clinic

Completed

Cardiopulmonary Exercise Testing in Cirrhotic Patients: a Pilot Study

End Stage Liver Disease

United States
University of Edinburgh
NHS Lothian

Unknown

The Relationship of Initial Liver Profile and Outcome After Transplantation

Liver Failure

United Kingdom
Yale University
Alexion Pharmaceuticals; Ochsner Health System

Withdrawn

Pilot Trial of Eculizumab Therapy to Reduce Preservation Injury in Human Macrosteatotic Liver Transplantation

End Stage Liver Disease

United States
Johns Hopkins University

Active, not recruiting

Pilot Study of the Liver Live Donor Champion Program (LLDC)

End Stage Liver Disease

United States
Massachusetts General Hospital

Completed

A Randomized Controlled Trial of an Advanced Care Planning Video Decision Support Tool for Patients With End-Stage Liver Disease

End Stage Liver Disease

United States
Northwestern University

Terminated

Procurement of Leukapheresis Products From End Stage Liver Disease (ESLD) Patients for Immunological Studies

End Stage Liver Disease

United States
R. Mark Ghobrial, MD
Novartis

Completed

Myfortic, Prograf, and Corticosteroids in de Novo Liver Transplantation

End Stage Liver Disease

United States
Javelin Pharmaceuticals

Completed

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

Hepatic Insufficiency | Healthy | Renal Insufficiency, Chronic

United States, United Kingdom
University of Texas Southwestern Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Terminated

Study of N-Acetylcysteine in Acute Liver Failure (ALF) (ONAC)

Acute Liver Failure | Fulminant Hepatic Failure

United States
LyGenesis, Inc.

Recruiting

Allogenic Hepatocyte Transplantation Into Periduodenal Lymph Nodes

End Stage Liver Disease

United States
Medical College of Wisconsin
National Center for Research Resources (NCRR)

Completed

Effect of Yogurt on Minimal Hepatic Encephalopathy

Cirrhosis | Minimal Hepatic Encephalopathy

United States
NYU Langone Health

Withdrawn

A Randomized Comparison of Rifaximin Versus Lactulose in Hospitalized Cirrhotic Patients With Renal Failure

Hepatic Encephalopathy

United States
The Cleveland Clinic

Recruiting

Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy

Hepatic Encephalopathy

United States
Massachusetts General Hospital
Center for Microbiome Informatics and Therapeutics

Active, not recruiting

Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy

Hepatic Encephalopathy

United States
Hunter Holmes Mcguire Veteran Affairs Medical Center

Completed

A Study of Controlled Lactulose Withdrawal

Hepatic Encephalopathy

United States
University of Michigan
Winterlight Labs

Active, not recruiting

Speech in Hepatic Encephalopathy (HE)

Hepatic Encephalopathy

United States
Mayo Clinic

Completed

Prevention of Hepatic Encephalopathy With Mobile Application Based Lactulose Titration

Hepatic Encephalopathy

United States
NYU Langone Health
Bausch Health Americas, Inc.

Terminated

The Role of Bacterial Overgrowth and Delayed Intestinal Transit in Hepatic Encephalopathy.

Hepatic Encephalopathy

United States
Indiana University

Terminated

Study of Lactulose in Children With Chronic Liver Disease (MHE)

Minimal Hepatic Encephalopathy

United States
Children's Mercy Hospital Kansas City
Eurofins

Recruiting

Correlation of Blood Gene Expression (TruGraf Liver) With Liver Biopsy in Pediatric Liver Transplant Recipients

Liver Failure, Acute | Liver Transplant; Complications

United States
Gilead Sciences

Recruiting

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

Liver Failure | Advanced or Metastatic Solid Tumor

France, United States
William Lee
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

A Multi-Center Trial to Study Acute Liver Failure in Adults (ALFSG)

Acute Liver Failure | Fulminant Hepatic Failure | Acute Liver Injury

United States, Canada
Mallinckrodt

Completed

MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)

Hepatic Cirrhosis | Hepatic Encephalopathy (HE)

United States, Puerto Rico
Bristol-Myers Squibb

Recruiting

A Study to Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies

Hepatic Insufficiency | Neoplasms

Spain, United States, Germany, Argentina, Colombia, Greece
Power Life Sciences Inc.

Not yet recruiting

Revealing Engagement Patterns Among Hepatic Encephalopathy Patients

Hepatic Encephalopathy

United States
Duke University

Recruiting

Deprescribing Proton Pump Inhibitors to Reduce Post-TIPS Hepatic Encephalopathy

Hepatic Encephalopathy

United States
Baylor Research Institute

Unknown

Assessment of Renal Function in Cirrhotic Patients

Liver Failure | Renal Failure

United States
Mylan Specialty, LP

Terminated

Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning

Liver Failure | Amatoxin Poisoning | Amanita Poisoning | Mushroom Poisoning

United States
Mayo Clinic

Recruiting

Disparities Among Liver Transplant Patients

End Stage Liver DIsease

United States
University of Cincinnati

Completed

End Stage Liver Disease and Body Composition Assessment: Utilizing Bioelectric Impedance Analysis (BIA)

End Stage Liver Disease

United States
Pfizer

Completed

Study Examining The Effect Of Hepatic Impairment On Safety, Toleration And How The Body Processes An Experimental Drug

Hepatic Insufficiency | Obesity

United States
Imperial College London

Completed

Adult Stem Cell Therapy in Liver Insufficiency

Liver Cirrhosis

United Kingdom
Horizon Pharma Ireland, Ltd., Dublin Ireland

Terminated

Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic Encephalopathy

Hepatic Encephalopathy

United States
Baylor Research Institute

Active, not recruiting

Quantitative Liver Function Tests Using Cholates

End Stage Liver Disease

United States
Vanderbilt University Medical Center

Enrolling by invitation

Adding Specialist Palliative Care to Transplantation Pilot Trial (ASPECT-Pilot)

End Stage Liver DIsease

United States
Virginia Commonwealth University

Completed

An Integrative Model for Palliative Care in End-Stage Liver Disease

End Stage Liver DIsease

United States
Albert Einstein Healthcare Network

Completed

Monitoring of Symptoms and Cognitive Function Using Telehealth

End Stage Liver Disease

United States
University of Washington
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Flicker App for Minimal Hepatic Encephalopathy

Hepatic Encephalopathy

United States
Hunter Holmes Mcguire Veteran Affairs Medical Center
Bausch Health Americas, Inc.

Completed

Rifaximin in Minimal Hepatic Encephalopathy

Hepatic Encephalopathy

United States
Indivior Inc.

Completed

Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects

Hepatic Impairment | Hepatic Failure | Chronic Hepatitis C Infection With Hepatic Coma

United States
Baylor Research Institute

Recruiting

Functional Assessment in Liver Transplantation (FrAILT)

End Stage Liver Disease | Cirrhosis

United States
Proteonomix, Inc.
University of Medicine and Dentistry of New Jersey; Numoda

Unknown

Mobilization of Stem Cells With G-CSF and Mozobil in Patients With End Stage Liver Disease

End Stage Liver DIsease

United States
University of Miami
Bausch Health Americas, Inc.

Terminated

RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled Trial

Hepatic Encephalopathy

United States
Yale University
Boehringer Ingelheim

Recruiting

Empagliflozin in Patients With Cirrhosis and Ascites (EMPA Liver)

Liver Failure | Cirrhosis

United States
Johns Hopkins University

Completed

Autoregulation Assessment During Liver Transplantation

Liver Failure | Liver Transplantation | Encephalopathy

United States
NYU Langone Health

Withdrawn

Effect of Music on Attention and Prospective Memory in Hepatic Encephalopathy

Hepatic Encephalopathy | Cirrhosis

United States
Stanford University
Neurofit Inc, Mountain View, California

Terminated

Eye Movement Testing for Diagnosing Encephalopathy in Patients With Liver Disease

Hepatic Encephalopathy | Cirrhosis

United States
Rutgers, The State University of New Jersey

Completed

Mobilization of Mesenchymal Stem Cells During Liver Transplantation

Liver Failure | Liver Neoplasm

United States
Eisai Inc.

Completed

Phase 0 Study in Healthy, Hepatic and Renal Impaired Subjects to Obtain Plasma for Lenvatinib Protein Binding

Hepatic Impairment; Renal Impairment

United States

Clinical Trials on Hepatic Insufficiency in United States

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